LeishMANIAdb
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H1 histone-like protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
H1 histone-like protein
Gene product:
h1 histone-like protein
Species:
Leishmania mexicana
UniProt:
E9B4G3_LEIMU
TriTrypDb:
LmxM.32.3240
Length:
142

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 5
NetGPI no yes: 0, no: 5
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B4G3
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B4G3

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 10 12 PF00675 0.595
CLV_PCSK_SKI1_1 113 117 PF00082 0.599
CLV_PCSK_SKI1_1 119 123 PF00082 0.687
CLV_PCSK_SKI1_1 133 137 PF00082 0.566
CLV_PCSK_SKI1_1 86 90 PF00082 0.633
CLV_PCSK_SKI1_1 95 99 PF00082 0.601
DEG_APCC_DBOX_1 2 10 PF00400 0.531
DEG_Nend_Nbox_1 1 3 PF02207 0.748
DOC_MAPK_gen_1 98 107 PF00069 0.602
DOC_PP2B_LxvP_1 64 67 PF13499 0.488
DOC_USP7_MATH_1 79 83 PF00917 0.626
DOC_USP7_MATH_1 88 92 PF00917 0.653
DOC_USP7_UBL2_3 12 16 PF12436 0.762
DOC_USP7_UBL2_3 125 129 PF12436 0.800
DOC_USP7_UBL2_3 98 102 PF12436 0.613
LIG_14-3-3_CanoR_1 3 7 PF00244 0.736
LIG_14-3-3_CanoR_1 54 64 PF00244 0.643
LIG_SH3_3 118 124 PF00018 0.588
LIG_SH3_3 39 45 PF00018 0.713
LIG_SH3_3 94 100 PF00018 0.702
MOD_CK1_1 19 25 PF00069 0.749
MOD_CK1_1 91 97 PF00069 0.783
MOD_Cter_Amidation 72 75 PF01082 0.813
MOD_GlcNHglycan 125 128 PF01048 0.614
MOD_GlcNHglycan 136 139 PF01048 0.612
MOD_GlcNHglycan 21 24 PF01048 0.699
MOD_GlcNHglycan 34 37 PF01048 0.496
MOD_NEK2_1 2 7 PF00069 0.696
MOD_NEK2_2 49 54 PF00069 0.724
MOD_PIKK_1 55 61 PF00454 0.742
MOD_PKA_2 19 25 PF00069 0.700
MOD_PKA_2 2 8 PF00069 0.735
MOD_PKA_2 91 97 PF00069 0.795
TRG_NLS_MonoExtN_4 92 99 PF00514 0.605

Homologs

Protein Taxonomy Sequence identity Coverage
A0A3Q8IH60 Leishmania donovani 75% 100%
A4HM32 Leishmania braziliensis 60% 100%
A4I9G5 Leishmania infantum 75% 100%
Q4Q3L2 Leishmania major 80% 100%

Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS