Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9B3W1_LEIMU

TriTrypDb:

LmxM.32.1260

Length:

941

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B3W1

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B3W1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	195	199	PF00656	0.532
CLV_C14_Caspase3-7	486	490	PF00656	0.640
CLV_C14_Caspase3-7	556	560	PF00656	0.654
CLV_C14_Caspase3-7	708	712	PF00656	0.677
CLV_NRD_NRD_1	11	13	PF00675	0.506
CLV_NRD_NRD_1	227	229	PF00675	0.694
CLV_NRD_NRD_1	308	310	PF00675	0.699
CLV_NRD_NRD_1	343	345	PF00675	0.625
CLV_NRD_NRD_1	376	378	PF00675	0.708
CLV_NRD_NRD_1	386	388	PF00675	0.600
CLV_NRD_NRD_1	39	41	PF00675	0.560
CLV_NRD_NRD_1	434	436	PF00675	0.659
CLV_NRD_NRD_1	516	518	PF00675	0.569
CLV_NRD_NRD_1	567	569	PF00675	0.640
CLV_NRD_NRD_1	651	653	PF00675	0.720
CLV_NRD_NRD_1	744	746	PF00675	0.572
CLV_NRD_NRD_1	755	757	PF00675	0.539
CLV_NRD_NRD_1	795	797	PF00675	0.677
CLV_NRD_NRD_1	844	846	PF00675	0.682
CLV_NRD_NRD_1	94	96	PF00675	0.451
CLV_PCSK_FUR_1	741	745	PF00082	0.558
CLV_PCSK_KEX2_1	13	15	PF00082	0.502
CLV_PCSK_KEX2_1	227	229	PF00082	0.694
CLV_PCSK_KEX2_1	343	345	PF00082	0.511
CLV_PCSK_KEX2_1	369	371	PF00082	0.694
CLV_PCSK_KEX2_1	376	378	PF00082	0.643
CLV_PCSK_KEX2_1	386	388	PF00082	0.534
CLV_PCSK_KEX2_1	39	41	PF00082	0.560
CLV_PCSK_KEX2_1	453	455	PF00082	0.537
CLV_PCSK_KEX2_1	516	518	PF00082	0.569
CLV_PCSK_KEX2_1	567	569	PF00082	0.628
CLV_PCSK_KEX2_1	650	652	PF00082	0.720
CLV_PCSK_KEX2_1	743	745	PF00082	0.568
CLV_PCSK_KEX2_1	755	757	PF00082	0.538
CLV_PCSK_KEX2_1	844	846	PF00082	0.682
CLV_PCSK_KEX2_1	94	96	PF00082	0.451
CLV_PCSK_PC1ET2_1	13	15	PF00082	0.469
CLV_PCSK_PC1ET2_1	369	371	PF00082	0.694
CLV_PCSK_PC1ET2_1	453	455	PF00082	0.520
CLV_PCSK_PC7_1	840	846	PF00082	0.617
CLV_PCSK_PC7_1	90	96	PF00082	0.435
CLV_PCSK_SKI1_1	13	17	PF00082	0.462
CLV_PCSK_SKI1_1	228	232	PF00082	0.589
CLV_PCSK_SKI1_1	448	452	PF00082	0.563
CLV_PCSK_SKI1_1	506	510	PF00082	0.645
CLV_PCSK_SKI1_1	60	64	PF00082	0.505
CLV_PCSK_SKI1_1	652	656	PF00082	0.673
CLV_PCSK_SKI1_1	920	924	PF00082	0.575
DEG_APCC_DBOX_1	11	19	PF00400	0.461
DEG_APCC_DBOX_1	651	659	PF00400	0.713
DEG_Nend_UBRbox_2	1	3	PF02207	0.648
DEG_SCF_FBW7_1	1	8	PF00400	0.566
DOC_CDC14_PxL_1	614	622	PF14671	0.602
DOC_CDC14_PxL_1	798	806	PF14671	0.550
DOC_CKS1_1	185	190	PF01111	0.372
DOC_CKS1_1	299	304	PF01111	0.660
DOC_CKS1_1	608	613	PF01111	0.705
DOC_CKS1_1	869	874	PF01111	0.562
DOC_CKS1_1	910	915	PF01111	0.662
DOC_CKS1_1	931	936	PF01111	0.653
DOC_CYCLIN_RxL_1	407	418	PF00134	0.607
DOC_CYCLIN_yCln2_LP_2	615	621	PF00134	0.535
DOC_CYCLIN_yCln2_LP_2	658	664	PF00134	0.652
DOC_CYCLIN_yCln2_LP_2	804	810	PF00134	0.535
DOC_MAPK_gen_1	12	18	PF00069	0.447
DOC_MAPK_gen_1	492	499	PF00069	0.646
DOC_MAPK_MEF2A_6	492	499	PF00069	0.646
DOC_PP2B_LxvP_1	497	500	PF13499	0.642
DOC_PP2B_LxvP_1	574	577	PF13499	0.541
DOC_PP2B_LxvP_1	615	618	PF13499	0.544
DOC_PP4_FxxP_1	185	188	PF00568	0.489
DOC_PP4_MxPP_1	222	225	PF00568	0.649
DOC_USP7_MATH_1	158	162	PF00917	0.504
DOC_USP7_MATH_1	166	170	PF00917	0.438
DOC_USP7_MATH_1	192	196	PF00917	0.523
DOC_USP7_MATH_1	252	256	PF00917	0.707
DOC_USP7_MATH_1	265	269	PF00917	0.585
DOC_USP7_MATH_1	292	296	PF00917	0.702
DOC_USP7_MATH_1	346	350	PF00917	0.608
DOC_USP7_MATH_1	5	9	PF00917	0.560
DOC_USP7_MATH_1	582	586	PF00917	0.671
DOC_USP7_MATH_1	823	827	PF00917	0.648
DOC_USP7_MATH_1	925	929	PF00917	0.629
DOC_WW_Pin1_4	1	6	PF00397	0.599
DOC_WW_Pin1_4	133	138	PF00397	0.628
DOC_WW_Pin1_4	184	189	PF00397	0.385
DOC_WW_Pin1_4	220	225	PF00397	0.652
DOC_WW_Pin1_4	256	261	PF00397	0.544
DOC_WW_Pin1_4	298	303	PF00397	0.653
DOC_WW_Pin1_4	304	309	PF00397	0.624
DOC_WW_Pin1_4	355	360	PF00397	0.622
DOC_WW_Pin1_4	379	384	PF00397	0.707
DOC_WW_Pin1_4	400	405	PF00397	0.643
DOC_WW_Pin1_4	415	420	PF00397	0.586
DOC_WW_Pin1_4	473	478	PF00397	0.700
DOC_WW_Pin1_4	597	602	PF00397	0.716
DOC_WW_Pin1_4	604	609	PF00397	0.715
DOC_WW_Pin1_4	697	702	PF00397	0.687
DOC_WW_Pin1_4	726	731	PF00397	0.539
DOC_WW_Pin1_4	755	760	PF00397	0.589
DOC_WW_Pin1_4	768	773	PF00397	0.632
DOC_WW_Pin1_4	774	779	PF00397	0.601
DOC_WW_Pin1_4	810	815	PF00397	0.586
DOC_WW_Pin1_4	838	843	PF00397	0.660
DOC_WW_Pin1_4	844	849	PF00397	0.630
DOC_WW_Pin1_4	854	859	PF00397	0.559
DOC_WW_Pin1_4	860	865	PF00397	0.563
DOC_WW_Pin1_4	868	873	PF00397	0.582
DOC_WW_Pin1_4	886	891	PF00397	0.565
DOC_WW_Pin1_4	909	914	PF00397	0.663
DOC_WW_Pin1_4	921	926	PF00397	0.549
DOC_WW_Pin1_4	930	935	PF00397	0.584
LIG_14-3-3_CanoR_1	159	165	PF00244	0.461
LIG_14-3-3_CanoR_1	180	186	PF00244	0.384
LIG_14-3-3_CanoR_1	227	233	PF00244	0.567
LIG_14-3-3_CanoR_1	343	353	PF00244	0.626
LIG_14-3-3_CanoR_1	370	379	PF00244	0.621
LIG_14-3-3_CanoR_1	386	395	PF00244	0.578
LIG_14-3-3_CanoR_1	448	453	PF00244	0.560
LIG_14-3-3_CanoR_1	460	469	PF00244	0.594
LIG_14-3-3_CanoR_1	55	60	PF00244	0.466
LIG_14-3-3_CanoR_1	567	573	PF00244	0.711
LIG_14-3-3_CanoR_1	73	83	PF00244	0.554
LIG_14-3-3_CanoR_1	822	830	PF00244	0.649
LIG_14-3-3_CanoR_1	831	835	PF00244	0.596
LIG_14-3-3_CanoR_1	856	862	PF00244	0.656
LIG_14-3-3_CanoR_1	905	911	PF00244	0.677
LIG_BIR_III_2	474	478	PF00653	0.661
LIG_BIR_III_4	157	161	PF00653	0.464
LIG_BRCT_BRCA1_1	812	816	PF00533	0.650
LIG_CtBP_PxDLS_1	934	938	PF00389	0.602
LIG_DLG_GKlike_1	55	62	PF00625	0.490
LIG_FHA_1	112	118	PF00498	0.465
LIG_FHA_1	185	191	PF00498	0.382
LIG_FHA_1	221	227	PF00498	0.651
LIG_FHA_1	403	409	PF00498	0.567
LIG_FHA_1	474	480	PF00498	0.707
LIG_FHA_1	857	863	PF00498	0.675
LIG_FHA_1	917	923	PF00498	0.645
LIG_FHA_2	145	151	PF00498	0.626
LIG_FHA_2	484	490	PF00498	0.611
LIG_FHA_2	527	533	PF00498	0.649
LIG_FHA_2	663	669	PF00498	0.693
LIG_FHA_2	702	708	PF00498	0.673
LIG_FHA_2	734	740	PF00498	0.612
LIG_FHA_2	831	837	PF00498	0.659
LIG_GSK3_LRP6_1	604	610	PF00069	0.606
LIG_LIR_Apic_2	184	188	PF02991	0.497
LIG_LIR_Apic_2	297	303	PF02991	0.666
LIG_LIR_Apic_2	354	360	PF02991	0.629
LIG_LIR_Gen_1	161	172	PF02991	0.486
LIG_LIR_Nem_3	161	167	PF02991	0.498
LIG_LIR_Nem_3	57	62	PF02991	0.489
LIG_MLH1_MIPbox_1	812	816	PF16413	0.530
LIG_MYND_1	810	814	PF01753	0.645
LIG_MYND_1	935	939	PF01753	0.604
LIG_Pex14_2	181	185	PF04695	0.550
LIG_Pex14_2	353	357	PF04695	0.516
LIG_Pex14_2	59	63	PF04695	0.481
LIG_Rb_pABgroove_1	170	178	PF01858	0.444
LIG_REV1ctd_RIR_1	339	348	PF16727	0.508
LIG_SH2_CRK	22	26	PF00017	0.357
LIG_SH2_CRK	300	304	PF00017	0.714
LIG_SH2_GRB2like	232	235	PF00017	0.716
LIG_SH2_NCK_1	300	304	PF00017	0.550
LIG_SH2_SRC	232	235	PF00017	0.716
LIG_SH2_STAP1	22	26	PF00017	0.478
LIG_SH2_STAP1	232	236	PF00017	0.609
LIG_SH2_STAT3	176	179	PF00017	0.434
LIG_SH2_STAT5	174	177	PF00017	0.592
LIG_SH2_STAT5	300	303	PF00017	0.714
LIG_SH2_STAT5	462	465	PF00017	0.617
LIG_SH3_1	300	306	PF00018	0.709
LIG_SH3_1	413	419	PF00018	0.698
LIG_SH3_2	249	254	PF14604	0.535
LIG_SH3_2	305	310	PF14604	0.634
LIG_SH3_2	618	623	PF14604	0.592
LIG_SH3_3	246	252	PF00018	0.531
LIG_SH3_3	271	277	PF00018	0.533
LIG_SH3_3	296	302	PF00018	0.698
LIG_SH3_3	382	388	PF00018	0.646
LIG_SH3_3	413	419	PF00018	0.698
LIG_SH3_3	466	472	PF00018	0.657
LIG_SH3_3	496	502	PF00018	0.685
LIG_SH3_3	598	604	PF00018	0.787
LIG_SH3_3	605	611	PF00018	0.689
LIG_SH3_3	615	621	PF00018	0.647
LIG_SH3_3	666	672	PF00018	0.700
LIG_SH3_3	724	730	PF00018	0.645
LIG_SH3_3	766	772	PF00018	0.527
LIG_SH3_3	804	810	PF00018	0.638
LIG_SH3_3	866	872	PF00018	0.593
LIG_SH3_3	911	917	PF00018	0.656
LIG_SH3_3	928	934	PF00018	0.517
LIG_SH3_CIN85_PxpxPR_1	701	706	PF14604	0.624
LIG_SUMO_SIM_anti_2	169	174	PF11976	0.430
LIG_SUMO_SIM_anti_2	331	336	PF11976	0.670
LIG_TRAF2_1	637	640	PF00917	0.666
LIG_UBA3_1	544	548	PF00899	0.643
LIG_WRC_WIRS_1	350	355	PF05994	0.512
LIG_WRC_WIRS_1	56	61	PF05994	0.495
LIG_WW_3	890	894	PF00397	0.670
LIG_WW_3	912	916	PF00397	0.653
MOD_CDC14_SPxK_1	307	310	PF00782	0.557
MOD_CDC14_SPxK_1	384	387	PF00782	0.647
MOD_CDC14_SPxK_1	600	603	PF00782	0.642
MOD_CDK_SPK_2	304	309	PF00069	0.540
MOD_CDK_SPK_2	381	386	PF00069	0.697
MOD_CDK_SPK_2	701	706	PF00069	0.624
MOD_CDK_SPxK_1	304	310	PF00069	0.573
MOD_CDK_SPxK_1	381	387	PF00069	0.653
MOD_CDK_SPxK_1	597	603	PF00069	0.647
MOD_CDK_SPxK_1	838	844	PF00069	0.663
MOD_CDK_SPxK_1	909	915	PF00069	0.663
MOD_CDK_SPxxK_3	220	227	PF00069	0.649
MOD_CDK_SPxxK_3	379	386	PF00069	0.702
MOD_CDK_SPxxK_3	699	706	PF00069	0.626
MOD_CDK_SPxxK_3	838	845	PF00069	0.666
MOD_CDK_SPxxK_3	860	867	PF00069	0.679
MOD_CDK_SPxxK_3	886	893	PF00069	0.677
MOD_CK1_1	136	142	PF00069	0.590
MOD_CK1_1	146	152	PF00069	0.591
MOD_CK1_1	184	190	PF00069	0.378
MOD_CK1_1	259	265	PF00069	0.581
MOD_CK1_1	304	310	PF00069	0.583
MOD_CK1_1	349	355	PF00069	0.666
MOD_CK1_1	358	364	PF00069	0.593
MOD_CK1_1	520	526	PF00069	0.570
MOD_CK1_1	607	613	PF00069	0.707
MOD_CK1_1	777	783	PF00069	0.655
MOD_CK1_1	784	790	PF00069	0.609
MOD_CK1_1	860	866	PF00069	0.640
MOD_CK1_1	874	880	PF00069	0.579
MOD_CK2_1	144	150	PF00069	0.704
MOD_CK2_1	526	532	PF00069	0.646
MOD_CK2_1	634	640	PF00069	0.667
MOD_CK2_1	662	668	PF00069	0.694
MOD_CK2_1	701	707	PF00069	0.712
MOD_CK2_1	733	739	PF00069	0.617
MOD_CK2_1	784	790	PF00069	0.672
MOD_Cter_Amidation	565	568	PF01082	0.632
MOD_DYRK1A_RPxSP_1	415	419	PF00069	0.637
MOD_GlcNHglycan	234	237	PF01048	0.627
MOD_GlcNHglycan	254	257	PF01048	0.528
MOD_GlcNHglycan	335	338	PF01048	0.631
MOD_GlcNHglycan	346	349	PF01048	0.554
MOD_GlcNHglycan	360	363	PF01048	0.614
MOD_GlcNHglycan	379	382	PF01048	0.537
MOD_GlcNHglycan	389	392	PF01048	0.583
MOD_GlcNHglycan	454	457	PF01048	0.516
MOD_GlcNHglycan	559	562	PF01048	0.601
MOD_GlcNHglycan	574	577	PF01048	0.559
MOD_GlcNHglycan	580	583	PF01048	0.664
MOD_GlcNHglycan	715	718	PF01048	0.661
MOD_GlcNHglycan	721	725	PF01048	0.618
MOD_GlcNHglycan	825	828	PF01048	0.651
MOD_GlcNHglycan	925	928	PF01048	0.628
MOD_GSK3_1	1	8	PF00069	0.582
MOD_GSK3_1	228	235	PF00069	0.626
MOD_GSK3_1	252	259	PF00069	0.708
MOD_GSK3_1	265	272	PF00069	0.584
MOD_GSK3_1	344	351	PF00069	0.609
MOD_GSK3_1	377	384	PF00069	0.664
MOD_GSK3_1	417	424	PF00069	0.536
MOD_GSK3_1	448	455	PF00069	0.535
MOD_GSK3_1	551	558	PF00069	0.713
MOD_GSK3_1	568	575	PF00069	0.554
MOD_GSK3_1	578	585	PF00069	0.663
MOD_GSK3_1	697	704	PF00069	0.715
MOD_GSK3_1	74	81	PF00069	0.493
MOD_GSK3_1	768	775	PF00069	0.645
MOD_GSK3_1	777	784	PF00069	0.611
MOD_GSK3_1	840	847	PF00069	0.643
MOD_GSK3_1	856	863	PF00069	0.593
MOD_GSK3_1	871	878	PF00069	0.578
MOD_GSK3_1	921	928	PF00069	0.631
MOD_GSK3_1	929	936	PF00069	0.592
MOD_N-GLC_1	540	545	PF02516	0.513
MOD_N-GLC_1	780	785	PF02516	0.679
MOD_NEK2_1	181	186	PF00069	0.600
MOD_NEK2_1	202	207	PF00069	0.601
MOD_NEK2_1	269	274	PF00069	0.664
MOD_NEK2_1	353	358	PF00069	0.551
MOD_NEK2_1	41	46	PF00069	0.469
MOD_NEK2_1	461	466	PF00069	0.710
MOD_NEK2_1	572	577	PF00069	0.545
MOD_NEK2_1	626	631	PF00069	0.585
MOD_NEK2_1	773	778	PF00069	0.540
MOD_NEK2_1	816	821	PF00069	0.652
MOD_NEK2_1	830	835	PF00069	0.559
MOD_NEK2_1	929	934	PF00069	0.642
MOD_NEK2_2	587	592	PF00069	0.557
MOD_PIKK_1	417	423	PF00454	0.694
MOD_PIKK_1	643	649	PF00454	0.655
MOD_PIKK_1	733	739	PF00454	0.671
MOD_PIKK_1	74	80	PF00454	0.544
MOD_PK_1	899	905	PF00069	0.673
MOD_PKA_1	228	234	PF00069	0.620
MOD_PKA_1	567	573	PF00069	0.655
MOD_PKA_2	158	164	PF00069	0.472
MOD_PKA_2	437	443	PF00069	0.688
MOD_PKA_2	54	60	PF00069	0.510
MOD_PKA_2	566	572	PF00069	0.686
MOD_PKA_2	596	602	PF00069	0.656
MOD_PKA_2	678	684	PF00069	0.651
MOD_PKA_2	781	787	PF00069	0.677
MOD_PKA_2	830	836	PF00069	0.541
MOD_PKA_2	892	898	PF00069	0.681
MOD_PKA_2	904	910	PF00069	0.591
MOD_Plk_1	41	47	PF00069	0.388
MOD_Plk_1	540	546	PF00069	0.514
MOD_Plk_1	720	726	PF00069	0.660
MOD_Plk_2-3	540	546	PF00069	0.635
MOD_Plk_2-3	634	640	PF00069	0.613
MOD_Plk_4	166	172	PF00069	0.511
MOD_Plk_4	181	187	PF00069	0.501
MOD_Plk_4	21	27	PF00069	0.405
MOD_Plk_4	540	546	PF00069	0.635
MOD_Plk_4	830	836	PF00069	0.659
MOD_Plk_4	857	863	PF00069	0.675
MOD_ProDKin_1	1	7	PF00069	0.579
MOD_ProDKin_1	133	139	PF00069	0.628
MOD_ProDKin_1	184	190	PF00069	0.378
MOD_ProDKin_1	220	226	PF00069	0.653
MOD_ProDKin_1	256	262	PF00069	0.545
MOD_ProDKin_1	298	304	PF00069	0.654
MOD_ProDKin_1	355	361	PF00069	0.623
MOD_ProDKin_1	379	385	PF00069	0.700
MOD_ProDKin_1	400	406	PF00069	0.636
MOD_ProDKin_1	415	421	PF00069	0.587
MOD_ProDKin_1	473	479	PF00069	0.701
MOD_ProDKin_1	597	603	PF00069	0.719
MOD_ProDKin_1	604	610	PF00069	0.715
MOD_ProDKin_1	697	703	PF00069	0.685
MOD_ProDKin_1	726	732	PF00069	0.540
MOD_ProDKin_1	755	761	PF00069	0.588
MOD_ProDKin_1	768	774	PF00069	0.633
MOD_ProDKin_1	810	816	PF00069	0.588
MOD_ProDKin_1	838	844	PF00069	0.663
MOD_ProDKin_1	854	860	PF00069	0.559
MOD_ProDKin_1	868	874	PF00069	0.582
MOD_ProDKin_1	886	892	PF00069	0.565
MOD_ProDKin_1	909	915	PF00069	0.663
MOD_ProDKin_1	921	927	PF00069	0.547
MOD_ProDKin_1	930	936	PF00069	0.587
MOD_SUMO_for_1	675	678	PF00179	0.537
MOD_SUMO_rev_2	518	526	PF00179	0.644
MOD_SUMO_rev_2	540	549	PF00179	0.641
MOD_SUMO_rev_2	790	799	PF00179	0.675
TRG_DiLeu_BaEn_1	540	545	PF01217	0.634
TRG_DiLeu_BaLyEn_6	11	16	PF01217	0.458
TRG_ENDOCYTIC_2	22	25	PF00928	0.348
TRG_ER_diArg_1	11	14	PF00400	0.480
TRG_ER_diArg_1	226	228	PF00400	0.696
TRG_ER_diArg_1	342	344	PF00400	0.513
TRG_ER_diArg_1	38	40	PF00400	0.632
TRG_ER_diArg_1	385	387	PF00400	0.645
TRG_ER_diArg_1	412	415	PF00400	0.650
TRG_ER_diArg_1	650	652	PF00400	0.720
TRG_ER_diArg_1	740	743	PF00400	0.539
TRG_ER_diArg_1	754	756	PF00400	0.547
TRG_ER_diArg_1	844	846	PF00400	0.682
TRG_ER_diArg_1	93	95	PF00400	0.457
TRG_Pf-PMV_PEXEL_1	82	86	PF00026	0.409

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3Q8IDQ6	Leishmania donovani	78%	96%
A4HLI2	Leishmania braziliensis	51%	99%
A4I8Z2	Leishmania infantum	78%	96%
Q4Q463	Leishmania major	78%	100%