LeishMANIAdb
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Protein-tyrosine-phosphatase

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Protein-tyrosine-phosphatase
Gene product:
hypothetical protein, conserved
Species:
Leishmania mexicana
UniProt:
E9B431_LEIMU
TriTrypDb:
LmxM.32.1940
Length:
1009

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 3
NetGPI no yes: 0, no: 3
Cellular components
TermNameLevelCount
GO:0016020 membrane 2 4
GO:0110165 cellular anatomical entity 1 4
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Expansion

Sequence features

E9B431
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B431

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 264 268 PF00656 0.481
CLV_C14_Caspase3-7 269 273 PF00656 0.594
CLV_C14_Caspase3-7 72 76 PF00656 0.520
CLV_C14_Caspase3-7 812 816 PF00656 0.540
CLV_NRD_NRD_1 138 140 PF00675 0.643
CLV_NRD_NRD_1 210 212 PF00675 0.652
CLV_NRD_NRD_1 348 350 PF00675 0.832
CLV_NRD_NRD_1 371 373 PF00675 0.682
CLV_NRD_NRD_1 388 390 PF00675 0.782
CLV_NRD_NRD_1 697 699 PF00675 0.703
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N0P838 Leptomonas seymouri 50% 97%
E9B2Z2 Leishmania mexicana (strain MHOM/GT/2001/U1103) 21% 100%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS