Enriched_in_surface-labeled_proteome_protein_-_putative

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

Enriched in surface-labeled proteome protein 11, putative

Species:

Leishmania mexicana

UniProt:

E9B4U0_LEIMU

TriTrypDb:

LmxM.33.1175

Length:

277

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	yes	yes: 4, no: 2
NetGPI	no	yes: 0, no: 6

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	6
GO:0110165	cellular anatomical entity	1	6
GO:0020016	ciliary pocket	2	1

Expansion

Sequence features

E9B4U0

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B4U0

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	13	15	PF00675	0.640
CLV_PCSK_FUR_1	11	15	PF00082	0.599
CLV_PCSK_KEX2_1	13	15	PF00082	0.640
CLV_PCSK_SKI1_1	168	172	PF00082	0.435
CLV_PCSK_SKI1_1	51	55	PF00082	0.724
DOC_CYCLIN_yCln2_LP_2	251	254	PF00134	0.657
DOC_PP2B_LxvP_1	251	254	PF13499	0.657
DOC_USP7_MATH_1	177	181	PF00917	0.678
DOC_USP7_MATH_1	264	268	PF00917	0.675
DOC_USP7_MATH_1	34	38	PF00917	0.518
DOC_WW_Pin1_4	203	208	PF00397	0.620
LIG_14-3-3_CanoR_1	11	21	PF00244	0.483
LIG_AP2alpha_2	115	117	PF02296	0.362
LIG_BIR_II_1	1	5	PF00653	0.619
LIG_BRCT_BRCA1_1	196	200	PF00533	0.616
LIG_CtBP_PxDLS_1	253	257	PF00389	0.655
LIG_FHA_1	16	22	PF00498	0.459
LIG_FHA_1	167	173	PF00498	0.604
LIG_FHA_1	222	228	PF00498	0.688
LIG_FHA_1	79	85	PF00498	0.370
LIG_FHA_2	199	205	PF00498	0.655
LIG_LIR_Gen_1	145	153	PF02991	0.383
LIG_LIR_Gen_1	162	172	PF02991	0.674
LIG_LIR_Nem_3	145	150	PF02991	0.424
LIG_LIR_Nem_3	162	167	PF02991	0.648
LIG_LYPXL_yS_3	249	252	PF13949	0.664
LIG_MYND_1	112	116	PF01753	0.384
LIG_MYND_1	250	254	PF01753	0.657
LIG_NRBOX	20	26	PF00104	0.523
LIG_Pex14_1	160	164	PF04695	0.604
LIG_PTB_Apo_2	84	91	PF02174	0.375
LIG_PTB_Phospho_1	84	90	PF10480	0.436
LIG_SH2_CRK	164	168	PF00017	0.718
LIG_SH2_GRB2like	85	88	PF00017	0.398
LIG_SH2_NCK_1	195	199	PF00017	0.672
LIG_SH2_SRC	85	88	PF00017	0.398
LIG_SH2_STAT5	151	154	PF00017	0.312
LIG_SH2_STAT5	85	88	PF00017	0.398
LIG_SH2_STAT5	90	93	PF00017	0.348
LIG_SH3_3	176	182	PF00018	0.636
LIG_SH3_3	204	210	PF00018	0.655
LIG_SH3_3	214	220	PF00018	0.727
LIG_SH3_3	247	253	PF00018	0.753
LIG_TRFH_1	249	253	PF08558	0.662
MOD_CK1_1	142	148	PF00069	0.407
MOD_CK1_1	212	218	PF00069	0.697
MOD_CK2_1	198	204	PF00069	0.653
MOD_CK2_1	235	241	PF00069	0.734
MOD_GlcNHglycan	1	4	PF01048	0.698
MOD_GlcNHglycan	196	199	PF01048	0.497
MOD_GlcNHglycan	211	214	PF01048	0.446
MOD_GlcNHglycan	25	28	PF01048	0.575
MOD_GlcNHglycan	94	97	PF01048	0.574
MOD_GSK3_1	177	184	PF00069	0.596
MOD_GSK3_1	194	201	PF00069	0.656
MOD_GSK3_1	231	238	PF00069	0.642
MOD_GSK3_1	34	41	PF00069	0.624
MOD_N-GLC_1	38	43	PF02516	0.749
MOD_NEK2_1	23	28	PF00069	0.468
MOD_NEK2_1	78	83	PF00069	0.340
MOD_NEK2_2	163	168	PF00069	0.588
MOD_OFUCOSY	104	110	PF10250	0.636
MOD_OFUCOSY	175	181	PF10250	0.348
MOD_PIKK_1	78	84	PF00454	0.313
MOD_PKA_1	13	19	PF00069	0.448
MOD_PKA_2	12	18	PF00069	0.605
MOD_PKA_2	47	53	PF00069	0.464
MOD_PKB_1	11	19	PF00069	0.460
MOD_Plk_4	126	132	PF00069	0.428
MOD_Plk_4	231	237	PF00069	0.637
MOD_Plk_4	80	86	PF00069	0.452
MOD_ProDKin_1	203	209	PF00069	0.623
MOD_SUMO_rev_2	37	46	PF00179	0.639
TRG_DiLeu_BaLyEn_6	247	252	PF01217	0.663
TRG_ENDOCYTIC_2	164	167	PF00928	0.691
TRG_ENDOCYTIC_2	249	252	PF00928	0.664
TRG_ER_diArg_1	100	103	PF00400	0.390
TRG_ER_diArg_1	11	14	PF00400	0.488
TRG_Pf-PMV_PEXEL_1	185	189	PF00026	0.473

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P5W2	Leptomonas seymouri	45%	100%
A0A3S7X7R5	Leishmania donovani	86%	100%
A4HAN6	Leishmania braziliensis	67%	100%
A4I9S9	Leishmania infantum	86%	100%
Q4Q386	Leishmania major	82%	100%