Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania mexicana

UniProt:

E9B524_LEIMU

TriTrypDb:

LmxM.33.2380

Length:

361

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B524

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B524

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	243	247	PF00656	0.711
CLV_C14_Caspase3-7	283	287	PF00656	0.753
CLV_NRD_NRD_1	296	298	PF00675	0.803
CLV_NRD_NRD_1	314	316	PF00675	0.536
CLV_NRD_NRD_1	43	45	PF00675	0.696
CLV_PCSK_KEX2_1	296	298	PF00082	0.803
CLV_PCSK_KEX2_1	313	315	PF00082	0.557
CLV_PCSK_KEX2_1	337	339	PF00082	0.692
CLV_PCSK_KEX2_1	43	45	PF00082	0.696
CLV_PCSK_PC1ET2_1	337	339	PF00082	0.692
CLV_PCSK_PC1ET2_1	43	45	PF00082	0.696
CLV_PCSK_PC7_1	292	298	PF00082	0.723
CLV_PCSK_SKI1_1	131	135	PF00082	0.692
CLV_PCSK_SKI1_1	16	20	PF00082	0.636
CLV_PCSK_SKI1_1	172	176	PF00082	0.439
CLV_PCSK_SKI1_1	337	341	PF00082	0.735
CLV_PCSK_SKI1_1	6	10	PF00082	0.725
DEG_Nend_UBRbox_3	1	3	PF02207	0.786
DEG_SPOP_SBC_1	306	310	PF00917	0.627
DOC_CKS1_1	7	12	PF01111	0.781
DOC_MAPK_gen_1	184	192	PF00069	0.684
DOC_MAPK_gen_1	296	303	PF00069	0.805
DOC_PP1_RVXF_1	298	304	PF00149	0.516
DOC_PP4_FxxP_1	303	306	PF00568	0.509
DOC_USP7_MATH_1	100	104	PF00917	0.698
DOC_USP7_MATH_1	120	124	PF00917	0.591
DOC_USP7_MATH_1	282	286	PF00917	0.705
DOC_USP7_MATH_1	34	38	PF00917	0.665
DOC_USP7_MATH_1	83	87	PF00917	0.693
DOC_USP7_UBL2_3	45	49	PF12436	0.525
DOC_WW_Pin1_4	30	35	PF00397	0.727
DOC_WW_Pin1_4	302	307	PF00397	0.701
DOC_WW_Pin1_4	324	329	PF00397	0.714
DOC_WW_Pin1_4	6	11	PF00397	0.680
LIG_14-3-3_CanoR_1	166	176	PF00244	0.617
LIG_14-3-3_CanoR_1	194	198	PF00244	0.725
LIG_14-3-3_CanoR_1	28	34	PF00244	0.819
LIG_14-3-3_CanoR_1	296	300	PF00244	0.807
LIG_14-3-3_CanoR_1	61	66	PF00244	0.671
LIG_APCC_ABBAyCdc20_2	16	22	PF00400	0.804
LIG_BRCT_BRCA1_1	139	143	PF00533	0.784
LIG_FHA_1	116	122	PF00498	0.694
LIG_FHA_1	159	165	PF00498	0.755
LIG_FHA_1	330	336	PF00498	0.798
LIG_FHA_1	338	344	PF00498	0.689
LIG_FHA_2	200	206	PF00498	0.754
LIG_FHA_2	278	284	PF00498	0.759
LIG_LIR_Apic_2	302	306	PF02991	0.511
LIG_LIR_Nem_3	132	137	PF02991	0.713
LIG_LIR_Nem_3	94	98	PF02991	0.536
LIG_SH2_SRC	251	254	PF00017	0.698
LIG_SH2_STAP1	251	255	PF00017	0.694
LIG_SH2_STAT3	197	200	PF00017	0.790
LIG_SH2_STAT5	191	194	PF00017	0.655
LIG_SH2_STAT5	197	200	PF00017	0.700
LIG_SH3_3	272	278	PF00018	0.714
LIG_SH3_3	301	307	PF00018	0.724
LIG_SH3_3	65	71	PF00018	0.711
LIG_TRAF2_1	257	260	PF00917	0.809
MOD_CDK_SPK_2	30	35	PF00069	0.727
MOD_CDK_SPxxK_3	6	13	PF00069	0.703
MOD_CK1_1	102	108	PF00069	0.614
MOD_CK1_1	123	129	PF00069	0.544
MOD_CK1_1	14	20	PF00069	0.698
MOD_CK1_1	151	157	PF00069	0.652
MOD_CK1_1	193	199	PF00069	0.791
MOD_CK1_1	30	36	PF00069	0.634
MOD_CK1_1	302	308	PF00069	0.731
MOD_CK1_1	327	333	PF00069	0.722
MOD_CK1_1	75	81	PF00069	0.759
MOD_CK1_1	86	92	PF00069	0.716
MOD_CK1_1	94	100	PF00069	0.719
MOD_CK2_1	199	205	PF00069	0.759
MOD_CK2_1	217	223	PF00069	0.718
MOD_CK2_1	277	283	PF00069	0.733
MOD_CK2_1	284	290	PF00069	0.676
MOD_GlcNHglycan	139	142	PF01048	0.793
MOD_GlcNHglycan	150	153	PF01048	0.672
MOD_GlcNHglycan	252	256	PF01048	0.715
MOD_GlcNHglycan	272	275	PF01048	0.776
MOD_GSK3_1	217	224	PF00069	0.643
MOD_GSK3_1	229	236	PF00069	0.704
MOD_GSK3_1	251	258	PF00069	0.702
MOD_GSK3_1	266	273	PF00069	0.583
MOD_GSK3_1	295	302	PF00069	0.701
MOD_GSK3_1	30	37	PF00069	0.769
MOD_GSK3_1	327	334	PF00069	0.698
MOD_GSK3_1	43	50	PF00069	0.602
MOD_GSK3_1	59	66	PF00069	0.566
MOD_GSK3_1	71	78	PF00069	0.725
MOD_N-GLC_1	105	110	PF02516	0.817
MOD_N-GLC_1	30	35	PF02516	0.532
MOD_N-GLC_1	78	83	PF02516	0.723
MOD_NEK2_1	121	126	PF00069	0.747
MOD_NEK2_1	199	204	PF00069	0.617
MOD_NEK2_1	231	236	PF00069	0.670
MOD_NEK2_1	295	300	PF00069	0.705
MOD_NEK2_1	59	64	PF00069	0.693
MOD_PIKK_1	167	173	PF00454	0.620
MOD_PIKK_1	266	272	PF00454	0.808
MOD_PIKK_1	86	92	PF00454	0.818
MOD_PKA_1	172	178	PF00069	0.410
MOD_PKA_1	337	343	PF00069	0.698
MOD_PKA_1	43	49	PF00069	0.693
MOD_PKA_2	193	199	PF00069	0.676
MOD_PKA_2	27	33	PF00069	0.724
MOD_PKA_2	295	301	PF00069	0.803
MOD_PKA_2	337	343	PF00069	0.808
MOD_PKA_2	43	49	PF00069	0.649
MOD_PKA_2	86	92	PF00069	0.818
MOD_Plk_1	146	152	PF00069	0.759
MOD_Plk_1	200	206	PF00069	0.664
MOD_Plk_1	217	223	PF00069	0.817
MOD_Plk_1	78	84	PF00069	0.725
MOD_Plk_2-3	217	223	PF00069	0.817
MOD_Plk_4	14	20	PF00069	0.791
MOD_Plk_4	193	199	PF00069	0.500
MOD_Plk_4	299	305	PF00069	0.711
MOD_Plk_4	63	69	PF00069	0.791
MOD_ProDKin_1	30	36	PF00069	0.728
MOD_ProDKin_1	302	308	PF00069	0.699
MOD_ProDKin_1	324	330	PF00069	0.711
MOD_ProDKin_1	6	12	PF00069	0.679
TRG_ER_diArg_1	295	297	PF00400	0.731
TRG_ER_diArg_1	312	315	PF00400	0.620
TRG_ER_diLys_1	356	361	PF00400	0.694
TRG_Pf-PMV_PEXEL_1	131	135	PF00026	0.717
TRG_PTS1	358	361	PF00515	0.518

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IAB5	Leptomonas seymouri	36%	100%
A0A3S7X7Y4	Leishmania donovani	89%	100%
A4HAU9	Leishmania braziliensis	66%	100%
A4IAM0	Leishmania infantum	90%	100%
Q4Q2W2	Leishmania major	87%	100%