Ribosome maturation protein SDO1

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

Shwachman-Bodian-Diamond syndrome (SBDS) protein/SBDS protein C-terminal domain containing protein, putative

Species:

Leishmania mexicana

UniProt:

E9B4T2_LEIMU

TriTrypDb:

LmxM.33.1110

Length:

537

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B4T2

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B4T2

Function

Biological processes
Term	Name	Level	Count
GO:0009987	cellular process	1	6
GO:0022613	ribonucleoprotein complex biogenesis	4	6
GO:0042254	ribosome biogenesis	5	6
GO:0044085	cellular component biogenesis	3	6
GO:0071840	cellular component organization or biogenesis	2	6

Could not find GO molecular_function term for this entry.

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	259	263	PF00656	0.619
CLV_C14_Caspase3-7	287	291	PF00656	0.565
CLV_C14_Caspase3-7	309	313	PF00656	0.534
CLV_C14_Caspase3-7	374	378	PF00656	0.713
CLV_NRD_NRD_1	12	14	PF00675	0.622
CLV_NRD_NRD_1	292	294	PF00675	0.792
CLV_NRD_NRD_1	422	424	PF00675	0.650
CLV_NRD_NRD_1	442	444	PF00675	0.732
CLV_NRD_NRD_1	466	468	PF00675	0.743
CLV_NRD_NRD_1	499	501	PF00675	0.717
CLV_PCSK_KEX2_1	12	14	PF00082	0.622
CLV_PCSK_KEX2_1	292	294	PF00082	0.792
CLV_PCSK_KEX2_1	422	424	PF00082	0.708
CLV_PCSK_PC1ET2_1	422	424	PF00082	0.708
CLV_PCSK_SKI1_1	155	159	PF00082	0.387
CLV_PCSK_SKI1_1	468	472	PF00082	0.753
CLV_PCSK_SKI1_1	71	75	PF00082	0.220
CLV_PCSK_SKI1_1	88	92	PF00082	0.377
DEG_SPOP_SBC_1	297	301	PF00917	0.699
DOC_CYCLIN_yClb5_NLxxxL_5	227	236	PF00134	0.541
DOC_MAPK_gen_1	12	19	PF00069	0.586
DOC_MAPK_gen_1	154	160	PF00069	0.577
DOC_MAPK_gen_1	21	31	PF00069	0.497
DOC_MAPK_MEF2A_6	24	31	PF00069	0.577
DOC_USP7_MATH_1	139	143	PF00917	0.558
DOC_USP7_MATH_1	245	249	PF00917	0.587
DOC_USP7_MATH_1	279	283	PF00917	0.622
DOC_USP7_MATH_1	296	300	PF00917	0.707
DOC_USP7_MATH_1	434	438	PF00917	0.712
DOC_USP7_UBL2_3	24	28	PF12436	0.556
DOC_USP7_UBL2_3	420	424	PF12436	0.615
DOC_USP7_UBL2_3	464	468	PF12436	0.768
DOC_USP7_UBL2_3	501	505	PF12436	0.707
LIG_14-3-3_CanoR_1	180	189	PF00244	0.558
LIG_BIR_II_1	1	5	PF00653	0.677
LIG_FHA_1	102	108	PF00498	0.600
LIG_FHA_2	181	187	PF00498	0.581
LIG_FHA_2	285	291	PF00498	0.565
LIG_FHA_2	80	86	PF00498	0.629
LIG_LIR_Gen_1	56	67	PF02991	0.577
LIG_LIR_Nem_3	108	114	PF02991	0.519
LIG_LIR_Nem_3	56	62	PF02991	0.577
LIG_NRBOX	159	165	PF00104	0.577
LIG_SH2_STAT5	66	69	PF00017	0.577
LIG_SH3_3	127	133	PF00018	0.584
LIG_SH3_3	201	207	PF00018	0.396
LIG_SUMO_SIM_anti_2	113	119	PF11976	0.577
LIG_SUMO_SIM_anti_2	15	21	PF11976	0.447
LIG_SUMO_SIM_anti_2	223	229	PF11976	0.370
LIG_TRAF2_1	282	285	PF00917	0.641
LIG_TRAF2_1	492	495	PF00917	0.728
LIG_TRAF2_1	99	102	PF00917	0.582
LIG_UBA3_1	232	241	PF00899	0.556
MOD_CK1_1	270	276	PF00069	0.464
MOD_CK1_1	299	305	PF00069	0.765
MOD_CK1_1	363	369	PF00069	0.620
MOD_CK1_1	40	46	PF00069	0.577
MOD_CK2_1	180	186	PF00069	0.577
MOD_CK2_1	279	285	PF00069	0.564
MOD_CK2_1	335	341	PF00069	0.776
MOD_CK2_1	40	46	PF00069	0.577
MOD_CK2_1	489	495	PF00069	0.709
MOD_CK2_1	66	72	PF00069	0.595
MOD_CK2_1	79	85	PF00069	0.514
MOD_Cter_Amidation	420	423	PF01082	0.782
MOD_Cter_Amidation	441	444	PF01082	0.729
MOD_Cter_Amidation	462	465	PF01082	0.758
MOD_GlcNHglycan	1	4	PF01048	0.691
MOD_GlcNHglycan	245	248	PF01048	0.609
MOD_GlcNHglycan	268	272	PF01048	0.453
MOD_GlcNHglycan	301	304	PF01048	0.729
MOD_GlcNHglycan	320	323	PF01048	0.527
MOD_GlcNHglycan	331	334	PF01048	0.627
MOD_GlcNHglycan	383	386	PF01048	0.611
MOD_GlcNHglycan	42	45	PF01048	0.381
MOD_GlcNHglycan	427	430	PF01048	0.784
MOD_GSK3_1	202	209	PF00069	0.633
MOD_GSK3_1	216	223	PF00069	0.540
MOD_GSK3_1	284	291	PF00069	0.778
MOD_GSK3_1	340	347	PF00069	0.554
MOD_N-GLC_1	210	215	PF02516	0.607
MOD_N-GLC_1	216	221	PF02516	0.527
MOD_N-GLC_1	306	311	PF02516	0.539
MOD_N-GLC_1	329	334	PF02516	0.777
MOD_N-GLC_1	363	368	PF02516	0.708
MOD_N-GLC_1	425	430	PF02516	0.782
MOD_NEK2_1	149	154	PF00069	0.587
MOD_NEK2_1	220	225	PF00069	0.397
MOD_NEK2_1	267	272	PF00069	0.458
MOD_PIKK_1	124	130	PF00454	0.514
MOD_PIKK_1	351	357	PF00454	0.559
MOD_PIKK_1	434	440	PF00454	0.776
MOD_PIKK_1	7	13	PF00454	0.636
MOD_PKA_1	12	18	PF00069	0.596
MOD_PKA_1	424	430	PF00069	0.563
MOD_PKA_2	12	18	PF00069	0.630
MOD_PKA_2	179	185	PF00069	0.543
MOD_PKA_2	20	26	PF00069	0.534
MOD_PKA_2	360	366	PF00069	0.645
MOD_Plk_1	149	155	PF00069	0.545
MOD_Plk_1	267	273	PF00069	0.470
MOD_Plk_2-3	487	493	PF00069	0.532
MOD_Plk_2-3	79	85	PF00069	0.431
MOD_Plk_4	220	226	PF00069	0.446
MOD_SUMO_for_1	240	243	PF00179	0.424
MOD_SUMO_for_1	27	30	PF00179	0.556
MOD_SUMO_for_1	481	484	PF00179	0.540
MOD_SUMO_rev_2	69	76	PF00179	0.420
TRG_NES_CRM1_1	138	150	PF08389	0.577
TRG_NES_CRM1_1	389	400	PF08389	0.723
TRG_NLS_MonoCore_2	421	426	PF00514	0.720
TRG_NLS_MonoExtC_3	463	468	PF00514	0.766
TRG_NLS_MonoExtN_4	420	427	PF00514	0.779
TRG_NLS_MonoExtN_4	462	468	PF00514	0.769

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3Q8IFC9	Leishmania donovani	88%	100%
A4HAM9	Leishmania braziliensis	72%	99%
A4I9S1	Leishmania infantum	88%	100%
Q4Q394	Leishmania major	86%	100%