LeishMANIAdb
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Proteophosphoglycan ppg4

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Proteophosphoglycan ppg4
Gene product:
hypothetical protein, conserved
Species:
Leishmania mexicana
UniProt:
E9B4X3_LEIMU
TriTrypDb:
LmxM.33.1480
Length:
999

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 5
NetGPI no yes: 0, no: 5
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B4X3
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B4X3

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 389 393 PF00656 0.614
CLV_C14_Caspase3-7 473 477 PF00656 0.575
CLV_C14_Caspase3-7 491 495 PF00656 0.629
CLV_C14_Caspase3-7 765 769 PF00656 0.699
CLV_C14_Caspase3-7 79 83 PF00656 0.549
CLV_C14_Caspase3-7 982 986 PF00656 0.537
CLV_NRD_NRD_1 145 147 PF00675 0.545
CLV_NRD_NRD_1 440 442 PF00675 0.606
CLV_NRD_NRD_1 470 472 PF00675 0.644
CLV_NRD_NRD_1 499 501 PF00675 0.539
CLV_NRD_NRD_1 522 524 PF00675 0.683
CLV_NRD_NRD_1 574 576 PF00675 0.603
CLV_NRD_NRD_1 667 669 PF00675 0.666
CLV_NRD_NRD_1 68 70 PF00675 0.674
CLV_NRD_NRD_1 820 822 PF00675 0.718
CLV_NRD_NRD_1 831 833 PF00675 0.624
CLV_NRD_NRD_1 845 847 PF00675 0.582
CLV_NRD_NRD_1 862 864 PF00675 0.525
CLV_NRD_NRD_1 9 11 PF00675 0.692
CLV_NRD_NRD_1 972 974 PF00675 0.567
CLV_PCSK_FUR_1 487 491 PF00082 0.545
CLV_PCSK_FUR_1 818 822 PF00082 0.597
CLV_PCSK_FUR_1 970 974 PF00082 0.567
CLV_PCSK_KEX2_1 303 305 PF00082 0.854
CLV_PCSK_KEX2_1 440 442 PF00082 0.606
CLV_PCSK_KEX2_1 470 472 PF00082 0.644
CLV_PCSK_KEX2_1 489 491 PF00082 0.604
CLV_PCSK_KEX2_1 499 501 PF00082 0.551
CLV_PCSK_KEX2_1 522 524 PF00082 0.683
CLV_PCSK_KEX2_1 574 576 PF00082 0.651
CLV_PCSK_KEX2_1 820 822 PF00082 0.735
CLV_PCSK_KEX2_1 845 847 PF00082 0.711
CLV_PCSK_KEX2_1 970 972 PF00082 0.569
CLV_PCSK_PC1ET2_1 303 305 PF00082 0.552
CLV_PCSK_PC1ET2_1 489 491 PF00082 0.621
CLV_PCSK_SKI1_1 398 402 PF00082 0.659
CLV_PCSK_SKI1_1 499 503 PF00082 0.534
CLV_PCSK_SKI1_1 547 551 PF00082 0.698
CLV_PCSK_SKI1_1 701 705 PF00082 0.629
CLV_PCSK_SKI1_1 81 85 PF00082 0.686
CLV_PCSK_SKI1_1 994 998 PF00082 0.601
DEG_APCC_DBOX_1 546 554 PF00400 0.650
DEG_APCC_DBOX_1 655 663 PF00400 0.633
DEG_APCC_DBOX_1 696 704 PF00400 0.629
DEG_APCC_DBOX_1 970 978 PF00400 0.527
DEG_COP1_1 235 243 PF00400 0.592
DEG_Kelch_actinfilin_1 12 16 PF01344 0.661
DEG_SCF_FBW7_1 648 655 PF00400 0.503
DEG_SCF_FBW7_1 946 952 PF00400 0.494
DEG_SPOP_SBC_1 251 255 PF00917 0.713
DEG_SPOP_SBC_1 557 561 PF00917 0.510
DEG_SPOP_SBC_1 949 953 PF00917 0.479
DOC_CKS1_1 946 951 PF01111 0.495
DOC_CYCLIN_RxL_1 366 380 PF00134 0.702
DOC_MAPK_gen_1 10 17 PF00069 0.699
DOC_MAPK_gen_1 395 404 PF00069 0.522
DOC_MAPK_gen_1 863 870 PF00069 0.513
DOC_MAPK_MEF2A_6 10 17 PF00069 0.663
DOC_MAPK_MEF2A_6 863 870 PF00069 0.513
DOC_PP1_RVXF_1 277 283 PF00149 0.656
DOC_PP1_RVXF_1 370 377 PF00149 0.699
DOC_PP1_RVXF_1 399 405 PF00149 0.527
DOC_PP2B_LxvP_1 432 435 PF13499 0.571
DOC_PP4_FxxP_1 992 995 PF00568 0.426
DOC_USP7_MATH_1 145 149 PF00917 0.646
DOC_USP7_MATH_1 183 187 PF00917 0.655
DOC_USP7_MATH_1 233 237 PF00917 0.616
DOC_USP7_MATH_1 251 255 PF00917 0.678
DOC_USP7_MATH_1 411 415 PF00917 0.651
DOC_USP7_MATH_1 436 440 PF00917 0.814
DOC_USP7_MATH_1 555 559 PF00917 0.680
DOC_USP7_MATH_1 636 640 PF00917 0.589
DOC_USP7_MATH_1 680 684 PF00917 0.565
DOC_USP7_MATH_1 757 761 PF00917 0.704
DOC_USP7_MATH_1 83 87 PF00917 0.612
DOC_USP7_MATH_1 949 953 PF00917 0.479
DOC_USP7_UBL2_3 735 739 PF12436 0.649
DOC_WW_Pin1_4 108 113 PF00397 0.558
DOC_WW_Pin1_4 115 120 PF00397 0.594
DOC_WW_Pin1_4 128 133 PF00397 0.485
DOC_WW_Pin1_4 162 167 PF00397 0.716
DOC_WW_Pin1_4 221 226 PF00397 0.747
DOC_WW_Pin1_4 234 239 PF00397 0.587
DOC_WW_Pin1_4 265 270 PF00397 0.555
DOC_WW_Pin1_4 283 288 PF00397 0.698
DOC_WW_Pin1_4 295 300 PF00397 0.620
DOC_WW_Pin1_4 306 311 PF00397 0.669
DOC_WW_Pin1_4 331 336 PF00397 0.719
DOC_WW_Pin1_4 36 41 PF00397 0.668
DOC_WW_Pin1_4 4 9 PF00397 0.687
DOC_WW_Pin1_4 445 450 PF00397 0.565
DOC_WW_Pin1_4 492 497 PF00397 0.660
DOC_WW_Pin1_4 50 55 PF00397 0.579
DOC_WW_Pin1_4 503 508 PF00397 0.517
DOC_WW_Pin1_4 648 653 PF00397 0.545
DOC_WW_Pin1_4 678 683 PF00397 0.794
DOC_WW_Pin1_4 717 722 PF00397 0.529
DOC_WW_Pin1_4 775 780 PF00397 0.583
DOC_WW_Pin1_4 906 911 PF00397 0.613
DOC_WW_Pin1_4 92 97 PF00397 0.726
DOC_WW_Pin1_4 938 943 PF00397 0.627
DOC_WW_Pin1_4 945 950 PF00397 0.578
LIG_14-3-3_CanoR_1 108 112 PF00244 0.597
LIG_14-3-3_CanoR_1 146 153 PF00244 0.548
LIG_14-3-3_CanoR_1 271 280 PF00244 0.830
LIG_14-3-3_CanoR_1 487 496 PF00244 0.597
LIG_14-3-3_CanoR_1 574 581 PF00244 0.559
LIG_14-3-3_CanoR_1 615 620 PF00244 0.793
LIG_14-3-3_CanoR_1 643 648 PF00244 0.688
LIG_14-3-3_CanoR_1 656 660 PF00244 0.498
LIG_14-3-3_CanoR_1 69 73 PF00244 0.675
LIG_14-3-3_CanoR_1 820 829 PF00244 0.663
LIG_14-3-3_CanoR_1 846 856 PF00244 0.701
LIG_14-3-3_CanoR_1 876 886 PF00244 0.599
LIG_14-3-3_CanoR_1 978 987 PF00244 0.569
LIG_BIR_III_2 483 487 PF00653 0.534
LIG_BIR_III_2 586 590 PF00653 0.670
LIG_BRCT_BRCA1_1 173 177 PF00533 0.711
LIG_BRCT_BRCA1_1 680 684 PF00533 0.686
LIG_BRCT_BRCA1_1 988 992 PF00533 0.423
LIG_BRCT_BRCA1_2 988 994 PF00533 0.424
LIG_Clathr_ClatBox_1 659 663 PF01394 0.623
LIG_Clathr_ClatBox_1 963 967 PF01394 0.527
LIG_DCNL_PONY_1 1 4 PF03556 0.698
LIG_FHA_1 286 292 PF00498 0.543
LIG_FHA_1 337 343 PF00498 0.615
LIG_FHA_1 602 608 PF00498 0.667
LIG_FHA_1 655 661 PF00498 0.514
LIG_FHA_1 855 861 PF00498 0.712
LIG_FHA_1 872 878 PF00498 0.573
LIG_FHA_1 941 947 PF00498 0.632
LIG_FHA_1 98 104 PF00498 0.552
LIG_FHA_2 193 199 PF00498 0.649
LIG_FHA_2 30 36 PF00498 0.663
LIG_FHA_2 343 349 PF00498 0.533
LIG_FHA_2 379 385 PF00498 0.649
LIG_FHA_2 471 477 PF00498 0.595
LIG_FHA_2 489 495 PF00498 0.576
LIG_FHA_2 77 83 PF00498 0.545
LIG_FHA_2 949 955 PF00498 0.614
LIG_LIR_Apic_2 989 995 PF02991 0.429
LIG_LIR_Gen_1 31 41 PF02991 0.689
LIG_LIR_Nem_3 223 229 PF02991 0.528
LIG_LIR_Nem_3 31 36 PF02991 0.694
LIG_LIR_Nem_3 990 996 PF02991 0.499
LIG_LYPXL_yS_3 226 229 PF13949 0.534
LIG_PCNA_TLS_4 121 128 PF02747 0.524
LIG_Pex14_2 992 996 PF04695 0.428
LIG_REV1ctd_RIR_1 990 994 PF16727 0.425
LIG_RPA_C_Fungi 663 675 PF08784 0.561
LIG_SH2_GRB2like 811 814 PF00017 0.475
LIG_SH2_NCK_1 33 37 PF00017 0.557
LIG_SH2_NCK_1 811 815 PF00017 0.606
LIG_SH2_SRC 811 814 PF00017 0.608
LIG_SH2_STAP1 811 815 PF00017 0.606
LIG_SH2_STAT3 379 382 PF00017 0.518
LIG_SH2_STAT5 127 130 PF00017 0.533
LIG_SH2_STAT5 187 190 PF00017 0.644
LIG_SH2_STAT5 631 634 PF00017 0.707
LIG_SH3_2 518 523 PF14604 0.535
LIG_SH3_2 841 846 PF14604 0.553
LIG_SH3_3 106 112 PF00018 0.688
LIG_SH3_3 131 137 PF00018 0.593
LIG_SH3_3 235 241 PF00018 0.636
LIG_SH3_3 284 290 PF00018 0.699
LIG_SH3_3 317 323 PF00018 0.634
LIG_SH3_3 430 436 PF00018 0.655
LIG_SH3_3 443 449 PF00018 0.560
LIG_SH3_3 454 460 PF00018 0.564
LIG_SH3_3 504 510 PF00018 0.651
LIG_SH3_3 513 519 PF00018 0.566
LIG_SH3_3 530 536 PF00018 0.687
LIG_SH3_3 538 544 PF00018 0.599
LIG_SH3_3 788 794 PF00018 0.572
LIG_SH3_3 835 841 PF00018 0.544
LIG_SH3_4 833 840 PF00018 0.673
LIG_SUMO_SIM_par_1 12 19 PF11976 0.702
LIG_SUMO_SIM_par_1 960 969 PF11976 0.467
LIG_UBA3_1 659 666 PF00899 0.576
LIG_WRC_WIRS_1 459 464 PF05994 0.578
LIG_WRPW_2 993 996 PF00400 0.564
LIG_WW_2 518 521 PF00397 0.527
LIG_WW_3 588 592 PF00397 0.720
MOD_CDC14_SPxK_1 118 121 PF00782 0.607
MOD_CDC14_SPxK_1 133 136 PF00782 0.607
MOD_CDC14_SPxK_1 268 271 PF00782 0.538
MOD_CDC14_SPxK_1 298 301 PF00782 0.666
MOD_CDK_SPxK_1 115 121 PF00069 0.620
MOD_CDK_SPxK_1 130 136 PF00069 0.594
MOD_CDK_SPxK_1 265 271 PF00069 0.545
MOD_CDK_SPxK_1 295 301 PF00069 0.668
MOD_CDK_SPxK_1 4 10 PF00069 0.687
MOD_CDK_SPxxK_3 221 228 PF00069 0.605
MOD_CDK_SPxxK_3 4 11 PF00069 0.689
MOD_CDK_SPxxK_3 492 499 PF00069 0.532
MOD_CK1_1 104 110 PF00069 0.671
MOD_CK1_1 130 136 PF00069 0.662
MOD_CK1_1 167 173 PF00069 0.715
MOD_CK1_1 249 255 PF00069 0.766
MOD_CK1_1 283 289 PF00069 0.700
MOD_CK1_1 309 315 PF00069 0.695
MOD_CK1_1 31 37 PF00069 0.666
MOD_CK1_1 461 467 PF00069 0.647
MOD_CK1_1 505 511 PF00069 0.576
MOD_CK1_1 55 61 PF00069 0.671
MOD_CK1_1 558 564 PF00069 0.652
MOD_CK1_1 568 574 PF00069 0.668
MOD_CK1_1 639 645 PF00069 0.578
MOD_CK1_1 760 766 PF00069 0.662
MOD_CK1_1 850 856 PF00069 0.629
MOD_CK1_1 871 877 PF00069 0.648
MOD_CK1_1 888 894 PF00069 0.550
MOD_CK1_1 95 101 PF00069 0.690
MOD_CK1_1 986 992 PF00069 0.423
MOD_CK2_1 166 172 PF00069 0.565
MOD_CK2_1 183 189 PF00069 0.635
MOD_CK2_1 29 35 PF00069 0.701
MOD_CK2_1 378 384 PF00069 0.729
MOD_CK2_1 720 726 PF00069 0.665
MOD_CK2_1 731 737 PF00069 0.581
MOD_CK2_1 760 766 PF00069 0.697
MOD_CK2_1 948 954 PF00069 0.658
MOD_DYRK1A_RPxSP_1 108 112 PF00069 0.548
MOD_GlcNHglycan 154 157 PF01048 0.677
MOD_GlcNHglycan 214 217 PF01048 0.682
MOD_GlcNHglycan 249 252 PF01048 0.732
MOD_GlcNHglycan 273 276 PF01048 0.609
MOD_GlcNHglycan 342 345 PF01048 0.722
MOD_GlcNHglycan 421 424 PF01048 0.555
MOD_GlcNHglycan 48 51 PF01048 0.685
MOD_GlcNHglycan 537 540 PF01048 0.690
MOD_GlcNHglycan 57 60 PF01048 0.666
MOD_GlcNHglycan 645 648 PF01048 0.748
MOD_GlcNHglycan 691 694 PF01048 0.646
MOD_GlcNHglycan 744 747 PF01048 0.633
MOD_GlcNHglycan 870 873 PF01048 0.586
MOD_GlcNHglycan 893 896 PF01048 0.530
MOD_GlcNHglycan 97 100 PF01048 0.651
MOD_GSK3_1 103 110 PF00069 0.559
MOD_GSK3_1 152 159 PF00069 0.682
MOD_GSK3_1 162 169 PF00069 0.638
MOD_GSK3_1 171 178 PF00069 0.542
MOD_GSK3_1 22 29 PF00069 0.695
MOD_GSK3_1 245 252 PF00069 0.761
MOD_GSK3_1 302 309 PF00069 0.657
MOD_GSK3_1 336 343 PF00069 0.667
MOD_GSK3_1 436 443 PF00069 0.716
MOD_GSK3_1 44 51 PF00069 0.614
MOD_GSK3_1 458 465 PF00069 0.684
MOD_GSK3_1 470 477 PF00069 0.666
MOD_GSK3_1 488 495 PF00069 0.690
MOD_GSK3_1 558 565 PF00069 0.617
MOD_GSK3_1 593 600 PF00069 0.548
MOD_GSK3_1 620 627 PF00069 0.628
MOD_GSK3_1 635 642 PF00069 0.512
MOD_GSK3_1 648 655 PF00069 0.488
MOD_GSK3_1 68 75 PF00069 0.699
MOD_GSK3_1 680 687 PF00069 0.617
MOD_GSK3_1 757 764 PF00069 0.699
MOD_GSK3_1 846 853 PF00069 0.649
MOD_GSK3_1 91 98 PF00069 0.631
MOD_GSK3_1 936 943 PF00069 0.630
MOD_GSK3_1 945 952 PF00069 0.556
MOD_GSK3_1 979 986 PF00069 0.533
MOD_LATS_1 572 578 PF00433 0.547
MOD_N-GLC_1 568 573 PF02516 0.542
MOD_N-GLC_1 592 597 PF02516 0.725
MOD_N-GLC_1 624 629 PF02516 0.541
MOD_N-GLC_1 877 882 PF02516 0.522
MOD_N-GLC_1 89 94 PF02516 0.557
MOD_NEK2_1 102 107 PF00069 0.674
MOD_NEK2_1 177 182 PF00069 0.625
MOD_NEK2_1 212 217 PF00069 0.622
MOD_NEK2_1 26 31 PF00069 0.603
MOD_NEK2_1 336 341 PF00069 0.779
MOD_NEK2_1 342 347 PF00069 0.712
MOD_NEK2_1 502 507 PF00069 0.698
MOD_NEK2_1 662 667 PF00069 0.556
MOD_NEK2_1 703 708 PF00069 0.641
MOD_NEK2_1 72 77 PF00069 0.714
MOD_NEK2_1 799 804 PF00069 0.554
MOD_NEK2_1 868 873 PF00069 0.584
MOD_NEK2_1 937 942 PF00069 0.632
MOD_PIKK_1 177 183 PF00454 0.546
MOD_PIKK_1 309 315 PF00454 0.711
MOD_PIKK_1 378 384 PF00454 0.651
MOD_PIKK_1 720 726 PF00454 0.694
MOD_PIKK_1 821 827 PF00454 0.623
MOD_PIKK_1 84 90 PF00454 0.606
MOD_PIKK_1 878 884 PF00454 0.644
MOD_PIKK_1 97 103 PF00454 0.663
MOD_PK_1 273 279 PF00069 0.651
MOD_PK_1 542 548 PF00069 0.607
MOD_PKA_1 440 446 PF00069 0.606
MOD_PKA_1 470 476 PF00069 0.583
MOD_PKA_1 542 548 PF00069 0.607
MOD_PKA_1 574 580 PF00069 0.552
MOD_PKA_1 820 826 PF00069 0.471
MOD_PKA_2 107 113 PF00069 0.726
MOD_PKA_2 145 151 PF00069 0.581
MOD_PKA_2 356 362 PF00069 0.706
MOD_PKA_2 440 446 PF00069 0.666
MOD_PKA_2 470 476 PF00069 0.595
MOD_PKA_2 574 580 PF00069 0.552
MOD_PKA_2 614 620 PF00069 0.770
MOD_PKA_2 655 661 PF00069 0.520
MOD_PKA_2 68 74 PF00069 0.707
MOD_PKA_2 773 779 PF00069 0.539
MOD_PKA_2 820 826 PF00069 0.471
MOD_PKA_2 983 989 PF00069 0.567
MOD_PKB_1 271 279 PF00069 0.662
MOD_PKB_1 818 826 PF00069 0.518
MOD_Plk_1 465 471 PF00069 0.579
MOD_Plk_1 757 763 PF00069 0.690
MOD_Plk_2-3 726 732 PF00069 0.532
MOD_Plk_4 342 348 PF00069 0.670
MOD_Plk_4 470 476 PF00069 0.583
MOD_Plk_4 655 661 PF00069 0.761
MOD_ProDKin_1 108 114 PF00069 0.556
MOD_ProDKin_1 115 121 PF00069 0.592
MOD_ProDKin_1 128 134 PF00069 0.487
MOD_ProDKin_1 162 168 PF00069 0.717
MOD_ProDKin_1 221 227 PF00069 0.743
MOD_ProDKin_1 234 240 PF00069 0.587
MOD_ProDKin_1 265 271 PF00069 0.555
MOD_ProDKin_1 283 289 PF00069 0.698
MOD_ProDKin_1 295 301 PF00069 0.619
MOD_ProDKin_1 306 312 PF00069 0.671
MOD_ProDKin_1 331 337 PF00069 0.720
MOD_ProDKin_1 36 42 PF00069 0.667
MOD_ProDKin_1 4 10 PF00069 0.687
MOD_ProDKin_1 445 451 PF00069 0.564
MOD_ProDKin_1 492 498 PF00069 0.664
MOD_ProDKin_1 50 56 PF00069 0.574
MOD_ProDKin_1 503 509 PF00069 0.518
MOD_ProDKin_1 648 654 PF00069 0.538
MOD_ProDKin_1 678 684 PF00069 0.798
MOD_ProDKin_1 717 723 PF00069 0.531
MOD_ProDKin_1 775 781 PF00069 0.581
MOD_ProDKin_1 906 912 PF00069 0.613
MOD_ProDKin_1 92 98 PF00069 0.728
MOD_ProDKin_1 938 944 PF00069 0.629
MOD_ProDKin_1 945 951 PF00069 0.573
MOD_SUMO_rev_2 148 156 PF00179 0.671
MOD_SUMO_rev_2 392 400 PF00179 0.639
MOD_SUMO_rev_2 698 706 PF00179 0.626
MOD_SUMO_rev_2 732 740 PF00179 0.596
TRG_DiLeu_BaLyEn_6 959 964 PF01217 0.471
TRG_DiLeu_LyEn_5 916 921 PF01217 0.569
TRG_ENDOCYTIC_2 226 229 PF00928 0.534
TRG_ENDOCYTIC_2 33 36 PF00928 0.690
TRG_ER_diArg_1 440 442 PF00400 0.606
TRG_ER_diArg_1 469 471 PF00400 0.581
TRG_ER_diArg_1 498 500 PF00400 0.545
TRG_ER_diArg_1 521 523 PF00400 0.677
TRG_ER_diArg_1 844 846 PF00400 0.796
TRG_ER_diArg_1 970 973 PF00400 0.571
TRG_Pf-PMV_PEXEL_1 121 125 PF00026 0.577
TRG_Pf-PMV_PEXEL_1 827 831 PF00026 0.644
TRG_Pf-PMV_PEXEL_1 962 967 PF00026 0.503

Homologs

Protein Taxonomy Sequence identity Coverage
A0A3Q8IHG2 Leishmania donovani 77% 100%
A4H7S6 Leishmania braziliensis 52% 99%
A4I9W0 Leishmania infantum 77% 100%
Q4Q354 Leishmania major 76% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS