Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9B403_LEIMU

TriTrypDb:

LmxM.32.1660

Length:

204

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 8
NetGPI	no	yes: 0, no: 8

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B403

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B403

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	169	173	PF00656	0.517
CLV_C14_Caspase3-7	190	194	PF00656	0.525
CLV_C14_Caspase3-7	46	50	PF00656	0.500
CLV_NRD_NRD_1	137	139	PF00675	0.565
CLV_NRD_NRD_1	186	188	PF00675	0.479
CLV_NRD_NRD_1	99	101	PF00675	0.518
CLV_PCSK_KEX2_1	137	139	PF00082	0.565
CLV_PCSK_KEX2_1	186	188	PF00082	0.495
CLV_PCSK_KEX2_1	99	101	PF00082	0.593
CLV_PCSK_SKI1_1	160	164	PF00082	0.464
DEG_Nend_UBRbox_3	1	3	PF02207	0.705
DOC_PP4_FxxP_1	58	61	PF00568	0.582
DOC_USP7_MATH_1	109	113	PF00917	0.567
DOC_USP7_MATH_1	144	148	PF00917	0.615
DOC_USP7_MATH_1	173	177	PF00917	0.510
DOC_USP7_MATH_1	98	102	PF00917	0.479
DOC_WW_Pin1_4	105	110	PF00397	0.525
LIG_14-3-3_CanoR_1	186	192	PF00244	0.474
LIG_14-3-3_CanoR_1	99	103	PF00244	0.416
LIG_APCC_ABBA_1	149	154	PF00400	0.594
LIG_DLG_GKlike_1	187	195	PF00625	0.522
LIG_FHA_1	106	112	PF00498	0.643
LIG_FHA_1	11	17	PF00498	0.467
LIG_FHA_1	19	25	PF00498	0.383
LIG_FHA_2	29	35	PF00498	0.297
LIG_LIR_Gen_1	121	132	PF02991	0.482
LIG_LIR_Gen_1	161	170	PF02991	0.497
LIG_LIR_Gen_1	31	41	PF02991	0.558
LIG_LIR_Gen_1	49	58	PF02991	0.322
LIG_LIR_Nem_3	121	127	PF02991	0.526
LIG_LIR_Nem_3	161	165	PF02991	0.563
LIG_LIR_Nem_3	31	36	PF02991	0.440
LIG_LIR_Nem_3	49	55	PF02991	0.376
LIG_SH2_CRK	52	56	PF00017	0.466
LIG_SH2_CRK	68	72	PF00017	0.548
LIG_SH2_NCK_1	191	195	PF00017	0.534
LIG_SH2_SRC	191	194	PF00017	0.528
LIG_SH2_STAP1	52	56	PF00017	0.446
LIG_SH2_STAT5	102	105	PF00017	0.447
LIG_SH2_STAT5	107	110	PF00017	0.471
LIG_SH2_STAT5	124	127	PF00017	0.399
LIG_SH3_3	129	135	PF00018	0.516
LIG_TYR_ITIM	66	71	PF00017	0.418
MOD_CK2_1	144	150	PF00069	0.613
MOD_CK2_1	28	34	PF00069	0.295
MOD_GlcNHglycan	146	149	PF01048	0.609
MOD_GSK3_1	105	112	PF00069	0.573
MOD_GSK3_1	56	63	PF00069	0.517
MOD_NEK2_1	10	15	PF00069	0.517
MOD_NEK2_1	118	123	PF00069	0.470
MOD_NEK2_1	143	148	PF00069	0.557
MOD_NEK2_1	185	190	PF00069	0.545
MOD_NEK2_1	36	41	PF00069	0.530
MOD_PIKK_1	138	144	PF00454	0.477
MOD_PKA_2	185	191	PF00069	0.550
MOD_PKA_2	98	104	PF00069	0.418
MOD_Plk_1	138	144	PF00069	0.545
MOD_Plk_1	195	201	PF00069	0.526
MOD_Plk_4	51	57	PF00069	0.323
MOD_ProDKin_1	105	111	PF00069	0.536
TRG_ENDOCYTIC_2	124	127	PF00928	0.468
TRG_ENDOCYTIC_2	52	55	PF00928	0.385
TRG_ENDOCYTIC_2	68	71	PF00928	0.410
TRG_ER_diArg_1	185	187	PF00400	0.475
TRG_Pf-PMV_PEXEL_1	138	142	PF00026	0.527
TRG_Pf-PMV_PEXEL_1	4	9	PF00026	0.650

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PEU1	Leptomonas seymouri	54%	99%
A0A3R7KFM1	Trypanosoma rangeli	26%	94%
A0A3S7X6V4	Leishmania donovani	93%	100%
A4HLM7	Leishmania braziliensis	84%	100%
A4I938	Leishmania infantum	93%	100%
C9ZIV5	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	26%	100%
Q4Q421	Leishmania major	91%	100%