Unspecified product

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Unspecified product

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9B3W8_LEIMU

TriTrypDb:

LmxM.32.1320

Length:

265

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 9
NetGPI	no	yes: 0, no: 9

Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	1
GO:0110165	cellular anatomical entity	1	1

Expansion

Sequence features

E9B3W8

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B3W8

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	60	64	PF00656	0.660
CLV_MEL_PAP_1	222	228	PF00089	0.445
CLV_NRD_NRD_1	181	183	PF00675	0.674
CLV_NRD_NRD_1	93	95	PF00675	0.585
CLV_PCSK_KEX2_1	181	183	PF00082	0.538
CLV_PCSK_KEX2_1	95	97	PF00082	0.556
CLV_PCSK_PC1ET2_1	95	97	PF00082	0.514
CLV_PCSK_SKI1_1	113	117	PF00082	0.564
CLV_PCSK_SKI1_1	172	176	PF00082	0.561
CLV_PCSK_SKI1_1	211	215	PF00082	0.622
DOC_CKS1_1	82	87	PF01111	0.601
DOC_CYCLIN_RxL_1	208	216	PF00134	0.594
DOC_CYCLIN_yClb3_PxF_3	149	157	PF00134	0.659
DOC_PP1_RVXF_1	93	100	PF00149	0.563
DOC_PP2B_LxvP_1	261	264	PF13499	0.630
DOC_PP4_FxxP_1	118	121	PF00568	0.564
DOC_PP4_FxxP_1	246	249	PF00568	0.625
DOC_PP4_FxxP_1	257	260	PF00568	0.544
DOC_USP7_MATH_1	224	228	PF00917	0.450
DOC_USP7_MATH_1	77	81	PF00917	0.641
DOC_USP7_MATH_2	88	94	PF00917	0.578
DOC_WW_Pin1_4	134	139	PF00397	0.647
DOC_WW_Pin1_4	147	152	PF00397	0.556
DOC_WW_Pin1_4	187	192	PF00397	0.665
DOC_WW_Pin1_4	7	12	PF00397	0.659
DOC_WW_Pin1_4	81	86	PF00397	0.639
LIG_14-3-3_CanoR_1	225	233	PF00244	0.464
LIG_BIR_II_1	1	5	PF00653	0.743
LIG_FHA_1	148	154	PF00498	0.688
LIG_FHA_1	22	28	PF00498	0.453
LIG_FHA_1	32	38	PF00498	0.595
LIG_FHA_1	57	63	PF00498	0.675
LIG_FHA_2	188	194	PF00498	0.653
LIG_FHA_2	254	260	PF00498	0.550
LIG_LIR_Apic_2	116	121	PF02991	0.565
LIG_LIR_Apic_2	243	249	PF02991	0.592
LIG_LIR_Apic_2	254	260	PF02991	0.454
LIG_LIR_Nem_3	212	217	PF02991	0.612
LIG_MYND_1	260	264	PF01753	0.392
LIG_PDZ_Class_2	260	265	PF00595	0.520
LIG_Pex14_2	214	218	PF04695	0.639
LIG_Pex14_2	246	250	PF04695	0.583
LIG_SH2_NCK_1	130	134	PF00017	0.755
LIG_SH3_3	135	141	PF00018	0.690
LIG_SH3_3	146	152	PF00018	0.714
LIG_SH3_3	5	11	PF00018	0.657
LIG_SH3_3	79	85	PF00018	0.644
LIG_SH3_3	86	92	PF00018	0.707
LIG_SUMO_SIM_par_1	9	17	PF11976	0.755
LIG_TRAF2_1	2	5	PF00917	0.711
LIG_TRAF2_1	58	61	PF00917	0.661
LIG_TRFH_1	192	196	PF08558	0.608
MOD_CDC14_SPxK_1	137	140	PF00782	0.688
MOD_CDK_SPxK_1	134	140	PF00069	0.695
MOD_CDK_SPxK_1	81	87	PF00069	0.636
MOD_CK1_1	125	131	PF00069	0.697
MOD_CK1_1	160	166	PF00069	0.526
MOD_CK2_1	187	193	PF00069	0.657
MOD_CK2_1	253	259	PF00069	0.553
MOD_GlcNHglycan	204	207	PF01048	0.577
MOD_GSK3_1	125	132	PF00069	0.590
MOD_GSK3_1	157	164	PF00069	0.451
MOD_GSK3_1	200	207	PF00069	0.558
MOD_GSK3_1	234	241	PF00069	0.637
MOD_GSK3_1	77	84	PF00069	0.554
MOD_N-GLC_1	142	147	PF02516	0.639
MOD_N-GLC_1	234	239	PF02516	0.636
MOD_NEK2_1	202	207	PF00069	0.600
MOD_NEK2_1	218	223	PF00069	0.696
MOD_NEK2_2	209	214	PF00069	0.606
MOD_PIKK_1	238	244	PF00454	0.695
MOD_PKA_2	125	131	PF00069	0.701
MOD_PKA_2	139	145	PF00069	0.670
MOD_PKA_2	224	230	PF00069	0.463
MOD_PKB_1	232	240	PF00069	0.667
MOD_Plk_1	142	148	PF00069	0.647
MOD_Plk_1	160	166	PF00069	0.441
MOD_Plk_1	253	259	PF00069	0.553
MOD_Plk_4	209	215	PF00069	0.569
MOD_Plk_4	77	83	PF00069	0.659
MOD_ProDKin_1	134	140	PF00069	0.649
MOD_ProDKin_1	147	153	PF00069	0.551
MOD_ProDKin_1	187	193	PF00069	0.667
MOD_ProDKin_1	7	13	PF00069	0.659
MOD_ProDKin_1	81	87	PF00069	0.636
TRG_DiLeu_BaEn_1	61	66	PF01217	0.608
TRG_DiLeu_BaLyEn_6	257	262	PF01217	0.395
TRG_ER_diArg_1	180	182	PF00400	0.675
TRG_ER_diArg_1	231	234	PF00400	0.662
TRG_ER_diArg_1	94	97	PF00400	0.553
TRG_NLS_MonoExtN_4	92	98	PF00514	0.541

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P385	Leptomonas seymouri	56%	95%
A0A1X0P111	Trypanosomatidae	32%	75%
A0A3S7X6L8	Leishmania donovani	93%	100%
A0A422NCP6	Trypanosoma rangeli	29%	89%
A4HLJ1	Leishmania braziliensis	67%	94%
A4HLJ3	Leishmania braziliensis	68%	94%
A4I8Z9	Leishmania infantum	93%	100%
Q4Q456	Leishmania major	93%	100%