Mitochondrial RNA binding complex 1 subunit

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9B4P1_LEIMU

TriTrypDb:

LmxM.33.0710

Length:

769

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 7
NetGPI	no	yes: 0, no: 7

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B4P1

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B4P1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	583	587	PF00656	0.473
CLV_NRD_NRD_1	251	253	PF00675	0.451
CLV_NRD_NRD_1	463	465	PF00675	0.462
CLV_NRD_NRD_1	509	511	PF00675	0.588
CLV_NRD_NRD_1	525	527	PF00675	0.320
CLV_PCSK_KEX2_1	251	253	PF00082	0.451
CLV_PCSK_KEX2_1	509	511	PF00082	0.503
CLV_PCSK_KEX2_1	605	607	PF00082	0.414
CLV_PCSK_KEX2_1	693	695	PF00082	0.478
CLV_PCSK_KEX2_1	758	760	PF00082	0.651
CLV_PCSK_PC1ET2_1	509	511	PF00082	0.503
CLV_PCSK_PC1ET2_1	605	607	PF00082	0.414
CLV_PCSK_PC1ET2_1	693	695	PF00082	0.478
CLV_PCSK_PC1ET2_1	758	760	PF00082	0.628
CLV_PCSK_SKI1_1	216	220	PF00082	0.433
CLV_PCSK_SKI1_1	393	397	PF00082	0.539
CLV_PCSK_SKI1_1	413	417	PF00082	0.419
CLV_PCSK_SKI1_1	434	438	PF00082	0.449
CLV_PCSK_SKI1_1	465	469	PF00082	0.395
CLV_PCSK_SKI1_1	621	625	PF00082	0.598
CLV_PCSK_SKI1_1	676	680	PF00082	0.424
CLV_PCSK_SKI1_1	719	723	PF00082	0.442
DEG_APCC_DBOX_1	355	363	PF00400	0.375
DEG_APCC_DBOX_1	718	726	PF00400	0.460
DEG_SCF_FBW7_2	285	291	PF00400	0.429
DEG_SCF_FBW7_2	528	535	PF00400	0.422
DEG_SPOP_SBC_1	585	589	PF00917	0.468
DOC_CKS1_1	285	290	PF01111	0.434
DOC_CKS1_1	70	75	PF01111	0.451
DOC_CYCLIN_RxL_1	523	531	PF00134	0.439
DOC_CYCLIN_RxL_1	713	726	PF00134	0.442
DOC_MAPK_gen_1	434	443	PF00069	0.599
DOC_MAPK_gen_1	509	520	PF00069	0.558
DOC_MAPK_gen_1	564	572	PF00069	0.482
DOC_MAPK_gen_1	742	751	PF00069	0.593
DOC_MAPK_MEF2A_6	304	313	PF00069	0.296
DOC_MAPK_MEF2A_6	479	487	PF00069	0.363
DOC_PP4_FxxP_1	94	97	PF00568	0.438
DOC_USP7_MATH_1	182	186	PF00917	0.495
DOC_USP7_MATH_1	257	261	PF00917	0.604
DOC_USP7_MATH_1	271	275	PF00917	0.301
DOC_USP7_MATH_1	314	318	PF00917	0.450
DOC_USP7_MATH_1	397	401	PF00917	0.469
DOC_USP7_MATH_1	547	551	PF00917	0.525
DOC_USP7_MATH_1	636	640	PF00917	0.439
DOC_USP7_MATH_1	86	90	PF00917	0.454
DOC_USP7_UBL2_3	523	527	PF12436	0.273
DOC_USP7_UBL2_3	753	757	PF12436	0.644
DOC_WW_Pin1_4	284	289	PF00397	0.501
DOC_WW_Pin1_4	376	381	PF00397	0.423
DOC_WW_Pin1_4	509	514	PF00397	0.465
DOC_WW_Pin1_4	528	533	PF00397	0.428
DOC_WW_Pin1_4	56	61	PF00397	0.582
DOC_WW_Pin1_4	69	74	PF00397	0.354
DOC_WW_Pin1_4	729	734	PF00397	0.567
DOC_WW_Pin1_4	764	769	PF00397	0.544
LIG_14-3-3_CanoR_1	111	119	PF00244	0.411
LIG_14-3-3_CanoR_1	127	137	PF00244	0.467
LIG_14-3-3_CanoR_1	183	191	PF00244	0.439
LIG_14-3-3_CanoR_1	434	443	PF00244	0.462
LIG_14-3-3_CanoR_1	470	476	PF00244	0.438
LIG_14-3-3_CanoR_1	50	60	PF00244	0.378
LIG_14-3-3_CanoR_1	566	570	PF00244	0.437
LIG_14-3-3_CanoR_1	581	585	PF00244	0.366
LIG_14-3-3_CanoR_1	621	630	PF00244	0.476
LIG_14-3-3_CanoR_1	694	698	PF00244	0.454
LIG_14-3-3_CanoR_1	719	725	PF00244	0.419
LIG_14-3-3_CanoR_1	759	766	PF00244	0.626
LIG_Actin_WH2_2	459	475	PF00022	0.425
LIG_BRCT_BRCA1_1	207	211	PF00533	0.431
LIG_deltaCOP1_diTrp_1	294	302	PF00928	0.419
LIG_FHA_1	13	19	PF00498	0.522
LIG_FHA_1	162	168	PF00498	0.410
LIG_FHA_1	218	224	PF00498	0.554
LIG_FHA_1	242	248	PF00498	0.394
LIG_FHA_1	25	31	PF00498	0.557
LIG_FHA_1	327	333	PF00498	0.411
LIG_FHA_1	342	348	PF00498	0.436
LIG_FHA_1	513	519	PF00498	0.462
LIG_FHA_1	529	535	PF00498	0.542
LIG_FHA_1	587	593	PF00498	0.338
LIG_FHA_1	70	76	PF00498	0.446
LIG_FHA_2	118	124	PF00498	0.311
LIG_FHA_2	134	140	PF00498	0.530
LIG_FHA_2	220	226	PF00498	0.466
LIG_FHA_2	285	291	PF00498	0.436
LIG_FHA_2	5	11	PF00498	0.471
LIG_FHA_2	586	592	PF00498	0.374
LIG_GBD_Chelix_1	75	83	PF00786	0.401
LIG_LIR_Gen_1	208	219	PF02991	0.431
LIG_LIR_Gen_1	669	679	PF02991	0.388
LIG_LIR_Gen_1	701	708	PF02991	0.427
LIG_LIR_Gen_1	761	768	PF02991	0.624
LIG_LIR_Nem_3	136	140	PF02991	0.494
LIG_LIR_Nem_3	208	214	PF02991	0.437
LIG_LIR_Nem_3	669	674	PF02991	0.408
LIG_LIR_Nem_3	701	706	PF02991	0.429
LIG_LIR_Nem_3	761	766	PF02991	0.625
LIG_NRBOX	171	177	PF00104	0.450
LIG_NRBOX	553	559	PF00104	0.283
LIG_NRBOX	660	666	PF00104	0.419
LIG_NRBOX	720	726	PF00104	0.459
LIG_PAM2_1	439	451	PF00658	0.420
LIG_PCNA_yPIPBox_3	150	158	PF02747	0.494
LIG_Pex14_1	703	707	PF04695	0.339
LIG_Pex14_2	94	98	PF04695	0.437
LIG_REV1ctd_RIR_1	299	308	PF16727	0.402
LIG_REV1ctd_RIR_1	676	684	PF16727	0.431
LIG_SH2_CRK	671	675	PF00017	0.412
LIG_SH2_GRB2like	707	710	PF00017	0.303
LIG_SH2_NCK_1	671	675	PF00017	0.412
LIG_SH2_SRC	238	241	PF00017	0.291
LIG_SH2_STAP1	66	70	PF00017	0.445
LIG_SH2_STAT3	369	372	PF00017	0.390
LIG_SH2_STAT5	238	241	PF00017	0.359
LIG_SH2_STAT5	292	295	PF00017	0.397
LIG_SH2_STAT5	369	372	PF00017	0.382
LIG_SH2_STAT5	448	451	PF00017	0.428
LIG_SH2_STAT5	707	710	PF00017	0.368
LIG_SH2_STAT5	740	743	PF00017	0.454
LIG_SH3_3	282	288	PF00018	0.446
LIG_Sin3_3	307	314	PF02671	0.260
LIG_SUMO_SIM_anti_2	139	144	PF11976	0.474
LIG_SUMO_SIM_anti_2	171	177	PF11976	0.324
LIG_SUMO_SIM_anti_2	244	249	PF11976	0.318
LIG_SUMO_SIM_anti_2	550	559	PF11976	0.431
LIG_SUMO_SIM_anti_2	586	597	PF11976	0.441
LIG_SUMO_SIM_anti_2	720	728	PF11976	0.473
LIG_SUMO_SIM_par_1	171	177	PF11976	0.440
LIG_SUMO_SIM_par_1	486	492	PF11976	0.255
LIG_SUMO_SIM_par_1	550	559	PF11976	0.444
LIG_SUMO_SIM_par_1	586	597	PF11976	0.439
LIG_SUMO_SIM_par_1	720	728	PF11976	0.473
LIG_TRAF2_1	303	306	PF00917	0.388
LIG_TRAF2_1	638	641	PF00917	0.437
LIG_UBA3_1	17	22	PF00899	0.553
LIG_UBA3_1	431	437	PF00899	0.449
LIG_WRC_WIRS_1	5	10	PF05994	0.474
LIG_WRC_WIRS_1	595	600	PF05994	0.451
MOD_CDK_SPK_2	509	514	PF00069	0.465
MOD_CK1_1	114	120	PF00069	0.443
MOD_CK1_1	129	135	PF00069	0.287
MOD_CK1_1	241	247	PF00069	0.398
MOD_CK1_1	258	264	PF00069	0.525
MOD_CK1_1	300	306	PF00069	0.501
MOD_CK1_1	31	37	PF00069	0.502
MOD_CK1_1	360	366	PF00069	0.532
MOD_CK1_1	474	480	PF00069	0.545
MOD_CK1_1	54	60	PF00069	0.504
MOD_CK1_1	559	565	PF00069	0.508
MOD_CK1_1	587	593	PF00069	0.431
MOD_CK1_1	669	675	PF00069	0.480
MOD_CK1_1	71	77	PF00069	0.334
MOD_CK1_1	720	726	PF00069	0.459
MOD_CK1_1	761	767	PF00069	0.669
MOD_CK2_1	117	123	PF00069	0.303
MOD_CK2_1	138	144	PF00069	0.517
MOD_CK2_1	219	225	PF00069	0.432
MOD_CK2_1	260	266	PF00069	0.553
MOD_CK2_1	280	286	PF00069	0.488
MOD_CK2_1	300	306	PF00069	0.343
MOD_CK2_1	32	38	PF00069	0.500
MOD_CK2_1	322	328	PF00069	0.478
MOD_CK2_1	42	48	PF00069	0.620
MOD_CK2_1	635	641	PF00069	0.575
MOD_Cter_Amidation	603	606	PF01082	0.388
MOD_DYRK1A_RPxSP_1	731	735	PF00069	0.569
MOD_GlcNHglycan	161	164	PF01048	0.416
MOD_GlcNHglycan	2	5	PF01048	0.407
MOD_GlcNHglycan	235	238	PF01048	0.574
MOD_GlcNHglycan	316	319	PF01048	0.587
MOD_GlcNHglycan	323	327	PF01048	0.390
MOD_GlcNHglycan	373	376	PF01048	0.462
MOD_GlcNHglycan	38	42	PF01048	0.560
MOD_GlcNHglycan	43	47	PF01048	0.476
MOD_GlcNHglycan	443	446	PF01048	0.448
MOD_GlcNHglycan	624	627	PF01048	0.546
MOD_GlcNHglycan	687	690	PF01048	0.438
MOD_GlcNHglycan	700	703	PF01048	0.285
MOD_GSK3_1	106	113	PF00069	0.521
MOD_GSK3_1	129	136	PF00069	0.438
MOD_GSK3_1	24	31	PF00069	0.522
MOD_GSK3_1	251	258	PF00069	0.543
MOD_GSK3_1	280	287	PF00069	0.518
MOD_GSK3_1	305	312	PF00069	0.538
MOD_GSK3_1	322	329	PF00069	0.325
MOD_GSK3_1	357	364	PF00069	0.452
MOD_GSK3_1	393	400	PF00069	0.459
MOD_GSK3_1	435	442	PF00069	0.497
MOD_GSK3_1	52	59	PF00069	0.535
MOD_GSK3_1	580	587	PF00069	0.480
MOD_GSK3_1	594	601	PF00069	0.306
MOD_GSK3_1	713	720	PF00069	0.481
MOD_GSK3_1	725	732	PF00069	0.459
MOD_GSK3_1	747	754	PF00069	0.495
MOD_N-GLC_1	547	552	PF02516	0.454
MOD_N-GLC_1	698	703	PF02516	0.437
MOD_NEK2_1	106	111	PF00069	0.611
MOD_NEK2_1	12	17	PF00069	0.508
MOD_NEK2_1	126	131	PF00069	0.464
MOD_NEK2_1	138	143	PF00069	0.333
MOD_NEK2_1	217	222	PF00069	0.432
MOD_NEK2_1	280	285	PF00069	0.507
MOD_NEK2_1	297	302	PF00069	0.398
MOD_NEK2_1	309	314	PF00069	0.329
MOD_NEK2_1	336	341	PF00069	0.472
MOD_NEK2_1	342	347	PF00069	0.420
MOD_NEK2_1	37	42	PF00069	0.492
MOD_NEK2_1	371	376	PF00069	0.453
MOD_NEK2_1	441	446	PF00069	0.465
MOD_NEK2_1	52	57	PF00069	0.332
MOD_NEK2_1	539	544	PF00069	0.474
MOD_NEK2_1	558	563	PF00069	0.251
MOD_NEK2_1	584	589	PF00069	0.497
MOD_NEK2_1	594	599	PF00069	0.355
MOD_NEK2_1	724	729	PF00069	0.528
MOD_NEK2_2	747	752	PF00069	0.476
MOD_PIKK_1	111	117	PF00454	0.509
MOD_PIKK_1	182	188	PF00454	0.446
MOD_PIKK_1	280	286	PF00454	0.538
MOD_PIKK_1	357	363	PF00454	0.474
MOD_PIKK_1	435	441	PF00454	0.621
MOD_PIKK_1	512	518	PF00454	0.377
MOD_PIKK_1	598	604	PF00454	0.426
MOD_PIKK_1	636	642	PF00454	0.439
MOD_PIKK_1	725	731	PF00454	0.487
MOD_PK_1	713	719	PF00069	0.388
MOD_PKA_1	251	257	PF00069	0.480
MOD_PKA_1	693	699	PF00069	0.428
MOD_PKA_1	758	764	PF00069	0.616
MOD_PKA_2	110	116	PF00069	0.339
MOD_PKA_2	126	132	PF00069	0.473
MOD_PKA_2	182	188	PF00069	0.467
MOD_PKA_2	251	257	PF00069	0.520
MOD_PKA_2	565	571	PF00069	0.439
MOD_PKA_2	580	586	PF00069	0.316
MOD_PKA_2	669	675	PF00069	0.480
MOD_PKA_2	693	699	PF00069	0.428
MOD_PKA_2	758	764	PF00069	0.588
MOD_Plk_1	12	18	PF00069	0.542
MOD_Plk_1	138	144	PF00069	0.453
MOD_Plk_1	224	230	PF00069	0.374
MOD_Plk_1	241	247	PF00069	0.391
MOD_Plk_1	305	311	PF00069	0.508
MOD_Plk_1	357	363	PF00069	0.453
MOD_Plk_1	439	445	PF00069	0.475
MOD_Plk_1	656	662	PF00069	0.409
MOD_Plk_1	698	704	PF00069	0.467
MOD_Plk_1	713	719	PF00069	0.301
MOD_Plk_1	761	767	PF00069	0.628
MOD_Plk_2-3	286	292	PF00069	0.426
MOD_Plk_4	13	19	PF00069	0.595
MOD_Plk_4	133	139	PF00069	0.453
MOD_Plk_4	219	225	PF00069	0.455
MOD_Plk_4	297	303	PF00069	0.361
MOD_Plk_4	305	311	PF00069	0.409
MOD_Plk_4	342	348	PF00069	0.380
MOD_Plk_4	565	571	PF00069	0.489
MOD_Plk_4	693	699	PF00069	0.430
MOD_Plk_4	71	77	PF00069	0.323
MOD_Plk_4	720	726	PF00069	0.459
MOD_ProDKin_1	284	290	PF00069	0.494
MOD_ProDKin_1	376	382	PF00069	0.416
MOD_ProDKin_1	509	515	PF00069	0.459
MOD_ProDKin_1	528	534	PF00069	0.422
MOD_ProDKin_1	56	62	PF00069	0.579
MOD_ProDKin_1	69	75	PF00069	0.349
MOD_ProDKin_1	729	735	PF00069	0.566
MOD_SUMO_rev_2	144	153	PF00179	0.483
TRG_DiLeu_BaEn_1	152	157	PF01217	0.446
TRG_DiLeu_BaEn_1	168	173	PF01217	0.341
TRG_DiLeu_BaEn_1	305	310	PF01217	0.416
TRG_DiLeu_BaEn_1	481	486	PF01217	0.431
TRG_DiLeu_BaEn_1	535	540	PF01217	0.464
TRG_DiLeu_BaEn_1	657	662	PF01217	0.411
TRG_DiLeu_BaLyEn_6	529	534	PF01217	0.427
TRG_DiLeu_BaLyEn_6	660	665	PF01217	0.410
TRG_ENDOCYTIC_2	671	674	PF00928	0.423
TRG_ER_diArg_1	276	279	PF00400	0.473
TRG_ER_FFAT_1	59	71	PF00635	0.486
TRG_NES_CRM1_1	139	152	PF08389	0.473
TRG_NLS_Bipartite_1	509	530	PF00514	0.282
TRG_NLS_MonoExtC_3	508	513	PF00514	0.491
TRG_NLS_MonoExtC_3	756	762	PF00514	0.584
TRG_NLS_MonoExtN_4	523	530	PF00514	0.273
TRG_NLS_MonoExtN_4	755	761	PF00514	0.621
TRG_Pf-PMV_PEXEL_1	165	169	PF00026	0.308
TRG_Pf-PMV_PEXEL_1	197	201	PF00026	0.464
TRG_Pf-PMV_PEXEL_1	503	507	PF00026	0.438

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P3F0	Leptomonas seymouri	33%	84%
A0A3Q8IKR6	Leishmania donovani	92%	100%
A4HAI0	Leishmania braziliensis	81%	100%
A4IAP1	Leishmania infantum	92%	100%
C9ZN12	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	25%	92%
Q4Q3D5	Leishmania major	91%	100%