Transmembrane protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Download

Quick info

Protein:

Gene product:

Proteophosphoglycan PPG2

Species:

Leishmania mexicana

UniProt:

E9B4C4_LEIMU

TriTrypDb:

LmxM.32.2835

Length:

622

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 1
NetGPI	no	yes: 0, no: 1

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	2
GO:0110165	cellular anatomical entity	1	2

Expansion

Sequence features

E9B4C4

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B4C4

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	512	516	PF00656	0.615
CLV_NRD_NRD_1	412	414	PF00675	0.355
CLV_NRD_NRD_1	469	471	PF00675	0.399
CLV_NRD_NRD_1	508	510	PF00675	0.416
CLV_NRD_NRD_1	557	559	PF00675	0.413
CLV_NRD_NRD_1	7	9	PF00675	0.418
CLV_PCSK_KEX2_1	382	384	PF00082	0.631
CLV_PCSK_KEX2_1	412	414	PF00082	0.355
CLV_PCSK_KEX2_1	508	510	PF00082	0.416
CLV_PCSK_KEX2_1	7	9	PF00082	0.418
CLV_PCSK_PC1ET2_1	382	384	PF00082	0.631
CLV_PCSK_SKI1_1	383	387	PF00082	0.608
DEG_APCC_KENBOX_2	495	499	PF00400	0.608
DEG_SCF_FBW7_1	565	572	PF00400	0.606
DOC_MAPK_gen_1	13	21	PF00069	0.400
DOC_MAPK_MEF2A_6	15	23	PF00069	0.400
DOC_USP7_MATH_1	113	117	PF00917	0.392
DOC_USP7_MATH_1	122	126	PF00917	0.350
DOC_USP7_MATH_1	146	150	PF00917	0.347
DOC_USP7_MATH_1	170	174	PF00917	0.341
DOC_USP7_MATH_1	194	198	PF00917	0.337
DOC_USP7_MATH_1	2	6	PF00917	0.628
DOC_USP7_MATH_1	218	222	PF00917	0.334
DOC_USP7_MATH_1	242	246	PF00917	0.333
DOC_USP7_MATH_1	266	270	PF00917	0.337
DOC_USP7_MATH_1	290	294	PF00917	0.341
DOC_USP7_MATH_1	314	318	PF00917	0.340
DOC_USP7_MATH_1	338	342	PF00917	0.348
DOC_USP7_MATH_1	507	511	PF00917	0.613
DOC_USP7_MATH_1	513	517	PF00917	0.618
DOC_USP7_MATH_1	547	551	PF00917	0.617
DOC_USP7_MATH_1	569	573	PF00917	0.610
DOC_USP7_MATH_1	57	61	PF00917	0.413
DOC_USP7_MATH_2	113	119	PF00917	0.388
DOC_USP7_UBL2_3	382	386	PF12436	0.419
DOC_USP7_UBL2_3	496	500	PF12436	0.606
DOC_USP7_UBL2_3	551	555	PF12436	0.615
DOC_WW_Pin1_4	375	380	PF00397	0.430
DOC_WW_Pin1_4	565	570	PF00397	0.604
LIG_14-3-3_CanoR_1	13	19	PF00244	0.400
LIG_14-3-3_CanoR_1	412	421	PF00244	0.582
LIG_14-3-3_CanoR_1	431	436	PF00244	0.599
LIG_14-3-3_CanoR_1	442	447	PF00244	0.598
LIG_14-3-3_CanoR_1	587	591	PF00244	0.630
LIG_APCC_ABBAyCdc20_2	73	79	PF00400	0.410
LIG_BIR_II_1	1	5	PF00653	0.630
LIG_BIR_III_1	1	5	PF00653	0.630
LIG_BIR_III_3	1	5	PF00653	0.630
LIG_BRCT_BRCA1_1	117	121	PF00533	0.366
LIG_BRCT_BRCA1_1	132	136	PF00533	0.347
LIG_BRCT_BRCA1_1	141	145	PF00533	0.336
LIG_BRCT_BRCA1_1	156	160	PF00533	0.340
LIG_BRCT_BRCA1_1	165	169	PF00533	0.329
LIG_BRCT_BRCA1_1	180	184	PF00533	0.339
LIG_BRCT_BRCA1_1	189	193	PF00533	0.324
LIG_BRCT_BRCA1_1	204	208	PF00533	0.335
LIG_BRCT_BRCA1_1	213	217	PF00533	0.319
LIG_BRCT_BRCA1_1	228	232	PF00533	0.332
LIG_BRCT_BRCA1_1	237	241	PF00533	0.318
LIG_BRCT_BRCA1_1	252	256	PF00533	0.334
LIG_BRCT_BRCA1_1	261	265	PF00533	0.321
LIG_BRCT_BRCA1_1	276	280	PF00533	0.339
LIG_BRCT_BRCA1_1	285	289	PF00533	0.326
LIG_BRCT_BRCA1_1	300	304	PF00533	0.341
LIG_BRCT_BRCA1_1	309	313	PF00533	0.325
LIG_BRCT_BRCA1_1	324	328	PF00533	0.345
LIG_BRCT_BRCA1_1	333	337	PF00533	0.333
LIG_deltaCOP1_diTrp_1	617	622	PF00928	0.620
LIG_EH1_1	401	409	PF00400	0.199
LIG_FHA_1	366	372	PF00498	0.400
LIG_FHA_1	390	396	PF00498	0.199
LIG_FHA_2	525	531	PF00498	0.610
LIG_LIR_Gen_1	31	39	PF02991	0.199
LIG_LIR_Gen_1	430	441	PF02991	0.598
LIG_LIR_Gen_1	486	495	PF02991	0.614
LIG_LIR_Gen_1	515	521	PF02991	0.619
LIG_LIR_Nem_3	31	36	PF02991	0.199
LIG_LIR_Nem_3	430	436	PF02991	0.600
LIG_LIR_Nem_3	486	491	PF02991	0.613
LIG_LIR_Nem_3	515	520	PF02991	0.621
LIG_Pex14_2	23	27	PF04695	0.199
LIG_Pex14_2	398	402	PF04695	0.199
LIG_SH2_CRK	33	37	PF00017	0.199
LIG_SH2_CRK	443	447	PF00017	0.598
LIG_SH2_NCK_1	488	492	PF00017	0.616
LIG_SH2_STAT5	33	36	PF00017	0.199
LIG_SH2_STAT5	453	456	PF00017	0.604
LIG_SH3_3	541	547	PF00018	0.617
LIG_TYR_ITIM	441	446	PF00017	0.595
LIG_Vh1_VBS_1	21	39	PF01044	0.199
MOD_CDK_SPxxK_3	375	382	PF00069	0.430
MOD_CK1_1	116	122	PF00069	0.371
MOD_CK1_1	125	131	PF00069	0.352
MOD_CK1_1	135	141	PF00069	0.353
MOD_CK1_1	149	155	PF00069	0.350
MOD_CK1_1	159	165	PF00069	0.335
MOD_CK1_1	173	179	PF00069	0.344
MOD_CK1_1	183	189	PF00069	0.329
MOD_CK1_1	197	203	PF00069	0.339
MOD_CK1_1	207	213	PF00069	0.323
MOD_CK1_1	221	227	PF00069	0.337
MOD_CK1_1	231	237	PF00069	0.320
MOD_CK1_1	245	251	PF00069	0.337
MOD_CK1_1	255	261	PF00069	0.323
MOD_CK1_1	269	275	PF00069	0.342
MOD_CK1_1	279	285	PF00069	0.328
MOD_CK1_1	293	299	PF00069	0.345
MOD_CK1_1	303	309	PF00069	0.328
MOD_CK1_1	317	323	PF00069	0.344
MOD_CK1_1	327	333	PF00069	0.343
MOD_CK1_1	340	346	PF00069	0.369
MOD_CK1_1	347	353	PF00069	0.404
MOD_CK1_1	375	381	PF00069	0.429
MOD_CK1_1	489	495	PF00069	0.616
MOD_CK1_1	534	540	PF00069	0.615
MOD_CK1_1	550	556	PF00069	0.613
MOD_CK1_1	572	578	PF00069	0.626
MOD_CK1_1	60	66	PF00069	0.411
MOD_CK1_1	99	105	PF00069	0.383
MOD_CK2_1	125	131	PF00069	0.352
MOD_CK2_1	149	155	PF00069	0.350
MOD_CK2_1	173	179	PF00069	0.344
MOD_CK2_1	197	203	PF00069	0.339
MOD_CK2_1	221	227	PF00069	0.337
MOD_CK2_1	245	251	PF00069	0.337
MOD_CK2_1	269	275	PF00069	0.342
MOD_CK2_1	293	299	PF00069	0.345
MOD_CK2_1	317	323	PF00069	0.344
MOD_CK2_1	345	351	PF00069	0.400
MOD_CK2_1	524	530	PF00069	0.610
MOD_CK2_1	574	580	PF00069	0.626
MOD_Cter_Amidation	410	413	PF01082	0.399
MOD_Cter_Amidation	468	471	PF01082	0.400
MOD_GlcNHglycan	115	118	PF01048	0.587
MOD_GlcNHglycan	126	130	PF01048	0.552
MOD_GlcNHglycan	137	140	PF01048	0.563
MOD_GlcNHglycan	150	154	PF01048	0.549
MOD_GlcNHglycan	161	164	PF01048	0.539
MOD_GlcNHglycan	174	178	PF01048	0.543
MOD_GlcNHglycan	185	188	PF01048	0.530
MOD_GlcNHglycan	198	202	PF01048	0.538
MOD_GlcNHglycan	209	212	PF01048	0.525
MOD_GlcNHglycan	222	226	PF01048	0.536
MOD_GlcNHglycan	233	236	PF01048	0.520
MOD_GlcNHglycan	246	250	PF01048	0.536
MOD_GlcNHglycan	257	260	PF01048	0.524
MOD_GlcNHglycan	270	274	PF01048	0.541
MOD_GlcNHglycan	281	284	PF01048	0.530
MOD_GlcNHglycan	294	298	PF01048	0.543
MOD_GlcNHglycan	305	308	PF01048	0.532
MOD_GlcNHglycan	318	322	PF01048	0.542
MOD_GlcNHglycan	329	332	PF01048	0.552
MOD_GlcNHglycan	415	418	PF01048	0.389
MOD_GlcNHglycan	427	430	PF01048	0.404
MOD_GlcNHglycan	50	53	PF01048	0.592
MOD_GlcNHglycan	509	512	PF01048	0.410
MOD_GlcNHglycan	524	527	PF01048	0.406
MOD_GlcNHglycan	534	537	PF01048	0.416
MOD_GlcNHglycan	574	577	PF01048	0.430
MOD_GlcNHglycan	580	584	PF01048	0.413
MOD_GlcNHglycan	598	601	PF01048	0.426
MOD_GlcNHglycan	98	101	PF01048	0.594
MOD_GSK3_1	113	120	PF00069	0.386
MOD_GSK3_1	121	128	PF00069	0.349
MOD_GSK3_1	131	138	PF00069	0.354
MOD_GSK3_1	141	148	PF00069	0.339
MOD_GSK3_1	155	162	PF00069	0.342
MOD_GSK3_1	165	172	PF00069	0.333
MOD_GSK3_1	179	186	PF00069	0.338
MOD_GSK3_1	189	196	PF00069	0.328
MOD_GSK3_1	203	210	PF00069	0.334
MOD_GSK3_1	213	220	PF00069	0.324
MOD_GSK3_1	227	234	PF00069	0.331
MOD_GSK3_1	237	244	PF00069	0.322
MOD_GSK3_1	251	258	PF00069	0.333
MOD_GSK3_1	261	268	PF00069	0.326
MOD_GSK3_1	275	282	PF00069	0.339
MOD_GSK3_1	285	292	PF00069	0.331
MOD_GSK3_1	299	306	PF00069	0.340
MOD_GSK3_1	309	316	PF00069	0.330
MOD_GSK3_1	323	330	PF00069	0.346
MOD_GSK3_1	333	340	PF00069	0.336
MOD_GSK3_1	341	348	PF00069	0.379
MOD_GSK3_1	363	370	PF00069	0.400
MOD_GSK3_1	373	380	PF00069	0.429
MOD_GSK3_1	427	434	PF00069	0.603
MOD_GSK3_1	441	448	PF00069	0.597
MOD_GSK3_1	531	538	PF00069	0.614
MOD_GSK3_1	545	552	PF00069	0.618
MOD_GSK3_1	565	572	PF00069	0.606
MOD_GSK3_1	575	582	PF00069	0.622
MOD_GSK3_1	586	593	PF00069	0.628
MOD_GSK3_1	60	67	PF00069	0.411
MOD_GSK3_1	92	99	PF00069	0.390
MOD_N-GLC_1	522	527	PF02516	0.409
MOD_NEK2_1	32	37	PF00069	0.199
MOD_NEK2_1	337	342	PF00069	0.344
MOD_NEK2_1	365	370	PF00069	0.397
MOD_NEK2_1	441	446	PF00069	0.595
MOD_NEK2_1	475	480	PF00069	0.614
MOD_NEK2_1	531	536	PF00069	0.614
MOD_NEK2_1	574	579	PF00069	0.626
MOD_NEK2_1	590	595	PF00069	0.626
MOD_NEK2_2	132	137	PF00069	0.352
MOD_NEK2_2	156	161	PF00069	0.342
MOD_NEK2_2	180	185	PF00069	0.339
MOD_NEK2_2	204	209	PF00069	0.335
MOD_NEK2_2	228	233	PF00069	0.332
MOD_NEK2_2	252	257	PF00069	0.335
MOD_NEK2_2	276	281	PF00069	0.339
MOD_NEK2_2	300	305	PF00069	0.340
MOD_NEK2_2	324	329	PF00069	0.345
MOD_NEK2_2	569	574	PF00069	0.614
MOD_PIKK_1	475	481	PF00454	0.613
MOD_PIKK_1	545	551	PF00454	0.618
MOD_PIKK_1	609	615	PF00454	0.625
MOD_PKA_1	7	13	PF00069	0.597
MOD_PKA_2	14	20	PF00069	0.400
MOD_PKA_2	441	447	PF00069	0.596
MOD_PKA_2	507	513	PF00069	0.613
MOD_PKA_2	586	592	PF00069	0.629
MOD_PKA_2	7	13	PF00069	0.597
MOD_PKB_1	440	448	PF00069	0.597
MOD_Plk_1	125	131	PF00069	0.352
MOD_Plk_1	149	155	PF00069	0.350
MOD_Plk_1	173	179	PF00069	0.344
MOD_Plk_1	197	203	PF00069	0.339
MOD_Plk_1	221	227	PF00069	0.337
MOD_Plk_1	245	251	PF00069	0.337
MOD_Plk_1	269	275	PF00069	0.342
MOD_Plk_1	293	299	PF00069	0.345
MOD_Plk_1	317	323	PF00069	0.344
MOD_Plk_1	363	369	PF00069	0.399
MOD_Plk_1	489	495	PF00069	0.616
MOD_Plk_4	14	20	PF00069	0.400
MOD_Plk_4	32	38	PF00069	0.199
MOD_Plk_4	431	437	PF00069	0.600
MOD_Plk_4	569	575	PF00069	0.616
MOD_Plk_4	586	592	PF00069	0.629
MOD_ProDKin_1	375	381	PF00069	0.429
MOD_ProDKin_1	565	571	PF00069	0.605
TRG_ENDOCYTIC_2	33	36	PF00928	0.199
TRG_ENDOCYTIC_2	433	436	PF00928	0.599
TRG_ENDOCYTIC_2	443	446	PF00928	0.597
TRG_ENDOCYTIC_2	453	456	PF00928	0.604
TRG_ENDOCYTIC_2	488	491	PF00928	0.616
TRG_ER_diArg_1	412	415	PF00400	0.561
TRG_ER_diArg_1	440	443	PF00400	0.595
TRG_NLS_MonoExtN_4	555	562	PF00514	0.615
TRG_Pf-PMV_PEXEL_1	44	48	PF00026	0.578