LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania mexicana
UniProt:
E9B4Y6_LEIMU
TriTrypDb:
LmxM.33.2010
Length:
165

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 6
NetGPI no yes: 0, no: 6
Cellular components
TermNameLevelCount
GO:0005635 nuclear envelope 4 1
GO:0005783 endoplasmic reticulum 5 1
GO:0016020 membrane 2 4
GO:0031967 organelle envelope 3 1
GO:0031975 envelope 2 1
GO:0043226 organelle 2 1
GO:0043227 membrane-bounded organelle 3 1
GO:0043229 intracellular organelle 3 1
GO:0043231 intracellular membrane-bounded organelle 4 1
GO:0110165 cellular anatomical entity 1 4
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Expansion

Sequence features

E9B4Y6
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B4Y6

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_NRD_NRD_1 90 92 PF00675 0.448
CLV_PCSK_KEX2_1 90 92 PF00082 0.449
CLV_PCSK_SKI1_1 153 157 PF00082 0.650
CLV_PCSK_SKI1_1 37 41 PF00082 0.587
CLV_PCSK_SKI1_1 84 88 PF00082 0.495
DEG_Nend_Nbox_1 1 3 PF02207 0.689
DOC_PP1_RVXF_1 126 133 PF00149 0.546
DOC_USP7_MATH_1 45 49 PF00917 0.768
DOC_WW_Pin1_4 158 163 PF00397 0.506
LIG_14-3-3_CanoR_1 91 100 PF00244 0.695
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N0P996 Leptomonas seymouri 57% 100%
A0A3Q8INA7 Leishmania donovani 77% 100%
A4HAR4 Leishmania braziliensis 66% 98%
A4I9X8 Leishmania infantum 77% 100%
Q4Q300 Leishmania major 76% 100%
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Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS