Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania mexicana

UniProt:

E9B3R7_LEIMU

TriTrypDb:

LmxM.32.0850

Length:

928

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B3R7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B3R7

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	405	409	PF00656	0.794
CLV_C14_Caspase3-7	585	589	PF00656	0.741
CLV_NRD_NRD_1	11	13	PF00675	0.643
CLV_NRD_NRD_1	160	162	PF00675	0.753
CLV_NRD_NRD_1	171	173	PF00675	0.629
CLV_NRD_NRD_1	322	324	PF00675	0.525
CLV_NRD_NRD_1	410	412	PF00675	0.673
CLV_NRD_NRD_1	442	444	PF00675	0.737
CLV_NRD_NRD_1	466	468	PF00675	0.598
CLV_NRD_NRD_1	786	788	PF00675	0.769
CLV_NRD_NRD_1	795	797	PF00675	0.657
CLV_NRD_NRD_1	844	846	PF00675	0.644
CLV_PCSK_KEX2_1	11	13	PF00082	0.643
CLV_PCSK_KEX2_1	160	162	PF00082	0.702
CLV_PCSK_KEX2_1	171	173	PF00082	0.581
CLV_PCSK_KEX2_1	322	324	PF00082	0.522
CLV_PCSK_KEX2_1	441	443	PF00082	0.738
CLV_PCSK_KEX2_1	795	797	PF00082	0.698
CLV_PCSK_KEX2_1	844	846	PF00082	0.644
CLV_PCSK_SKI1_1	426	430	PF00082	0.539
CLV_PCSK_SKI1_1	821	825	PF00082	0.720
CLV_PCSK_SKI1_1	832	836	PF00082	0.708
CLV_PCSK_SKI1_1	848	852	PF00082	0.518
CLV_PCSK_SKI1_1	876	880	PF00082	0.518
DEG_APCC_DBOX_1	820	828	PF00400	0.716
DEG_Kelch_Keap1_1	560	565	PF01344	0.549
DEG_Nend_Nbox_1	1	3	PF02207	0.696
DEG_SCF_FBW7_1	482	489	PF00400	0.740
DEG_SCF_FBW7_1	909	915	PF00400	0.751
DEG_SPOP_SBC_1	558	562	PF00917	0.703
DOC_CDC14_PxL_1	153	161	PF14671	0.706
DOC_CKS1_1	500	505	PF01111	0.521
DOC_CKS1_1	836	841	PF01111	0.765
DOC_CKS1_1	909	914	PF01111	0.654
DOC_CYCLIN_yCln2_LP_2	707	713	PF00134	0.733
DOC_CYCLIN_yCln2_LP_2	836	842	PF00134	0.720
DOC_MAPK_DCC_7	701	709	PF00069	0.670
DOC_MAPK_gen_1	319	329	PF00069	0.510
DOC_MAPK_gen_1	441	450	PF00069	0.575
DOC_MAPK_HePTP_8	215	227	PF00069	0.508
DOC_MAPK_MEF2A_6	146	153	PF00069	0.512
DOC_MAPK_MEF2A_6	218	227	PF00069	0.514
DOC_MAPK_MEF2A_6	701	709	PF00069	0.670
DOC_PP1_RVXF_1	251	258	PF00149	0.500
DOC_PP2B_LxvP_1	227	230	PF13499	0.462
DOC_PP2B_LxvP_1	707	710	PF13499	0.744
DOC_PP2B_LxvP_1	907	910	PF13499	0.667
DOC_PP4_FxxP_1	177	180	PF00568	0.688
DOC_PP4_FxxP_1	257	260	PF00568	0.492
DOC_PP4_FxxP_1	733	736	PF00568	0.676
DOC_USP7_MATH_1	109	113	PF00917	0.614
DOC_USP7_MATH_1	173	177	PF00917	0.709
DOC_USP7_MATH_1	270	274	PF00917	0.677
DOC_USP7_MATH_1	3	7	PF00917	0.668
DOC_USP7_MATH_1	399	403	PF00917	0.765
DOC_USP7_MATH_1	449	453	PF00917	0.667
DOC_USP7_MATH_1	486	490	PF00917	0.704
DOC_USP7_MATH_1	521	525	PF00917	0.487
DOC_USP7_MATH_1	559	563	PF00917	0.662
DOC_USP7_MATH_1	714	718	PF00917	0.749
DOC_USP7_MATH_1	808	812	PF00917	0.663
DOC_USP7_MATH_1	895	899	PF00917	0.480
DOC_WW_Pin1_4	130	135	PF00397	0.717
DOC_WW_Pin1_4	382	387	PF00397	0.753
DOC_WW_Pin1_4	471	476	PF00397	0.716
DOC_WW_Pin1_4	482	487	PF00397	0.767
DOC_WW_Pin1_4	489	494	PF00397	0.627
DOC_WW_Pin1_4	499	504	PF00397	0.564
DOC_WW_Pin1_4	554	559	PF00397	0.752
DOC_WW_Pin1_4	614	619	PF00397	0.741
DOC_WW_Pin1_4	804	809	PF00397	0.696
DOC_WW_Pin1_4	835	840	PF00397	0.771
DOC_WW_Pin1_4	887	892	PF00397	0.662
DOC_WW_Pin1_4	898	903	PF00397	0.631
DOC_WW_Pin1_4	908	913	PF00397	0.594
LIG_14-3-3_CanoR_1	14	19	PF00244	0.579
LIG_14-3-3_CanoR_1	172	178	PF00244	0.635
LIG_14-3-3_CanoR_1	232	240	PF00244	0.455
LIG_14-3-3_CanoR_1	253	258	PF00244	0.500
LIG_14-3-3_CanoR_1	426	431	PF00244	0.740
LIG_14-3-3_CanoR_1	467	475	PF00244	0.571
LIG_14-3-3_CanoR_1	57	65	PF00244	0.694
LIG_14-3-3_CanoR_1	611	618	PF00244	0.681
LIG_14-3-3_CanoR_1	661	665	PF00244	0.437
LIG_14-3-3_CanoR_1	795	801	PF00244	0.521
LIG_14-3-3_CterR_2	924	928	PF00244	0.580
LIG_Actin_WH2_2	712	730	PF00022	0.742
LIG_APCC_ABBA_1	145	150	PF00400	0.503
LIG_APCC_ABBA_1	825	830	PF00400	0.691
LIG_BIR_III_4	629	633	PF00653	0.512
LIG_BRCT_BRCA1_1	235	239	PF00533	0.449
LIG_BRCT_BRCA1_1	253	257	PF00533	0.501
LIG_BRCT_BRCA1_1	846	850	PF00533	0.756
LIG_CSL_BTD_1	750	753	PF09270	0.662
LIG_deltaCOP1_diTrp_1	250	257	PF00928	0.599
LIG_FHA_1	229	235	PF00498	0.464
LIG_FHA_1	260	266	PF00498	0.654
LIG_FHA_1	28	34	PF00498	0.541
LIG_FHA_1	427	433	PF00498	0.522
LIG_FHA_1	877	883	PF00498	0.464
LIG_FHA_1	909	915	PF00498	0.649
LIG_FHA_2	131	137	PF00498	0.625
LIG_FHA_2	22	28	PF00498	0.690
LIG_FHA_2	403	409	PF00498	0.843
LIG_FHA_2	500	506	PF00498	0.580
LIG_FHA_2	541	547	PF00498	0.718
LIG_FHA_2	561	567	PF00498	0.595
LIG_LIR_Apic_2	176	180	PF02991	0.695
LIG_LIR_Apic_2	254	260	PF02991	0.489
LIG_LIR_Apic_2	663	669	PF02991	0.558
LIG_LIR_Gen_1	100	110	PF02991	0.565
LIG_LIR_Gen_1	292	301	PF02991	0.526
LIG_LIR_Gen_1	647	656	PF02991	0.473
LIG_LIR_Nem_3	100	106	PF02991	0.661
LIG_LIR_Nem_3	250	255	PF02991	0.506
LIG_LIR_Nem_3	292	298	PF02991	0.543
LIG_LIR_Nem_3	303	308	PF02991	0.508
LIG_LIR_Nem_3	643	648	PF02991	0.529
LIG_LIR_Nem_3	920	926	PF02991	0.627
LIG_NRBOX	242	248	PF00104	0.466
LIG_NRBOX	578	584	PF00104	0.623
LIG_Pex14_1	679	683	PF04695	0.570
LIG_Pex14_2	645	649	PF04695	0.534
LIG_SH2_CRK	712	716	PF00017	0.744
LIG_SH2_STAP1	266	270	PF00017	0.733
LIG_SH2_STAP1	333	337	PF00017	0.559
LIG_SH2_STAT3	113	116	PF00017	0.588
LIG_SH2_STAT3	684	687	PF00017	0.514
LIG_SH2_STAT5	113	116	PF00017	0.564
LIG_SH2_STAT5	367	370	PF00017	0.698
LIG_SH2_STAT5	609	612	PF00017	0.712
LIG_SH3_1	383	389	PF00018	0.704
LIG_SH3_3	103	109	PF00018	0.683
LIG_SH3_3	131	137	PF00018	0.722
LIG_SH3_3	383	389	PF00018	0.725
LIG_SH3_3	78	84	PF00018	0.640
LIG_SH3_3	906	912	PF00018	0.660
LIG_SUMO_SIM_anti_2	347	355	PF11976	0.660
LIG_TRAF2_1	359	362	PF00917	0.749
LIG_TRAF2_1	377	380	PF00917	0.482
LIG_TRAF2_1	543	546	PF00917	0.728
LIG_TRAF2_1	881	884	PF00917	0.753
LIG_TRAF2_1	915	918	PF00917	0.662
LIG_TRAF2_2	389	394	PF00917	0.739
LIG_TRFH_1	835	839	PF08558	0.674
LIG_WRC_WIRS_1	343	348	PF05994	0.551
LIG_WW_3	168	172	PF00397	0.603
MOD_CDK_SPxxK_3	614	621	PF00069	0.744
MOD_CK1_1	130	136	PF00069	0.629
MOD_CK1_1	251	257	PF00069	0.525
MOD_CK1_1	281	287	PF00069	0.761
MOD_CK1_1	304	310	PF00069	0.378
MOD_CK1_1	402	408	PF00069	0.717
MOD_CK1_1	471	477	PF00069	0.769
MOD_CK1_1	489	495	PF00069	0.711
MOD_CK1_1	499	505	PF00069	0.679
MOD_CK1_1	552	558	PF00069	0.833
MOD_CK1_1	560	566	PF00069	0.623
MOD_CK1_1	614	620	PF00069	0.791
MOD_CK1_1	798	804	PF00069	0.665
MOD_CK1_1	806	812	PF00069	0.623
MOD_CK1_1	898	904	PF00069	0.545
MOD_CK1_1	97	103	PF00069	0.580
MOD_CK2_1	130	136	PF00069	0.630
MOD_CK2_1	21	27	PF00069	0.691
MOD_CK2_1	374	380	PF00069	0.757
MOD_CK2_1	471	477	PF00069	0.683
MOD_CK2_1	540	546	PF00069	0.711
MOD_CK2_1	559	565	PF00069	0.730
MOD_CK2_1	796	802	PF00069	0.814
MOD_CK2_1	806	812	PF00069	0.740
MOD_CK2_1	912	918	PF00069	0.668
MOD_DYRK1A_RPxSP_1	887	891	PF00069	0.662
MOD_GlcNHglycan	117	120	PF01048	0.700
MOD_GlcNHglycan	129	132	PF01048	0.617
MOD_GlcNHglycan	268	271	PF01048	0.677
MOD_GlcNHglycan	280	283	PF01048	0.786
MOD_GlcNHglycan	376	379	PF01048	0.745
MOD_GlcNHglycan	40	43	PF01048	0.698
MOD_GlcNHglycan	401	404	PF01048	0.655
MOD_GlcNHglycan	444	448	PF01048	0.720
MOD_GlcNHglycan	470	473	PF01048	0.796
MOD_GlcNHglycan	5	8	PF01048	0.690
MOD_GlcNHglycan	551	554	PF01048	0.840
MOD_GlcNHglycan	565	571	PF01048	0.583
