Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9B4V9_LEIMU

TriTrypDb:

LmxM.33.1350

Length:

579

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B4V9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B4V9

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	409	413	PF00656	0.552
CLV_C14_Caspase3-7	478	482	PF00656	0.758
CLV_C14_Caspase3-7	568	572	PF00656	0.740
CLV_PCSK_KEX2_1	34	36	PF00082	0.574
CLV_PCSK_KEX2_1	525	527	PF00082	0.620
CLV_PCSK_PC1ET2_1	34	36	PF00082	0.574
CLV_PCSK_PC1ET2_1	525	527	PF00082	0.641
CLV_PCSK_SKI1_1	107	111	PF00082	0.783
CLV_PCSK_SKI1_1	193	197	PF00082	0.600
CLV_PCSK_SKI1_1	385	389	PF00082	0.566
CLV_PCSK_SKI1_1	497	501	PF00082	0.660
CLV_PCSK_SKI1_1	51	55	PF00082	0.661
DEG_SCF_FBW7_1	280	286	PF00400	0.650
DEG_SCF_FBW7_1	293	298	PF00400	0.723
DEG_SPOP_SBC_1	116	120	PF00917	0.757
DOC_CKS1_1	140	145	PF01111	0.780
DOC_CKS1_1	247	252	PF01111	0.744
DOC_CKS1_1	280	285	PF01111	0.766
DOC_CKS1_1	292	297	PF01111	0.616
DOC_CKS1_1	323	328	PF01111	0.838
DOC_CKS1_1	504	509	PF01111	0.671
DOC_CKS1_1	83	88	PF01111	0.682
DOC_MAPK_DCC_7	17	27	PF00069	0.360
DOC_MAPK_gen_1	17	27	PF00069	0.360
DOC_MAPK_MEF2A_6	262	269	PF00069	0.754
DOC_PP2B_LxvP_1	547	550	PF13499	0.786
DOC_SPAK_OSR1_1	26	30	PF12202	0.378
DOC_USP7_MATH_1	116	120	PF00917	0.751
DOC_USP7_MATH_1	240	244	PF00917	0.664
DOC_USP7_MATH_1	281	285	PF00917	0.784
DOC_USP7_MATH_1	295	299	PF00917	0.661
DOC_USP7_MATH_1	316	320	PF00917	0.753
DOC_USP7_MATH_1	358	362	PF00917	0.565
DOC_USP7_MATH_1	417	421	PF00917	0.590
DOC_USP7_MATH_1	45	49	PF00917	0.513
DOC_USP7_MATH_1	552	556	PF00917	0.691
DOC_USP7_UBL2_3	60	64	PF12436	0.550
DOC_WW_Pin1_4	139	144	PF00397	0.780
DOC_WW_Pin1_4	242	247	PF00397	0.695
DOC_WW_Pin1_4	260	265	PF00397	0.724
DOC_WW_Pin1_4	279	284	PF00397	0.738
DOC_WW_Pin1_4	285	290	PF00397	0.716
DOC_WW_Pin1_4	291	296	PF00397	0.757
DOC_WW_Pin1_4	300	305	PF00397	0.605
DOC_WW_Pin1_4	312	317	PF00397	0.714
DOC_WW_Pin1_4	319	324	PF00397	0.553
DOC_WW_Pin1_4	36	41	PF00397	0.570
DOC_WW_Pin1_4	412	417	PF00397	0.781
DOC_WW_Pin1_4	419	424	PF00397	0.583
DOC_WW_Pin1_4	503	508	PF00397	0.687
DOC_WW_Pin1_4	82	87	PF00397	0.692
LIG_14-3-3_CanoR_1	104	114	PF00244	0.587
LIG_14-3-3_CanoR_1	152	160	PF00244	0.628
LIG_14-3-3_CanoR_1	370	378	PF00244	0.614
LIG_14-3-3_CanoR_1	497	507	PF00244	0.621
LIG_14-3-3_CanoR_1	551	559	PF00244	0.636
LIG_APCC_ABBA_1	195	200	PF00400	0.535
LIG_BIR_II_1	1	5	PF00653	0.728
LIG_BIR_III_3	1	5	PF00653	0.728
LIG_CtBP_PxDLS_1	148	152	PF00389	0.664
LIG_FHA_1	129	135	PF00498	0.514
LIG_FHA_1	140	146	PF00498	0.745
LIG_FHA_1	169	175	PF00498	0.553
LIG_FHA_1	280	286	PF00498	0.767
LIG_FHA_1	499	505	PF00498	0.661
LIG_FHA_1	571	577	PF00498	0.755
LIG_FHA_1	83	89	PF00498	0.605
LIG_FHA_2	124	130	PF00498	0.702
LIG_FHA_2	361	367	PF00498	0.749
LIG_FHA_2	420	426	PF00498	0.640
LIG_FHA_2	476	482	PF00498	0.754
LIG_FHA_2	504	510	PF00498	0.563
LIG_FHA_2	52	58	PF00498	0.658
LIG_FHA_2	536	542	PF00498	0.693
LIG_FHA_2	552	558	PF00498	0.708
LIG_LIR_Apic_2	183	187	PF02991	0.562
LIG_LIR_Nem_3	528	533	PF02991	0.660
LIG_MYND_1	139	143	PF01753	0.524
LIG_NRBOX	69	75	PF00104	0.655
LIG_PALB2_WD40_1	186	194	PF16756	0.540
LIG_SH2_CRK	184	188	PF00017	0.557
LIG_SH2_STAP1	235	239	PF00017	0.542
LIG_SH2_STAT3	466	469	PF00017	0.551
LIG_SH2_STAT3	81	84	PF00017	0.734
LIG_SH2_STAT5	167	170	PF00017	0.562
LIG_SH2_STAT5	377	380	PF00017	0.597
LIG_SH2_STAT5	382	385	PF00017	0.563
LIG_SH2_STAT5	531	534	PF00017	0.672
LIG_SH2_STAT5	66	69	PF00017	0.649
LIG_SH2_STAT5	81	84	PF00017	0.486
LIG_SH3_3	134	140	PF00018	0.665
LIG_SH3_3	244	250	PF00018	0.825
LIG_SH3_3	258	264	PF00018	0.699
LIG_SH3_3	320	326	PF00018	0.713
LIG_SUMO_SIM_anti_2	518	525	PF11976	0.635
LIG_TRAF2_1	4	7	PF00917	0.592
LIG_TRAF2_1	506	509	PF00917	0.564
LIG_UBA3_1	521	525	PF00899	0.621
LIG_WRPW_2	63	66	PF00400	0.625
MOD_CDK_SPxxK_3	246	253	PF00069	0.741
MOD_CDK_SPxxK_3	419	426	PF00069	0.732
MOD_CK1_1	103	109	PF00069	0.753
MOD_CK1_1	118	124	PF00069	0.699
MOD_CK1_1	212	218	PF00069	0.823
MOD_CK1_1	242	248	PF00069	0.666
MOD_CK1_1	272	278	PF00069	0.686
MOD_CK1_1	312	318	PF00069	0.740
MOD_CK1_1	319	325	PF00069	0.729
MOD_CK1_1	401	407	PF00069	0.766
MOD_CK1_1	486	492	PF00069	0.664
MOD_CK1_1	535	541	PF00069	0.717
MOD_CK2_1	419	425	PF00069	0.626
MOD_CK2_1	503	509	PF00069	0.579
MOD_CK2_1	51	57	PF00069	0.662
MOD_CK2_1	551	557	PF00069	0.658
MOD_GlcNHglycan	242	245	PF01048	0.741
MOD_GlcNHglycan	297	300	PF01048	0.857
MOD_GlcNHglycan	311	314	PF01048	0.696
MOD_GlcNHglycan	318	321	PF01048	0.748
MOD_GlcNHglycan	333	336	PF01048	0.617
MOD_GlcNHglycan	360	363	PF01048	0.790
MOD_GlcNHglycan	403	406	PF01048	0.723
MOD_GlcNHglycan	419	422	PF01048	0.470
MOD_GlcNHglycan	446	449	PF01048	0.632
MOD_GlcNHglycan	453	456	PF01048	0.567
MOD_GlcNHglycan	483	488	PF01048	0.695
MOD_GlcNHglycan	534	537	PF01048	0.778
MOD_GlcNHglycan	544	547	PF01048	0.622
MOD_GlcNHglycan	554	557	PF01048	0.678
MOD_GSK3_1	103	110	PF00069	0.674
MOD_GSK3_1	112	119	PF00069	0.676
MOD_GSK3_1	120	127	PF00069	0.650
MOD_GSK3_1	229	236	PF00069	0.569
MOD_GSK3_1	242	249	PF00069	0.700
MOD_GSK3_1	265	272	PF00069	0.693
MOD_GSK3_1	275	282	PF00069	0.615
MOD_GSK3_1	291	298	PF00069	0.807
MOD_GSK3_1	312	319	PF00069	0.741
MOD_GSK3_1	331	338	PF00069	0.787
MOD_GSK3_1	339	346	PF00069	0.751
MOD_GSK3_1	352	359	PF00069	0.784
MOD_GSK3_1	395	402	PF00069	0.673
MOD_GSK3_1	403	410	PF00069	0.738
MOD_GSK3_1	411	418	PF00069	0.605
MOD_GSK3_1	51	58	PF00069	0.580
MOD_GSK3_1	532	539	PF00069	0.635
MOD_N-GLC_1	124	129	PF02516	0.672
MOD_NEK2_1	151	156	PF00069	0.646
MOD_NEK2_1	168	173	PF00069	0.565
MOD_NEK2_1	210	215	PF00069	0.706
MOD_NEK2_1	267	272	PF00069	0.767
MOD_NEK2_1	27	32	PF00069	0.541
MOD_NEK2_1	309	314	PF00069	0.778
MOD_NEK2_1	495	500	PF00069	0.722
MOD_NEK2_1	570	575	PF00069	0.642
MOD_NEK2_2	335	340	PF00069	0.686
MOD_NEK2_2	45	50	PF00069	0.548
MOD_PIKK_1	210	216	PF00454	0.758
MOD_PIKK_1	339	345	PF00454	0.793
MOD_PIKK_1	442	448	PF00454	0.631
MOD_PK_1	55	61	PF00069	0.654
MOD_PKA_1	525	531	PF00069	0.647
MOD_PKA_2	103	109	PF00069	0.759
MOD_PKA_2	112	118	PF00069	0.698
MOD_PKA_2	151	157	PF00069	0.627
MOD_PKA_2	331	337	PF00069	0.803
MOD_PKA_2	410	416	PF00069	0.544
MOD_PKA_2	525	531	PF00069	0.647
MOD_PKA_2	552	558	PF00069	0.700
MOD_Plk_1	128	134	PF00069	0.470
MOD_Plk_1	388	394	PF00069	0.553
MOD_Plk_1	570	576	PF00069	0.670
MOD_Plk_2-3	91	97	PF00069	0.734
MOD_Plk_4	335	341	PF00069	0.737
MOD_Plk_4	500	506	PF00069	0.620
MOD_Plk_4	77	83	PF00069	0.621
MOD_ProDKin_1	139	145	PF00069	0.779
MOD_ProDKin_1	242	248	PF00069	0.697
MOD_ProDKin_1	260	266	PF00069	0.725
MOD_ProDKin_1	279	285	PF00069	0.741
MOD_ProDKin_1	291	297	PF00069	0.759
MOD_ProDKin_1	300	306	PF00069	0.680
MOD_ProDKin_1	312	318	PF00069	0.716
MOD_ProDKin_1	319	325	PF00069	0.554
MOD_ProDKin_1	36	42	PF00069	0.573
MOD_ProDKin_1	412	418	PF00069	0.778
MOD_ProDKin_1	419	425	PF00069	0.577
MOD_ProDKin_1	503	509	PF00069	0.681
MOD_ProDKin_1	82	88	PF00069	0.699
MOD_SUMO_for_1	378	381	PF00179	0.690
TRG_DiLeu_BaEn_1	519	524	PF01217	0.634
TRG_DiLeu_BaEn_1	7	12	PF01217	0.563
TRG_DiLeu_BaEn_4	519	525	PF01217	0.640
TRG_DiLeu_BaLyEn_6	83	88	PF01217	0.682
TRG_ER_diArg_1	158	161	PF00400	0.604
TRG_ER_diArg_1	253	256	PF00400	0.777
TRG_ER_diArg_1	550	553	PF00400	0.768
TRG_Pf-PMV_PEXEL_1	390	394	PF00026	0.614
TRG_Pf-PMV_PEXEL_1	497	502	PF00026	0.740

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P6C9	Leptomonas seymouri	52%	99%
A0A3S7X7T6	Leishmania donovani	93%	100%
A4HAQ2	Leishmania braziliensis	76%	99%
A4I9U8	Leishmania infantum	91%	100%
Q4Q367	Leishmania major	91%	99%