Putative Unc104-like kinesin

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

Unc104-like kinesin, putative

Species:

Leishmania mexicana

UniProt:

E9B495_LEIMU

TriTrypDb:

LmxM.32.2560

Length:

2075

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

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Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	1
GO:0005871	kinesin complex	3	1
GO:0005874	microtubule	6	1
GO:0005875	microtubule associated complex	2	1
GO:0032991	protein-containing complex	1	1
GO:0099080	supramolecular complex	2	1
GO:0099081	supramolecular polymer	3	1
GO:0099512	supramolecular fiber	4	1
GO:0099513	polymeric cytoskeletal fiber	5	1
GO:0110165	cellular anatomical entity	1	1

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Expansion

Sequence features

E9B495

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

No structure information available for this entry

Related structures:

Function

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Biological processes
Term	Name	Level	Count
GO:0006810	transport	3	1
GO:0007017	microtubule-based process	2	7
GO:0007018	microtubule-based movement	3	7
GO:0009987	cellular process	1	7
GO:0030705	cytoskeleton-dependent intracellular transport	4	1
GO:0046907	intracellular transport	3	1
GO:0051179	localization	1	1
GO:0051234	establishment of localization	2	1
GO:0051641	cellular localization	2	1
GO:0051649	establishment of localization in cell	3	1

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Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	7
GO:0003774	cytoskeletal motor activity	1	7
GO:0003777	microtubule motor activity	2	7
GO:0003824	catalytic activity	1	1
GO:0005488	binding	1	7
GO:0005515	protein binding	2	7
GO:0005524	ATP binding	5	7
GO:0008017	microtubule binding	5	7
GO:0008092	cytoskeletal protein binding	3	7
GO:0015631	tubulin binding	4	7

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Putative motif mimicry

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Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	1199	1203	PF00656	0.422
CLV_C14_Caspase3-7	1957	1961	PF00656	0.376
CLV_C14_Caspase3-7	248	252	PF00656	0.322
CLV_C14_Caspase3-7	368	372	PF00656	0.325
CLV_C14_Caspase3-7	554	558	PF00656	0.516
CLV_C14_Caspase3-7	741	745	PF00656	0.607
CLV_C14_Caspase3-7	763	767	PF00656	0.598
CLV_MEL_PAP_1	1813	1819	PF00089	0.293
CLV_NRD_NRD_1	1097	1099	PF00675	0.599
CLV_NRD_NRD_1	1255	1257	PF00675	0.397

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IMH6	Leptomonas seymouri	51%	96%
A0A3Q8II06	Leishmania donovani	85%	100%
A4HLW6	Leishmania braziliensis	68%	100%
A4I995	Leishmania infantum	85%	100%
Q4Q3T1	Leishmania major	83%	100%

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