MOD_GlcNHglycan	59	62	PF01048	0.698
MOD_GlcNHglycan	642	645	PF01048	0.587
MOD_GlcNHglycan	716	719	PF01048	0.750
MOD_GlcNHglycan	74	77	PF01048	0.552
MOD_GlcNHglycan	96	99	PF01048	0.692
MOD_GSK3_1	160	167	PF00069	0.713
MOD_GSK3_1	21	28	PF00069	0.658
MOD_GSK3_1	266	273	PF00069	0.757
MOD_GSK3_1	300	307	PF00069	0.558
MOD_GSK3_1	342	349	PF00069	0.580
MOD_GSK3_1	370	377	PF00069	0.718
MOD_GSK3_1	398	405	PF00069	0.807
MOD_GSK3_1	426	433	PF00069	0.688
MOD_GSK3_1	473	480	PF00069	0.686
MOD_GSK3_1	482	489	PF00069	0.656
MOD_GSK3_1	545	552	PF00069	0.748
MOD_GSK3_1	554	561	PF00069	0.711
MOD_GSK3_1	587	594	PF00069	0.682
MOD_GSK3_1	607	614	PF00069	0.535
MOD_GSK3_1	660	667	PF00069	0.521
MOD_GSK3_1	68	75	PF00069	0.782
MOD_GSK3_1	693	700	PF00069	0.569
MOD_GSK3_1	743	750	PF00069	0.688
MOD_GSK3_1	804	811	PF00069	0.774
MOD_GSK3_1	844	851	PF00069	0.479
MOD_GSK3_1	908	915	PF00069	0.683
MOD_GSK3_1	94	101	PF00069	0.618
MOD_N-GLC_1	874	879	PF02516	0.633
MOD_NEK2_1	127	132	PF00069	0.586
MOD_NEK2_1	13	18	PF00069	0.594
MOD_NEK2_1	233	238	PF00069	0.455
MOD_NEK2_1	301	306	PF00069	0.406
MOD_NEK2_1	314	319	PF00069	0.596
MOD_NEK2_1	32	37	PF00069	0.593
MOD_NEK2_1	346	351	PF00069	0.530
MOD_NEK2_1	59	64	PF00069	0.768
MOD_NEK2_1	635	640	PF00069	0.475
MOD_NEK2_1	664	669	PF00069	0.592
MOD_NEK2_1	760	765	PF00069	0.661
MOD_NEK2_1	79	84	PF00069	0.534
MOD_NEK2_1	803	808	PF00069	0.647
MOD_NEK2_1	867	872	PF00069	0.758
MOD_NEK2_1	919	924	PF00069	0.632
MOD_PIKK_1	21	27	PF00454	0.691
MOD_PIKK_1	233	239	PF00454	0.453
MOD_PIKK_1	59	65	PF00454	0.766
MOD_PIKK_1	611	617	PF00454	0.781
MOD_PIKK_1	683	689	PF00454	0.715
MOD_PIKK_1	876	882	PF00454	0.576
MOD_PK_1	14	20	PF00069	0.572
MOD_PK_1	796	802	PF00069	0.814
MOD_PKA_1	160	166	PF00069	0.760
MOD_PKA_1	795	801	PF00069	0.521
MOD_PKA_1	844	850	PF00069	0.641
MOD_PKA_2	13	19	PF00069	0.610
MOD_PKA_2	160	166	PF00069	0.713
MOD_PKA_2	248	254	PF00069	0.420
MOD_PKA_2	392	398	PF00069	0.788
MOD_PKA_2	607	613	PF00069	0.743
MOD_PKA_2	660	666	PF00069	0.438
MOD_PKA_2	795	801	PF00069	0.521
MOD_PKA_2	844	850	PF00069	0.641
MOD_PKB_1	12	20	PF00069	0.573
MOD_PKB_1	441	449	PF00069	0.825
MOD_Plk_1	149	155	PF00069	0.537
MOD_Plk_1	270	276	PF00069	0.486
MOD_Plk_1	346	352	PF00069	0.535
MOD_Plk_1	443	449	PF00069	0.567
MOD_Plk_1	494	500	PF00069	0.824
MOD_Plk_1	511	517	PF00069	0.579
MOD_Plk_1	774	780	PF00069	0.681
MOD_Plk_1	867	873	PF00069	0.681
MOD_Plk_1	874	880	PF00069	0.554
MOD_Plk_1	882	888	PF00069	0.460
MOD_Plk_1	919	925	PF00069	0.657
MOD_Plk_4	109	115	PF00069	0.591
MOD_Plk_4	173	179	PF00069	0.738
MOD_Plk_4	28	34	PF00069	0.689
MOD_Plk_4	346	352	PF00069	0.535
MOD_Plk_4	511	517	PF00069	0.771
MOD_Plk_4	660	666	PF00069	0.567
MOD_Plk_4	747	753	PF00069	0.662
MOD_Plk_4	762	768	PF00069	0.646
MOD_ProDKin_1	130	136	PF00069	0.716
MOD_ProDKin_1	382	388	PF00069	0.753
MOD_ProDKin_1	471	477	PF00069	0.718
MOD_ProDKin_1	482	488	PF00069	0.765
MOD_ProDKin_1	489	495	PF00069	0.629
MOD_ProDKin_1	499	505	PF00069	0.560
MOD_ProDKin_1	554	560	PF00069	0.755
MOD_ProDKin_1	614	620	PF00069	0.742
MOD_ProDKin_1	804	810	PF00069	0.697
MOD_ProDKin_1	835	841	PF00069	0.769
MOD_ProDKin_1	887	893	PF00069	0.664
MOD_ProDKin_1	898	904	PF00069	0.632
MOD_ProDKin_1	908	914	PF00069	0.586
MOD_SUMO_for_1	572	575	PF00179	0.749
TRG_DiLeu_BaEn_1	722	727	PF01217	0.629
TRG_DiLeu_BaEn_1	775	780	PF01217	0.755
TRG_DiLeu_BaEn_4	743	749	PF01217	0.677
TRG_DiLeu_BaLyEn_6	215	220	PF01217	0.495
TRG_DiLeu_BaLyEn_6	229	234	PF01217	0.467
TRG_DiLeu_BaLyEn_6	528	533	PF01217	0.630
TRG_DiLeu_BaLyEn_6	578	583	PF01217	0.431
TRG_DiLeu_LyEn_5	722	727	PF01217	0.629
TRG_DiLeu_LyEn_5	734	739	PF01217	0.682
TRG_DiLeu_LyEn_5	775	780	PF01217	0.755
TRG_ENDOCYTIC_2	103	106	PF00928	0.636
TRG_ENDOCYTIC_2	712	715	PF00928	0.694
TRG_ER_diArg_1	10	12	PF00400	0.689
TRG_ER_diArg_1	159	161	PF00400	0.699
TRG_ER_diArg_1	170	172	PF00400	0.664
TRG_ER_diArg_1	321	323	PF00400	0.532
TRG_ER_diArg_1	44	47	PF00400	0.674
TRG_ER_diArg_1	440	443	PF00400	0.766
TRG_ER_diArg_1	464	467	PF00400	0.573
TRG_ER_diArg_1	523	526	PF00400	0.716
TRG_ER_diArg_1	529	532	PF00400	0.691
TRG_ER_diArg_1	776	779	PF00400	0.659
TRG_NES_CRM1_1	238	250	PF08389	0.568
TRG_Pf-PMV_PEXEL_1	218	222	PF00026	0.549
TRG_Pf-PMV_PEXEL_1	232	237	PF00026	0.551
TRG_Pf-PMV_PEXEL_1	316	320	PF00026	0.653
TRG_Pf-PMV_PEXEL_1	508	512	PF00026	0.660
TRG_Pf-PMV_PEXEL_1	581	585	PF00026	0.734
TRG_Pf-PMV_PEXEL_1	725	729	PF00026	0.633
TRG_Pf-PMV_PEXEL_1	778	782	PF00026	0.642

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IH80	Leptomonas seymouri	40%	94%
A0A3S7X6H4	Leishmania donovani	84%	100%
A4HLD9	Leishmania braziliensis	67%	100%
A4I8U8	Leishmania infantum	84%	100%
Q4Q4A7	Leishmania major	85%	100%