LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania mexicana
UniProt:
E9B3T7_LEIMU
TriTrypDb:
LmxM.32.1035
Length:
177

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 4
Forrest at al. (procyclic) no yes: 4
Silverman et al. no yes: 0
Pissara et al. yes yes: 9
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 8
NetGPI no yes: 0, no: 8
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B3T7
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B3T7

Putative motif mimicry

Leishmania From To Domain/Motif Score
DOC_PP4_FxxP_1 143 146 PF00568 0.439
DOC_PP4_FxxP_1 150 153 PF00568 0.435
DOC_USP7_MATH_1 78 82 PF00917 0.831
DOC_WW_Pin1_4 128 133 PF00397 0.513
DOC_WW_Pin1_4 23 28 PF00397 0.759
DOC_WW_Pin1_4 61 66 PF00397 0.637
LIG_BRCT_BRCA1_1 146 150 PF00533 0.449
LIG_FHA_2 85 91 PF00498 0.802
LIG_LIR_Apic_2 139 145 PF02991 0.462
LIG_LIR_Apic_2 147 153 PF02991 0.479
LIG_LIR_Apic_2 156 161 PF02991 0.498
LIG_PDZ_Class_3 172 177 PF00595 0.687
LIG_SH2_STAT5 135 138 PF00017 0.519
LIG_SH2_STAT5 142 145 PF00017 0.408
LIG_SH3_3 115 121 PF00018 0.682
LIG_SH3_3 43 49 PF00018 0.842
LIG_SH3_3 67 73 PF00018 0.643
MOD_CK1_1 20 26 PF00069 0.754
MOD_CK1_1 59 65 PF00069 0.702
MOD_CK1_1 66 72 PF00069 0.701
MOD_CK1_1 81 87 PF00069 0.744
MOD_CK2_1 169 175 PF00069 0.662
MOD_GlcNHglycan 19 22 PF01048 0.693
MOD_GSK3_1 34 41 PF00069 0.859
MOD_GSK3_1 59 66 PF00069 0.684
MOD_N-GLC_1 32 37 PF02516 0.789
MOD_N-GLC_1 66 71 PF02516 0.665
MOD_NEK2_1 1 6 PF00069 0.724
MOD_NMyristoyl 1 7 PF02799 0.629
MOD_PKA_2 17 23 PF00069 0.651
MOD_Plk_1 66 72 PF00069 0.659
MOD_Plk_2-3 169 175 PF00069 0.668
MOD_ProDKin_1 128 134 PF00069 0.503
MOD_ProDKin_1 23 29 PF00069 0.763
MOD_ProDKin_1 61 67 PF00069 0.636
MOD_SPalmitoyl_4 1 7 PF01529 0.629
MOD_SUMO_for_1 126 129 PF00179 0.501
MOD_SUMO_rev_2 79 87 PF00179 0.843

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1I074 Leptomonas seymouri 51% 100%
A0A3R7MVG2 Trypanosoma rangeli 39% 100%
A0A3S7X6J5 Leishmania donovani 76% 100%
A4HLF7 Leishmania braziliensis 56% 83%
A4I8W8 Leishmania infantum 76% 100%
D0A4W3 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 43% 100%
Q4Q487 Leishmania major 71% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS