LeishMANIAdb
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Succinate dehydrogenase [ubiquinone] cytochrome b small subunit

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Succinate dehydrogenase [ubiquinone] cytochrome b small subunit
Gene product:
hypothetical protein, conserved
Species:
Leishmania mexicana
UniProt:
E9B3V0_LEIMU
TriTrypDb:
LmxM.32.1160
Length:
147

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 9
NetGPI no yes: 0, no: 9
Cellular components
Term Name Level Count
GO:0016020 membrane 2 9
GO:0110165 cellular anatomical entity 1 9
GO:0005737 cytoplasm 2 1

Expansion

Sequence features

E9B3V0
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B3V0

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_PCSK_KEX2_1 54 56 PF00082 0.651
CLV_PCSK_PC1ET2_1 54 56 PF00082 0.674
CLV_PCSK_SKI1_1 18 22 PF00082 0.658
CLV_PCSK_SKI1_1 5 9 PF00082 0.643
DEG_Nend_Nbox_1 1 3 PF02207 0.452
DOC_CYCLIN_RxL_1 2 12 PF00134 0.502
DOC_PP1_RVXF_1 11 17 PF00149 0.441
DOC_USP7_MATH_1 3 7 PF00917 0.494
DOC_USP7_MATH_1 45 49 PF00917 0.559
DOC_USP7_MATH_1 75 79 PF00917 0.500
DOC_WW_Pin1_4 82 87 PF00397 0.325
LIG_14-3-3_CanoR_1 44 52 PF00244 0.449
LIG_Clathr_ClatBox_1 137 141 PF01394 0.344
LIG_FHA_2 112 118 PF00498 0.594
LIG_LIR_Gen_1 141 147 PF02991 0.369
LIG_LIR_Nem_3 141 147 PF02991 0.369
LIG_LIR_Nem_3 81 87 PF02991 0.294
LIG_PDZ_Class_2 142 147 PF00595 0.539
LIG_SH2_CRK 130 134 PF00017 0.401
LIG_SH2_CRK 84 88 PF00017 0.344
LIG_SH2_CRK 97 101 PF00017 0.369
LIG_SH2_NCK_1 84 88 PF00017 0.401
LIG_SH2_STAP1 109 113 PF00017 0.578
LIG_SH2_STAT5 118 121 PF00017 0.610
LIG_SH2_STAT5 57 60 PF00017 0.483
LIG_SUMO_SIM_par_1 98 104 PF11976 0.357
LIG_TYR_ITIM 82 87 PF00017 0.344
LIG_TYR_ITIM 95 100 PF00017 0.369
MOD_CK1_1 36 42 PF00069 0.506
MOD_CK1_1 48 54 PF00069 0.450
MOD_CK1_1 78 84 PF00069 0.438
MOD_GlcNHglycan 39 42 PF01048 0.716
MOD_GlcNHglycan 47 50 PF01048 0.703
MOD_GSK3_1 107 114 PF00069 0.580
MOD_GSK3_1 29 36 PF00069 0.470
MOD_GSK3_1 3 10 PF00069 0.501
MOD_GSK3_1 40 47 PF00069 0.426
MOD_GSK3_1 74 81 PF00069 0.446
MOD_GSK3_1 82 89 PF00069 0.353
MOD_N-GLC_1 107 112 PF02516 0.412
MOD_NEK2_1 111 116 PF00069 0.599
MOD_NEK2_1 29 34 PF00069 0.539
MOD_NEK2_1 50 55 PF00069 0.482
MOD_NEK2_1 58 63 PF00069 0.456
MOD_NEK2_1 7 12 PF00069 0.490
MOD_PIKK_1 68 74 PF00454 0.439
MOD_PIKK_1 7 13 PF00454 0.501
MOD_PKA_2 29 35 PF00069 0.503
MOD_Plk_1 107 113 PF00069 0.595
MOD_Plk_4 58 64 PF00069 0.475
MOD_Plk_4 78 84 PF00069 0.415
MOD_ProDKin_1 82 88 PF00069 0.325
TRG_ENDOCYTIC_2 130 133 PF00928 0.344
TRG_ENDOCYTIC_2 84 87 PF00928 0.344
TRG_ENDOCYTIC_2 97 100 PF00928 0.369

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1PAG2 Leptomonas seymouri 73% 100%
A0A0S4JA46 Bodo saltans 35% 100%
A0A1X0P172 Trypanosomatidae 47% 100%
A0A3S5H7U3 Leishmania donovani 91% 100%
A0A422MW56 Trypanosoma rangeli 49% 100%
A4HLH1 Leishmania braziliensis 81% 100%
A4I8Y1 Leishmania infantum 91% 100%
Q4Q474 Leishmania major 88% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS