Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9B3Q9_LEIMU

TriTrypDb:

LmxM.32.0765

Length:

420

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B3Q9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B3Q9

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	284	288	PF00656	0.603
CLV_C14_Caspase3-7	378	382	PF00656	0.530
CLV_NRD_NRD_1	233	235	PF00675	0.626
CLV_NRD_NRD_1	291	293	PF00675	0.632
CLV_NRD_NRD_1	316	318	PF00675	0.696
CLV_NRD_NRD_1	371	373	PF00675	0.607
CLV_NRD_NRD_1	66	68	PF00675	0.759
CLV_PCSK_KEX2_1	233	235	PF00082	0.626
CLV_PCSK_KEX2_1	290	292	PF00082	0.614
CLV_PCSK_KEX2_1	316	318	PF00082	0.620
CLV_PCSK_KEX2_1	65	67	PF00082	0.760
CLV_PCSK_SKI1_1	332	336	PF00082	0.511
DEG_Nend_Nbox_1	1	3	PF02207	0.611
DEG_SCF_FBW7_1	210	216	PF00400	0.726
DEG_SPOP_SBC_1	44	48	PF00917	0.671
DOC_CKS1_1	210	215	PF01111	0.713
DOC_CKS1_1	218	223	PF01111	0.628
DOC_CKS1_1	226	231	PF01111	0.546
DOC_CKS1_1	272	277	PF01111	0.594
DOC_PP4_FxxP_1	2	5	PF00568	0.711
DOC_PP4_FxxP_1	38	41	PF00568	0.685
DOC_USP7_MATH_1	116	120	PF00917	0.626
DOC_USP7_MATH_1	145	149	PF00917	0.696
DOC_USP7_MATH_1	193	197	PF00917	0.783
DOC_USP7_MATH_1	211	215	PF00917	0.538
DOC_USP7_MATH_1	252	256	PF00917	0.543
DOC_USP7_MATH_1	315	319	PF00917	0.777
DOC_USP7_MATH_1	320	324	PF00917	0.699
DOC_USP7_MATH_1	359	363	PF00917	0.493
DOC_USP7_MATH_1	393	397	PF00917	0.651
DOC_USP7_MATH_1	408	412	PF00917	0.692
DOC_USP7_MATH_1	68	72	PF00917	0.691
DOC_USP7_MATH_1	98	102	PF00917	0.648
DOC_WW_Pin1_4	100	105	PF00397	0.773
DOC_WW_Pin1_4	109	114	PF00397	0.650
DOC_WW_Pin1_4	167	172	PF00397	0.771
DOC_WW_Pin1_4	184	189	PF00397	0.535
DOC_WW_Pin1_4	203	208	PF00397	0.682
DOC_WW_Pin1_4	209	214	PF00397	0.636
DOC_WW_Pin1_4	217	222	PF00397	0.615
DOC_WW_Pin1_4	225	230	PF00397	0.660
DOC_WW_Pin1_4	25	30	PF00397	0.733
DOC_WW_Pin1_4	271	276	PF00397	0.599
DOC_WW_Pin1_4	391	396	PF00397	0.615
LIG_14-3-3_CanoR_1	134	142	PF00244	0.552
LIG_14-3-3_CanoR_1	254	260	PF00244	0.636
LIG_14-3-3_CanoR_1	316	320	PF00244	0.646
LIG_14-3-3_CanoR_1	322	326	PF00244	0.640
LIG_14-3-3_CanoR_1	54	59	PF00244	0.581
LIG_14-3-3_CanoR_1	65	74	PF00244	0.681
LIG_FHA_1	1	7	PF00498	0.663
LIG_FHA_2	256	262	PF00498	0.652
LIG_FHA_2	376	382	PF00498	0.610
LIG_LIR_Apic_2	212	218	PF02991	0.637
LIG_LIR_Apic_2	35	41	PF02991	0.686
LIG_LIR_Gen_1	236	245	PF02991	0.642
LIG_LIR_Gen_1	337	343	PF02991	0.352
LIG_LIR_Nem_3	236	240	PF02991	0.731
LIG_LIR_Nem_3	303	309	PF02991	0.666
LIG_LIR_Nem_3	337	342	PF02991	0.379
LIG_LIR_Nem_3	88	94	PF02991	0.587
LIG_LYPXL_yS_3	91	94	PF13949	0.597
LIG_Pex14_2	335	339	PF04695	0.365
LIG_SH2_STAT5	280	283	PF00017	0.599
LIG_SH3_3	207	213	PF00018	0.678
LIG_SH3_3	215	221	PF00018	0.658
LIG_SH3_3	269	275	PF00018	0.609
LIG_SH3_3	38	44	PF00018	0.691
LIG_SUMO_SIM_par_1	77	83	PF11976	0.684
LIG_TRAF2_1	198	201	PF00917	0.713
LIG_TYR_ITIM	89	94	PF00017	0.589
MOD_CDK_SPK_2	217	222	PF00069	0.625
MOD_CK1_1	103	109	PF00069	0.693
MOD_CK1_1	111	117	PF00069	0.635
MOD_CK1_1	130	136	PF00069	0.548
MOD_CK1_1	137	143	PF00069	0.632
MOD_CK1_1	157	163	PF00069	0.602
MOD_CK1_1	167	173	PF00069	0.729
MOD_CK1_1	17	23	PF00069	0.781
MOD_CK1_1	181	187	PF00069	0.581
MOD_CK1_1	216	222	PF00069	0.668
MOD_CK1_1	255	261	PF00069	0.728
MOD_CK1_1	299	305	PF00069	0.642
MOD_CK1_1	389	395	PF00069	0.577
MOD_CK1_1	403	409	PF00069	0.641
MOD_CK1_1	57	63	PF00069	0.684
MOD_CK1_1	80	86	PF00069	0.644
MOD_CK2_1	21	27	PF00069	0.706
MOD_CK2_1	255	261	PF00069	0.756
MOD_CK2_1	270	276	PF00069	0.537
MOD_CK2_1	30	36	PF00069	0.608
MOD_CK2_1	315	321	PF00069	0.818
MOD_Cter_Amidation	231	234	PF01082	0.632
MOD_Cter_Amidation	63	66	PF01082	0.690
MOD_GlcNHglycan	107	110	PF01048	0.777
MOD_GlcNHglycan	147	150	PF01048	0.746
MOD_GlcNHglycan	156	159	PF01048	0.603
MOD_GlcNHglycan	16	19	PF01048	0.682
MOD_GlcNHglycan	180	183	PF01048	0.690
MOD_GlcNHglycan	230	233	PF01048	0.685
MOD_GlcNHglycan	248	251	PF01048	0.548
MOD_GlcNHglycan	283	286	PF01048	0.737
MOD_GlcNHglycan	293	297	PF01048	0.684
MOD_GlcNHglycan	302	305	PF01048	0.580
MOD_GlcNHglycan	344	349	PF01048	0.614
MOD_GlcNHglycan	388	391	PF01048	0.558
MOD_GlcNHglycan	405	408	PF01048	0.713
MOD_GlcNHglycan	59	62	PF01048	0.661
MOD_GSK3_1	105	112	PF00069	0.685
MOD_GSK3_1	126	133	PF00069	0.759
MOD_GSK3_1	17	24	PF00069	0.710
MOD_GSK3_1	178	185	PF00069	0.611
MOD_GSK3_1	199	206	PF00069	0.663
MOD_GSK3_1	209	216	PF00069	0.703
MOD_GSK3_1	292	299	PF00069	0.689
MOD_GSK3_1	389	396	PF00069	0.641
MOD_GSK3_1	409	416	PF00069	0.482
MOD_N-GLC_1	299	304	PF02516	0.644
MOD_NEK2_1	270	275	PF00069	0.663
MOD_NEK2_1	281	286	PF00069	0.551
MOD_NEK2_1	298	303	PF00069	0.639
MOD_NEK2_1	360	365	PF00069	0.483
MOD_PIKK_1	200	206	PF00454	0.609
MOD_PIKK_1	252	258	PF00454	0.710
MOD_PIKK_1	321	327	PF00454	0.523
MOD_PK_1	127	133	PF00069	0.686
MOD_PKA_1	291	297	PF00069	0.741
MOD_PKA_1	66	72	PF00069	0.693
MOD_PKA_2	126	132	PF00069	0.608
MOD_PKA_2	133	139	PF00069	0.538
MOD_PKA_2	164	170	PF00069	0.623
MOD_PKA_2	291	297	PF00069	0.703
MOD_PKA_2	315	321	PF00069	0.780
MOD_PKA_2	386	392	PF00069	0.632
MOD_PKA_2	398	404	PF00069	0.642
MOD_PKA_2	408	414	PF00069	0.636
MOD_PKA_2	66	72	PF00069	0.635
MOD_PKB_1	176	184	PF00069	0.652
MOD_PKB_1	290	298	PF00069	0.742
MOD_PKB_1	65	73	PF00069	0.692
MOD_Plk_1	235	241	PF00069	0.509
MOD_Plk_4	137	143	PF00069	0.700
MOD_ProDKin_1	100	106	PF00069	0.773
MOD_ProDKin_1	109	115	PF00069	0.647
MOD_ProDKin_1	167	173	PF00069	0.771
MOD_ProDKin_1	184	190	PF00069	0.535
MOD_ProDKin_1	203	209	PF00069	0.683
MOD_ProDKin_1	217	223	PF00069	0.617
MOD_ProDKin_1	225	231	PF00069	0.738
MOD_ProDKin_1	25	31	PF00069	0.732
MOD_ProDKin_1	271	277	PF00069	0.597
MOD_ProDKin_1	391	397	PF00069	0.615
MOD_SUMO_rev_2	147	157	PF00179	0.510
TRG_ENDOCYTIC_2	91	94	PF00928	0.597
TRG_ER_diArg_1	290	292	PF00400	0.700
TRG_ER_diArg_1	315	317	PF00400	0.689
TRG_ER_diArg_1	65	67	PF00400	0.696
TRG_Pf-PMV_PEXEL_1	317	321	PF00026	0.699

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P3S8	Leptomonas seymouri	43%	98%
A0A3Q8ITW3	Leishmania donovani	89%	100%
A4HLB7	Leishmania braziliensis	63%	96%
E9AEH0	Leishmania major	85%	100%
E9AHN3	Leishmania infantum	89%	100%