Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9B4F7_LEIMU

TriTrypDb:

LmxM.32.3180

Length:

804

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	yes	yes: 20

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	yes	yes: 1, no: 4
NetGPI	no	yes: 0, no: 5

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	5
GO:0110165	cellular anatomical entity	1	5

Expansion

Sequence features

E9B4F7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

No structure information available for this entry

Related structures:

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	728	732	PF00656	0.556
CLV_NRD_NRD_1	339	341	PF00675	0.629
CLV_NRD_NRD_1	550	552	PF00675	0.626
CLV_PCSK_KEX2_1	287	289	PF00082	0.557
CLV_PCSK_KEX2_1	338	340	PF00082	0.631
CLV_PCSK_KEX2_1	498	500	PF00082	0.416
CLV_PCSK_KEX2_1	549	551	PF00082	0.628
CLV_PCSK_PC1ET2_1	287	289	PF00082	0.557
CLV_PCSK_PC1ET2_1	498	500	PF00082	0.408
DEG_Kelch_Keap1_1	461	466	PF01344	0.573
DEG_Kelch_Keap1_1	672	677	PF01344	0.555
DEG_Kelch_Keap1_1	718	723	PF01344	0.568
DEG_SPOP_SBC_1	24	28	PF00917	0.419
DEG_SPOP_SBC_1	60	64	PF00917	0.332
DOC_MAPK_gen_1	272	281	PF00069	0.521
DOC_MAPK_MEF2A_6	206	213	PF00069	0.516
DOC_PP1_RVXF_1	321	328	PF00149	0.520
DOC_PP1_RVXF_1	532	539	PF00149	0.288
DOC_USP7_MATH_1	105	109	PF00917	0.441
DOC_USP7_MATH_1	199	203	PF00917	0.293
DOC_USP7_MATH_1	32	36	PF00917	0.442
DOC_USP7_MATH_1	437	441	PF00917	0.679
DOC_USP7_MATH_1	60	64	PF00917	0.512
DOC_USP7_MATH_1	648	652	PF00917	0.520
DOC_USP7_UBL2_3	226	230	PF12436	0.367
LIG_14-3-3_CanoR_1	130	139	PF00244	0.509
LIG_14-3-3_CanoR_1	158	166	PF00244	0.513
LIG_14-3-3_CanoR_1	288	298	PF00244	0.512
LIG_14-3-3_CanoR_1	499	509	PF00244	0.586
LIG_14-3-3_CanoR_1	86	94	PF00244	0.461
LIG_BIR_II_1	1	5	PF00653	0.290
LIG_BIR_III_2	398	402	PF00653	0.601
LIG_BIR_III_2	609	613	PF00653	0.403
LIG_BIR_III_4	357	361	PF00653	0.844
LIG_BIR_III_4	386	390	PF00653	0.568
LIG_BIR_III_4	568	572	PF00653	0.460
LIG_BIR_III_4	597	601	PF00653	0.369
LIG_EVH1_2	365	369	PF00568	0.852
LIG_EVH1_2	576	580	PF00568	0.453
LIG_FHA_1	107	113	PF00498	0.291
LIG_FHA_1	176	182	PF00498	0.440
LIG_FHA_1	28	34	PF00498	0.448
LIG_FHA_1	444	450	PF00498	0.605
LIG_FHA_1	53	59	PF00498	0.550
LIG_FHA_1	60	66	PF00498	0.452
LIG_FHA_1	655	661	PF00498	0.457
LIG_FHA_1	782	788	PF00498	0.656
LIG_FHA_1	89	95	PF00498	0.502
