Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9B3Z5_LEIMU

TriTrypDb:

LmxM.32.1580

Length:

326

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 4
NetGPI	no	yes: 0, no: 4

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B3Z5

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B3Z5

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_MEL_PAP_1	221	227	PF00089	0.755
CLV_NRD_NRD_1	29	31	PF00675	0.650
CLV_PCSK_KEX2_1	274	276	PF00082	0.820
CLV_PCSK_KEX2_1	29	31	PF00082	0.650
CLV_PCSK_PC1ET2_1	274	276	PF00082	0.820
CLV_PCSK_SKI1_1	219	223	PF00082	0.680
CLV_PCSK_SKI1_1	22	26	PF00082	0.635
CLV_PCSK_SKI1_1	34	38	PF00082	0.427
CLV_PCSK_SKI1_1	40	44	PF00082	0.700
DEG_APCC_DBOX_1	124	132	PF00400	0.729
DEG_Nend_Nbox_1	1	3	PF02207	0.669
DEG_SCF_FBW7_1	4	11	PF00400	0.709
DEG_SPOP_SBC_1	309	313	PF00917	0.717
DOC_CKS1_1	60	65	PF01111	0.563
DOC_CYCLIN_RxL_1	104	115	PF00134	0.644
DOC_CYCLIN_RxL_1	19	28	PF00134	0.656
DOC_MAPK_gen_1	29	35	PF00069	0.618
DOC_PP1_RVXF_1	105	112	PF00149	0.637
DOC_PP1_RVXF_1	32	39	PF00149	0.618
DOC_PP2B_LxvP_1	323	326	PF13499	0.769
DOC_USP7_MATH_1	172	176	PF00917	0.703
DOC_WW_Pin1_4	302	307	PF00397	0.538
DOC_WW_Pin1_4	4	9	PF00397	0.700
DOC_WW_Pin1_4	59	64	PF00397	0.817
LIG_14-3-3_CanoR_1	120	124	PF00244	0.699
LIG_14-3-3_CanoR_1	150	154	PF00244	0.540
LIG_14-3-3_CanoR_1	184	192	PF00244	0.540
LIG_14-3-3_CanoR_1	34	39	PF00244	0.519
LIG_Actin_WH2_2	71	87	PF00022	0.651
LIG_DCNL_PONY_1	1	4	PF03556	0.681
LIG_FHA_1	116	122	PF00498	0.507
LIG_FHA_1	132	138	PF00498	0.540
LIG_FHA_1	184	190	PF00498	0.711
LIG_FHA_1	199	205	PF00498	0.404
LIG_FHA_1	254	260	PF00498	0.666
LIG_FHA_1	280	286	PF00498	0.776
LIG_FHA_1	5	11	PF00498	0.664
LIG_FHA_1	69	75	PF00498	0.537
LIG_FHA_2	96	102	PF00498	0.657
LIG_LIR_Apic_2	54	59	PF02991	0.550
LIG_LIR_Gen_1	179	189	PF02991	0.728
LIG_LIR_Nem_3	179	185	PF02991	0.743
LIG_LIR_Nem_3	288	292	PF02991	0.751
LIG_LYPXL_yS_3	146	149	PF13949	0.526
LIG_SH2_CRK	182	186	PF00017	0.665
LIG_SH2_SRC	56	59	PF00017	0.564
LIG_SH2_STAP1	229	233	PF00017	0.694
LIG_SH2_STAT5	158	161	PF00017	0.818
LIG_SH2_STAT5	261	264	PF00017	0.709
LIG_SH2_STAT5	268	271	PF00017	0.795
LIG_SH3_3	137	143	PF00018	0.528
LIG_SH3_3	171	177	PF00018	0.532
LIG_SH3_3	222	228	PF00018	0.736
LIG_SH3_3	230	236	PF00018	0.522
LIG_SUMO_SIM_anti_2	136	141	PF11976	0.669
LIG_TRAF2_1	47	50	PF00917	0.769
LIG_WRC_WIRS_1	35	40	PF05994	0.643
MOD_CDK_SPxK_1	59	65	PF00069	0.818
MOD_CK1_1	198	204	PF00069	0.530
MOD_CK1_1	217	223	PF00069	0.598
MOD_CK1_1	252	258	PF00069	0.586
MOD_CK1_1	313	319	PF00069	0.766
MOD_CK1_1	41	47	PF00069	0.646
MOD_CK1_1	95	101	PF00069	0.527
MOD_CK2_1	44	50	PF00069	0.767
MOD_CK2_1	95	101	PF00069	0.648
MOD_Cter_Amidation	272	275	PF01082	0.801
MOD_GlcNHglycan	198	201	PF01048	0.694
MOD_GlcNHglycan	256	259	PF01048	0.705
MOD_GlcNHglycan	323	326	PF01048	0.769
MOD_GlcNHglycan	94	97	PF01048	0.659
MOD_GSK3_1	115	122	PF00069	0.661
MOD_GSK3_1	149	156	PF00069	0.542
MOD_GSK3_1	172	179	PF00069	0.664
MOD_GSK3_1	194	201	PF00069	0.682
MOD_GSK3_1	249	256	PF00069	0.738
MOD_GSK3_1	275	282	PF00069	0.655
MOD_GSK3_1	309	316	PF00069	0.728
MOD_GSK3_1	34	41	PF00069	0.493
MOD_GSK3_1	4	11	PF00069	0.709
MOD_LATS_1	160	166	PF00433	0.812
MOD_NEK2_1	148	153	PF00069	0.539
MOD_NEK2_1	196	201	PF00069	0.541
MOD_NEK2_1	319	324	PF00069	0.760
MOD_NEK2_1	38	43	PF00069	0.691
MOD_NEK2_2	243	248	PF00069	0.718
MOD_PKA_1	274	280	PF00069	0.619
MOD_PKA_2	119	125	PF00069	0.693
MOD_PKA_2	149	155	PF00069	0.541
MOD_PKA_2	183	189	PF00069	0.543
MOD_PKA_2	274	280	PF00069	0.619
MOD_Plk_1	217	223	PF00069	0.749
MOD_Plk_4	217	223	PF00069	0.749
MOD_Plk_4	243	249	PF00069	0.614
MOD_Plk_4	314	320	PF00069	0.763
MOD_Plk_4	38	44	PF00069	0.660
MOD_ProDKin_1	302	308	PF00069	0.539
MOD_ProDKin_1	4	10	PF00069	0.707
MOD_ProDKin_1	59	65	PF00069	0.818
MOD_SUMO_rev_2	110	118	PF00179	0.335
MOD_SUMO_rev_2	91	95	PF00179	0.683
TRG_DiLeu_BaLyEn_6	234	239	PF01217	0.696
TRG_DiLeu_BaLyEn_6	31	36	PF01217	0.600
TRG_ENDOCYTIC_2	146	149	PF00928	0.526
TRG_ENDOCYTIC_2	182	185	PF00928	0.729
TRG_ER_diArg_1	104	107	PF00400	0.655
TRG_ER_diArg_1	20	23	PF00400	0.662

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3Q8IHI6	Leishmania donovani	93%	100%
A4I930	Leishmania infantum	93%	100%
Q4Q429	Leishmania major	92%	100%