Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9B3V9_LEIMU

TriTrypDb:

LmxM.32.1245

Length:

396

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 4
NetGPI	no	yes: 0, no: 4

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B3V9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B3V9

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	303	305	PF00675	0.811
CLV_NRD_NRD_1	351	353	PF00675	0.791
CLV_NRD_NRD_1	380	382	PF00675	0.634
CLV_NRD_NRD_1	385	387	PF00675	0.714
CLV_NRD_NRD_1	73	75	PF00675	0.771
CLV_PCSK_KEX2_1	303	305	PF00082	0.811
CLV_PCSK_KEX2_1	351	353	PF00082	0.791
CLV_PCSK_KEX2_1	380	382	PF00082	0.634
CLV_PCSK_KEX2_1	385	387	PF00082	0.714
CLV_PCSK_PC1ET2_1	303	305	PF00082	0.811
CLV_PCSK_PC7_1	381	387	PF00082	0.701
DEG_Nend_UBRbox_3	1	3	PF02207	0.547
DOC_CYCLIN_yCln2_LP_2	204	210	PF00134	0.842
DOC_MAPK_MEF2A_6	46	54	PF00069	0.809
DOC_PP2B_LxvP_1	204	207	PF13499	0.844
DOC_PP2B_LxvP_1	217	220	PF13499	0.619
DOC_PP4_FxxP_1	388	391	PF00568	0.726
DOC_PP4_FxxP_1	4	7	PF00568	0.755
DOC_USP7_MATH_1	163	167	PF00917	0.793
DOC_USP7_MATH_1	220	224	PF00917	0.680
DOC_USP7_MATH_1	311	315	PF00917	0.692
DOC_USP7_MATH_1	32	36	PF00917	0.687
DOC_USP7_MATH_1	326	330	PF00917	0.527
DOC_USP7_MATH_1	345	349	PF00917	0.504
DOC_USP7_MATH_1	65	69	PF00917	0.801
DOC_USP7_MATH_1	88	92	PF00917	0.807
DOC_USP7_UBL2_3	62	66	PF12436	0.819
DOC_WW_Pin1_4	133	138	PF00397	0.778
DOC_WW_Pin1_4	158	163	PF00397	0.683
DOC_WW_Pin1_4	194	199	PF00397	0.842
DOC_WW_Pin1_4	218	223	PF00397	0.663
DOC_WW_Pin1_4	245	250	PF00397	0.794
DOC_WW_Pin1_4	269	274	PF00397	0.760
DOC_WW_Pin1_4	30	35	PF00397	0.678
DOC_WW_Pin1_4	324	329	PF00397	0.761
DOC_WW_Pin1_4	82	87	PF00397	0.772
DOC_WW_Pin1_4	89	94	PF00397	0.659
LIG_14-3-3_CanoR_1	351	360	PF00244	0.793
LIG_BRCT_BRCA1_1	326	330	PF00533	0.770
LIG_BRCT_BRCA1_1	54	58	PF00533	0.804
LIG_FHA_1	128	134	PF00498	0.845
LIG_FHA_1	214	220	PF00498	0.807
LIG_FHA_1	253	259	PF00498	0.653
LIG_FHA_2	260	266	PF00498	0.468
LIG_LIR_Apic_2	288	294	PF02991	0.790
LIG_LIR_Apic_2	3	7	PF02991	0.740
LIG_LIR_Nem_3	371	377	PF02991	0.727
LIG_MYND_1	294	298	PF01753	0.791
LIG_Pex14_1	318	322	PF04695	0.749
LIG_Pex14_1	369	373	PF04695	0.747
LIG_SH2_STAP1	145	149	PF00017	0.688
LIG_SH2_STAT3	322	325	PF00017	0.606
LIG_SH2_STAT5	145	148	PF00017	0.687
LIG_SH2_STAT5	269	272	PF00017	0.622
LIG_SH2_STAT5	382	385	PF00017	0.690
LIG_SH2_STAT5	387	390	PF00017	0.655
LIG_SH3_2	298	303	PF14604	0.534
LIG_SH3_3	10	16	PF00018	0.644
LIG_SH3_3	101	107	PF00018	0.711
LIG_SH3_3	114	120	PF00018	0.592
LIG_SH3_3	136	142	PF00018	0.641
LIG_SH3_3	156	162	PF00018	0.828
LIG_SH3_3	164	170	PF00018	0.788
LIG_SH3_3	18	24	PF00018	0.503
LIG_SH3_3	188	194	PF00018	0.813
LIG_SH3_3	2	8	PF00018	0.766
LIG_SH3_3	274	280	PF00018	0.771
LIG_SH3_3	28	34	PF00018	0.515
LIG_SH3_3	289	295	PF00018	0.550
LIG_SH3_3	41	47	PF00018	0.519
LIG_SH3_3	91	97	PF00018	0.851
LIG_TRFH_1	269	273	PF08558	0.623
LIG_TRFH_1	322	326	PF08558	0.742
LIG_WRC_WIRS_1	1	6	PF05994	0.650
LIG_WW_1	142	145	PF00397	0.537
LIG_WW_2	191	194	PF00397	0.570
MOD_CDK_SPK_2	82	87	PF00069	0.853
MOD_CK1_1	127	133	PF00069	0.765
MOD_CK1_1	144	150	PF00069	0.713
MOD_CK1_1	184	190	PF00069	0.719
MOD_CK1_1	209	215	PF00069	0.705
MOD_CK1_1	245	251	PF00069	0.612
MOD_CK1_1	82	88	PF00069	0.853
MOD_CK2_1	259	265	PF00069	0.466
MOD_GlcNHglycan	101	104	PF01048	0.596
MOD_GlcNHglycan	146	149	PF01048	0.732
MOD_GlcNHglycan	183	186	PF01048	0.730
MOD_GlcNHglycan	208	211	PF01048	0.838
MOD_GlcNHglycan	226	229	PF01048	0.686
MOD_GlcNHglycan	308	311	PF01048	0.801
MOD_GlcNHglycan	313	316	PF01048	0.694
MOD_GlcNHglycan	34	37	PF01048	0.737
MOD_GlcNHglycan	347	350	PF01048	0.682
MOD_GlcNHglycan	361	364	PF01048	0.630
MOD_GlcNHglycan	77	80	PF01048	0.755
MOD_GlcNHglycan	81	84	PF01048	0.839
MOD_GSK3_1	127	134	PF00069	0.835
MOD_GSK3_1	143	150	PF00069	0.558
MOD_GSK3_1	154	161	PF00069	0.549
MOD_GSK3_1	177	184	PF00069	0.779
MOD_GSK3_1	208	215	PF00069	0.705
MOD_GSK3_1	220	227	PF00069	0.604
MOD_GSK3_1	240	247	PF00069	0.757
MOD_GSK3_1	269	276	PF00069	0.761
MOD_GSK3_1	32	39	PF00069	0.556
MOD_GSK3_1	340	347	PF00069	0.815
MOD_GSK3_1	355	362	PF00069	0.549
MOD_GSK3_1	75	82	PF00069	0.680
MOD_N-GLC_1	224	229	PF02516	0.547
MOD_N-GLC_1	89	94	PF02516	0.853
MOD_NEK2_1	244	249	PF00069	0.637
MOD_NEK2_1	52	57	PF00069	0.656
MOD_NEK2_1	81	86	PF00069	0.799
MOD_PKA_1	75	81	PF00069	0.674
MOD_PKA_2	124	130	PF00069	0.832
MOD_PKA_2	369	375	PF00069	0.748
MOD_Plk_4	259	265	PF00069	0.547
MOD_Plk_4	273	279	PF00069	0.732
MOD_Plk_4	355	361	PF00069	0.606
MOD_Plk_4	369	375	PF00069	0.710
MOD_ProDKin_1	133	139	PF00069	0.775
MOD_ProDKin_1	158	164	PF00069	0.683
MOD_ProDKin_1	194	200	PF00069	0.842
MOD_ProDKin_1	218	224	PF00069	0.662
MOD_ProDKin_1	245	251	PF00069	0.789
MOD_ProDKin_1	269	275	PF00069	0.763
MOD_ProDKin_1	30	36	PF00069	0.681
MOD_ProDKin_1	324	330	PF00069	0.761
MOD_ProDKin_1	82	88	PF00069	0.772
MOD_ProDKin_1	89	95	PF00069	0.659
MOD_SUMO_rev_2	68	77	PF00179	0.779
TRG_ER_diArg_1	379	381	PF00400	0.621
TRG_ER_diArg_1	385	387	PF00400	0.711
TRG_NLS_MonoCore_2	302	307	PF00514	0.809
TRG_NLS_MonoExtC_3	303	308	PF00514	0.674
TRG_NLS_MonoExtN_4	300	307	PF00514	0.807

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3Q8ITZ0	Leishmania donovani	87%	70%
A4I8Z0	Leishmania infantum	87%	98%
Q4Q465	Leishmania major	83%	100%