ATP-dependent RNA helicase

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

ATP-dependent RNA helicase, putative

Species:

Leishmania mexicana

UniProt:

E9B4Z0_LEIMU

TriTrypDb:

LmxM.33.2050

Length:

804

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

Cellular components
Term	Name	Level	Count
GO:0005730	nucleolus	5	12
GO:0043226	organelle	2	12
GO:0043228	non-membrane-bounded organelle	3	12
GO:0043229	intracellular organelle	3	12
GO:0043232	intracellular non-membrane-bounded organelle	4	12
GO:0110165	cellular anatomical entity	1	12

Expansion

Sequence features

E9B4Z0

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B4Z0

Function

Biological processes
Term	Name	Level	Count
GO:0006139	nucleobase-containing compound metabolic process	3	1
GO:0006364	rRNA processing	8	1
GO:0006396	RNA processing	6	1
GO:0006725	cellular aromatic compound metabolic process	3	1
GO:0006807	nitrogen compound metabolic process	2	1
GO:0008152	metabolic process	1	1
GO:0009987	cellular process	1	1
GO:0016070	RNA metabolic process	5	1
GO:0016072	rRNA metabolic process	7	1
GO:0034470	ncRNA processing	7	1
GO:0034641	cellular nitrogen compound metabolic process	3	1
GO:0034660	ncRNA metabolic process	6	1
GO:0043170	macromolecule metabolic process	3	1
GO:0044237	cellular metabolic process	2	1
GO:0044238	primary metabolic process	2	1
GO:0046483	heterocycle metabolic process	3	1
GO:0071704	organic substance metabolic process	2	1
GO:0090304	nucleic acid metabolic process	4	1
GO:1901360	organic cyclic compound metabolic process	3	1

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	12
GO:0003676	nucleic acid binding	3	12
GO:0003723	RNA binding	4	12
GO:0003724	RNA helicase activity	3	12
GO:0003743	translation initiation factor activity	4	11
GO:0003824	catalytic activity	1	12
GO:0004386	helicase activity	2	12
GO:0005488	binding	1	12
GO:0005524	ATP binding	5	12
GO:0008135	translation factor activity, RNA binding	3	11
GO:0008186	ATP-dependent activity, acting on RNA	2	12
GO:0016462	pyrophosphatase activity	5	11
GO:0016787	hydrolase activity	2	12
GO:0016817	hydrolase activity, acting on acid anhydrides	3	11
GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	4	11
GO:0016887	ATP hydrolysis activity	7	11
GO:0017076	purine nucleotide binding	4	12
GO:0017111	ribonucleoside triphosphate phosphatase activity	6	11
GO:0030554	adenyl nucleotide binding	5	12
GO:0032553	ribonucleotide binding	3	12
GO:0032555	purine ribonucleotide binding	4	12
GO:0032559	adenyl ribonucleotide binding	5	12
GO:0035639	purine ribonucleoside triphosphate binding	4	12
GO:0036094	small molecule binding	2	12
GO:0043167	ion binding	2	12
GO:0043168	anion binding	3	12
GO:0045182	translation regulator activity	1	11
GO:0090079	translation regulator activity, nucleic acid binding	2	11
GO:0097159	organic cyclic compound binding	2	12
GO:0097367	carbohydrate derivative binding	2	12
GO:0140098	catalytic activity, acting on RNA	3	12
GO:0140640	catalytic activity, acting on a nucleic acid	2	12
GO:0140657	ATP-dependent activity	1	12
GO:1901265	nucleoside phosphate binding	3	12
GO:1901363	heterocyclic compound binding	2	12

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	13	17	PF00656	0.576
CLV_C14_Caspase3-7	630	634	PF00656	0.526
CLV_C14_Caspase3-7	731	735	PF00656	0.445
CLV_NRD_NRD_1	309	311	PF00675	0.202
CLV_NRD_NRD_1	465	467	PF00675	0.508
CLV_NRD_NRD_1	49	51	PF00675	0.237
CLV_NRD_NRD_1	567	569	PF00675	0.506
CLV_NRD_NRD_1	620	622	PF00675	0.617
CLV_NRD_NRD_1	756	758	PF00675	0.569
CLV_NRD_NRD_1	778	780	PF00675	0.545
CLV_NRD_NRD_1	789	791	PF00675	0.464
CLV_PCSK_FUR_1	567	571	PF00082	0.515
CLV_PCSK_KEX2_1	258	260	PF00082	0.305
CLV_PCSK_KEX2_1	309	311	PF00082	0.202
CLV_PCSK_KEX2_1	318	320	PF00082	0.202
CLV_PCSK_KEX2_1	427	429	PF00082	0.335
CLV_PCSK_KEX2_1	500	502	PF00082	0.412
CLV_PCSK_KEX2_1	567	569	PF00082	0.497
CLV_PCSK_KEX2_1	620	622	PF00082	0.553
CLV_PCSK_KEX2_1	718	720	PF00082	0.620
CLV_PCSK_KEX2_1	760	762	PF00082	0.568
CLV_PCSK_KEX2_1	778	780	PF00082	0.407
CLV_PCSK_PC1ET2_1	258	260	PF00082	0.248
CLV_PCSK_PC1ET2_1	318	320	PF00082	0.226
CLV_PCSK_PC1ET2_1	427	429	PF00082	0.480
CLV_PCSK_PC1ET2_1	500	502	PF00082	0.412
CLV_PCSK_PC1ET2_1	569	571	PF00082	0.505
CLV_PCSK_PC1ET2_1	718	720	PF00082	0.606
CLV_PCSK_PC1ET2_1	760	762	PF00082	0.671
CLV_PCSK_PC7_1	314	320	PF00082	0.269
CLV_PCSK_PC7_1	496	502	PF00082	0.415
CLV_PCSK_PC7_1	563	569	PF00082	0.491
CLV_PCSK_SKI1_1	200	204	PF00082	0.202
CLV_PCSK_SKI1_1	258	262	PF00082	0.301
CLV_PCSK_SKI1_1	31	35	PF00082	0.361
CLV_PCSK_SKI1_1	500	504	PF00082	0.398
CLV_PCSK_SKI1_1	505	509	PF00082	0.435
CLV_PCSK_SKI1_1	632	636	PF00082	0.528
CLV_PCSK_SKI1_1	650	654	PF00082	0.236
CLV_PCSK_SKI1_1	671	675	PF00082	0.253
CLV_PCSK_SKI1_1	718	722	PF00082	0.612
DEG_APCC_DBOX_1	473	481	PF00400	0.427
DEG_SPOP_SBC_1	574	578	PF00917	0.555
DOC_CKS1_1	147	152	PF01111	0.398
DOC_CKS1_1	44	49	PF01111	0.280
DOC_CYCLIN_RxL_1	197	206	PF00134	0.402
DOC_CYCLIN_RxL_1	28	35	PF00134	0.473
DOC_CYCLIN_RxL_1	329	340	PF00134	0.426
DOC_CYCLIN_RxL_1	500	513	PF00134	0.568
DOC_CYCLIN_RxL_1	549	558	PF00134	0.457
DOC_CYCLIN_yClb5_NLxxxL_5	24	33	PF00134	0.350
DOC_CYCLIN_yCln2_LP_2	219	225	PF00134	0.326
DOC_MAPK_FxFP_2	345	348	PF00069	0.426
DOC_MAPK_gen_1	318	326	PF00069	0.402
DOC_MAPK_gen_1	489	497	PF00069	0.465
DOC_MAPK_gen_1	500	509	PF00069	0.438
DOC_MAPK_gen_1	657	667	PF00069	0.250
DOC_MAPK_gen_1	696	705	PF00069	0.399
DOC_MAPK_JIP1_4	503	509	PF00069	0.576
DOC_MAPK_MEF2A_6	249	257	PF00069	0.277
DOC_MAPK_MEF2A_6	503	511	PF00069	0.575
DOC_MAPK_RevD_3	703	719	PF00069	0.548
DOC_PP1_RVXF_1	550	557	PF00149	0.603
DOC_PP2B_LxvP_1	334	337	PF13499	0.402
DOC_PP2B_PxIxI_1	142	148	PF00149	0.332
DOC_PP4_FxxP_1	345	348	PF00568	0.426
DOC_PP4_FxxP_1	42	45	PF00568	0.433
DOC_PP4_FxxP_1	76	79	PF00568	0.409
DOC_USP7_MATH_1	10	14	PF00917	0.596
DOC_USP7_MATH_1	312	316	PF00917	0.507
DOC_USP7_MATH_1	364	368	PF00917	0.511
DOC_USP7_MATH_1	392	396	PF00917	0.500
DOC_USP7_MATH_1	724	728	PF00917	0.660
DOC_USP7_UBL2_3	696	700	PF12436	0.330
DOC_USP7_UBL2_3	760	764	PF12436	0.641
DOC_USP7_UBL2_3	800	804	PF12436	0.640
DOC_USP7_UBL2_3	85	89	PF12436	0.409
DOC_WW_Pin1_4	146	151	PF00397	0.398
DOC_WW_Pin1_4	43	48	PF00397	0.383
DOC_WW_Pin1_4	472	477	PF00397	0.392
DOC_WW_Pin1_4	96	101	PF00397	0.409
LIG_14-3-3_CanoR_1	200	210	PF00244	0.414
LIG_14-3-3_CanoR_1	391	397	PF00244	0.465
LIG_Actin_WH2_2	224	240	PF00022	0.359
LIG_Actin_WH2_2	660	677	PF00022	0.276
LIG_BRCT_BRCA1_1	345	349	PF00533	0.469
LIG_CaM_IQ_9	440	456	PF13499	0.276
LIG_Clathr_ClatBox_1	274	278	PF01394	0.383
LIG_DLG_GKlike_1	102	109	PF00625	0.409
LIG_FHA_1	295	301	PF00498	0.503
LIG_FHA_1	99	105	PF00498	0.424
LIG_FHA_2	373	379	PF00498	0.298
LIG_FHA_2	403	409	PF00498	0.397
LIG_FHA_2	640	646	PF00498	0.381
LIG_FXI_DFP_1	376	380	PF00024	0.332
LIG_GBD_Chelix_1	223	231	PF00786	0.386
LIG_LIR_Apic_2	73	79	PF02991	0.398
LIG_LIR_Gen_1	120	127	PF02991	0.414
LIG_LIR_Gen_1	133	143	PF02991	0.398
LIG_LIR_Gen_1	284	293	PF02991	0.426
LIG_LIR_Gen_1	369	379	PF02991	0.301
LIG_LIR_Gen_1	506	515	PF02991	0.556
LIG_LIR_Gen_1	612	622	PF02991	0.608
LIG_LIR_Gen_1	738	747	PF02991	0.609
LIG_LIR_Gen_1	770	777	PF02991	0.489
LIG_LIR_Nem_3	120	126	PF02991	0.414
LIG_LIR_Nem_3	133	139	PF02991	0.398
LIG_LIR_Nem_3	375	379	PF02991	0.315
LIG_LIR_Nem_3	408	414	PF02991	0.368
LIG_LIR_Nem_3	506	511	PF02991	0.450
LIG_LIR_Nem_3	612	618	PF02991	0.640
LIG_LIR_Nem_3	738	744	PF02991	0.623
LIG_NRBOX	252	258	PF00104	0.251
LIG_Pex14_2	281	285	PF04695	0.492
LIG_Pex14_2	345	349	PF04695	0.469
LIG_PTB_Apo_2	341	348	PF02174	0.402
LIG_PTB_Apo_2	623	630	PF02174	0.665
LIG_PTB_Phospho_1	623	629	PF10480	0.666
LIG_SH2_CRK	411	415	PF00017	0.387
LIG_SH2_PTP2	382	385	PF00017	0.308
LIG_SH2_STAT5	382	385	PF00017	0.290
LIG_SH2_STAT5	662	665	PF00017	0.270
LIG_SH3_3	144	150	PF00018	0.398
LIG_SH3_3	345	351	PF00018	0.426
LIG_SH3_3	41	47	PF00018	0.394
LIG_SH3_3	473	479	PF00018	0.365
LIG_SH3_3	544	550	PF00018	0.507
LIG_SH3_3	587	593	PF00018	0.619
LIG_SH3_3	94	100	PF00018	0.440
LIG_SUMO_SIM_anti_2	320	328	PF11976	0.403
LIG_TRAF2_1	461	464	PF00917	0.420
LIG_TRAF2_1	642	645	PF00917	0.270
LIG_TRAF2_1	770	773	PF00917	0.508
LIG_UBA3_1	253	258	PF00899	0.251
LIG_UBA3_1	33	39	PF00899	0.446
LIG_UBA3_1	507	516	PF00899	0.485
LIG_UBA3_1	77	85	PF00899	0.232
LIG_WRC_WIRS_1	24	29	PF05994	0.392
LIG_WRC_WIRS_1	313	318	PF05994	0.381
LIG_WRC_WIRS_1	373	378	PF05994	0.300
LIG_WRC_WIRS_1	768	773	PF05994	0.514
MOD_CDC14_SPxK_1	99	102	PF00782	0.246
MOD_CDK_SPxK_1	146	152	PF00069	0.232
MOD_CDK_SPxK_1	96	102	PF00069	0.246
MOD_CDK_SPxxK_3	43	50	PF00069	0.246
MOD_CK1_1	294	300	PF00069	0.379
MOD_CK1_1	372	378	PF00069	0.303
MOD_CK1_1	43	49	PF00069	0.299
MOD_CK1_1	576	582	PF00069	0.754
MOD_CK1_1	603	609	PF00069	0.558
MOD_CK1_1	695	701	PF00069	0.277
MOD_CK1_1	70	76	PF00069	0.232
MOD_CK2_1	552	558	PF00069	0.493
MOD_CK2_1	639	645	PF00069	0.291
MOD_CK2_1	724	730	PF00069	0.466
MOD_CK2_1	767	773	PF00069	0.518
MOD_Cter_Amidation	749	752	PF01082	0.535
MOD_Cter_Amidation	755	758	PF01082	0.567
MOD_Cter_Amidation	797	800	PF01082	0.624
MOD_GlcNHglycan	203	206	PF01048	0.258
MOD_GlcNHglycan	215	218	PF01048	0.423
MOD_GlcNHglycan	239	242	PF01048	0.302
MOD_GlcNHglycan	297	300	PF01048	0.286
MOD_GlcNHglycan	366	369	PF01048	0.356
MOD_GlcNHglycan	394	397	PF01048	0.518
MOD_GlcNHglycan	531	534	PF01048	0.597
MOD_GlcNHglycan	605	608	PF01048	0.564
MOD_GlcNHglycan	680	683	PF01048	0.170
MOD_GlcNHglycan	69	72	PF01048	0.232
MOD_GlcNHglycan	794	797	PF01048	0.716
MOD_GSK3_1	10	17	PF00069	0.673
MOD_GSK3_1	158	165	PF00069	0.260
MOD_GSK3_1	291	298	PF00069	0.438
MOD_GSK3_1	525	532	PF00069	0.621
MOD_GSK3_1	575	582	PF00069	0.626
MOD_GSK3_1	632	639	PF00069	0.671
MOD_GSK3_1	98	105	PF00069	0.287
MOD_N-GLC_1	343	348	PF02516	0.236
MOD_N-GLC_1	450	455	PF02516	0.539
MOD_N-GLC_1	678	683	PF02516	0.163
MOD_NEK2_1	138	143	PF00069	0.265
MOD_NEK2_1	162	167	PF00069	0.286
MOD_NEK2_1	203	208	PF00069	0.236
MOD_NEK2_1	237	242	PF00069	0.298
MOD_NEK2_1	276	281	PF00069	0.236
MOD_NEK2_1	288	293	PF00069	0.236
MOD_NEK2_1	450	455	PF00069	0.409
MOD_NEK2_1	485	490	PF00069	0.460
MOD_NEK2_1	529	534	PF00069	0.587
MOD_NEK2_1	65	70	PF00069	0.244
MOD_NEK2_1	653	658	PF00069	0.402
MOD_NEK2_1	80	85	PF00069	0.347
MOD_NEK2_2	627	632	PF00069	0.585
MOD_PIKK_1	724	730	PF00454	0.543
MOD_PK_1	319	325	PF00069	0.272
MOD_PKA_1	318	324	PF00069	0.236
MOD_PKA_1	455	461	PF00069	0.422
MOD_PKA_1	620	626	PF00069	0.534
MOD_PKA_2	318	324	PF00069	0.251
MOD_PKA_2	620	626	PF00069	0.564
MOD_Plk_1	102	108	PF00069	0.246
MOD_Plk_1	158	164	PF00069	0.245
MOD_Plk_1	319	325	PF00069	0.336
MOD_Plk_1	343	349	PF00069	0.236
MOD_Plk_1	600	606	PF00069	0.571
MOD_Plk_1	632	638	PF00069	0.532
MOD_Plk_1	783	789	PF00069	0.583
MOD_Plk_4	206	212	PF00069	0.236
MOD_Plk_4	319	325	PF00069	0.271
MOD_Plk_4	369	375	PF00069	0.286
MOD_ProDKin_1	146	152	PF00069	0.232
MOD_ProDKin_1	43	49	PF00069	0.280
MOD_ProDKin_1	472	478	PF00069	0.383
MOD_ProDKin_1	96	102	PF00069	0.246
MOD_SUMO_for_1	317	320	PF00179	0.381
MOD_SUMO_for_1	677	680	PF00179	0.236
MOD_SUMO_rev_2	228	234	PF00179	0.413
MOD_SUMO_rev_2	493	502	PF00179	0.409
TRG_DiLeu_BaEn_1	710	715	PF01217	0.549
TRG_DiLeu_BaEn_1	784	789	PF01217	0.418
TRG_DiLeu_BaEn_4	416	422	PF01217	0.347
TRG_DiLeu_BaLyEn_6	149	154	PF01217	0.246
TRG_DiLeu_BaLyEn_6	29	34	PF01217	0.372
TRG_DiLeu_BaLyEn_6	334	339	PF01217	0.236
TRG_DiLeu_LyEn_5	784	789	PF01217	0.357
TRG_ENDOCYTIC_2	371	374	PF00928	0.268
TRG_ENDOCYTIC_2	382	385	PF00928	0.274
TRG_ENDOCYTIC_2	411	414	PF00928	0.328
TRG_ENDOCYTIC_2	662	665	PF00928	0.270
TRG_ER_diArg_1	309	311	PF00400	0.330
TRG_ER_diArg_1	567	570	PF00400	0.518
TRG_ER_diArg_1	777	779	PF00400	0.650
TRG_ER_diLys_1	799	804	PF00400	0.595
TRG_NES_CRM1_1	272	284	PF08389	0.241
TRG_NLS_Bipartite_1	778	795	PF00514	0.435
TRG_NLS_MonoCore_2	798	803	PF00514	0.433
TRG_NLS_MonoExtC_3	499	504	PF00514	0.542
TRG_NLS_MonoExtC_3	656	661	PF00514	0.227
TRG_NLS_MonoExtC_3	756	761	PF00514	0.564
TRG_NLS_MonoExtC_3	789	794	PF00514	0.517
TRG_NLS_MonoExtC_3	799	804	PF00514	0.617
TRG_NLS_MonoExtN_4	452	458	PF00514	0.405
TRG_NLS_MonoExtN_4	657	662	PF00514	0.227
TRG_NLS_MonoExtN_4	716	722	PF00514	0.601
TRG_NLS_MonoExtN_4	754	761	PF00514	0.564
TRG_NLS_MonoExtN_4	787	794	PF00514	0.433
TRG_NLS_MonoExtN_4	799	804	PF00514	0.486
TRG_Pf-PMV_PEXEL_1	102	107	PF00026	0.232
TRG_Pf-PMV_PEXEL_1	168	173	PF00026	0.309
TRG_Pf-PMV_PEXEL_1	427	431	PF00026	0.426

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PE92	Leptomonas seymouri	85%	99%
A0A0S4JD47	Bodo saltans	59%	98%
A0A1X0P9U0	Trypanosomatidae	66%	97%
A0A3Q8ID91	Leishmania donovani	33%	100%
A0A3Q8IQY6	Leishmania donovani	34%	100%
A0A3R7NR45	Trypanosoma rangeli	67%	98%
A0A3S5H7C7	Leishmania donovani	24%	100%
A0A3S7X7Z2	Leishmania donovani	96%	100%
A1CTZ6	Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1 / QM 1276 / 107)	34%	86%
A1DNG2	Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181)	33%	86%
A2QRY2	Aspergillus niger (strain CBS 513.88 / FGSC A1513)	34%	86%
A2YV85	Oryza sativa subsp. indica	37%	94%
A3BT52	Oryza sativa subsp. japonica	37%	94%
A3LZT3	Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545)	32%	86%
A4HAR7	Leishmania braziliensis	89%	100%
A4HGR1	Leishmania braziliensis	33%	100%
A4I3T6	Leishmania infantum	33%	100%
A4I9Y2	Leishmania infantum	96%	100%
A4IDI7	Leishmania infantum	34%	100%
A4R5B8	Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)	35%	88%
A5DLR3	Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324)	32%	88%
A5DZT7	Lodderomyces elongisporus (strain ATCC 11503 / CBS 2605 / JCM 1781 / NBRC 1676 / NRRL YB-4239)	30%	85%
A6QUM7	Ajellomyces capsulatus (strain NAm1 / WU24)	36%	89%
A6ZXU0	Saccharomyces cerevisiae (strain YJM789)	31%	81%
A7TGW7	Vanderwaltozyma polyspora (strain ATCC 22028 / DSM 70294 / BCRC 21397 / CBS 2163 / NBRC 10782 / NRRL Y-8283 / UCD 57-17)	31%	82%
C9ZMQ4	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	65%	95%
E9AH36	Leishmania infantum	24%	100%
E9ASZ0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	34%	100%
E9AWL4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	23%	100%
E9B028	Leishmania mexicana (strain MHOM/GT/2001/U1103)	32%	100%
O49289	Arabidopsis thaliana	37%	95%
P0CR06	Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565)	33%	100%
P0CR07	Cryptococcus neoformans var. neoformans serotype D (strain B-3501A)	33%	100%
Q09719	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	35%	95%
Q0CMM8	Aspergillus terreus (strain NIH 2624 / FGSC A1156)	34%	87%
Q0UMB6	Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173)	32%	92%
Q12389	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	31%	81%
Q4HZ42	Gibberella zeae (strain ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1)	35%	90%
Q4Q1K8	Leishmania major	34%	100%
Q4Q2Z6	Leishmania major	95%	100%
Q4Q858	Leishmania major	33%	100%
Q4QAV6	Leishmania major	24%	100%
Q5ANB2	Candida albicans (strain SC5314 / ATCC MYA-2876)	30%	89%
Q5BFU7	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	34%	86%
Q6BL34	Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968)	31%	86%
Q6C7X8	Yarrowia lipolytica (strain CLIB 122 / E 150)	31%	87%
Q6CIR0	Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)	31%	83%
Q6FNA2	Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)	33%	83%
Q757U8	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)	33%	84%
Q8K4L0	Mus musculus	38%	92%
Q8NJM2	Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)	33%	93%
Q8TDD1	Homo sapiens	39%	91%
V5DJX8	Trypanosoma cruzi	70%	100%