LIG_FHA_2	198	204	PF00498	0.448
LIG_FHA_2	713	719	PF00498	0.652
LIG_FHA_2	726	732	PF00498	0.454
LIG_FHA_2	754	760	PF00498	0.626
LIG_FHA_2	771	777	PF00498	0.480
LIG_LIR_Apic_2	150	156	PF02991	0.496
LIG_LIR_Apic_2	458	462	PF02991	0.582
LIG_LIR_Apic_2	669	673	PF02991	0.618
LIG_LIR_Apic_2	715	719	PF02991	0.592
LIG_LIR_Apic_2	751	755	PF02991	0.462
LIG_LIR_Gen_1	160	171	PF02991	0.457
LIG_LIR_Gen_1	218	228	PF02991	0.491
LIG_LIR_Nem_3	108	113	PF02991	0.501
LIG_LIR_Nem_3	160	166	PF02991	0.476
LIG_LIR_Nem_3	218	223	PF02991	0.493
LIG_LIR_Nem_3	303	309	PF02991	0.580
LIG_LIR_Nem_3	514	520	PF02991	0.477
LIG_LIR_Nem_3	711	716	PF02991	0.607
LIG_Pex14_1	307	311	PF04695	0.502
LIG_Pex14_1	518	522	PF04695	0.288
LIG_Pex14_2	322	326	PF04695	0.648
LIG_Pex14_2	533	537	PF04695	0.288
LIG_SH2_CRK	153	157	PF00017	0.527
LIG_SH2_CRK	163	167	PF00017	0.397
LIG_SH2_CRK	220	224	PF00017	0.445
LIG_SH2_CRK	352	356	PF00017	0.611
LIG_SH2_CRK	563	567	PF00017	0.422
LIG_SH2_GRB2like	352	355	PF00017	0.607
LIG_SH2_GRB2like	459	462	PF00017	0.579
LIG_SH2_GRB2like	563	566	PF00017	0.417
LIG_SH2_GRB2like	670	673	PF00017	0.563
LIG_SH2_GRB2like	741	744	PF00017	0.538
LIG_SH2_NCK_1	220	224	PF00017	0.417
LIG_SH2_NCK_1	352	356	PF00017	0.611
LIG_SH2_NCK_1	563	567	PF00017	0.422
LIG_SH2_NCK_1	727	731	PF00017	0.645
LIG_SH2_PTP2	413	416	PF00017	0.748
LIG_SH2_PTP2	459	462	PF00017	0.579
LIG_SH2_PTP2	624	627	PF00017	0.432
LIG_SH2_PTP2	670	673	PF00017	0.563
LIG_SH2_PTP2	716	719	PF00017	0.590
LIG_SH2_PTP2	752	755	PF00017	0.560
LIG_SH2_PTP2	788	791	PF00017	0.630
LIG_SH2_SRC	165	168	PF00017	0.518
LIG_SH2_SRC	459	462	PF00017	0.579
LIG_SH2_SRC	670	673	PF00017	0.618
LIG_SH2_SRC	716	719	PF00017	0.590
LIG_SH2_SRC	739	742	PF00017	0.601
LIG_SH2_SRC	750	753	PF00017	0.537
LIG_SH2_SRC	788	791	PF00017	0.630
LIG_SH2_STAP1	392	396	PF00017	0.778
LIG_SH2_STAP1	603	607	PF00017	0.385
LIG_SH2_STAP1	763	767	PF00017	0.686
LIG_SH2_STAT5	111	114	PF00017	0.450
LIG_SH2_STAT5	153	156	PF00017	0.437
LIG_SH2_STAT5	165	168	PF00017	0.468
LIG_SH2_STAT5	180	183	PF00017	0.324
LIG_SH2_STAT5	191	194	PF00017	0.376
LIG_SH2_STAT5	195	198	PF00017	0.378
LIG_SH2_STAT5	220	223	PF00017	0.501
LIG_SH2_STAT5	238	241	PF00017	0.493
LIG_SH2_STAT5	324	327	PF00017	0.645
LIG_SH2_STAT5	352	355	PF00017	0.607
LIG_SH2_STAT5	413	416	PF00017	0.786
LIG_SH2_STAT5	424	427	PF00017	0.745
LIG_SH2_STAT5	459	462	PF00017	0.579
LIG_SH2_STAT5	470	473	PF00017	0.613
LIG_SH2_STAT5	535	538	PF00017	0.328
LIG_SH2_STAT5	563	566	PF00017	0.417
LIG_SH2_STAT5	624	627	PF00017	0.432
LIG_SH2_STAT5	635	638	PF00017	0.427
LIG_SH2_STAT5	670	673	PF00017	0.579
LIG_SH2_STAT5	681	684	PF00017	0.536
LIG_SH2_STAT5	716	719	PF00017	0.576
LIG_SH2_STAT5	727	730	PF00017	0.492
LIG_SH2_STAT5	752	755	PF00017	0.616
LIG_SH2_STAT5	763	766	PF00017	0.557
LIG_SH2_STAT5	788	791	PF00017	0.630
LIG_SH2_STAT5	83	86	PF00017	0.294
LIG_SH3_3	208	214	PF00018	0.520
LIG_SH3_3	482	488	PF00018	0.629
LIG_SUMO_SIM_par_1	221	227	PF11976	0.332
LIG_TRAF2_1	477	480	PF00917	0.605
LIG_TRAF2_1	688	691	PF00917	0.531
LIG_TRFH_1	180	184	PF08558	0.505
MOD_CK1_1	142	148	PF00069	0.383
MOD_CK1_1	215	221	PF00069	0.414
MOD_CK1_1	27	33	PF00069	0.454
MOD_CK1_1	291	297	PF00069	0.453
MOD_CK1_1	440	446	PF00069	0.621
MOD_CK1_1	502	508	PF00069	0.584
MOD_CK1_1	59	65	PF00069	0.507
MOD_CK1_1	651	657	PF00069	0.574
MOD_CK1_1	88	94	PF00069	0.429
MOD_CK1_1	97	103	PF00069	0.402
MOD_CK2_1	197	203	PF00069	0.447
MOD_CK2_1	264	270	PF00069	0.367
MOD_CK2_1	279	285	PF00069	0.522
MOD_CK2_1	717	723	PF00069	0.503
MOD_CK2_1	753	759	PF00069	0.620
MOD_CK2_1	770	776	PF00069	0.479
MOD_GlcNHglycan	120	123	PF01048	0.583
MOD_GlcNHglycan	132	135	PF01048	0.692
MOD_GlcNHglycan	192	195	PF01048	0.625
MOD_GlcNHglycan	266	269	PF01048	0.515
MOD_GlcNHglycan	362	365	PF01048	0.594
MOD_GlcNHglycan	4	7	PF01048	0.604
MOD_GlcNHglycan	42	45	PF01048	0.622
MOD_GlcNHglycan	430	433	PF01048	0.500
MOD_GlcNHglycan	573	576	PF01048	0.704
MOD_GlcNHglycan	58	61	PF01048	0.747
MOD_GlcNHglycan	641	644	PF01048	0.691
MOD_GlcNHglycan	70	73	PF01048	0.576
MOD_GlcNHglycan	74	77	PF01048	0.530
MOD_GSK3_1	120	127	PF00069	0.493
MOD_GSK3_1	138	145	PF00069	0.275
MOD_GSK3_1	147	154	PF00069	0.361
MOD_GSK3_1	157	164	PF00069	0.392
MOD_GSK3_1	197	204	PF00069	0.419
MOD_GSK3_1	20	27	PF00069	0.558
MOD_GSK3_1	28	35	PF00069	0.424
MOD_GSK3_1	290	297	PF00069	0.465
MOD_GSK3_1	439	446	PF00069	0.623
MOD_GSK3_1	46	53	PF00069	0.449
MOD_GSK3_1	464	471	PF00069	0.596
MOD_GSK3_1	501	508	PF00069	0.587
MOD_GSK3_1	56	63	PF00069	0.544
MOD_GSK3_1	64	71	PF00069	0.374
MOD_GSK3_1	650	657	PF00069	0.590
MOD_GSK3_1	675	682	PF00069	0.567
MOD_GSK3_1	717	724	PF00069	0.584
MOD_GSK3_1	753	760	PF00069	0.569
MOD_GSK3_1	94	101	PF00069	0.395
MOD_N-GLC_1	106	111	PF02516	0.701
MOD_N-GLC_1	38	43	PF02516	0.655
MOD_N-GLC_1	447	452	PF02516	0.399
MOD_N-GLC_1	65	70	PF02516	0.613
MOD_N-GLC_1	658	663	PF02516	0.667
MOD_N-GLC_1	770	775	PF02516	0.816
MOD_NEK2_1	139	144	PF00069	0.461
MOD_NEK2_1	146	151	PF00069	0.401
MOD_NEK2_1	264	269	PF00069	0.317
MOD_NEK2_1	289	294	PF00069	0.373
MOD_NEK2_1	369	374	PF00069	0.726
MOD_NEK2_1	38	43	PF00069	0.416
MOD_NEK2_1	455	460	PF00069	0.592
MOD_NEK2_1	500	505	PF00069	0.602
MOD_NEK2_1	580	585	PF00069	0.440
MOD_NEK2_1	666	671	PF00069	0.422
MOD_NEK2_1	94	99	PF00069	0.514
MOD_NEK2_2	201	206	PF00069	0.459
MOD_PIKK_1	111	117	PF00454	0.503
MOD_PIKK_1	437	443	PF00454	0.628
MOD_PIKK_1	648	654	PF00454	0.565
MOD_PIKK_1	725	731	PF00454	0.547
MOD_PKA_2	129	135	PF00069	0.510
MOD_PKA_2	157	163	PF00069	0.513
MOD_PKA_2	205	211	PF00069	0.477
MOD_PKA_2	294	300	PF00069	0.484
MOD_PKA_2	505	511	PF00069	0.550
MOD_PKA_2	85	91	PF00069	0.497
MOD_PKB_1	328	336	PF00069	0.705
MOD_PKB_1	539	547	PF00069	0.367
MOD_Plk_1	106	112	PF00069	0.339
MOD_Plk_1	20	26	PF00069	0.460
MOD_Plk_1	215	221	PF00069	0.289
MOD_Plk_1	369	375	PF00069	0.782
MOD_Plk_1	38	44	PF00069	0.330
MOD_Plk_1	580	586	PF00069	0.436
MOD_Plk_1	65	71	PF00069	0.412
MOD_Plk_1	88	94	PF00069	0.434
MOD_Plk_4	106	112	PF00069	0.360
MOD_Plk_4	120	126	PF00069	0.378
MOD_Plk_4	161	167	PF00069	0.508
MOD_Plk_4	205	211	PF00069	0.496
MOD_Plk_4	215	221	PF00069	0.399
MOD_Plk_4	455	461	PF00069	0.590
MOD_Plk_4	666	672	PF00069	0.574
MOD_Plk_4	712	718	PF00069	0.595
MOD_Plk_4	94	100	PF00069	0.514
MOD_SUMO_rev_2	282	289	PF00179	0.348
MOD_SUMO_rev_2	495	500	PF00179	0.607
TRG_ENDOCYTIC_2	110	113	PF00928	0.505
TRG_ENDOCYTIC_2	163	166	PF00928	0.514
TRG_ENDOCYTIC_2	220	223	PF00928	0.501
TRG_ENDOCYTIC_2	273	276	PF00928	0.458
TRG_ENDOCYTIC_2	306	309	PF00928	0.580
TRG_ENDOCYTIC_2	324	327	PF00928	0.488
TRG_ENDOCYTIC_2	517	520	PF00928	0.288
TRG_ENDOCYTIC_2	535	538	PF00928	0.293
TRG_ENDOCYTIC_2	750	753	PF00928	0.506
TRG_ENDOCYTIC_2	799	802	PF00928	0.431
TRG_ER_diArg_1	327	330	PF00400	0.625
TRG_ER_diArg_1	338	340	PF00400	0.607
TRG_ER_diArg_1	538	541	PF00400	0.331
TRG_ER_diArg_1	549	551	PF00400	0.413

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3S7X786	Leishmania donovani	84%	100%
A4HM25	Leishmania braziliensis	64%	100%
A4I9F9	Leishmania infantum	84%	100%
Q4Q3L8	Leishmania major	83%	100%