LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania mexicana
UniProt:
E9B3T0_LEIMU
TriTrypDb:
LmxM.32.0970
Length:
598

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 6
NetGPI no yes: 0, no: 6
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B3T0
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B3T0

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 189 191 PF00675 0.608
CLV_NRD_NRD_1 255 257 PF00675 0.436
CLV_NRD_NRD_1 293 295 PF00675 0.502
CLV_NRD_NRD_1 311 313 PF00675 0.626
CLV_NRD_NRD_1 336 338 PF00675 0.562
CLV_NRD_NRD_1 427 429 PF00675 0.626
CLV_NRD_NRD_1 437 439 PF00675 0.629
CLV_NRD_NRD_1 440 442 PF00675 0.632
CLV_NRD_NRD_1 469 471 PF00675 0.641
CLV_NRD_NRD_1 477 479 PF00675 0.612
CLV_NRD_NRD_1 481 483 PF00675 0.605
CLV_NRD_NRD_1 97 99 PF00675 0.391
CLV_PCSK_FUR_1 438 442 PF00082 0.706
CLV_PCSK_KEX2_1 189 191 PF00082 0.582
CLV_PCSK_KEX2_1 269 271 PF00082 0.434
CLV_PCSK_KEX2_1 293 295 PF00082 0.502
CLV_PCSK_KEX2_1 425 427 PF00082 0.648
CLV_PCSK_KEX2_1 436 438 PF00082 0.693
CLV_PCSK_KEX2_1 440 442 PF00082 0.714
CLV_PCSK_KEX2_1 469 471 PF00082 0.641
CLV_PCSK_KEX2_1 477 479 PF00082 0.612
CLV_PCSK_KEX2_1 481 483 PF00082 0.605
CLV_PCSK_KEX2_1 97 99 PF00082 0.391
CLV_PCSK_PC1ET2_1 269 271 PF00082 0.491
CLV_PCSK_PC1ET2_1 425 427 PF00082 0.744
CLV_PCSK_PC7_1 265 271 PF00082 0.543
CLV_PCSK_PC7_1 289 295 PF00082 0.490
CLV_PCSK_PC7_1 433 439 PF00082 0.679
CLV_PCSK_PC7_1 477 483 PF00082 0.628
CLV_PCSK_SKI1_1 129 133 PF00082 0.635
CLV_PCSK_SKI1_1 289 293 PF00082 0.615
CLV_PCSK_SKI1_1 46 50 PF00082 0.488
CLV_PCSK_SKI1_1 567 571 PF00082 0.484
CLV_PCSK_SKI1_1 84 88 PF00082 0.523
DEG_SIAH_1 506 514 PF03145 0.580
DEG_SPOP_SBC_1 461 465 PF00917 0.679
DEG_SPOP_SBC_1 588 592 PF00917 0.478
DOC_ANK_TNKS_1 480 487 PF00023 0.503
DOC_CKS1_1 49 54 PF01111 0.457
DOC_CYCLIN_RxL_1 43 51 PF00134 0.428
DOC_CYCLIN_RxL_1 81 91 PF00134 0.505
DOC_MAPK_gen_1 269 278 PF00069 0.407
DOC_MAPK_gen_1 97 105 PF00069 0.394
DOC_MAPK_MEF2A_6 97 105 PF00069 0.470
DOC_MAPK_NFAT4_5 98 106 PF00069 0.472
DOC_MAPK_RevD_3 83 98 PF00069 0.422
DOC_PP1_RVXF_1 292 299 PF00149 0.407
DOC_PP2B_LxvP_1 18 21 PF13499 0.369
DOC_USP7_MATH_1 167 171 PF00917 0.662
DOC_USP7_MATH_1 308 312 PF00917 0.721
DOC_USP7_MATH_1 432 436 PF00917 0.598
DOC_USP7_MATH_1 451 455 PF00917 0.614
DOC_USP7_MATH_1 461 465 PF00917 0.629
DOC_USP7_MATH_1 53 57 PF00917 0.585
DOC_USP7_MATH_2 414 420 PF00917 0.560
DOC_USP7_MATH_2 518 524 PF00917 0.514
DOC_USP7_UBL2_3 313 317 PF12436 0.624
DOC_WW_Pin1_4 129 134 PF00397 0.689
DOC_WW_Pin1_4 238 243 PF00397 0.442
DOC_WW_Pin1_4 398 403 PF00397 0.610
DOC_WW_Pin1_4 426 431 PF00397 0.637
DOC_WW_Pin1_4 439 444 PF00397 0.633
DOC_WW_Pin1_4 457 462 PF00397 0.671
DOC_WW_Pin1_4 48 53 PF00397 0.492
DOC_WW_Pin1_4 545 550 PF00397 0.602
LIG_14-3-3_CanoR_1 123 128 PF00244 0.641
LIG_14-3-3_CanoR_1 453 461 PF00244 0.652
LIG_14-3-3_CanoR_1 55 63 PF00244 0.552
LIG_14-3-3_CanoR_1 98 104 PF00244 0.464
LIG_14-3-3_CterR_2 595 598 PF00244 0.540
LIG_Actin_WH2_2 11 27 PF00022 0.312
LIG_BIR_II_1 1 5 PF00653 0.595
LIG_Clathr_ClatBox_1 15 19 PF01394 0.334
LIG_Clathr_ClatBox_1 275 279 PF01394 0.404
LIG_FHA_1 100 106 PF00498 0.476
LIG_FHA_1 11 17 PF00498 0.341
LIG_FHA_1 130 136 PF00498 0.742
LIG_FHA_1 203 209 PF00498 0.418
LIG_FHA_1 352 358 PF00498 0.545
LIG_FHA_1 43 49 PF00498 0.434
LIG_FHA_1 500 506 PF00498 0.520
LIG_FHA_1 546 552 PF00498 0.627
LIG_FHA_2 170 176 PF00498 0.641
LIG_FHA_2 55 61 PF00498 0.482
LIG_FHA_2 584 590 PF00498 0.478
LIG_FHA_2 76 82 PF00498 0.406
LIG_LIR_Apic_2 302 308 PF02991 0.636
LIG_LIR_Apic_2 590 596 PF02991 0.483
LIG_LIR_Nem_3 209 215 PF02991 0.371
LIG_LIR_Nem_3 241 246 PF02991 0.485
LIG_LIR_Nem_3 271 275 PF02991 0.476
LIG_LIR_Nem_3 577 581 PF02991 0.402
LIG_MYND_1 133 137 PF01753 0.677
LIG_PCNA_PIPBox_1 204 213 PF02747 0.399
LIG_PCNA_yPIPBox_3 198 211 PF02747 0.400
LIG_Pex14_1 566 570 PF04695 0.413
LIG_PTB_Apo_2 328 335 PF02174 0.378
LIG_PTB_Phospho_1 328 334 PF10480 0.370
LIG_Rb_pABgroove_1 29 37 PF01858 0.412
LIG_SH2_CRK 246 250 PF00017 0.467
LIG_SH2_GRB2like 329 332 PF00017 0.366
LIG_SH2_SRC 5 8 PF00017 0.452
LIG_SH2_STAP1 5 9 PF00017 0.402
LIG_SH2_STAT5 100 103 PF00017 0.386
LIG_SH2_STAT5 329 332 PF00017 0.394
LIG_SH3_3 160 166 PF00018 0.594
LIG_SH3_3 174 180 PF00018 0.657
LIG_SH3_3 236 242 PF00018 0.446
LIG_SH3_3 24 30 PF00018 0.315
LIG_SH3_3 375 381 PF00018 0.581
LIG_SH3_3 546 552 PF00018 0.620
LIG_SH3_4 313 320 PF00018 0.593
LIG_SUMO_SIM_anti_2 13 19 PF11976 0.335
LIG_SUMO_SIM_par_1 13 19 PF11976 0.335
LIG_SUMO_SIM_par_1 204 209 PF11976 0.401
LIG_SUMO_SIM_par_1 257 262 PF11976 0.416
LIG_SUMO_SIM_par_1 274 279 PF11976 0.399
LIG_TRFH_1 238 242 PF08558 0.407
LIG_ULM_U2AF65_1 469 474 PF00076 0.504
LIG_WRC_WIRS_1 207 212 PF05994 0.441
MOD_CDC14_SPxK_1 401 404 PF00782 0.611
MOD_CDK_SPK_2 428 433 PF00069 0.624
MOD_CDK_SPxK_1 398 404 PF00069 0.613
MOD_CDK_SPxxK_3 426 433 PF00069 0.597
MOD_CDK_SPxxK_3 48 55 PF00069 0.462
MOD_CK1_1 149 155 PF00069 0.682
MOD_CK1_1 439 445 PF00069 0.801
MOD_CK1_1 452 458 PF00069 0.559
MOD_CK1_1 460 466 PF00069 0.621
MOD_CK1_1 538 544 PF00069 0.580
MOD_CK2_1 147 153 PF00069 0.509
MOD_CK2_1 169 175 PF00069 0.639
MOD_CK2_1 185 191 PF00069 0.557
MOD_CK2_1 392 398 PF00069 0.593
MOD_CK2_1 54 60 PF00069 0.473
MOD_CK2_1 583 589 PF00069 0.470
MOD_Cter_Amidation 475 478 PF01082 0.640
MOD_DYRK1A_RPxSP_1 129 133 PF00069 0.508
MOD_DYRK1A_RPxSP_1 428 432 PF00069 0.558
MOD_DYRK1A_RPxSP_1 457 461 PF00069 0.637
MOD_GlcNHglycan 153 156 PF01048 0.693
MOD_GlcNHglycan 169 172 PF01048 0.684
MOD_GlcNHglycan 418 421 PF01048 0.650
MOD_GlcNHglycan 449 452 PF01048 0.786
MOD_GlcNHglycan 543 546 PF01048 0.707
MOD_GlcNHglycan 57 60 PF01048 0.472
MOD_GSK3_1 145 152 PF00069 0.557
MOD_GSK3_1 167 174 PF00069 0.660
MOD_GSK3_1 185 192 PF00069 0.672
MOD_GSK3_1 202 209 PF00069 0.438
MOD_GSK3_1 234 241 PF00069 0.604
MOD_GSK3_1 392 399 PF00069 0.601
MOD_GSK3_1 428 435 PF00069 0.676
MOD_GSK3_1 439 446 PF00069 0.791
MOD_GSK3_1 447 454 PF00069 0.773
MOD_GSK3_1 457 464 PF00069 0.645
MOD_GSK3_1 525 532 PF00069 0.641
MOD_GSK3_1 541 548 PF00069 0.644
MOD_GSK3_1 583 590 PF00069 0.471
MOD_N-GLC_1 10 15 PF02516 0.271
MOD_N-GLC_1 330 335 PF02516 0.361
MOD_N-GLC_1 345 350 PF02516 0.529
MOD_NEK2_1 10 15 PF00069 0.355
MOD_NEK2_1 151 156 PF00069 0.604
MOD_NEK2_1 185 190 PF00069 0.586
MOD_NEK2_1 34 39 PF00069 0.403
MOD_NEK2_1 69 74 PF00069 0.380
MOD_NEK2_2 332 337 PF00069 0.528
MOD_PIKK_1 529 535 PF00454 0.741
MOD_PIKK_1 568 574 PF00454 0.499
MOD_PK_1 123 129 PF00069 0.607
MOD_PK_1 161 167 PF00069 0.560
MOD_PK_1 392 398 PF00069 0.626
MOD_PKA_1 189 195 PF00069 0.501
MOD_PKA_1 436 442 PF00069 0.629
MOD_PKA_2 185 191 PF00069 0.552
MOD_PKA_2 396 402 PF00069 0.695
MOD_PKA_2 432 438 PF00069 0.689
MOD_PKA_2 452 458 PF00069 0.662
MOD_PKA_2 54 60 PF00069 0.564
MOD_PKB_1 121 129 PF00069 0.634
MOD_PKB_1 447 455 PF00069 0.684
MOD_Plk_1 330 336 PF00069 0.358
MOD_Plk_1 588 594 PF00069 0.485
MOD_Plk_2-3 589 595 PF00069 0.486
MOD_Plk_4 202 208 PF00069 0.448
MOD_Plk_4 574 580 PF00069 0.415
MOD_ProDKin_1 129 135 PF00069 0.688
MOD_ProDKin_1 238 244 PF00069 0.434
MOD_ProDKin_1 398 404 PF00069 0.613
MOD_ProDKin_1 426 432 PF00069 0.632
MOD_ProDKin_1 439 445 PF00069 0.635
MOD_ProDKin_1 457 463 PF00069 0.669
MOD_ProDKin_1 48 54 PF00069 0.493
MOD_ProDKin_1 545 551 PF00069 0.602
MOD_SUMO_for_1 268 271 PF00179 0.516
MOD_SUMO_rev_2 144 149 PF00179 0.562
TRG_DiLeu_BaEn_1 271 276 PF01217 0.472
TRG_ENDOCYTIC_2 100 103 PF00928 0.386
TRG_ENDOCYTIC_2 246 249 PF00928 0.459
TRG_ER_diArg_1 121 124 PF00400 0.540
TRG_ER_diArg_1 426 428 PF00400 0.632
TRG_ER_diArg_1 436 438 PF00400 0.634
TRG_ER_diArg_1 469 471 PF00400 0.633
TRG_ER_diArg_1 477 479 PF00400 0.623
TRG_ER_diArg_1 82 85 PF00400 0.495
TRG_ER_diArg_1 96 98 PF00400 0.362
TRG_NLS_MonoCore_2 424 429 PF00514 0.704
TRG_NLS_MonoExtN_4 423 429 PF00514 0.649
TRG_Pf-PMV_PEXEL_1 273 277 PF00026 0.407

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1ILA8 Leptomonas seymouri 51% 100%
A0A3S7X6I2 Leishmania donovani 87% 100%
A4HLF2 Leishmania braziliensis 71% 98%
A4I8W1 Leishmania infantum 87% 100%
Q4Q494 Leishmania major 82% 100%

Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS