LeishMANIAdb
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Protein kinase

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Protein kinase
Gene product:
hypothetical protein, unknown function
Species:
Leishmania mexicana
UniProt:
E9B4L3_LEIMU
TriTrypDb:
LmxM.33.0450
Length:
886

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 5
NetGPI no yes: 0, no: 5
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B4L3
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B4L3

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 124 128 PF00656 0.773
CLV_C14_Caspase3-7 51 55 PF00656 0.777
CLV_C14_Caspase3-7 667 671 PF00656 0.820
CLV_NRD_NRD_1 114 116 PF00675 0.862
CLV_NRD_NRD_1 400 402 PF00675 0.772
CLV_NRD_NRD_1 681 683 PF00675 0.851
CLV_NRD_NRD_1 722 724 PF00675 0.820
CLV_NRD_NRD_1 878 880 PF00675 0.795
CLV_PCSK_KEX2_1 114 116 PF00082 0.862
CLV_PCSK_KEX2_1 189 191 PF00082 0.747
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Homologs

ProteinTaxonomySequence identityCoverage
A0A3Q8IGY8 Leishmania donovani 79% 95%
A4HAF9 Leishmania braziliensis 57% 99%
A4I9L5 Leishmania infantum 79% 95%
Q4Q3G3 Leishmania major 77% 100%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS