LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, unknown function
Species:
Leishmania mexicana
UniProt:
E9B521_LEIMU
TriTrypDb:
LmxM.33.2350
Length:
206

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 9
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 6
NetGPI no yes: 0, no: 6
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B521
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B521

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 48 50 PF00675 0.624
CLV_PCSK_FUR_1 46 50 PF00082 0.624
CLV_PCSK_KEX2_1 48 50 PF00082 0.601
CLV_PCSK_SKI1_1 38 42 PF00082 0.595
DEG_Nend_Nbox_1 1 3 PF02207 0.706
DEG_SPOP_SBC_1 12 16 PF00917 0.570
DOC_CYCLIN_RxL_1 167 178 PF00134 0.490
DOC_MAPK_gen_1 99 108 PF00069 0.763
DOC_USP7_MATH_1 125 129 PF00917 0.477
DOC_USP7_MATH_1 26 30 PF00917 0.627
DOC_WW_Pin1_4 84 89 PF00397 0.552
LIG_14-3-3_CanoR_1 101 107 PF00244 0.541
LIG_eIF4E_1 199 205 PF01652 0.657
LIG_FHA_1 103 109 PF00498 0.759
LIG_FHA_1 113 119 PF00498 0.576
LIG_FHA_1 121 127 PF00498 0.461
LIG_FHA_1 14 20 PF00498 0.574
LIG_FHA_1 186 192 PF00498 0.706
LIG_FHA_2 187 193 PF00498 0.596
LIG_LIR_Gen_1 59 68 PF02991 0.584
LIG_LIR_Nem_3 192 196 PF02991 0.573
LIG_LIR_Nem_3 59 63 PF02991 0.557
LIG_SH2_STAP1 96 100 PF00017 0.676
LIG_SH3_2 88 93 PF14604 0.489
LIG_SH3_3 85 91 PF00018 0.771
LIG_SUMO_SIM_anti_2 104 110 PF11976 0.752
MOD_CK1_1 14 20 PF00069 0.691
MOD_CK1_1 186 192 PF00069 0.452
MOD_CK2_1 84 90 PF00069 0.532
MOD_GlcNHglycan 185 188 PF01048 0.440
MOD_GSK3_1 11 18 PF00069 0.690
MOD_GSK3_1 120 127 PF00069 0.617
MOD_GSK3_1 199 206 PF00069 0.448
MOD_LATS_1 9 15 PF00433 0.691
MOD_N-GLC_1 84 89 PF02516 0.552
MOD_N-GLC_2 65 67 PF02516 0.398
MOD_NEK2_1 158 163 PF00069 0.375
MOD_NEK2_1 185 190 PF00069 0.686
MOD_NEK2_1 19 24 PF00069 0.693
MOD_NEK2_1 191 196 PF00069 0.657
MOD_PK_1 48 54 PF00069 0.619
MOD_PKA_1 48 54 PF00069 0.619
MOD_PKA_2 48 54 PF00069 0.697
MOD_PKB_1 46 54 PF00069 0.620
MOD_PKB_1 99 107 PF00069 0.587
MOD_Plk_1 191 197 PF00069 0.731
MOD_Plk_4 104 110 PF00069 0.692
MOD_Plk_4 161 167 PF00069 0.607
MOD_ProDKin_1 84 90 PF00069 0.554
TRG_ER_diArg_1 47 49 PF00400 0.624
TRG_ER_diArg_1 93 96 PF00400 0.573

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1IC33 Leptomonas seymouri 34% 100%
A0A3Q8IHA0 Leishmania donovani 84% 100%
A4HAU7 Leishmania braziliensis 60% 100%
A4IA14 Leishmania infantum 84% 100%
Q4Q2W5 Leishmania major 81% 100%

Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS