Guanylate cyclase domain-containing protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9B4U6_LEIMU

TriTrypDb:

LmxM.33.1230

Length:

1590

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	1
GO:0110165	cellular anatomical entity	1	1

Expansion

Sequence features

E9B4U6

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

No structure information available for this entry

Related structures:

Function

Biological processes
Term	Name	Level	Count
GO:0006139	nucleobase-containing compound metabolic process	3	10
GO:0006163	purine nucleotide metabolic process	5	10
GO:0006164	purine nucleotide biosynthetic process	6	10
GO:0006171	cAMP biosynthetic process	8	10
GO:0006725	cellular aromatic compound metabolic process	3	10
GO:0006753	nucleoside phosphate metabolic process	4	10
GO:0006793	phosphorus metabolic process	3	10
GO:0006796	phosphate-containing compound metabolic process	4	10
GO:0006807	nitrogen compound metabolic process	2	10
GO:0008152	metabolic process	1	10
GO:0009058	biosynthetic process	2	10
GO:0009117	nucleotide metabolic process	5	10
GO:0009150	purine ribonucleotide metabolic process	6	10
GO:0009152	purine ribonucleotide biosynthetic process	7	10
GO:0009165	nucleotide biosynthetic process	6	10
GO:0009187	cyclic nucleotide metabolic process	6	10
GO:0009190	cyclic nucleotide biosynthetic process	7	10
GO:0009259	ribonucleotide metabolic process	5	10
GO:0009260	ribonucleotide biosynthetic process	6	10
GO:0009987	cellular process	1	10
GO:0018130	heterocycle biosynthetic process	4	10
GO:0019438	aromatic compound biosynthetic process	4	10
GO:0019637	organophosphate metabolic process	3	10
GO:0019693	ribose phosphate metabolic process	4	10
GO:0034641	cellular nitrogen compound metabolic process	3	10
GO:0034654	nucleobase-containing compound biosynthetic process	4	10
GO:0044237	cellular metabolic process	2	10
GO:0044238	primary metabolic process	2	10
GO:0044249	cellular biosynthetic process	3	10
GO:0044271	cellular nitrogen compound biosynthetic process	4	10
GO:0044281	small molecule metabolic process	2	10
GO:0046058	cAMP metabolic process	7	10
GO:0046390	ribose phosphate biosynthetic process	5	10
GO:0046483	heterocycle metabolic process	3	10
GO:0052652	cyclic purine nucleotide metabolic process	6	10
GO:0055086	nucleobase-containing small molecule metabolic process	3	10
GO:0071704	organic substance metabolic process	2	10
GO:0072521	purine-containing compound metabolic process	4	10
GO:0072522	purine-containing compound biosynthetic process	5	10
GO:0090407	organophosphate biosynthetic process	4	10
GO:1901135	carbohydrate derivative metabolic process	3	10
GO:1901137	carbohydrate derivative biosynthetic process	4	10
GO:1901293	nucleoside phosphate biosynthetic process	5	10
GO:1901360	organic cyclic compound metabolic process	3	10
GO:1901362	organic cyclic compound biosynthetic process	4	10
GO:1901564	organonitrogen compound metabolic process	3	10
GO:1901566	organonitrogen compound biosynthetic process	4	10
GO:1901576	organic substance biosynthetic process	3	10

Could not find GO molecular_function term for this entry.

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	429	433	PF00656	0.555
CLV_C14_Caspase3-7	499	503	PF00656	0.588
CLV_NRD_NRD_1	1100	1102	PF00675	0.424
CLV_NRD_NRD_1	1137	1139	PF00675	0.505
CLV_NRD_NRD_1	124	126	PF00675	0.541
CLV_NRD_NRD_1	1355	1357	PF00675	0.678
CLV_NRD_NRD_1	1588	1590	PF00675	0.521
CLV_NRD_NRD_1	411	413	PF00675	0.420
CLV_NRD_NRD_1	422	424	PF00675	0.414
CLV_NRD_NRD_1	475	477	PF00675	0.524
CLV_NRD_NRD_1	524	526	PF00675	0.514
CLV_NRD_NRD_1	547	549	PF00675	0.623
CLV_NRD_NRD_1	57	59	PF00675	0.329
CLV_NRD_NRD_1	783	785	PF00675	0.476
CLV_NRD_NRD_1	801	803	PF00675	0.424
CLV_NRD_NRD_1	854	856	PF00675	0.612
CLV_NRD_NRD_1	873	875	PF00675	0.256
CLV_PCSK_FUR_1	409	413	PF00082	0.575
CLV_PCSK_KEX2_1	1100	1102	PF00082	0.424
CLV_PCSK_KEX2_1	1137	1139	PF00082	0.505
CLV_PCSK_KEX2_1	1158	1160	PF00082	0.563
CLV_PCSK_KEX2_1	1355	1357	PF00082	0.655
CLV_PCSK_KEX2_1	1588	1590	PF00082	0.550
CLV_PCSK_KEX2_1	30	32	PF00082	0.477
CLV_PCSK_KEX2_1	411	413	PF00082	0.424
CLV_PCSK_KEX2_1	474	476	PF00082	0.498
CLV_PCSK_KEX2_1	57	59	PF00082	0.334
CLV_PCSK_KEX2_1	783	785	PF00082	0.455
CLV_PCSK_KEX2_1	801	803	PF00082	0.427
CLV_PCSK_KEX2_1	853	855	PF00082	0.619
CLV_PCSK_KEX2_1	873	875	PF00082	0.185
CLV_PCSK_PC1ET2_1	1100	1102	PF00082	0.424
CLV_PCSK_PC1ET2_1	1158	1160	PF00082	0.567
CLV_PCSK_PC1ET2_1	30	32	PF00082	0.562
CLV_PCSK_SKI1_1	1063	1067	PF00082	0.568
CLV_PCSK_SKI1_1	1076	1080	PF00082	0.458
CLV_PCSK_SKI1_1	1120	1124	PF00082	0.617
CLV_PCSK_SKI1_1	1142	1146	PF00082	0.643
CLV_PCSK_SKI1_1	1539	1543	PF00082	0.456
CLV_PCSK_SKI1_1	1565	1569	PF00082	0.591
CLV_PCSK_SKI1_1	325	329	PF00082	0.522
CLV_PCSK_SKI1_1	442	446	PF00082	0.515
CLV_PCSK_SKI1_1	57	61	PF00082	0.599
CLV_PCSK_SKI1_1	573	577	PF00082	0.408
CLV_PCSK_SKI1_1	653	657	PF00082	0.439
CLV_PCSK_SKI1_1	74	78	PF00082	0.295
CLV_PCSK_SKI1_1	774	778	PF00082	0.396
CLV_PCSK_SKI1_1	972	976	PF00082	0.503
CLV_Separin_Metazoa	786	790	PF03568	0.610
DEG_APCC_DBOX_1	1062	1070	PF00400	0.555
DEG_APCC_DBOX_1	1538	1546	PF00400	0.505
DEG_APCC_DBOX_1	380	388	PF00400	0.560
DEG_APCC_DBOX_1	773	781	PF00400	0.511
DEG_APCC_DBOX_1	801	809	PF00400	0.545
DEG_APCC_KENBOX_2	125	129	PF00400	0.508
DEG_APCC_KENBOX_2	514	518	PF00400	0.439
DEG_APCC_KENBOX_2	714	718	PF00400	0.457
DEG_Nend_UBRbox_2	1	3	PF02207	0.593
DEG_SPOP_SBC_1	1147	1151	PF00917	0.549
DEG_SPOP_SBC_1	1176	1180	PF00917	0.678
DOC_CKS1_1	1087	1092	PF01111	0.501
DOC_CYCLIN_RxL_1	54	64	PF00134	0.400
DOC_CYCLIN_RxL_1	570	581	PF00134	0.531
DOC_CYCLIN_RxL_1	761	775	PF00134	0.572
DOC_CYCLIN_RxL_1	798	807	PF00134	0.636
DOC_CYCLIN_yCln2_LP_2	1145	1148	PF00134	0.447
DOC_CYCLIN_yCln2_LP_2	745	751	PF00134	0.546
DOC_CYCLIN_yCln2_LP_2	831	837	PF00134	0.448
DOC_MAPK_DCC_7	894	903	PF00069	0.503
DOC_MAPK_gen_1	1120	1128	PF00069	0.551
DOC_MAPK_gen_1	1137	1145	PF00069	0.489
DOC_MAPK_gen_1	1260	1269	PF00069	0.342
DOC_MAPK_gen_1	148	157	PF00069	0.554
DOC_MAPK_gen_1	853	859	PF00069	0.599
DOC_MAPK_gen_1	873	881	PF00069	0.178
DOC_MAPK_gen_1	972	981	PF00069	0.422
DOC_MAPK_HePTP_8	147	159	PF00069	0.476
DOC_MAPK_MEF2A_6	1392	1399	PF00069	0.504
DOC_MAPK_MEF2A_6	1409	1416	PF00069	0.451
DOC_MAPK_MEF2A_6	150	159	PF00069	0.482
DOC_MAPK_MEF2A_6	423	430	PF00069	0.482
DOC_MAPK_MEF2A_6	680	688	PF00069	0.463
DOC_MAPK_MEF2A_6	894	903	PF00069	0.503
DOC_MAPK_MEF2A_6	985	992	PF00069	0.435
DOC_PP1_RVXF_1	202	209	PF00149	0.361
DOC_PP1_RVXF_1	244	250	PF00149	0.454
DOC_PP1_RVXF_1	275	281	PF00149	0.455
DOC_PP1_RVXF_1	599	605	PF00149	0.487
DOC_PP1_RVXF_1	853	860	PF00149	0.548
DOC_PP1_RVXF_1	875	882	PF00149	0.412
DOC_PP1_RVXF_1	900	906	PF00149	0.396
DOC_PP2B_LxvP_1	1145	1148	PF13499	0.553
DOC_PP2B_LxvP_1	1414	1417	PF13499	0.605
DOC_PP2B_LxvP_1	769	772	PF13499	0.539
DOC_PP2B_PxIxI_1	985	991	PF00149	0.541
DOC_PP4_FxxP_1	258	261	PF00568	0.455
DOC_PP4_FxxP_1	328	331	PF00568	0.485
DOC_PP4_FxxP_1	452	455	PF00568	0.648
DOC_PP4_FxxP_1	936	939	PF00568	0.455
DOC_PP4_FxxP_1	981	984	PF00568	0.544
DOC_PP4_MxPP_1	1510	1513	PF00568	0.463
DOC_SPAK_OSR1_1	544	548	PF12202	0.620
DOC_USP7_MATH_1	1009	1013	PF00917	0.568
DOC_USP7_MATH_1	1071	1075	PF00917	0.500
DOC_USP7_MATH_1	1148	1152	PF00917	0.629
DOC_USP7_MATH_1	1167	1171	PF00917	0.354
DOC_USP7_MATH_1	1235	1239	PF00917	0.567
DOC_USP7_MATH_1	1243	1247	PF00917	0.558
DOC_USP7_MATH_1	1298	1302	PF00917	0.554
DOC_USP7_MATH_1	1311	1315	PF00917	0.568
DOC_USP7_MATH_1	1322	1326	PF00917	0.545
DOC_USP7_MATH_1	1363	1367	PF00917	0.693
DOC_USP7_MATH_1	1432	1436	PF00917	0.691
DOC_USP7_MATH_1	1479	1483	PF00917	0.583
DOC_USP7_MATH_1	1505	1509	PF00917	0.700
DOC_USP7_MATH_1	1556	1560	PF00917	0.524
DOC_USP7_MATH_1	1581	1585	PF00917	0.605
DOC_USP7_MATH_1	372	376	PF00917	0.624
DOC_USP7_MATH_1	5	9	PF00917	0.552
DOC_USP7_MATH_1	628	632	PF00917	0.437
DOC_USP7_MATH_1	645	649	PF00917	0.317
DOC_USP7_MATH_1	666	670	PF00917	0.475
DOC_USP7_MATH_1	772	776	PF00917	0.435
DOC_USP7_MATH_1	809	813	PF00917	0.549
DOC_USP7_MATH_1	915	919	PF00917	0.224
DOC_USP7_MATH_2	1520	1526	PF00917	0.439
DOC_USP7_UBL2_3	298	302	PF12436	0.443
DOC_USP7_UBL2_3	74	78	PF12436	0.426
DOC_WW_Pin1_4	1003	1008	PF00397	0.504
DOC_WW_Pin1_4	1086	1091	PF00397	0.491
DOC_WW_Pin1_4	1196	1201	PF00397	0.720
DOC_WW_Pin1_4	1251	1256	PF00397	0.621
DOC_WW_Pin1_4	1407	1412	PF00397	0.561
DOC_WW_Pin1_4	1435	1440	PF00397	0.446
DOC_WW_Pin1_4	1488	1493	PF00397	0.592
DOC_WW_Pin1_4	1508	1513	PF00397	0.519
DOC_WW_Pin1_4	1533	1538	PF00397	0.503
DOC_WW_Pin1_4	311	316	PF00397	0.437
DOC_WW_Pin1_4	826	831	PF00397	0.552
LIG_14-3-3_CanoR_1	1060	1066	PF00244	0.488
LIG_14-3-3_CanoR_1	1091	1097	PF00244	0.456
LIG_14-3-3_CanoR_1	1373	1381	PF00244	0.301
LIG_14-3-3_CanoR_1	1418	1428	PF00244	0.515
LIG_14-3-3_CanoR_1	1453	1463	PF00244	0.432
LIG_14-3-3_CanoR_1	1506	1510	PF00244	0.721
LIG_14-3-3_CanoR_1	1539	1548	PF00244	0.571
LIG_14-3-3_CanoR_1	277	281	PF00244	0.440
LIG_14-3-3_CanoR_1	548	554	PF00244	0.586
LIG_14-3-3_CanoR_1	810	817	PF00244	0.486
LIG_14-3-3_CanoR_1	853	858	PF00244	0.584
LIG_14-3-3_CanoR_1	873	881	PF00244	0.178
LIG_14-3-3_CanoR_1	985	991	PF00244	0.416
LIG_Actin_WH2_2	667	682	PF00022	0.500
LIG_Actin_WH2_2	889	904	PF00022	0.454
LIG_APCC_ABBA_1	59	64	PF00400	0.527
LIG_APCC_ABBA_1	933	938	PF00400	0.475
LIG_APCC_ABBAyCdc20_2	1123	1129	PF00400	0.538
LIG_BIR_III_2	1359	1363	PF00653	0.420
LIG_BIR_III_2	1517	1521	PF00653	0.569
LIG_BRCT_BRCA1_1	1150	1154	PF00533	0.642
LIG_BRCT_BRCA1_1	1576	1580	PF00533	0.615
LIG_BRCT_BRCA1_1	206	210	PF00533	0.456
LIG_BRCT_BRCA1_1	612	616	PF00533	0.460
LIG_BRCT_BRCA1_1	66	70	PF00533	0.309
LIG_BRCT_BRCA1_1	855	859	PF00533	0.545
LIG_Clathr_ClatBox_1	103	107	PF01394	0.464
LIG_Clathr_ClatBox_1	933	937	PF01394	0.537
LIG_CtBP_PxDLS_1	959	963	PF00389	0.509
LIG_EH1_1	1392	1400	PF00400	0.452
LIG_EH1_1	397	405	PF00400	0.539
LIG_eIF4E_1	1393	1399	PF01652	0.450
LIG_FHA_1	1045	1051	PF00498	0.507
LIG_FHA_1	1087	1093	PF00498	0.503
LIG_FHA_1	116	122	PF00498	0.554
LIG_FHA_1	1166	1172	PF00498	0.678
LIG_FHA_1	1190	1196	PF00498	0.753
LIG_FHA_1	1205	1211	PF00498	0.648
LIG_FHA_1	1216	1222	PF00498	0.508
LIG_FHA_1	1268	1274	PF00498	0.563
LIG_FHA_1	1394	1400	PF00498	0.494
LIG_FHA_1	215	221	PF00498	0.438
LIG_FHA_1	22	28	PF00498	0.518
LIG_FHA_1	556	562	PF00498	0.468
LIG_FHA_1	719	725	PF00498	0.505
LIG_FHA_1	826	832	PF00498	0.449
LIG_FHA_1	874	880	PF00498	0.418
LIG_FHA_1	928	934	PF00498	0.439
LIG_FHA_1	938	944	PF00498	0.442
LIG_FHA_1	966	972	PF00498	0.412
LIG_FHA_2	1103	1109	PF00498	0.678
LIG_FHA_2	114	120	PF00498	0.551
LIG_FHA_2	1177	1183	PF00498	0.690
LIG_FHA_2	1325	1331	PF00498	0.623
LIG_FHA_2	290	296	PF00498	0.527
LIG_FHA_2	564	570	PF00498	0.465
LIG_FHA_2	689	695	PF00498	0.489
LIG_FHA_2	78	84	PF00498	0.464
LIG_FHA_2	859	865	PF00498	0.521
LIG_Integrin_isoDGR_2	1494	1496	PF01839	0.503
LIG_Integrin_RGD_1	593	595	PF01839	0.568
LIG_LIR_Apic_2	316	321	PF02991	0.484
LIG_LIR_Apic_2	450	455	PF02991	0.633
LIG_LIR_Apic_2	978	984	PF02991	0.545
LIG_LIR_Gen_1	1248	1258	PF02991	0.686
LIG_LIR_Gen_1	1382	1390	PF02991	0.420
LIG_LIR_Gen_1	1466	1473	PF02991	0.355
LIG_LIR_Gen_1	1481	1492	PF02991	0.434
LIG_LIR_Gen_1	2	12	PF02991	0.539
LIG_LIR_Gen_1	207	218	PF02991	0.459
LIG_LIR_Gen_1	279	289	PF02991	0.460
LIG_LIR_Gen_1	323	334	PF02991	0.485
LIG_LIR_Gen_1	353	361	PF02991	0.506
LIG_LIR_Gen_1	386	396	PF02991	0.414
LIG_LIR_Gen_1	582	592	PF02991	0.520
LIG_LIR_Gen_1	609	620	PF02991	0.459
LIG_LIR_Gen_1	833	843	PF02991	0.517
LIG_LIR_Gen_1	929	939	PF02991	0.459
LIG_LIR_LC3C_4	1085	1088	PF02991	0.473
LIG_LIR_LC3C_4	930	935	PF02991	0.529
LIG_LIR_Nem_3	1236	1242	PF02991	0.607
LIG_LIR_Nem_3	1248	1253	PF02991	0.545
LIG_LIR_Nem_3	1382	1387	PF02991	0.480
LIG_LIR_Nem_3	1389	1393	PF02991	0.476
LIG_LIR_Nem_3	1466	1471	PF02991	0.616
LIG_LIR_Nem_3	1481	1487	PF02991	0.382
LIG_LIR_Nem_3	207	213	PF02991	0.455
LIG_LIR_Nem_3	279	284	PF02991	0.493
LIG_LIR_Nem_3	323	329	PF02991	0.450
LIG_LIR_Nem_3	353	358	PF02991	0.457
LIG_LIR_Nem_3	386	391	PF02991	0.420
LIG_LIR_Nem_3	422	428	PF02991	0.527
LIG_LIR_Nem_3	569	575	PF02991	0.370
LIG_LIR_Nem_3	582	588	PF02991	0.404
LIG_LIR_Nem_3	609	615	PF02991	0.455
LIG_LIR_Nem_3	617	623	PF02991	0.405
LIG_LIR_Nem_3	631	637	PF02991	0.358
LIG_LIR_Nem_3	668	674	PF02991	0.497
LIG_LIR_Nem_3	833	838	PF02991	0.547
LIG_LIR_Nem_3	856	862	PF02991	0.378
LIG_LIR_Nem_3	918	922	PF02991	0.484
LIG_LIR_Nem_3	929	935	PF02991	0.453
LIG_LYPXL_SIV_4	772	780	PF13949	0.509
LIG_LYPXL_yS_3	425	428	PF13949	0.550
LIG_NRBOX	1276	1282	PF00104	0.585
LIG_OCRL_FandH_1	748	760	PF00620	0.503
LIG_PCNA_yPIPBox_3	1272	1281	PF02747	0.527
LIG_PCNA_yPIPBox_3	515	524	PF02747	0.469
LIG_Pex14_2	208	212	PF04695	0.431
LIG_Pex14_2	616	620	PF04695	0.374
LIG_PTB_Apo_2	212	219	PF02174	0.446
LIG_PTB_Phospho_1	212	218	PF10480	0.414
LIG_SH2_CRK	231	235	PF00017	0.300
LIG_SH2_CRK	301	305	PF00017	0.380
LIG_SH2_CRK	773	777	PF00017	0.537
LIG_SH2_CRK	908	912	PF00017	0.429
LIG_SH2_NCK_1	612	616	PF00017	0.447
LIG_SH2_PTP2	318	321	PF00017	0.500
LIG_SH2_PTP2	634	637	PF00017	0.493
LIG_SH2_SRC	318	321	PF00017	0.500
LIG_SH2_SRC	62	65	PF00017	0.525
LIG_SH2_STAP1	1384	1388	PF00017	0.467
LIG_SH2_STAP1	612	616	PF00017	0.447
LIG_SH2_STAT3	191	194	PF00017	0.390
LIG_SH2_STAT3	910	913	PF00017	0.455
LIG_SH2_STAT5	1393	1396	PF00017	0.478
LIG_SH2_STAT5	1547	1550	PF00017	0.488
LIG_SH2_STAT5	318	321	PF00017	0.409
LIG_SH2_STAT5	560	563	PF00017	0.531
LIG_SH2_STAT5	618	621	PF00017	0.429
LIG_SH2_STAT5	634	637	PF00017	0.314
LIG_SH2_STAT5	723	726	PF00017	0.542
LIG_SH2_STAT5	770	773	PF00017	0.539
LIG_SH2_STAT5	871	874	PF00017	0.502
LIG_SH2_STAT5	883	886	PF00017	0.400
LIG_SH2_STAT5	910	913	PF00017	0.403
LIG_SH2_STAT5	922	925	PF00017	0.369
LIG_SH2_STAT5	932	935	PF00017	0.374
LIG_SH3_1	1409	1415	PF00018	0.590
LIG_SH3_3	1084	1090	PF00018	0.489
LIG_SH3_3	1335	1341	PF00018	0.639
LIG_SH3_3	1409	1415	PF00018	0.593
LIG_SH3_3	1425	1431	PF00018	0.698
LIG_SH3_3	1436	1442	PF00018	0.529
LIG_SH3_3	1567	1573	PF00018	0.562
LIG_SH3_3	213	219	PF00018	0.392
LIG_SH3_3	388	394	PF00018	0.496
LIG_SH3_3	415	421	PF00018	0.467
LIG_SH3_3	482	488	PF00018	0.329
LIG_SH3_3	893	899	PF00018	0.510
LIG_SUMO_SIM_anti_2	1032	1038	PF11976	0.541
LIG_SUMO_SIM_par_1	113	119	PF11976	0.454
LIG_SUMO_SIM_par_1	1265	1270	PF11976	0.323
LIG_TRAF2_1	1106	1109	PF00917	0.602
LIG_TRAF2_1	492	495	PF00917	0.514
LIG_TRAF2_1	81	84	PF00917	0.543
LIG_TRAF2_1	861	864	PF00917	0.520
LIG_TYR_ITIM	771	776	PF00017	0.538
LIG_TYR_ITSM	928	935	PF00017	0.481
LIG_UBA3_1	103	111	PF00899	0.423
LIG_UBA3_1	507	515	PF00899	0.464
LIG_UBA3_1	520	526	PF00899	0.403
LIG_WRC_WIRS_1	708	713	PF05994	0.461
LIG_WRC_WIRS_1	916	921	PF05994	0.341
MOD_CDC14_SPxK_1	1536	1539	PF00782	0.381
MOD_CDC14_SPxK_1	829	832	PF00782	0.456
MOD_CDK_SPK_2	1086	1091	PF00069	0.277
MOD_CDK_SPxK_1	1533	1539	PF00069	0.397
MOD_CDK_SPxK_1	826	832	PF00069	0.466
MOD_CK1_1	1003	1009	PF00069	0.480
MOD_CK1_1	1012	1018	PF00069	0.609
MOD_CK1_1	1103	1109	PF00069	0.741
MOD_CK1_1	1149	1155	PF00069	0.566
MOD_CK1_1	1251	1257	PF00069	0.665
MOD_CK1_1	1325	1331	PF00069	0.612
MOD_CK1_1	1366	1372	PF00069	0.647
MOD_CK1_1	1423	1429	PF00069	0.662
MOD_CK1_1	1434	1440	PF00069	0.699
MOD_CK1_1	1446	1452	PF00069	0.712
MOD_CK1_1	1457	1463	PF00069	0.604
MOD_CK1_1	1475	1481	PF00069	0.380
MOD_CK1_1	1482	1488	PF00069	0.567
MOD_CK1_1	1508	1514	PF00069	0.634
MOD_CK1_1	1525	1531	PF00069	0.622
MOD_CK1_1	214	220	PF00069	0.459
MOD_CK1_1	279	285	PF00069	0.458
MOD_CK1_1	291	297	PF00069	0.420
MOD_CK1_1	314	320	PF00069	0.469
MOD_CK1_1	370	376	PF00069	0.668
MOD_CK1_1	52	58	PF00069	0.346
MOD_CK1_1	555	561	PF00069	0.340
MOD_CK1_1	710	716	PF00069	0.462
MOD_CK1_1	824	830	PF00069	0.549
MOD_CK1_1	928	934	PF00069	0.504
MOD_CK2_1	1102	1108	PF00069	0.672
MOD_CK2_1	1167	1173	PF00069	0.681
MOD_CK2_1	1176	1182	PF00069	0.580
MOD_CK2_1	1298	1304	PF00069	0.556
MOD_CK2_1	1324	1330	PF00069	0.584
MOD_CK2_1	1475	1481	PF00069	0.577
MOD_CK2_1	1525	1531	PF00069	0.699
MOD_CK2_1	279	285	PF00069	0.458
MOD_CK2_1	289	295	PF00069	0.487
MOD_CK2_1	430	436	PF00069	0.402
MOD_CK2_1	489	495	PF00069	0.542
MOD_CK2_1	563	569	PF00069	0.475
MOD_CK2_1	710	716	PF00069	0.498
MOD_CK2_1	77	83	PF00069	0.426
MOD_CK2_1	858	864	PF00069	0.530
MOD_GlcNHglycan	1027	1030	PF01048	0.591
MOD_GlcNHglycan	1039	1042	PF01048	0.440
MOD_GlcNHglycan	1073	1076	PF01048	0.502
MOD_GlcNHglycan	1179	1182	PF01048	0.745
MOD_GlcNHglycan	1196	1199	PF01048	0.730
MOD_GlcNHglycan	1285	1288	PF01048	0.567
MOD_GlcNHglycan	1299	1303	PF01048	0.598
MOD_GlcNHglycan	1315	1318	PF01048	0.491
MOD_GlcNHglycan	1327	1330	PF01048	0.522
MOD_GlcNHglycan	1344	1347	PF01048	0.694
MOD_GlcNHglycan	1365	1368	PF01048	0.686
MOD_GlcNHglycan	1369	1372	PF01048	0.645
MOD_GlcNHglycan	1445	1448	PF01048	0.733
MOD_GlcNHglycan	1456	1459	PF01048	0.450
MOD_GlcNHglycan	1475	1478	PF01048	0.398
MOD_GlcNHglycan	1542	1545	PF01048	0.451
MOD_GlcNHglycan	1585	1588	PF01048	0.543
MOD_GlcNHglycan	322	325	PF01048	0.487
MOD_GlcNHglycan	405	408	PF01048	0.505
MOD_GlcNHglycan	432	435	PF01048	0.558
MOD_GlcNHglycan	502	505	PF01048	0.563
MOD_GlcNHglycan	530	533	PF01048	0.538
MOD_GlcNHglycan	608	611	PF01048	0.399
MOD_GlcNHglycan	663	666	PF01048	0.516
MOD_GlcNHglycan	688	691	PF01048	0.390
MOD_GlcNHglycan	697	700	PF01048	0.374
MOD_GlcNHglycan	811	814	PF01048	0.524
MOD_GlcNHglycan	919	922	PF01048	0.486
MOD_GSK3_1	1009	1016	PF00069	0.573
MOD_GSK3_1	1100	1107	PF00069	0.672
MOD_GSK3_1	1211	1218	PF00069	0.580
MOD_GSK3_1	1245	1252	PF00069	0.598
MOD_GSK3_1	1340	1347	PF00069	0.521
MOD_GSK3_1	1363	1370	PF00069	0.661
MOD_GSK3_1	1419	1426	PF00069	0.687
MOD_GSK3_1	1431	1438	PF00069	0.640
MOD_GSK3_1	1448	1455	PF00069	0.663
MOD_GSK3_1	1471	1478	PF00069	0.528
MOD_GSK3_1	1479	1486	PF00069	0.512
MOD_GSK3_1	1508	1515	PF00069	0.665
MOD_GSK3_1	1572	1579	PF00069	0.504
MOD_GSK3_1	279	286	PF00069	0.375
MOD_GSK3_1	305	312	PF00069	0.368
MOD_GSK3_1	399	406	PF00069	0.584
MOD_GSK3_1	49	56	PF00069	0.335
MOD_GSK3_1	524	531	PF00069	0.461
MOD_GSK3_1	549	556	PF00069	0.509
MOD_GSK3_1	563	570	PF00069	0.415
MOD_GSK3_1	584	591	PF00069	0.532
MOD_GSK3_1	606	613	PF00069	0.429
MOD_GSK3_1	661	668	PF00069	0.497
MOD_GSK3_1	821	828	PF00069	0.549
MOD_GSK3_1	923	930	PF00069	0.421
MOD_GSK3_1	986	993	PF00069	0.479
MOD_N-GLC_1	1330	1335	PF02516	0.621
MOD_N-GLC_1	134	139	PF02516	0.503
MOD_N-GLC_1	1351	1356	PF02516	0.709
MOD_N-GLC_1	214	219	PF02516	0.368
MOD_N-GLC_1	610	615	PF02516	0.401
MOD_N-GLC_1	637	642	PF02516	0.518
MOD_N-GLC_1	78	83	PF02516	0.526
MOD_N-GLC_1	926	931	PF02516	0.543
MOD_NEK2_1	1000	1005	PF00069	0.239
MOD_NEK2_1	1061	1066	PF00069	0.512
MOD_NEK2_1	1267	1272	PF00069	0.560
MOD_NEK2_1	1344	1349	PF00069	0.555
MOD_NEK2_1	1388	1393	PF00069	0.464
MOD_NEK2_1	1443	1448	PF00069	0.470
MOD_NEK2_1	1540	1545	PF00069	0.313
MOD_NEK2_1	1574	1579	PF00069	0.583
MOD_NEK2_1	235	240	PF00069	0.409
MOD_NEK2_1	430	435	PF00069	0.545
MOD_NEK2_1	489	494	PF00069	0.671
MOD_NEK2_1	500	505	PF00069	0.531
MOD_NEK2_1	576	581	PF00069	0.499
MOD_NEK2_1	606	611	PF00069	0.491
MOD_NEK2_1	66	71	PF00069	0.518
MOD_NEK2_1	679	684	PF00069	0.450
MOD_NEK2_1	688	693	PF00069	0.425
MOD_NEK2_1	718	723	PF00069	0.470
MOD_NEK2_1	740	745	PF00069	0.556
MOD_NEK2_1	77	82	PF00069	0.306
MOD_NEK2_1	825	830	PF00069	0.442
MOD_NEK2_1	953	958	PF00069	0.477
MOD_NEK2_1	964	969	PF00069	0.402
MOD_NEK2_1	99	104	PF00069	0.490
MOD_NEK2_2	1479	1484	PF00069	0.493
MOD_NEK2_2	666	671	PF00069	0.468
MOD_NEK2_2	778	783	PF00069	0.519
MOD_NEK2_2	986	991	PF00069	0.244
MOD_PIKK_1	1448	1454	PF00454	0.741
MOD_PIKK_1	49	55	PF00454	0.470
MOD_PIKK_1	490	496	PF00454	0.572
MOD_PIKK_1	718	724	PF00454	0.489
MOD_PK_1	78	84	PF00069	0.286
MOD_PK_1	853	859	PF00069	0.632
MOD_PKA_1	1100	1106	PF00069	0.441
MOD_PKA_1	853	859	PF00069	0.632
MOD_PKA_1	873	879	PF00069	0.255
MOD_PKA_2	1059	1065	PF00069	0.558
MOD_PKA_2	1100	1106	PF00069	0.441
MOD_PKA_2	1312	1318	PF00069	0.462
MOD_PKA_2	1347	1353	PF00069	0.612
MOD_PKA_2	1354	1360	PF00069	0.639
MOD_PKA_2	1372	1378	PF00069	0.429
MOD_PKA_2	1452	1458	PF00069	0.459
MOD_PKA_2	1479	1485	PF00069	0.545
MOD_PKA_2	1495	1501	PF00069	0.530
MOD_PKA_2	1505	1511	PF00069	0.717
MOD_PKA_2	1522	1528	PF00069	0.685
MOD_PKA_2	276	282	PF00069	0.447
MOD_PKA_2	49	55	PF00069	0.502
MOD_PKA_2	524	530	PF00069	0.504
MOD_PKA_2	686	692	PF00069	0.496
MOD_PKA_2	809	815	PF00069	0.493
MOD_PKA_2	853	859	PF00069	0.581
MOD_PKA_2	872	878	PF00069	0.194
MOD_Plk_1	1044	1050	PF00069	0.488
MOD_Plk_1	1235	1241	PF00069	0.569
MOD_Plk_1	1248	1254	PF00069	0.645
MOD_Plk_1	134	140	PF00069	0.530
MOD_Plk_1	204	210	PF00069	0.360
MOD_Plk_1	214	220	PF00069	0.347
MOD_Plk_1	367	373	PF00069	0.561
MOD_Plk_1	414	420	PF00069	0.522
MOD_Plk_1	567	573	PF00069	0.433
MOD_Plk_1	72	78	PF00069	0.529
MOD_Plk_1	821	827	PF00069	0.438
MOD_Plk_1	83	89	PF00069	0.468
MOD_Plk_1	965	971	PF00069	0.456
MOD_Plk_4	1032	1038	PF00069	0.583
MOD_Plk_4	1044	1050	PF00069	0.440
MOD_Plk_4	1215	1221	PF00069	0.451
MOD_Plk_4	1505	1511	PF00069	0.606
MOD_Plk_4	204	210	PF00069	0.344
MOD_Plk_4	276	282	PF00069	0.488
MOD_Plk_4	314	320	PF00069	0.464
MOD_Plk_4	383	389	PF00069	0.488
MOD_Plk_4	399	405	PF00069	0.405
MOD_Plk_4	414	420	PF00069	0.439
MOD_Plk_4	567	573	PF00069	0.464
MOD_Plk_4	666	672	PF00069	0.502
MOD_Plk_4	740	746	PF00069	0.496
MOD_Plk_4	928	934	PF00069	0.504
MOD_Plk_4	953	959	PF00069	0.539
MOD_Plk_4	975	981	PF00069	0.419
MOD_ProDKin_1	1003	1009	PF00069	0.510
MOD_ProDKin_1	1086	1092	PF00069	0.497
MOD_ProDKin_1	1196	1202	PF00069	0.714
MOD_ProDKin_1	1251	1257	PF00069	0.618
MOD_ProDKin_1	1407	1413	PF00069	0.567
MOD_ProDKin_1	1435	1441	PF00069	0.448
MOD_ProDKin_1	1488	1494	PF00069	0.598
MOD_ProDKin_1	1508	1514	PF00069	0.522
MOD_ProDKin_1	1533	1539	PF00069	0.500
MOD_ProDKin_1	311	317	PF00069	0.435
MOD_ProDKin_1	826	832	PF00069	0.552
MOD_SUMO_for_1	40	43	PF00179	0.510
MOD_SUMO_rev_2	107	112	PF00179	0.361
MOD_SUMO_rev_2	1103	1113	PF00179	0.573
MOD_SUMO_rev_2	1116	1122	PF00179	0.635
MOD_SUMO_rev_2	1526	1536	PF00179	0.359
MOD_SUMO_rev_2	967	976	PF00179	0.479
TRG_DiLeu_BaEn_1	127	132	PF01217	0.581
TRG_DiLeu_BaEn_1	1276	1281	PF01217	0.292
TRG_DiLeu_BaEn_1	516	521	PF01217	0.457
TRG_DiLeu_BaEn_4	960	966	PF01217	0.515
TRG_DiLeu_BaLyEn_6	55	60	PF01217	0.416
TRG_DiLeu_BaLyEn_6	896	901	PF01217	0.503
TRG_DiLeu_LyEn_5	127	132	PF01217	0.581
TRG_ENDOCYTIC_2	1384	1387	PF00928	0.483
TRG_ENDOCYTIC_2	231	234	PF00928	0.346
TRG_ENDOCYTIC_2	250	253	PF00928	0.344
TRG_ENDOCYTIC_2	326	329	PF00928	0.450
TRG_ENDOCYTIC_2	425	428	PF00928	0.543
TRG_ENDOCYTIC_2	612	615	PF00928	0.426
TRG_ENDOCYTIC_2	634	637	PF00928	0.381
TRG_ENDOCYTIC_2	671	674	PF00928	0.533
TRG_ENDOCYTIC_2	773	776	PF00928	0.537
TRG_ENDOCYTIC_2	883	886	PF00928	0.473
TRG_ENDOCYTIC_2	908	911	PF00928	0.365
TRG_ENDOCYTIC_2	932	935	PF00928	0.476
TRG_ER_diArg_1	1136	1138	PF00400	0.497
TRG_ER_diArg_1	147	150	PF00400	0.433
TRG_ER_diArg_1	161	164	PF00400	0.377
TRG_ER_diArg_1	408	411	PF00400	0.435
TRG_ER_diArg_1	47	50	PF00400	0.339
TRG_ER_diArg_1	473	476	PF00400	0.509
TRG_ER_diArg_1	57	59	PF00400	0.320
TRG_ER_diArg_1	782	784	PF00400	0.495
TRG_ER_diArg_1	801	803	PF00400	0.390
TRG_ER_diArg_1	853	855	PF00400	0.648
TRG_ER_diArg_1	872	874	PF00400	0.209
TRG_NES_CRM1_1	960	973	PF08389	0.521
TRG_Pf-PMV_PEXEL_1	101	105	PF00026	0.573
TRG_Pf-PMV_PEXEL_1	130	134	PF00026	0.554
TRG_Pf-PMV_PEXEL_1	1553	1557	PF00026	0.561
TRG_Pf-PMV_PEXEL_1	58	63	PF00026	0.474

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I4T5	Leptomonas seymouri	56%	100%
A0A1X0P9N1	Trypanosomatidae	34%	100%
A0A3R7KSR2	Trypanosoma rangeli	33%	100%
A0A3S5H7W4	Leishmania donovani	89%	100%
A4HAP0	Leishmania braziliensis	71%	100%
A4I9T5	Leishmania infantum	90%	100%
C9ZMU5	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	30%	100%
Q4Q380	Leishmania major	88%	100%
V5DJU3	Trypanosoma cruzi	33%	100%