LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania mexicana
UniProt:
E9B4R4_LEIMU
TriTrypDb:
LmxM.33.0930
Length:
107

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 10
NetGPI no yes: 0, no: 10
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B4R4
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B4R4

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 101 103 PF00675 0.509
CLV_PCSK_SKI1_1 72 76 PF00082 0.605
DOC_MAPK_gen_1 71 77 PF00069 0.574
DOC_WW_Pin1_4 49 54 PF00397 0.599
LIG_BRCT_BRCA1_1 15 19 PF00533 0.546
LIG_BRCT_BRCA1_2 15 21 PF00533 0.573
LIG_FHA_2 50 56 PF00498 0.509
LIG_LIR_Gen_1 60 70 PF02991 0.439
LIG_LIR_Gen_1 73 81 PF02991 0.565
LIG_LIR_Gen_1 87 97 PF02991 0.606
LIG_LIR_Nem_3 16 22 PF02991 0.498
LIG_LIR_Nem_3 60 65 PF02991 0.440
LIG_LIR_Nem_3 73 77 PF02991 0.572
LIG_LIR_Nem_3 78 84 PF02991 0.558
LIG_SH2_SRC 22 25 PF00017 0.553
LIG_TRAF2_1 52 55 PF00917 0.566
LIG_TRFH_1 49 53 PF08558 0.600
MOD_CDK_SPxxK_3 49 56 PF00069 0.582
MOD_CK2_1 49 55 PF00069 0.500
MOD_CK2_1 76 82 PF00069 0.563
MOD_NEK2_1 1 6 PF00069 0.680
MOD_NEK2_1 75 80 PF00069 0.562
MOD_NMyristoyl 1 7 PF02799 0.554
MOD_Plk_4 76 82 PF00069 0.563
MOD_ProDKin_1 49 55 PF00069 0.587
MOD_SUMO_for_1 70 73 PF00179 0.596
TRG_DiLeu_BaEn_4 60 66 PF01217 0.429
TRG_ENDOCYTIC_2 66 69 PF00928 0.464
TRG_ENDOCYTIC_2 89 92 PF00928 0.517
TRG_ER_diArg_1 26 29 PF00400 0.518

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0S4J0J3 Bodo saltans 46% 100%
A0A1X0P995 Trypanosomatidae 58% 100%
A0A3S7X7N4 Leishmania donovani 100% 100%
A0A422N277 Trypanosoma rangeli 58% 100%
A4HAK9 Leishmania braziliensis 92% 100%
A4I9Q0 Leishmania infantum 100% 100%
C6K3V4 Leptomonas seymouri 78% 100%
C9ZMY9 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 54% 98%
Q4Q3B2 Leishmania major 99% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS