LeishMANIAdb
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Expression-site associated gene (ESAG3),putative

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Expression-site associated gene (ESAG3),putative
Gene product:
expression-site associated gene (ESAG3), putative
Species:
Leishmania mexicana
UniProt:
E9B3W7_LEIMU
TriTrypDb:
LmxM.32.1310
Length:
670

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 13
NetGPI no yes: 0, no: 13
Cellular components
TermNameLevelCount
GO:0016020 membrane 2 5
GO:0110165 cellular anatomical entity 1 5
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Expansion

Sequence features

E9B3W7
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B3W7

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_NRD_NRD_1 133 135 PF00675 0.593
CLV_NRD_NRD_1 155 157 PF00675 0.567
CLV_NRD_NRD_1 199 201 PF00675 0.604
CLV_NRD_NRD_1 237 239 PF00675 0.492
CLV_NRD_NRD_1 400 402 PF00675 0.543
CLV_NRD_NRD_1 501 503 PF00675 0.609
CLV_NRD_NRD_1 629 631 PF00675 0.610
CLV_NRD_NRD_1 76 78 PF00675 0.735
CLV_NRD_NRD_1 98 100 PF00675 0.591
CLV_PCSK_FUR_1 131 135 PF00082 0.564
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N1IGZ4 Leptomonas seymouri 61% 100%
A0A3Q8ID98 Leishmania donovani 33% 100%
A0A3Q8IM92 Leishmania donovani 91% 100%
A4H7X2 Leishmania braziliensis 32% 100%
A4HLI8 Leishmania braziliensis 79% 100%
A4HLJ0 Leishmania braziliensis 76% 100%
A4HLJ2 Leishmania braziliensis 80% 100%
A4HW99 Leishmania infantum 33% 100%
A4I8Z8 Leishmania infantum 91% 100%
E9APZ9 Leishmania mexicana (strain MHOM/GT/2001/U1103) 33% 100%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS