Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania mexicana

UniProt:

E9B507_LEIMU

TriTrypDb:

LmxM.33.2210

Length:

634

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 3
NetGPI	no	yes: 0, no: 3

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B507

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B507

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	156	160	PF00656	0.671
CLV_C14_Caspase3-7	213	217	PF00656	0.523
CLV_C14_Caspase3-7	600	604	PF00656	0.534
CLV_NRD_NRD_1	426	428	PF00675	0.812
CLV_PCSK_KEX2_1	426	428	PF00082	0.812
CLV_PCSK_SKI1_1	229	233	PF00082	0.548
CLV_PCSK_SKI1_1	312	316	PF00082	0.811
CLV_PCSK_SKI1_1	36	40	PF00082	0.627
DEG_Nend_UBRbox_2	1	3	PF02207	0.556
DEG_SCF_FBW7_1	129	136	PF00400	0.835
DEG_SCF_FBW7_1	234	240	PF00400	0.831
DEG_SCF_FBW7_1	386	392	PF00400	0.813
DEG_SPOP_SBC_1	490	494	PF00917	0.717
DOC_CDC14_PxL_1	110	118	PF14671	0.789
DOC_CKS1_1	21	26	PF01111	0.690
DOC_CKS1_1	234	239	PF01111	0.834
DOC_CKS1_1	374	379	PF01111	0.820
DOC_CKS1_1	386	391	PF01111	0.618
DOC_CKS1_1	66	71	PF01111	0.835
DOC_CKS1_1	96	101	PF01111	0.798
DOC_MAPK_MEF2A_6	30	37	PF00069	0.757
DOC_MAPK_MEF2A_6	501	510	PF00069	0.827
DOC_MAPK_NFAT4_5	30	38	PF00069	0.756
DOC_PP2B_LxvP_1	408	411	PF13499	0.657
DOC_PP2B_LxvP_1	420	423	PF13499	0.672
DOC_PP4_FxxP_1	21	24	PF00568	0.809
DOC_PP4_FxxP_1	409	412	PF00568	0.608
DOC_PP4_FxxP_1	96	99	PF00568	0.798
DOC_USP7_MATH_1	133	137	PF00917	0.835
DOC_USP7_MATH_1	141	145	PF00917	0.709
DOC_USP7_MATH_1	176	180	PF00917	0.806
DOC_USP7_MATH_1	237	241	PF00917	0.833
DOC_USP7_MATH_1	314	318	PF00917	0.675
DOC_USP7_MATH_1	340	344	PF00917	0.705
DOC_USP7_MATH_1	389	393	PF00917	0.819
DOC_USP7_MATH_1	491	495	PF00917	0.749
DOC_USP7_MATH_1	506	510	PF00917	0.687
DOC_USP7_MATH_1	512	516	PF00917	0.727
DOC_USP7_MATH_1	566	570	PF00917	0.606
DOC_USP7_MATH_1	578	582	PF00917	0.681
DOC_USP7_MATH_1	604	608	PF00917	0.526
DOC_WW_Pin1_4	1	6	PF00397	0.673
DOC_WW_Pin1_4	129	134	PF00397	0.838
DOC_WW_Pin1_4	135	140	PF00397	0.737
DOC_WW_Pin1_4	159	164	PF00397	0.793
DOC_WW_Pin1_4	20	25	PF00397	0.501
DOC_WW_Pin1_4	219	224	PF00397	0.809
DOC_WW_Pin1_4	233	238	PF00397	0.608
DOC_WW_Pin1_4	246	251	PF00397	0.645
DOC_WW_Pin1_4	286	291	PF00397	0.658
DOC_WW_Pin1_4	306	311	PF00397	0.819
DOC_WW_Pin1_4	373	378	PF00397	0.670
DOC_WW_Pin1_4	385	390	PF00397	0.680
DOC_WW_Pin1_4	393	398	PF00397	0.491
DOC_WW_Pin1_4	45	50	PF00397	0.751
DOC_WW_Pin1_4	470	475	PF00397	0.840
DOC_WW_Pin1_4	482	487	PF00397	0.652
DOC_WW_Pin1_4	502	507	PF00397	0.503
DOC_WW_Pin1_4	56	61	PF00397	0.619
DOC_WW_Pin1_4	584	589	PF00397	0.819
DOC_WW_Pin1_4	65	70	PF00397	0.710
DOC_WW_Pin1_4	81	86	PF00397	0.556
DOC_WW_Pin1_4	95	100	PF00397	0.538
LIG_14-3-3_CanoR_1	134	142	PF00244	0.567
LIG_14-3-3_CanoR_1	462	472	PF00244	0.708
LIG_14-3-3_CanoR_1	52	61	PF00244	0.807
LIG_14-3-3_CanoR_1	536	542	PF00244	0.531
LIG_14-3-3_CanoR_1	546	551	PF00244	0.517
LIG_BRCT_BRCA1_1	258	262	PF00533	0.844
LIG_BRCT_BRCA1_1	288	292	PF00533	0.625
LIG_Clathr_ClatBox_1	333	337	PF01394	0.566
LIG_CSL_BTD_1	234	237	PF09270	0.833
LIG_eIF4E_1	110	116	PF01652	0.520
LIG_FHA_1	162	168	PF00498	0.524
LIG_FHA_1	181	187	PF00498	0.662
LIG_FHA_1	2	8	PF00498	0.568
LIG_FHA_1	24	30	PF00498	0.633
LIG_FHA_1	286	292	PF00498	0.543
LIG_FHA_1	355	361	PF00498	0.830
LIG_FHA_1	381	387	PF00498	0.685
LIG_FHA_1	540	546	PF00498	0.781
LIG_FHA_1	625	631	PF00498	0.767
LIG_FXI_DFP_1	263	267	PF00024	0.825
LIG_HP1_1	506	510	PF01393	0.828
LIG_LIR_Apic_2	19	24	PF02991	0.812
LIG_LIR_Apic_2	407	412	PF02991	0.608
LIG_LIR_Apic_2	94	99	PF02991	0.796
LIG_LIR_Gen_1	152	163	PF02991	0.536
LIG_LIR_Gen_1	414	425	PF02991	0.530
LIG_LIR_Gen_1	84	93	PF02991	0.667
LIG_LIR_Nem_3	107	113	PF02991	0.792
LIG_LIR_Nem_3	152	158	PF02991	0.585
LIG_LIR_Nem_3	289	295	PF02991	0.623
LIG_LIR_Nem_3	414	420	PF02991	0.524
LIG_LIR_Nem_3	609	615	PF02991	0.808
LIG_LIR_Nem_3	84	90	PF02991	0.669
LIG_LYPXL_yS_3	113	116	PF13949	0.786
LIG_PDZ_Class_1	629	634	PF00595	0.760
LIG_PDZ_Wminus1_1	632	634	PF00595	0.757
LIG_Pex14_1	537	541	PF04695	0.799
LIG_Pex14_2	262	266	PF04695	0.833
LIG_Pex14_2	629	633	PF04695	0.758
LIG_SH2_CRK	591	595	PF00017	0.687
LIG_SH2_STAT5	205	208	PF00017	0.817
LIG_SH2_STAT5	379	382	PF00017	0.672
LIG_SH2_STAT5	416	419	PF00017	0.799
LIG_SH2_STAT5	612	615	PF00017	0.813
LIG_SH2_STAT5	628	631	PF00017	0.508
LIG_SH3_1	562	568	PF00018	0.547
LIG_SH3_3	2	8	PF00018	0.837
LIG_SH3_3	231	237	PF00018	0.828
LIG_SH3_3	492	498	PF00018	0.809
LIG_SH3_3	55	61	PF00018	0.830
LIG_SH3_3	560	566	PF00018	0.551
LIG_SxIP_EBH_1	98	108	PF03271	0.793
LIG_TYR_ITSM	412	419	PF00017	0.519
LIG_WW_2	497	500	PF00397	0.546
MOD_CDC14_SPxK_1	222	225	PF00782	0.813
MOD_CDC14_SPxK_1	27	30	PF00782	0.758
MOD_CDC14_SPxK_1	309	312	PF00782	0.819
MOD_CDK_SPK_2	129	134	PF00069	0.704
MOD_CDK_SPK_2	373	378	PF00069	0.816
MOD_CDK_SPxK_1	219	225	PF00069	0.811
MOD_CDK_SPxK_1	24	30	PF00069	0.768
MOD_CDK_SPxK_1	306	312	PF00069	0.821
MOD_CDK_SPxK_1	95	101	PF00069	0.798
MOD_CDK_SPxxK_3	45	52	PF00069	0.792
MOD_CDK_SPxxK_3	67	74	PF00069	0.835
MOD_CK1_1	181	187	PF00069	0.582
MOD_CK1_1	211	217	PF00069	0.742
MOD_CK1_1	240	246	PF00069	0.841
MOD_CK1_1	305	311	PF00069	0.684
MOD_CK1_1	332	338	PF00069	0.569
MOD_CK1_1	404	410	PF00069	0.776
MOD_CK1_1	449	455	PF00069	0.553
MOD_CK1_1	540	546	PF00069	0.808
MOD_CK1_1	56	62	PF00069	0.728
MOD_CK1_1	570	576	PF00069	0.716
MOD_CK2_1	184	190	PF00069	0.724
MOD_CK2_1	250	256	PF00069	0.850
MOD_CK2_1	474	480	PF00069	0.840
MOD_CK2_1	86	92	PF00069	0.815
MOD_DYRK1A_RPxSP_1	233	237	PF00069	0.834
MOD_GlcNHglycan	110	113	PF01048	0.789
MOD_GlcNHglycan	143	146	PF01048	0.732
MOD_GlcNHglycan	178	181	PF01048	0.544
MOD_GlcNHglycan	18	21	PF01048	0.770
MOD_GlcNHglycan	206	209	PF01048	0.797
MOD_GlcNHglycan	253	256	PF01048	0.647
MOD_GlcNHglycan	304	307	PF01048	0.820
MOD_GlcNHglycan	368	372	PF01048	0.684
MOD_GlcNHglycan	448	451	PF01048	0.681
MOD_GlcNHglycan	55	58	PF01048	0.681
MOD_GlcNHglycan	553	556	PF01048	0.794
MOD_GlcNHglycan	624	627	PF01048	0.633
MOD_GlcNHglycan	81	84	PF01048	0.707
MOD_GSK3_1	100	107	PF00069	0.645
MOD_GSK3_1	125	132	PF00069	0.828
MOD_GSK3_1	133	140	PF00069	0.705
MOD_GSK3_1	16	23	PF00069	0.683
MOD_GSK3_1	176	183	PF00069	0.683
MOD_GSK3_1	204	211	PF00069	0.813
MOD_GSK3_1	229	236	PF00069	0.823
MOD_GSK3_1	246	253	PF00069	0.788
MOD_GSK3_1	302	309	PF00069	0.818
MOD_GSK3_1	310	317	PF00069	0.698
MOD_GSK3_1	322	329	PF00069	0.492
MOD_GSK3_1	363	370	PF00069	0.688
MOD_GSK3_1	385	392	PF00069	0.813
MOD_GSK3_1	41	48	PF00069	0.732
MOD_GSK3_1	470	477	PF00069	0.841
MOD_GSK3_1	482	489	PF00069	0.653
MOD_GSK3_1	502	509	PF00069	0.503
MOD_GSK3_1	52	59	PF00069	0.608
MOD_GSK3_1	540	547	PF00069	0.755
MOD_GSK3_1	566	573	PF00069	0.651
MOD_GSK3_1	598	605	PF00069	0.793
MOD_GSK3_1	615	622	PF00069	0.503
MOD_GSK3_1	7	14	PF00069	0.664
MOD_GSK3_1	91	98	PF00069	0.650
MOD_N-GLC_1	16	21	PF02516	0.798
MOD_N-GLC_1	482	487	PF02516	0.846
MOD_N-GLC_1	510	515	PF02516	0.555
MOD_NEK2_1	11	16	PF00069	0.558
MOD_NEK2_1	116	121	PF00069	0.783
MOD_NEK2_1	401	406	PF00069	0.811
MOD_NEK2_1	510	515	PF00069	0.690
MOD_NEK2_1	557	562	PF00069	0.747
MOD_NEK2_1	596	601	PF00069	0.680
MOD_NEK2_1	619	624	PF00069	0.713
MOD_NEK2_1	629	634	PF00069	0.666
MOD_NEK2_2	491	496	PF00069	0.577
MOD_PIKK_1	178	184	PF00454	0.694
MOD_PIKK_1	240	246	PF00454	0.841
MOD_PIKK_1	411	417	PF00454	0.647
MOD_PIKK_1	463	469	PF00454	0.704
MOD_PIKK_1	510	516	PF00454	0.691
MOD_PIKK_1	570	576	PF00454	0.703
MOD_PKA_2	133	139	PF00069	0.700
MOD_PKA_2	176	182	PF00069	0.813
MOD_PKA_2	364	370	PF00069	0.552
MOD_PKA_2	463	469	PF00069	0.656
MOD_PKA_2	615	621	PF00069	0.792
MOD_PKB_1	227	235	PF00069	0.820
MOD_PKB_1	77	85	PF00069	0.560
MOD_Plk_1	16	22	PF00069	0.555
MOD_Plk_1	217	223	PF00069	0.805
MOD_Plk_1	300	306	PF00069	0.539
MOD_Plk_1	326	332	PF00069	0.814
MOD_Plk_1	557	563	PF00069	0.562
MOD_Plk_1	608	614	PF00069	0.785
MOD_Plk_2-3	322	328	PF00069	0.817
MOD_Plk_4	329	335	PF00069	0.677
MOD_Plk_4	389	395	PF00069	0.820
MOD_Plk_4	404	410	PF00069	0.560
MOD_Plk_4	608	614	PF00069	0.804
MOD_Plk_4	624	630	PF00069	0.509
MOD_ProDKin_1	1	7	PF00069	0.674
MOD_ProDKin_1	129	135	PF00069	0.836
MOD_ProDKin_1	137	143	PF00069	0.710
MOD_ProDKin_1	159	165	PF00069	0.792
MOD_ProDKin_1	20	26	PF00069	0.493
MOD_ProDKin_1	219	225	PF00069	0.811
MOD_ProDKin_1	233	239	PF00069	0.608
MOD_ProDKin_1	246	252	PF00069	0.645
MOD_ProDKin_1	286	292	PF00069	0.658
MOD_ProDKin_1	306	312	PF00069	0.821
MOD_ProDKin_1	373	379	PF00069	0.671
MOD_ProDKin_1	385	391	PF00069	0.681
MOD_ProDKin_1	393	399	PF00069	0.490
MOD_ProDKin_1	45	51	PF00069	0.755
MOD_ProDKin_1	470	476	PF00069	0.842
MOD_ProDKin_1	482	488	PF00069	0.650
MOD_ProDKin_1	502	508	PF00069	0.503
MOD_ProDKin_1	56	62	PF00069	0.621
MOD_ProDKin_1	584	590	PF00069	0.820
MOD_ProDKin_1	65	71	PF00069	0.709
MOD_ProDKin_1	81	87	PF00069	0.559
MOD_ProDKin_1	95	101	PF00069	0.539
TRG_DiLeu_BaLyEn_6	111	116	PF01217	0.518
TRG_DiLeu_BaLyEn_6	33	38	PF01217	0.759
TRG_DiLeu_BaLyEn_6	518	523	PF01217	0.553
TRG_ENDOCYTIC_2	113	116	PF00928	0.786
TRG_ENDOCYTIC_2	155	158	PF00928	0.545
TRG_ENDOCYTIC_2	416	419	PF00928	0.530
TRG_ENDOCYTIC_2	591	594	PF00928	0.556
TRG_ER_diArg_1	224	227	PF00400	0.816
TRG_ER_diArg_1	425	427	PF00400	0.553
TRG_ER_diArg_1	545	548	PF00400	0.757
TRG_NES_CRM1_1	326	337	PF08389	0.554
TRG_Pf-PMV_PEXEL_1	261	265	PF00026	0.834

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A4I9Z3	Leishmania infantum	80%	66%
Q4Q2X9	Leishmania major	80%	100%