LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania mexicana
UniProt:
E9B4G4_LEIMU
TriTrypDb:
LmxM.32.3250
Length:
386

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 5
NetGPI no yes: 0, no: 5
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B4G4
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B4G4

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 179 183 PF00656 0.558
CLV_C14_Caspase3-7 197 201 PF00656 0.477
CLV_NRD_NRD_1 10 12 PF00675 0.518
CLV_NRD_NRD_1 135 137 PF00675 0.519
CLV_NRD_NRD_1 220 222 PF00675 0.706
CLV_NRD_NRD_1 223 225 PF00675 0.665
CLV_NRD_NRD_1 270 272 PF00675 0.706
CLV_NRD_NRD_1 32 34 PF00675 0.625
CLV_NRD_NRD_1 321 323 PF00675 0.634
CLV_NRD_NRD_1 58 60 PF00675 0.482
CLV_NRD_NRD_1 83 85 PF00675 0.536
CLV_PCSK_KEX2_1 135 137 PF00082 0.512
CLV_PCSK_KEX2_1 150 152 PF00082 0.389
CLV_PCSK_KEX2_1 220 222 PF00082 0.565
CLV_PCSK_KEX2_1 269 271 PF00082 0.704
CLV_PCSK_KEX2_1 321 323 PF00082 0.634
CLV_PCSK_KEX2_1 71 73 PF00082 0.561
CLV_PCSK_KEX2_1 83 85 PF00082 0.431
CLV_PCSK_PC1ET2_1 150 152 PF00082 0.527
CLV_PCSK_PC1ET2_1 71 73 PF00082 0.537
CLV_PCSK_SKI1_1 12 16 PF00082 0.380
CLV_PCSK_SKI1_1 253 257 PF00082 0.639
CLV_PCSK_SKI1_1 273 277 PF00082 0.515
CLV_PCSK_SKI1_1 71 75 PF00082 0.551
CLV_PCSK_SKI1_1 94 98 PF00082 0.487
DEG_Nend_UBRbox_1 1 4 PF02207 0.474
DEG_SPOP_SBC_1 215 219 PF00917 0.720
DEG_SPOP_SBC_1 298 302 PF00917 0.529
DEG_SPOP_SBC_1 37 41 PF00917 0.415
DOC_CKS1_1 265 270 PF01111 0.692
DOC_USP7_MATH_1 214 218 PF00917 0.723
DOC_USP7_MATH_1 299 303 PF00917 0.718
DOC_USP7_MATH_1 315 319 PF00917 0.524
DOC_USP7_MATH_1 359 363 PF00917 0.689
DOC_USP7_MATH_1 365 369 PF00917 0.605
DOC_USP7_MATH_1 37 41 PF00917 0.534
DOC_USP7_MATH_1 45 49 PF00917 0.549
DOC_USP7_UBL2_3 102 106 PF12436 0.536
DOC_USP7_UBL2_3 108 112 PF12436 0.482
DOC_USP7_UBL2_3 60 64 PF12436 0.577
DOC_WW_Pin1_4 204 209 PF00397 0.680
DOC_WW_Pin1_4 264 269 PF00397 0.693
DOC_WW_Pin1_4 313 318 PF00397 0.696
DOC_WW_Pin1_4 355 360 PF00397 0.633
DOC_WW_Pin1_4 363 368 PF00397 0.590
LIG_14-3-3_CanoR_1 220 226 PF00244 0.700
LIG_14-3-3_CanoR_1 72 78 PF00244 0.562
LIG_eIF4E_1 308 314 PF01652 0.530
LIG_FHA_1 157 163 PF00498 0.487
LIG_FHA_1 169 175 PF00498 0.570
LIG_FHA_1 280 286 PF00498 0.579
LIG_FHA_1 299 305 PF00498 0.574
LIG_FHA_2 301 307 PF00498 0.565
LIG_PDZ_Class_2 381 386 PF00595 0.649
LIG_SH3_1 271 277 PF00018 0.547
LIG_SH3_2 265 270 PF14604 0.692
LIG_SH3_2 317 322 PF14604 0.592
LIG_SH3_3 255 261 PF00018 0.666
LIG_SH3_3 262 268 PF00018 0.651
LIG_SH3_3 271 277 PF00018 0.555
LIG_SH3_3 314 320 PF00018 0.623
LIG_SH3_3 51 57 PF00018 0.684
LIG_TRAF2_1 164 167 PF00917 0.558
LIG_TRAF2_1 229 232 PF00917 0.525
LIG_TRAF2_1 303 306 PF00917 0.702
LIG_TRAF2_1 309 312 PF00917 0.636
MOD_CDK_SPK_2 264 269 PF00069 0.693
MOD_CDK_SPxK_1 264 270 PF00069 0.694
MOD_CDK_SPxxK_3 264 271 PF00069 0.694
MOD_CK1_1 219 225 PF00069 0.710
MOD_CK2_1 120 126 PF00069 0.375
MOD_CK2_1 226 232 PF00069 0.645
MOD_CK2_1 300 306 PF00069 0.565
MOD_CK2_1 330 336 PF00069 0.608
MOD_CK2_1 37 43 PF00069 0.419
MOD_GlcNHglycan 162 165 PF01048 0.408
MOD_GlcNHglycan 228 231 PF01048 0.626
MOD_GlcNHglycan 238 243 PF01048 0.576
MOD_GlcNHglycan 286 289 PF01048 0.664
MOD_GlcNHglycan 332 335 PF01048 0.578
MOD_GlcNHglycan 367 370 PF01048 0.635
MOD_GSK3_1 156 163 PF00069 0.459
MOD_GSK3_1 215 222 PF00069 0.707
MOD_GSK3_1 234 241 PF00069 0.520
MOD_GSK3_1 351 358 PF00069 0.663
MOD_GSK3_1 359 366 PF00069 0.609
MOD_N-GLC_1 226 231 PF02516 0.667
MOD_NEK2_1 129 134 PF00069 0.462
MOD_NEK2_1 73 78 PF00069 0.559
MOD_NEK2_2 45 50 PF00069 0.467
MOD_PIKK_1 219 225 PF00454 0.670
MOD_PIKK_1 315 321 PF00454 0.658
MOD_PKA_2 219 225 PF00069 0.710
MOD_Plk_1 129 135 PF00069 0.499
MOD_Plk_4 359 365 PF00069 0.524
MOD_ProDKin_1 204 210 PF00069 0.677
MOD_ProDKin_1 264 270 PF00069 0.694
MOD_ProDKin_1 313 319 PF00069 0.698
MOD_ProDKin_1 355 361 PF00069 0.633
MOD_ProDKin_1 363 369 PF00069 0.590
MOD_SUMO_for_1 14 17 PF00179 0.379
MOD_SUMO_for_1 96 99 PF00179 0.518
MOD_SUMO_rev_2 249 258 PF00179 0.536
MOD_SUMO_rev_2 99 103 PF00179 0.457
TRG_DiLeu_BaEn_1 173 178 PF01217 0.536
TRG_ER_diArg_1 268 271 PF00400 0.698
TRG_ER_diArg_1 320 322 PF00400 0.637
TRG_ER_diArg_1 77 80 PF00400 0.401
TRG_NLS_Bipartite_1 71 88 PF00514 0.513
TRG_NLS_MonoExtN_4 83 88 PF00514 0.545
TRG_Pf-PMV_PEXEL_1 145 149 PF00026 0.490

Homologs

Protein Taxonomy Sequence identity Coverage
A0A3Q8IUB2 Leishmania donovani 78% 84%
A4HM33 Leishmania braziliensis 53% 98%
A4I9G6 Leishmania infantum 77% 84%
Q4Q3L1 Leishmania major 77% 98%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS