Uncharacterized protein (Putative eukaryotic translation initiation factor 2-alpha kinase)

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

eukaryotic translation initiation factor 2-alpha kinase 2

Species:

Leishmania mexicana

UniProt:

E9B501_LEIMU

TriTrypDb:

LmxM.33.2150

Length:

1469

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Cellular components
Term	Name	Level	Count
GO:0005768	endosome	7	1
GO:0005829	cytosol	2	1
GO:0016020	membrane	2	3
GO:0031090	organelle membrane	3	1
GO:0031410	cytoplasmic vesicle	6	1
GO:0031982	vesicle	4	1
GO:0043226	organelle	2	1
GO:0043227	membrane-bounded organelle	3	1
GO:0043229	intracellular organelle	3	1
GO:0043231	intracellular membrane-bounded organelle	4	1
GO:0097708	intracellular vesicle	5	1
GO:0110165	cellular anatomical entity	1	3
GO:1990578	perinuclear endoplasmic reticulum membrane	4	1

Expansion

Sequence features

E9B501

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

No structure information available for this entry

Related structures:

Function

Biological processes
Term	Name	Level	Count
GO:0006468	protein phosphorylation	5	7
GO:0006793	phosphorus metabolic process	3	7
GO:0006796	phosphate-containing compound metabolic process	4	7
GO:0006807	nitrogen compound metabolic process	2	7
GO:0008152	metabolic process	1	7
GO:0009987	cellular process	1	7
GO:0016310	phosphorylation	5	7
GO:0019538	protein metabolic process	3	7
GO:0036211	protein modification process	4	7
GO:0043170	macromolecule metabolic process	3	7
GO:0043412	macromolecule modification	4	7
GO:0044237	cellular metabolic process	2	7
GO:0044238	primary metabolic process	2	7
GO:0071704	organic substance metabolic process	2	7
GO:1901564	organonitrogen compound metabolic process	3	7
GO:0001932	regulation of protein phosphorylation	7	1
GO:0006417	regulation of translation	6	1
GO:0006446	regulation of translational initiation	7	1
GO:0009889	regulation of biosynthetic process	4	1
GO:0010468	regulation of gene expression	5	1
GO:0010556	regulation of macromolecule biosynthetic process	5	1
GO:0010608	post-transcriptional regulation of gene expression	6	1
GO:0010998	regulation of translational initiation by eIF2 alpha phosphorylation	6	1
GO:0010999	regulation of eIF2 alpha phosphorylation by heme	5	1
GO:0019220	regulation of phosphate metabolic process	6	1
GO:0019222	regulation of metabolic process	3	1
GO:0031323	regulation of cellular metabolic process	4	1
GO:0031326	regulation of cellular biosynthetic process	5	1
GO:0031399	regulation of protein modification process	6	1
GO:0034248	regulation of amide metabolic process	5	1
GO:0042325	regulation of phosphorylation	7	1
GO:0043555	regulation of translation in response to stress	7	1
GO:0043558	regulation of translational initiation in response to stress	8	1
GO:0048583	regulation of response to stimulus	3	1
GO:0050789	regulation of biological process	2	1
GO:0050794	regulation of cellular process	3	1
GO:0051171	regulation of nitrogen compound metabolic process	4	1
GO:0051174	regulation of phosphorus metabolic process	5	1
GO:0051246	regulation of protein metabolic process	5	1
GO:0060255	regulation of macromolecule metabolic process	4	1
GO:0065007	biological regulation	1	1
GO:0080090	regulation of primary metabolic process	4	1
GO:0080134	regulation of response to stress	4	1
GO:0080135	regulation of cellular response to stress	4	1
GO:2000112	obsolete regulation of cellular macromolecule biosynthetic process	6	1

