CCDC92 domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9B3U6_LEIMU

TriTrypDb:

LmxM.32.1120

Length:

322

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B3U6

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B3U6

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	134	138	PF00656	0.643
CLV_NRD_NRD_1	100	102	PF00675	0.548
CLV_NRD_NRD_1	206	208	PF00675	0.687
CLV_NRD_NRD_1	23	25	PF00675	0.590
CLV_NRD_NRD_1	283	285	PF00675	0.518
CLV_PCSK_FUR_1	21	25	PF00082	0.556
CLV_PCSK_KEX2_1	143	145	PF00082	0.554
CLV_PCSK_KEX2_1	206	208	PF00082	0.687
CLV_PCSK_KEX2_1	23	25	PF00082	0.590
CLV_PCSK_KEX2_1	283	285	PF00082	0.518
CLV_PCSK_PC1ET2_1	143	145	PF00082	0.500
CLV_PCSK_SKI1_1	102	106	PF00082	0.488
CLV_PCSK_SKI1_1	236	240	PF00082	0.569
CLV_PCSK_SKI1_1	308	312	PF00082	0.445
CLV_PCSK_SKI1_1	73	77	PF00082	0.547
CLV_PCSK_SKI1_1	85	89	PF00082	0.478
DEG_APCC_DBOX_1	100	108	PF00400	0.462
DEG_APCC_DBOX_1	307	315	PF00400	0.447
DEG_SPOP_SBC_1	179	183	PF00917	0.678
DEG_SPOP_SBC_1	214	218	PF00917	0.560
DEG_SPOP_SBC_1	51	55	PF00917	0.522
DOC_CKS1_1	1	6	PF01111	0.592
DOC_MAPK_gen_1	101	107	PF00069	0.535
DOC_USP7_MATH_1	12	16	PF00917	0.737
DOC_USP7_MATH_1	179	183	PF00917	0.689
DOC_USP7_MATH_1	189	193	PF00917	0.745
DOC_USP7_MATH_1	25	29	PF00917	0.748
DOC_WW_Pin1_4	13	18	PF00397	0.598
DOC_WW_Pin1_4	165	170	PF00397	0.488
DOC_WW_Pin1_4	181	186	PF00397	0.690
DOC_WW_Pin1_4	32	37	PF00397	0.552
DOC_WW_Pin1_4	57	62	PF00397	0.696
LIG_14-3-3_CanoR_1	23	33	PF00244	0.610
LIG_14-3-3_CanoR_1	283	287	PF00244	0.608
LIG_14-3-3_CanoR_1	90	98	PF00244	0.519
LIG_BIR_II_1	1	5	PF00653	0.608
LIG_BRCT_BRCA1_1	230	234	PF00533	0.464
LIG_BRCT_BRCA1_1	71	75	PF00533	0.542
LIG_BRCT_BRCA1_2	230	236	PF00533	0.601
LIG_CaM_IQ_9	77	92	PF13499	0.415
LIG_LYPXL_yS_3	62	65	PF13949	0.414
LIG_SH2_CRK	242	246	PF00017	0.617
LIG_SH2_STAT5	254	257	PF00017	0.675
LIG_SH3_2	201	206	PF14604	0.477
LIG_SH3_2	39	44	PF14604	0.462
LIG_SH3_3	198	204	PF00018	0.484
LIG_SH3_3	30	36	PF00018	0.523
LIG_SH3_3	37	43	PF00018	0.533
LIG_SH3_3	55	61	PF00018	0.607
LIG_SUMO_SIM_par_1	116	124	PF11976	0.538
LIG_TRAF2_1	138	141	PF00917	0.500
LIG_TRAF2_1	266	269	PF00917	0.526
LIG_TYR_ITIM	240	245	PF00017	0.643
LIG_UBA3_1	104	110	PF00899	0.525
LIG_UBA3_1	310	315	PF00899	0.527
MOD_CDK_SPK_2	165	170	PF00069	0.436
MOD_CK1_1	227	233	PF00069	0.497
MOD_CK1_1	258	264	PF00069	0.705
MOD_CK1_1	8	14	PF00069	0.696
MOD_CK2_1	110	116	PF00069	0.471
MOD_CK2_1	174	180	PF00069	0.697
MOD_GlcNHglycan	133	136	PF01048	0.425
MOD_GlcNHglycan	165	168	PF01048	0.589
MOD_GlcNHglycan	191	194	PF01048	0.606
MOD_GlcNHglycan	196	199	PF01048	0.595
MOD_GlcNHglycan	217	220	PF01048	0.561
MOD_GlcNHglycan	260	263	PF01048	0.641
MOD_GlcNHglycan	27	30	PF01048	0.654
MOD_GlcNHglycan	55	58	PF01048	0.670
MOD_GlcNHglycan	8	11	PF01048	0.649
MOD_GSK3_1	165	172	PF00069	0.595
MOD_GSK3_1	174	181	PF00069	0.639
MOD_GSK3_1	209	216	PF00069	0.497
MOD_GSK3_1	223	230	PF00069	0.441
MOD_GSK3_1	53	60	PF00069	0.647
MOD_GSK3_1	6	13	PF00069	0.643
MOD_N-GLC_1	214	219	PF02516	0.570
MOD_N-GLC_1	5	10	PF02516	0.598
MOD_PIKK_1	110	116	PF00454	0.415
MOD_PKA_2	131	137	PF00069	0.431
MOD_PKA_2	258	264	PF00069	0.690
MOD_PKA_2	282	288	PF00069	0.513
MOD_PKA_2	89	95	PF00069	0.535
MOD_Plk_1	227	233	PF00069	0.522
MOD_Plk_4	209	215	PF00069	0.622
MOD_ProDKin_1	13	19	PF00069	0.596
MOD_ProDKin_1	165	171	PF00069	0.491
MOD_ProDKin_1	181	187	PF00069	0.690
MOD_ProDKin_1	32	38	PF00069	0.552
MOD_ProDKin_1	57	63	PF00069	0.691
MOD_SUMO_rev_2	291	300	PF00179	0.484
MOD_SUMO_rev_2	99	104	PF00179	0.472
TRG_DiLeu_BaEn_1	100	105	PF01217	0.474
TRG_DiLeu_BaEn_1	306	311	PF01217	0.503
TRG_DiLeu_BaLyEn_6	93	98	PF01217	0.529
TRG_ENDOCYTIC_2	242	245	PF00928	0.619
TRG_ENDOCYTIC_2	62	65	PF00928	0.450
TRG_ER_diArg_1	282	284	PF00400	0.557
TRG_NES_CRM1_1	116	131	PF08389	0.539
TRG_Pf-PMV_PEXEL_1	308	312	PF00026	0.479
TRG_Pf-PMV_PEXEL_1	315	319	PF00026	0.545
TRG_Pf-PMV_PEXEL_1	96	100	PF00026	0.532

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PE12	Leptomonas seymouri	57%	100%
A0A0S4IXZ1	Bodo saltans	25%	100%
A0A1X0P0W7	Trypanosomatidae	38%	100%
A0A3R7NUE3	Trypanosoma rangeli	36%	100%
A0A3S7X6M7	Leishmania donovani	88%	97%
A4HLG6	Leishmania braziliensis	64%	95%
A4I8X7	Leishmania infantum	88%	97%
D0A4X5	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	35%	100%
Q4Q478	Leishmania major	86%	100%