OsmC-like protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

OsmC-like protein

Gene product:

OsmC-like protein, putative

Species:

Leishmania mexicana

UniProt:

E9B4V4_LEIMU

TriTrypDb:

LmxM.33.1300

Length:

359

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B4V4

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B4V4

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	247	251	PF00656	0.769
CLV_C14_Caspase3-7	300	304	PF00656	0.487
CLV_NRD_NRD_1	215	217	PF00675	0.778
CLV_NRD_NRD_1	268	270	PF00675	0.687
CLV_NRD_NRD_1	301	303	PF00675	0.792
CLV_NRD_NRD_1	63	65	PF00675	0.526
CLV_NRD_NRD_1	88	90	PF00675	0.623
CLV_PCSK_FUR_1	60	64	PF00082	0.582
CLV_PCSK_KEX2_1	215	217	PF00082	0.778
CLV_PCSK_KEX2_1	268	270	PF00082	0.691
CLV_PCSK_KEX2_1	301	303	PF00082	0.717
CLV_PCSK_KEX2_1	62	64	PF00082	0.511
CLV_PCSK_KEX2_1	88	90	PF00082	0.598
CLV_PCSK_PC1ET2_1	62	64	PF00082	0.511
DEG_Nend_Nbox_1	1	3	PF02207	0.680
DEG_SPOP_SBC_1	251	255	PF00917	0.761
DEG_SPOP_SBC_1	270	274	PF00917	0.490
DEG_SPOP_SBC_1	350	354	PF00917	0.619
DOC_MAPK_gen_1	95	102	PF00069	0.613
DOC_MAPK_MEF2A_6	95	102	PF00069	0.609
DOC_MAPK_NFAT4_5	95	103	PF00069	0.609
DOC_USP7_MATH_1	105	109	PF00917	0.653
DOC_USP7_MATH_1	154	158	PF00917	0.417
DOC_USP7_MATH_1	171	175	PF00917	0.258
DOC_USP7_MATH_1	24	28	PF00917	0.423
DOC_USP7_MATH_1	270	274	PF00917	0.717
DOC_USP7_MATH_1	305	309	PF00917	0.746
DOC_USP7_MATH_1	345	349	PF00917	0.757
DOC_USP7_MATH_1	350	354	PF00917	0.735
DOC_WW_Pin1_4	327	332	PF00397	0.615
DOC_WW_Pin1_4	333	338	PF00397	0.626
DOC_WW_Pin1_4	351	356	PF00397	0.804
LIG_14-3-3_CanoR_1	268	277	PF00244	0.700
LIG_14-3-3_CanoR_1	346	350	PF00244	0.514
LIG_14-3-3_CanoR_1	89	95	PF00244	0.514
LIG_Actin_WH2_2	4	22	PF00022	0.563
LIG_BIR_III_4	169	173	PF00653	0.402
LIG_FHA_1	252	258	PF00498	0.722
LIG_FHA_2	253	259	PF00498	0.720
LIG_LIR_Gen_1	68	78	PF02991	0.526
LIG_LIR_Nem_3	293	299	PF02991	0.764
LIG_LIR_Nem_3	303	309	PF02991	0.564
LIG_LIR_Nem_3	68	73	PF02991	0.518
LIG_SH2_CRK	70	74	PF00017	0.601
LIG_SH2_SRC	167	170	PF00017	0.334
LIG_SH2_SRC	37	40	PF00017	0.623
LIG_SH2_STAT5	167	170	PF00017	0.335
LIG_SH2_STAT5	25	28	PF00017	0.626
LIG_SH2_STAT5	37	40	PF00017	0.574
LIG_SH3_3	326	332	PF00018	0.765
LIG_SH3_3	339	345	PF00018	0.770
LIG_TRAF2_1	174	177	PF00917	0.358
LIG_UBA3_1	11	20	PF00899	0.475
MOD_CDK_SPK_2	353	358	PF00069	0.613
MOD_CDK_SPxxK_3	351	358	PF00069	0.716
MOD_CK1_1	253	259	PF00069	0.730
MOD_CK1_1	272	278	PF00069	0.669
MOD_CK1_1	320	326	PF00069	0.799
MOD_CK1_1	327	333	PF00069	0.752
MOD_CK1_1	353	359	PF00069	0.735
MOD_CK2_1	171	177	PF00069	0.356
MOD_CK2_1	226	232	PF00069	0.740
MOD_CK2_1	252	258	PF00069	0.722
MOD_CK2_1	90	96	PF00069	0.482
MOD_CK2_1	98	104	PF00069	0.475
MOD_Cter_Amidation	60	63	PF01082	0.578
MOD_GlcNHglycan	113	116	PF01048	0.626
MOD_GlcNHglycan	228	231	PF01048	0.732
MOD_GlcNHglycan	283	286	PF01048	0.733
MOD_GlcNHglycan	322	326	PF01048	0.795
MOD_GlcNHglycan	39	42	PF01048	0.583
MOD_GSK3_1	233	240	PF00069	0.693
MOD_GSK3_1	252	259	PF00069	0.661
MOD_GSK3_1	269	276	PF00069	0.593
MOD_GSK3_1	317	324	PF00069	0.692
MOD_GSK3_1	345	352	PF00069	0.772
MOD_N-GLC_1	154	159	PF02516	0.419
MOD_N-GLC_1	90	95	PF02516	0.463
MOD_NEK2_1	98	103	PF00069	0.545
MOD_NEK2_2	283	288	PF00069	0.619
MOD_NEK2_2	305	310	PF00069	0.491
MOD_PKA_2	105	111	PF00069	0.590
MOD_PKA_2	2	8	PF00069	0.543
MOD_PKA_2	345	351	PF00069	0.510
MOD_Plk_1	154	160	PF00069	0.424
MOD_Plk_1	90	96	PF00069	0.517
MOD_ProDKin_1	327	333	PF00069	0.613
MOD_ProDKin_1	351	357	PF00069	0.802
MOD_SUMO_for_1	48	51	PF00179	0.637
MOD_SUMO_rev_2	137	145	PF00179	0.335
TRG_ENDOCYTIC_2	70	73	PF00928	0.486
TRG_ER_diArg_1	214	216	PF00400	0.767
TRG_NLS_MonoExtN_4	60	66	PF00514	0.557
TRG_Pf-PMV_PEXEL_1	67	71	PF00026	0.556

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1ILB7	Leptomonas seymouri	59%	99%
A0A1X0PAR8	Trypanosomatidae	42%	100%
A0A3S7X7R4	Leishmania donovani	90%	100%
A0A422NU27	Trypanosoma rangeli	41%	100%
A4HAP7	Leishmania braziliensis	74%	100%
A4I9U3	Leishmania infantum	90%	100%
C9ZMT8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	39%	100%
Q4Q372	Leishmania major	89%	100%
V5DJV1	Trypanosoma cruzi	39%	100%