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	7
GO:0003676	nucleic acid binding	3	4
GO:0003743	translation initiation factor activity	4	4
GO:0003824	catalytic activity	1	7
GO:0004672	protein kinase activity	3	7
GO:0005488	binding	1	7
GO:0005524	ATP binding	5	7
GO:0008135	translation factor activity, RNA binding	3	4
GO:0016301	kinase activity	4	7
GO:0016740	transferase activity	2	7
GO:0016772	transferase activity, transferring phosphorus-containing groups	3	7
GO:0016773	phosphotransferase activity, alcohol group as acceptor	4	7
GO:0017076	purine nucleotide binding	4	7
GO:0030554	adenyl nucleotide binding	5	7
GO:0032553	ribonucleotide binding	3	7
GO:0032555	purine ribonucleotide binding	4	7
GO:0032559	adenyl ribonucleotide binding	5	7
GO:0035639	purine ribonucleoside triphosphate binding	4	7
GO:0036094	small molecule binding	2	7
GO:0043167	ion binding	2	7
GO:0043168	anion binding	3	7
GO:0045182	translation regulator activity	1	5
GO:0090079	translation regulator activity, nucleic acid binding	2	4
GO:0097159	organic cyclic compound binding	2	7
GO:0097367	carbohydrate derivative binding	2	7
GO:0140096	catalytic activity, acting on a protein	2	7
GO:1901265	nucleoside phosphate binding	3	7
GO:1901363	heterocyclic compound binding	2	7
GO:0004674	protein serine/threonine kinase activity	4	1
GO:0004683	calmodulin-dependent protein kinase activity	5	1
GO:0004686	elongation factor-2 kinase activity	6	1
GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity	2	1
GO:0020037	heme binding	4	1
GO:0046906	tetrapyrrole binding	3	1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	1010	1014	PF00656	0.454
CLV_C14_Caspase3-7	1318	1322	PF00656	0.698
CLV_C14_Caspase3-7	1376	1380	PF00656	0.357
CLV_C14_Caspase3-7	168	172	PF00656	0.369
CLV_C14_Caspase3-7	532	536	PF00656	0.335
CLV_C14_Caspase3-7	993	997	PF00656	0.613
CLV_NRD_NRD_1	1109	1111	PF00675	0.346
CLV_NRD_NRD_1	1218	1220	PF00675	0.349
CLV_NRD_NRD_1	1280	1282	PF00675	0.483
CLV_NRD_NRD_1	1400	1402	PF00675	0.756
CLV_NRD_NRD_1	199	201	PF00675	0.560
CLV_NRD_NRD_1	20	22	PF00675	0.457
CLV_NRD_NRD_1	25	27	PF00675	0.560
CLV_NRD_NRD_1	357	359	PF00675	0.699
CLV_NRD_NRD_1	529	531	PF00675	0.523
CLV_PCSK_KEX2_1	1108	1110	PF00082	0.346
CLV_PCSK_KEX2_1	1391	1393	PF00082	0.721
CLV_PCSK_KEX2_1	1399	1401	PF00082	0.724
CLV_PCSK_KEX2_1	1457	1459	PF00082	0.665
CLV_PCSK_KEX2_1	199	201	PF00082	0.560
CLV_PCSK_KEX2_1	20	22	PF00082	0.463
CLV_PCSK_KEX2_1	24	26	PF00082	0.551
CLV_PCSK_KEX2_1	30	32	PF00082	0.522
CLV_PCSK_KEX2_1	357	359	PF00082	0.712
CLV_PCSK_KEX2_1	529	531	PF00082	0.523
CLV_PCSK_PC1ET2_1	1108	1110	PF00082	0.346
CLV_PCSK_PC1ET2_1	1391	1393	PF00082	0.780
CLV_PCSK_PC1ET2_1	1457	1459	PF00082	0.637
CLV_PCSK_PC1ET2_1	30	32	PF00082	0.523
CLV_PCSK_PC7_1	20	26	PF00082	0.533
CLV_PCSK_SKI1_1	1064	1068	PF00082	0.376
CLV_PCSK_SKI1_1	1179	1183	PF00082	0.330
CLV_PCSK_SKI1_1	1205	1209	PF00082	0.346
CLV_PCSK_SKI1_1	1219	1223	PF00082	0.346
CLV_PCSK_SKI1_1	341	345	PF00082	0.612
CLV_PCSK_SKI1_1	41	45	PF00082	0.415
CLV_PCSK_SKI1_1	466	470	PF00082	0.568
CLV_PCSK_SKI1_1	600	604	PF00082	0.526
CLV_PCSK_SKI1_1	770	774	PF00082	0.506
CLV_Separin_Metazoa	1061	1065	PF03568	0.619
DEG_APCC_DBOX_1	1218	1226	PF00400	0.558
DEG_MDM2_SWIB_1	969	977	PF02201	0.546
DEG_SCF_FBW7_1	783	790	PF00400	0.673
DEG_SPOP_SBC_1	1287	1291	PF00917	0.717
DEG_SPOP_SBC_1	1294	1298	PF00917	0.642
DEG_SPOP_SBC_1	1357	1361	PF00917	0.535
DEG_SPOP_SBC_1	317	321	PF00917	0.559
DEG_SPOP_SBC_1	370	374	PF00917	0.538
DEG_SPOP_SBC_1	416	420	PF00917	0.470
DEG_SPOP_SBC_1	782	786	PF00917	0.648
DEG_SPOP_SBC_1	787	791	PF00917	0.695
DEG_SPOP_SBC_1	825	829	PF00917	0.676
DOC_CDC14_PxL_1	459	467	PF14671	0.476
DOC_CDC14_PxL_1	492	500	PF14671	0.304
DOC_CKS1_1	1440	1445	PF01111	0.462
DOC_CKS1_1	567	572	PF01111	0.389
DOC_CKS1_1	763	768	PF01111	0.586
DOC_CYCLIN_yCln2_LP_2	1384	1390	PF00134	0.360
DOC_CYCLIN_yCln2_LP_2	143	149	PF00134	0.401
DOC_CYCLIN_yCln2_LP_2	572	578	PF00134	0.274
DOC_MAPK_gen_1	1219	1230	PF00069	0.694
DOC_MAPK_gen_1	1281	1288	PF00069	0.558
DOC_MAPK_gen_1	199	205	PF00069	0.365
DOC_MAPK_MEF2A_6	1223	1232	PF00069	0.696
DOC_MAPK_MEF2A_6	144	151	PF00069	0.395
DOC_MAPK_MEF2A_6	273	280	PF00069	0.351
DOC_MAPK_MEF2A_6	41	48	PF00069	0.548
DOC_MAPK_NFAT4_5	273	281	PF00069	0.351
DOC_MAPK_NFAT4_5	41	49	PF00069	0.619
DOC_PP1_RVXF_1	39	46	PF00149	0.411
DOC_PP1_RVXF_1	798	804	PF00149	0.576
DOC_PP1_RVXF_1	913	919	PF00149	0.546
DOC_PP2B_LxvP_1	1187	1190	PF13499	0.619
DOC_PP2B_LxvP_1	1384	1387	PF13499	0.363
DOC_PP2B_LxvP_1	147	150	PF13499	0.391
DOC_PP4_FxxP_1	1323	1326	PF00568	0.793
DOC_PP4_FxxP_1	460	463	PF00568	0.394
DOC_USP7_MATH_1	1234	1238	PF00917	0.758
DOC_USP7_MATH_1	1253	1257	PF00917	0.664
DOC_USP7_MATH_1	1277	1281	PF00917	0.590
DOC_USP7_MATH_1	1293	1297	PF00917	0.760
DOC_USP7_MATH_1	1362	1366	PF00917	0.501
DOC_USP7_MATH_1	238	242	PF00917	0.415
DOC_USP7_MATH_1	317	321	PF00917	0.559
DOC_USP7_MATH_1	370	374	PF00917	0.538
DOC_USP7_MATH_1	375	379	PF00917	0.481
DOC_USP7_MATH_1	416	420	PF00917	0.553
DOC_USP7_MATH_1	437	441	PF00917	0.506
DOC_USP7_MATH_1	592	596	PF00917	0.517
DOC_USP7_MATH_1	722	726	PF00917	0.727
DOC_USP7_MATH_1	729	733	PF00917	0.652
DOC_USP7_MATH_1	782	786	PF00917	0.617
DOC_USP7_MATH_1	796	800	PF00917	0.788
DOC_USP7_MATH_1	824	828	PF00917	0.732
DOC_USP7_MATH_1	831	835	PF00917	0.760
DOC_USP7_MATH_1	840	844	PF00917	0.662
DOC_USP7_MATH_1	94	98	PF00917	0.434
DOC_USP7_UBL2_3	30	34	PF12436	0.551
DOC_USP7_UBL2_3	911	915	PF12436	0.546
DOC_WW_Pin1_4	1134	1139	PF00397	0.546
DOC_WW_Pin1_4	1243	1248	PF00397	0.765
DOC_WW_Pin1_4	1322	1327	PF00397	0.736
DOC_WW_Pin1_4	1351	1356	PF00397	0.472
DOC_WW_Pin1_4	1402	1407	PF00397	0.534
DOC_WW_Pin1_4	1439	1444	PF00397	0.461
DOC_WW_Pin1_4	231	236	PF00397	0.532
DOC_WW_Pin1_4	244	249	PF00397	0.475
DOC_WW_Pin1_4	251	256	PF00397	0.432
DOC_WW_Pin1_4	295	300	PF00397	0.419
DOC_WW_Pin1_4	329	334	PF00397	0.529
DOC_WW_Pin1_4	566	571	PF00397	0.383
DOC_WW_Pin1_4	692	697	PF00397	0.725
DOC_WW_Pin1_4	699	704	PF00397	0.633
DOC_WW_Pin1_4	752	757	PF00397	0.768
DOC_WW_Pin1_4	762	767	PF00397	0.685
DOC_WW_Pin1_4	783	788	PF00397	0.672
DOC_WW_Pin1_4	827	832	PF00397	0.735
DOC_WW_Pin1_4	866	871	PF00397	0.602
LIG_14-3-3_CanoR_1	1179	1188	PF00244	0.530
LIG_14-3-3_CanoR_1	1281	1288	PF00244	0.602
LIG_14-3-3_CanoR_1	1392	1397	PF00244	0.532
LIG_14-3-3_CanoR_1	1400	1406	PF00244	0.544
LIG_14-3-3_CanoR_1	1414	1423	PF00244	0.387
LIG_14-3-3_CanoR_1	1463	1468	PF00244	0.592
LIG_14-3-3_CanoR_1	154	159	PF00244	0.361
LIG_14-3-3_CanoR_1	199	204	PF00244	0.366
LIG_14-3-3_CanoR_1	334	343	PF00244	0.439
LIG_14-3-3_CanoR_1	371	380	PF00244	0.559
LIG_14-3-3_CanoR_1	382	391	PF00244	0.395
LIG_14-3-3_CanoR_1	393	398	PF00244	0.426
LIG_14-3-3_CanoR_1	480	484	PF00244	0.531
LIG_14-3-3_CanoR_1	497	503	PF00244	0.353
LIG_14-3-3_CanoR_1	871	877	PF00244	0.645
LIG_14-3-3_CanoR_1	886	891	PF00244	0.648
LIG_14-3-3_CanoR_1	90	94	PF00244	0.367
LIG_14-3-3_CanoR_1	930	938	PF00244	0.546
LIG_Actin_WH2_2	465	482	PF00022	0.382
LIG_BIR_III_4	123	127	PF00653	0.460
LIG_BIR_III_4	486	490	PF00653	0.464
LIG_BRCT_BRCA1_1	1154	1158	PF00533	0.546
LIG_BRCT_BRCA1_1	187	191	PF00533	0.235
LIG_BRCT_BRCA1_1	235	239	PF00533	0.583
LIG_BRCT_BRCA1_1	62	66	PF00533	0.436
LIG_BRCT_BRCA1_1	646	650	PF00533	0.411
LIG_CtBP_PxDLS_1	183	187	PF00389	0.234
LIG_deltaCOP1_diTrp_1	1049	1057	PF00928	0.546
LIG_deltaCOP1_diTrp_1	860	868	PF00928	0.708
LIG_DLG_GKlike_1	1377	1384	PF00625	0.429
LIG_DLG_GKlike_1	886	894	PF00625	0.712
LIG_eIF4E_1	1002	1008	PF01652	0.563
LIG_FHA_1	128	134	PF00498	0.486
LIG_FHA_1	1281	1287	PF00498	0.607
LIG_FHA_1	1439	1445	PF00498	0.410
LIG_FHA_1	200	206	PF00498	0.415
LIG_FHA_1	211	217	PF00498	0.376
LIG_FHA_1	38	44	PF00498	0.478
LIG_FHA_1	416	422	PF00498	0.488
LIG_FHA_1	441	447	PF00498	0.502
LIG_FHA_1	542	548	PF00498	0.507
LIG_FHA_1	567	573	PF00498	0.392
LIG_FHA_1	603	609	PF00498	0.478
LIG_FHA_1	684	690	PF00498	0.723
LIG_FHA_1	713	719	PF00498	0.706
LIG_FHA_1	728	734	PF00498	0.669
LIG_FHA_1	851	857	PF00498	0.721
LIG_FHA_2	1018	1024	PF00498	0.545
LIG_FHA_2	1044	1050	PF00498	0.546
LIG_FHA_2	1144	1150	PF00498	0.526
LIG_FHA_2	1171	1177	PF00498	0.546
LIG_FHA_2	1246	1252	PF00498	0.750
LIG_FHA_2	323	329	PF00498	0.526
LIG_FHA_2	541	547	PF00498	0.352
LIG_FHA_2	880	886	PF00498	0.682
LIG_FHA_2	895	901	PF00498	0.572
LIG_Integrin_RGD_1	1377	1379	PF01839	0.625
LIG_Integrin_RGD_1	250	252	PF01839	0.695
LIG_Integrin_RGD_1	488	490	PF01839	0.580
LIG_IRF3_LxIS_1	1412	1418	PF10401	0.371
LIG_LIR_Apic_2	1137	1143	PF02991	0.546
LIG_LIR_Apic_2	1321	1326	PF02991	0.762
LIG_LIR_Apic_2	1435	1440	PF02991	0.477
LIG_LIR_Apic_2	457	463	PF02991	0.386
LIG_LIR_Apic_2	565	570	PF02991	0.378
LIG_LIR_Gen_1	1030	1039	PF02991	0.519
LIG_LIR_Gen_1	1049	1058	PF02991	0.427
LIG_LIR_Gen_1	1170	1178	PF02991	0.546
LIG_LIR_Gen_1	157	167	PF02991	0.367
LIG_LIR_Gen_1	188	198	PF02991	0.297
LIG_LIR_Gen_1	40	50	PF02991	0.494
LIG_LIR_Gen_1	490	498	PF02991	0.309
LIG_LIR_Gen_1	589	596	PF02991	0.507
LIG_LIR_Gen_1	633	644	PF02991	0.359
LIG_LIR_Gen_1	702	711	PF02991	0.660
LIG_LIR_Nem_3	1030	1035	PF02991	0.540
LIG_LIR_Nem_3	1049	1053	PF02991	0.427
LIG_LIR_Nem_3	1055	1060	PF02991	0.461
LIG_LIR_Nem_3	11	15	PF02991	0.588
LIG_LIR_Nem_3	1170	1174	PF02991	0.585
LIG_LIR_Nem_3	157	162	PF02991	0.362
LIG_LIR_Nem_3	166	170	PF02991	0.373
LIG_LIR_Nem_3	188	194	PF02991	0.301
LIG_LIR_Nem_3	40	45	PF02991	0.494
LIG_LIR_Nem_3	467	472	PF02991	0.429
LIG_LIR_Nem_3	490	495	PF02991	0.383
LIG_LIR_Nem_3	573	577	PF02991	0.429
LIG_LIR_Nem_3	589	593	PF02991	0.361
LIG_LIR_Nem_3	633	639	PF02991	0.359
LIG_LIR_Nem_3	702	707	PF02991	0.634
LIG_MAD2	779	787	PF02301	0.576
LIG_MLH1_MIPbox_1	187	191	PF16413	0.235
LIG_Pex14_2	307	311	PF04695	0.491
LIG_Pex14_2	335	339	PF04695	0.521
LIG_Pex14_2	906	910	PF04695	0.605
LIG_Pex14_2	969	973	PF04695	0.507
LIG_PTB_Apo_2	1431	1438	PF02174	0.557
LIG_PTB_Apo_2	350	357	PF02174	0.472
LIG_PTB_Phospho_1	1431	1437	PF10480	0.560
LIG_PTB_Phospho_1	350	356	PF10480	0.468
LIG_Rb_pABgroove_1	338	346	PF01858	0.419
LIG_REV1ctd_RIR_1	1055	1063	PF16727	0.619
LIG_SH2_CRK	1032	1036	PF00017	0.516
LIG_SH2_CRK	1437	1441	PF00017	0.471
LIG_SH2_CRK	274	278	PF00017	0.321
LIG_SH2_CRK	91	95	PF00017	0.437
LIG_SH2_NCK_1	1140	1144	PF00017	0.619
LIG_SH2_PTP2	450	453	PF00017	0.387
LIG_SH2_SRC	107	110	PF00017	0.232
LIG_SH2_SRC	774	777	PF00017	0.711
LIG_SH2_STAP1	1446	1450	PF00017	0.492
LIG_SH2_STAP1	286	290	PF00017	0.401
LIG_SH2_STAP1	936	940	PF00017	0.546
LIG_SH2_STAT3	1065	1068	PF00017	0.619
LIG_SH2_STAT3	560	563	PF00017	0.486
LIG_SH2_STAT5	1041	1044	PF00017	0.507
LIG_SH2_STAT5	107	110	PF00017	0.368
LIG_SH2_STAT5	1075	1078	PF00017	0.546
LIG_SH2_STAT5	1446	1449	PF00017	0.548
LIG_SH2_STAT5	189	192	PF00017	0.369
LIG_SH2_STAT5	211	214	PF00017	0.465
LIG_SH2_STAT5	390	393	PF00017	0.449
LIG_SH2_STAT5	450	453	PF00017	0.387
LIG_SH2_STAT5	91	94	PF00017	0.408
LIG_SH2_STAT5	970	973	PF00017	0.504
LIG_SH3_1	1437	1443	PF00018	0.474
LIG_SH3_1	754	760	PF00018	0.737
LIG_SH3_2	65	70	PF14604	0.398
LIG_SH3_3	1148	1154	PF00018	0.546
LIG_SH3_3	1335	1341	PF00018	0.246
LIG_SH3_3	1437	1443	PF00018	0.492
LIG_SH3_3	1462	1468	PF00018	0.589
LIG_SH3_3	62	68	PF00018	0.377
LIG_SH3_3	728	734	PF00018	0.758
LIG_SH3_3	754	760	PF00018	0.807
LIG_SUMO_SIM_anti_2	96	105	PF11976	0.379
LIG_SUMO_SIM_par_1	1161	1166	PF11976	0.546
LIG_SUMO_SIM_par_1	1228	1233	PF11976	0.711
LIG_SUMO_SIM_par_1	127	132	PF11976	0.405
LIG_SUMO_SIM_par_1	1314	1322	PF11976	0.564
LIG_SUMO_SIM_par_1	847	857	PF11976	0.732
LIG_TRAF2_1	1237	1240	PF00917	0.781
LIG_TRAF2_1	1427	1430	PF00917	0.419
LIG_TRAF2_1	739	742	PF00917	0.796
LIG_TRAF2_1	899	902	PF00917	0.635
LIG_TYR_ITIM	272	277	PF00017	0.322
LIG_UBA3_1	1221	1227	PF00899	0.618
LIG_UBA3_1	905	911	PF00899	0.605
LIG_WRC_WIRS_1	1168	1173	PF05994	0.585
LIG_WRC_WIRS_1	636	641	PF05994	0.411
LIG_WW_3	247	251	PF00397	0.548
LIG_WW_3	655	659	PF00397	0.601
MOD_CDC14_SPxK_1	1325	1328	PF00782	0.583
MOD_CDC14_SPxK_1	247	250	PF00782	0.544
MOD_CDK_SPK_2	295	300	PF00069	0.403
MOD_CDK_SPK_2	329	334	PF00069	0.529
MOD_CDK_SPK_2	866	871	PF00069	0.571
MOD_CDK_SPxK_1	1322	1328	PF00069	0.583
MOD_CDK_SPxK_1	244	250	PF00069	0.542
MOD_CK1_1	1003	1009	PF00069	0.546
MOD_CK1_1	1012	1018	PF00069	0.546
MOD_CK1_1	1280	1286	PF00069	0.608
MOD_CK1_1	1322	1328	PF00069	0.736
MOD_CK1_1	1380	1386	PF00069	0.494
MOD_CK1_1	157	163	PF00069	0.349
MOD_CK1_1	185	191	PF00069	0.320
MOD_CK1_1	242	248	PF00069	0.525
MOD_CK1_1	306	312	PF00069	0.488
MOD_CK1_1	322	328	PF00069	0.450
MOD_CK1_1	329	335	PF00069	0.516
MOD_CK1_1	406	412	PF00069	0.452
MOD_CK1_1	435	441	PF00069	0.528
MOD_CK1_1	525	531	PF00069	0.473
MOD_CK1_1	595	601	PF00069	0.478
MOD_CK1_1	676	682	PF00069	0.735
MOD_CK1_1	712	718	PF00069	0.663
MOD_CK1_1	727	733	PF00069	0.554
MOD_CK1_1	736	742	PF00069	0.709
MOD_CK1_1	807	813	PF00069	0.599
MOD_CK1_1	817	823	PF00069	0.605
MOD_CK1_1	827	833	PF00069	0.641
MOD_CK1_1	83	89	PF00069	0.443
MOD_CK1_1	888	894	PF00069	0.751
MOD_CK2_1	1138	1144	PF00069	0.619
MOD_CK2_1	1170	1176	PF00069	0.546
MOD_CK2_1	1234	1240	PF00069	0.714
MOD_CK2_1	1312	1318	PF00069	0.608
MOD_CK2_1	1346	1352	PF00069	0.690
MOD_CK2_1	1424	1430	PF00069	0.524
MOD_CK2_1	426	432	PF00069	0.404
MOD_CK2_1	562	568	PF00069	0.388
MOD_CK2_1	736	742	PF00069	0.790
MOD_CK2_1	894	900	PF00069	0.765
MOD_Cter_Amidation	28	31	PF01082	0.535
MOD_GlcNHglycan	104	107	PF01048	0.580
MOD_GlcNHglycan	1267	1270	PF01048	0.454
MOD_GlcNHglycan	1272	1276	PF01048	0.476
MOD_GlcNHglycan	1297	1300	PF01048	0.563
MOD_GlcNHglycan	1309	1312	PF01048	0.496
MOD_GlcNHglycan	1360	1363	PF01048	0.724
MOD_GlcNHglycan	1424	1427	PF01048	0.710
MOD_GlcNHglycan	1465	1468	PF01048	0.802
MOD_GlcNHglycan	26	29	PF01048	0.575
MOD_GlcNHglycan	282	285	PF01048	0.435
MOD_GlcNHglycan	31	34	PF01048	0.505
MOD_GlcNHglycan	311	314	PF01048	0.753
MOD_GlcNHglycan	427	431	PF01048	0.730
MOD_GlcNHglycan	453	456	PF01048	0.601
MOD_GlcNHglycan	466	469	PF01048	0.621
MOD_GlcNHglycan	499	502	PF01048	0.633
MOD_GlcNHglycan	535	538	PF01048	0.602
MOD_GlcNHglycan	584	587	PF01048	0.621
MOD_GlcNHglycan	594	597	PF01048	0.576
MOD_GlcNHglycan	605	608	PF01048	0.593
MOD_GlcNHglycan	620	623	PF01048	0.561
MOD_GlcNHglycan	724	727	PF01048	0.379
MOD_GlcNHglycan	82	85	PF01048	0.622
MOD_GlcNHglycan	833	837	PF01048	0.582
MOD_GlcNHglycan	874	877	PF01048	0.450
MOD_GSK3_1	1008	1015	PF00069	0.543
MOD_GSK3_1	1017	1024	PF00069	0.525
MOD_GSK3_1	1134	1141	PF00069	0.547
MOD_GSK3_1	1152	1159	PF00069	0.470
MOD_GSK3_1	1273	1280	PF00069	0.697
MOD_GSK3_1	1302	1309	PF00069	0.691
MOD_GSK3_1	1329	1336	PF00069	0.751
MOD_GSK3_1	1339	1346	PF00069	0.423
MOD_GSK3_1	1358	1365	PF00069	0.458
MOD_GSK3_1	1373	1380	PF00069	0.416
MOD_GSK3_1	165	172	PF00069	0.381
MOD_GSK3_1	238	245	PF00069	0.516
MOD_GSK3_1	250	257	PF00069	0.518
MOD_GSK3_1	280	287	PF00069	0.379
MOD_GSK3_1	302	309	PF00069	0.477
MOD_GSK3_1	318	325	PF00069	0.542
MOD_GSK3_1	371	378	PF00069	0.456
MOD_GSK3_1	380	387	PF00069	0.475
MOD_GSK3_1	389	396	PF00069	0.418
MOD_GSK3_1	411	418	PF00069	0.461
MOD_GSK3_1	431	438	PF00069	0.383
MOD_GSK3_1	518	525	PF00069	0.487
MOD_GSK3_1	52	59	PF00069	0.417
MOD_GSK3_1	529	536	PF00069	0.384
MOD_GSK3_1	562	569	PF00069	0.403
MOD_GSK3_1	582	589	PF00069	0.245
MOD_GSK3_1	592	599	PF00069	0.376
MOD_GSK3_1	603	610	PF00069	0.376
MOD_GSK3_1	673	680	PF00069	0.750
MOD_GSK3_1	720	727	PF00069	0.722
MOD_GSK3_1	729	736	PF00069	0.639
MOD_GSK3_1	752	759	PF00069	0.807
MOD_GSK3_1	76	83	PF00069	0.442
MOD_GSK3_1	782	789	PF00069	0.708
MOD_GSK3_1	792	799	PF00069	0.697
MOD_GSK3_1	803	810	PF00069	0.758
MOD_GSK3_1	813	820	PF00069	0.775
MOD_GSK3_1	827	834	PF00069	0.752
MOD_GSK3_1	840	847	PF00069	0.635
MOD_GSK3_1	881	888	PF00069	0.717
MOD_GSK3_1	89	96	PF00069	0.323
MOD_GSK3_1	890	897	PF00069	0.699
MOD_GSK3_1	996	1003	PF00069	0.545
MOD_LATS_1	1398	1404	PF00433	0.624
MOD_N-GLC_1	192	197	PF02516	0.560
MOD_N-GLC_1	242	247	PF02516	0.753
MOD_N-GLC_1	400	405	PF02516	0.637
MOD_N-GLC_1	440	445	PF02516	0.649
MOD_N-GLC_1	845	850	PF02516	0.557
MOD_NEK2_1	1007	1012	PF00069	0.484
MOD_NEK2_1	1167	1172	PF00069	0.546
MOD_NEK2_1	1203	1208	PF00069	0.580
MOD_NEK2_1	1288	1293	PF00069	0.721
MOD_NEK2_1	1307	1312	PF00069	0.575
MOD_NEK2_1	1356	1361	PF00069	0.521
MOD_NEK2_1	165	170	PF00069	0.238
MOD_NEK2_1	192	197	PF00069	0.360
MOD_NEK2_1	221	226	PF00069	0.517
MOD_NEK2_1	239	244	PF00069	0.526
MOD_NEK2_1	400	405	PF00069	0.319
MOD_NEK2_1	618	623	PF00069	0.479
MOD_NEK2_1	644	649	PF00069	0.411
MOD_NEK2_1	803	808	PF00069	0.697
MOD_NEK2_1	879	884	PF00069	0.655
MOD_NEK2_1	89	94	PF00069	0.370
MOD_NEK2_1	995	1000	PF00069	0.563
MOD_NEK2_2	635	640	PF00069	0.411
MOD_NEK2_2	920	925	PF00069	0.619
MOD_PIKK_1	233	239	PF00454	0.578
MOD_PIKK_1	290	296	PF00454	0.417
MOD_PIKK_1	334	340	PF00454	0.521
MOD_PIKK_1	382	388	PF00454	0.448
MOD_PIKK_1	56	62	PF00454	0.549
MOD_PIKK_1	673	679	PF00454	0.675
MOD_PIKK_1	683	689	PF00454	0.707
MOD_PIKK_1	890	896	PF00454	0.783
MOD_PK_1	393	399	PF00069	0.447
MOD_PKA_1	1400	1406	PF00069	0.565
MOD_PKA_1	199	205	PF00069	0.368
MOD_PKA_1	24	30	PF00069	0.724
MOD_PKA_1	529	535	PF00069	0.329
MOD_PKA_2	1043	1049	PF00069	0.524
MOD_PKA_2	1280	1286	PF00069	0.652
MOD_PKA_2	1400	1406	PF00069	0.561
MOD_PKA_2	199	205	PF00069	0.368
MOD_PKA_2	24	30	PF00069	0.728
MOD_PKA_2	370	376	PF00069	0.567
MOD_PKA_2	479	485	PF00069	0.476
MOD_PKA_2	496	502	PF00069	0.346
MOD_PKA_2	525	531	PF00069	0.441
MOD_PKA_2	533	539	PF00069	0.371
MOD_PKA_2	673	679	PF00069	0.734
MOD_PKA_2	885	891	PF00069	0.733
MOD_PKA_2	89	95	PF00069	0.369
MOD_PKA_2	929	935	PF00069	0.546
MOD_PKB_1	1177	1185	PF00069	0.530
MOD_PKB_1	1399	1407	PF00069	0.412
MOD_Plk_1	1003	1009	PF00069	0.525
MOD_Plk_1	1129	1135	PF00069	0.526
MOD_Plk_1	1410	1416	PF00069	0.377
MOD_Plk_1	1450	1456	PF00069	0.475
MOD_Plk_1	1461	1467	PF00069	0.508
MOD_Plk_1	192	198	PF00069	0.359
MOD_Plk_1	284	290	PF00069	0.393
MOD_Plk_1	400	406	PF00069	0.440
MOD_Plk_1	736	742	PF00069	0.783
MOD_Plk_1	74	80	PF00069	0.432
MOD_Plk_1	817	823	PF00069	0.581
MOD_Plk_1	850	856	PF00069	0.726
MOD_Plk_1	879	885	PF00069	0.669
MOD_Plk_1	995	1001	PF00069	0.568
MOD_Plk_2-3	541	547	PF00069	0.505
MOD_Plk_2-3	709	715	PF00069	0.698
MOD_Plk_2-3	850	856	PF00069	0.653
MOD_Plk_4	1003	1009	PF00069	0.568
MOD_Plk_4	1203	1209	PF00069	0.619
MOD_Plk_4	1312	1318	PF00069	0.608
MOD_Plk_4	1451	1457	PF00069	0.508
MOD_Plk_4	154	160	PF00069	0.361
MOD_Plk_4	193	199	PF00069	0.358
MOD_Plk_4	442	448	PF00069	0.434
MOD_Plk_4	518	524	PF00069	0.405
MOD_Plk_4	562	568	PF00069	0.460
MOD_Plk_4	840	846	PF00069	0.674
MOD_Plk_4	920	926	PF00069	0.546
MOD_ProDKin_1	1134	1140	PF00069	0.546
MOD_ProDKin_1	1243	1249	PF00069	0.764
MOD_ProDKin_1	1322	1328	PF00069	0.736
MOD_ProDKin_1	1351	1357	PF00069	0.472
MOD_ProDKin_1	1402	1408	PF00069	0.532
MOD_ProDKin_1	1439	1445	PF00069	0.461
MOD_ProDKin_1	231	237	PF00069	0.534
MOD_ProDKin_1	244	250	PF00069	0.477
MOD_ProDKin_1	251	257	PF00069	0.429
MOD_ProDKin_1	295	301	PF00069	0.421
MOD_ProDKin_1	329	335	PF00069	0.526
MOD_ProDKin_1	566	572	PF00069	0.385
MOD_ProDKin_1	692	698	PF00069	0.720
MOD_ProDKin_1	699	705	PF00069	0.633
MOD_ProDKin_1	752	758	PF00069	0.768
MOD_ProDKin_1	762	768	PF00069	0.681
MOD_ProDKin_1	783	789	PF00069	0.672
MOD_ProDKin_1	827	833	PF00069	0.734
MOD_ProDKin_1	866	872	PF00069	0.602
MOD_SUMO_for_1	772	775	PF00179	0.555
MOD_SUMO_rev_2	1080	1089	PF00179	0.546
MOD_SUMO_rev_2	1325	1332	PF00179	0.731
MOD_SUMO_rev_2	361	369	PF00179	0.380
MOD_SUMO_rev_2	474	479	PF00179	0.306
MOD_SUMO_rev_2	900	906	PF00179	0.646
TRG_DiLeu_BaEn_3	775	781	PF01217	0.703
TRG_DiLeu_BaEn_4	1239	1245	PF01217	0.613
TRG_DiLeu_BaEn_4	474	480	PF01217	0.462
TRG_DiLeu_BaLyEn_6	572	577	PF01217	0.355
TRG_DiLeu_BaLyEn_6	611	616	PF01217	0.348
TRG_DiLeu_LyEn_5	264	269	PF01217	0.472
TRG_ENDOCYTIC_2	1032	1035	PF00928	0.516
TRG_ENDOCYTIC_2	167	170	PF00928	0.376
TRG_ENDOCYTIC_2	189	192	PF00928	0.369
TRG_ENDOCYTIC_2	274	277	PF00928	0.347
TRG_ENDOCYTIC_2	450	453	PF00928	0.387
TRG_ER_diArg_1	1051	1054	PF00400	0.546
TRG_ER_diArg_1	1177	1180	PF00400	0.530
TRG_ER_diArg_1	1399	1401	PF00400	0.555
TRG_ER_diArg_1	19	21	PF00400	0.641
TRG_ER_diArg_1	198	200	PF00400	0.356
TRG_ER_diArg_1	24	26	PF00400	0.746
TRG_ER_diArg_1	356	358	PF00400	0.502
TRG_Pf-PMV_PEXEL_1	1179	1183	PF00026	0.330
TRG_Pf-PMV_PEXEL_1	1219	1224	PF00026	0.349
TRG_Pf-PMV_PEXEL_1	1458	1462	PF00026	0.667
TRG_Pf-PMV_PEXEL_1	770	775	PF00026	0.438

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I8U7	Leptomonas seymouri	48%	99%
A0A3S5H7W8	Leishmania donovani	85%	100%
A4HAS7	Leishmania braziliensis	69%	100%
A4I9Y7	Leishmania infantum	86%	100%
Q4Q2Y5	Leishmania major	86%	100%