Splicing factor ptsr1 interacting protein,putative

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

splicing factor ptsr1 interacting protein, putative

Species:

Leishmania mexicana

UniProt:

E9B4L8_LEIMU

TriTrypDb:

LmxM.33.0495

Length:

257

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Cellular components
Term	Name	Level	Count
GO:0005654	nucleoplasm	2	1
GO:0110165	cellular anatomical entity	1	1

Expansion

Sequence features

E9B4L8

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B4L8

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	206	210	PF00656	0.650
CLV_NRD_NRD_1	137	139	PF00675	0.844
CLV_NRD_NRD_1	152	154	PF00675	0.660
CLV_NRD_NRD_1	164	166	PF00675	0.673
CLV_NRD_NRD_1	173	175	PF00675	0.683
CLV_NRD_NRD_1	200	202	PF00675	0.732
CLV_NRD_NRD_1	211	213	PF00675	0.738
CLV_NRD_NRD_1	224	226	PF00675	0.762
CLV_NRD_NRD_1	227	229	PF00675	0.804
CLV_NRD_NRD_1	243	245	PF00675	0.630
CLV_NRD_NRD_1	250	252	PF00675	0.643
CLV_PCSK_FUR_1	162	166	PF00082	0.714
CLV_PCSK_FUR_1	197	201	PF00082	0.738
CLV_PCSK_FUR_1	225	229	PF00082	0.722
CLV_PCSK_KEX2_1	137	139	PF00082	0.844
CLV_PCSK_KEX2_1	152	154	PF00082	0.660
CLV_PCSK_KEX2_1	162	164	PF00082	0.633
CLV_PCSK_KEX2_1	173	175	PF00082	0.734
CLV_PCSK_KEX2_1	197	199	PF00082	0.736
CLV_PCSK_KEX2_1	200	202	PF00082	0.731
CLV_PCSK_KEX2_1	211	213	PF00082	0.737
CLV_PCSK_KEX2_1	224	226	PF00082	0.762
CLV_PCSK_KEX2_1	227	229	PF00082	0.804
CLV_PCSK_KEX2_1	243	245	PF00082	0.630
CLV_PCSK_KEX2_1	249	251	PF00082	0.635
CLV_PCSK_SKI1_1	42	46	PF00082	0.674
DEG_Nend_UBRbox_2	1	3	PF02207	0.676
DOC_MAPK_DCC_7	51	61	PF00069	0.790
DOC_PP4_MxPP_1	55	58	PF00568	0.783
DOC_USP7_UBL2_3	86	90	PF12436	0.797
DOC_WW_Pin1_4	109	114	PF00397	0.821
LIG_14-3-3_CanoR_1	178	187	PF00244	0.744
LIG_deltaCOP1_diTrp_1	20	25	PF00928	0.501
LIG_FHA_2	110	116	PF00498	0.555
LIG_FHA_2	127	133	PF00498	0.819
LIG_FHA_2	92	98	PF00498	0.786
LIG_LIR_Gen_1	23	33	PF02991	0.459
LIG_LIR_Gen_1	95	102	PF02991	0.782
LIG_LIR_Nem_3	20	24	PF02991	0.384
LIG_LIR_Nem_3	40	44	PF02991	0.322
LIG_LIR_Nem_3	7	11	PF02991	0.669
LIG_LIR_Nem_3	95	101	PF02991	0.780
LIG_NRP_CendR_1	256	257	PF00754	0.702
LIG_Pex14_1	21	25	PF04695	0.495
LIG_SH2_CRK	41	45	PF00017	0.503
LIG_SH2_CRK	8	12	PF00017	0.710
LIG_SH2_NCK_1	8	12	PF00017	0.613
LIG_SH2_SRC	8	11	PF00017	0.715
LIG_SH2_STAT5	24	27	PF00017	0.453
LIG_SH3_3	50	56	PF00018	0.777
LIG_TRAF2_1	168	171	PF00917	0.693
LIG_TRAF2_1	218	221	PF00917	0.822
LIG_WW_1	5	8	PF00397	0.646
LIG_WW_2	57	60	PF00397	0.800
MOD_CDK_SPK_2	109	114	PF00069	0.821
MOD_CK1_1	100	106	PF00069	0.677
MOD_CK1_1	108	114	PF00069	0.731
MOD_CK1_1	182	188	PF00069	0.782
MOD_CK1_1	190	196	PF00069	0.696
MOD_CK1_1	219	225	PF00069	0.785
MOD_CK1_1	232	238	PF00069	0.591
MOD_CK2_1	165	171	PF00069	0.816
MOD_CK2_1	215	221	PF00069	0.825
MOD_CK2_1	89	95	PF00069	0.668
MOD_Cter_Amidation	209	212	PF01082	0.553
MOD_GlcNHglycan	107	110	PF01048	0.731
MOD_GlcNHglycan	192	195	PF01048	0.775
MOD_GlcNHglycan	201	204	PF01048	0.676
MOD_GlcNHglycan	231	234	PF01048	0.791
MOD_GlcNHglycan	71	74	PF01048	0.742
MOD_GSK3_1	104	111	PF00069	0.712
MOD_GSK3_1	133	140	PF00069	0.822
MOD_GSK3_1	178	185	PF00069	0.746
MOD_GSK3_1	188	195	PF00069	0.748
MOD_GSK3_1	211	218	PF00069	0.830
MOD_GSK3_1	227	234	PF00069	0.543
MOD_GSK3_1	61	68	PF00069	0.806
MOD_GSK3_1	96	103	PF00069	0.660
MOD_NEK2_1	101	106	PF00069	0.689
MOD_PIKK_1	63	69	PF00454	0.820
MOD_PKA_1	137	143	PF00069	0.825
MOD_PKA_1	199	205	PF00069	0.727
MOD_PKA_1	211	217	PF00069	0.732
MOD_PKA_1	227	233	PF00069	0.545
MOD_PKA_2	133	139	PF00069	0.823
MOD_PKA_2	156	162	PF00069	0.811
MOD_PKA_2	182	188	PF00069	0.738
MOD_PKA_2	199	205	PF00069	0.757
MOD_PKA_2	210	216	PF00069	0.729
MOD_PKA_2	227	233	PF00069	0.529
MOD_PKB_1	163	171	PF00069	0.771
MOD_PKB_1	176	184	PF00069	0.655
MOD_PKB_1	197	205	PF00069	0.730
MOD_PKB_1	225	233	PF00069	0.808
MOD_Plk_1	96	102	PF00069	0.663
MOD_Plk_2-3	156	162	PF00069	0.811
MOD_Plk_4	97	103	PF00069	0.727
MOD_ProDKin_1	109	115	PF00069	0.823
MOD_SUMO_rev_2	82	88	PF00179	0.790
TRG_ENDOCYTIC_2	27	30	PF00928	0.317
TRG_ENDOCYTIC_2	41	44	PF00928	0.409
TRG_ENDOCYTIC_2	8	11	PF00928	0.716
TRG_ER_diArg_1	152	155	PF00400	0.770
TRG_ER_diArg_1	162	165	PF00400	0.679
TRG_ER_diArg_1	173	176	PF00400	0.731
TRG_ER_diArg_1	197	200	PF00400	0.734
TRG_ER_diArg_1	224	226	PF00400	0.722
TRG_ER_diArg_1	248	251	PF00400	0.627
TRG_ER_diArg_1	255	257	PF00400	0.690

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1HR54	Leptomonas seymouri	46%	100%
A0A3Q8II79	Leishmania donovani	97%	100%
A4I9M0	Leishmania infantum	97%	100%
Q4Q3F8	Leishmania major	95%	100%