Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9B3Q8_LEIMU

TriTrypDb:

LmxM.32.0760

Length:

373

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B3Q8

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B3Q8

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	246	250	PF00656	0.737
CLV_C14_Caspase3-7	87	91	PF00656	0.650
CLV_NRD_NRD_1	120	122	PF00675	0.577
CLV_NRD_NRD_1	345	347	PF00675	0.540
CLV_NRD_NRD_1	358	360	PF00675	0.562
CLV_NRD_NRD_1	40	42	PF00675	0.529
CLV_NRD_NRD_1	49	51	PF00675	0.563
CLV_PCSK_KEX2_1	115	117	PF00082	0.468
CLV_PCSK_KEX2_1	345	347	PF00082	0.540
CLV_PCSK_KEX2_1	358	360	PF00082	0.562
CLV_PCSK_KEX2_1	39	41	PF00082	0.533
CLV_PCSK_KEX2_1	49	51	PF00082	0.560
CLV_PCSK_PC1ET2_1	115	117	PF00082	0.633
CLV_PCSK_SKI1_1	111	115	PF00082	0.504
CLV_PCSK_SKI1_1	149	153	PF00082	0.474
CLV_PCSK_SKI1_1	224	228	PF00082	0.503
CLV_PCSK_SKI1_1	340	344	PF00082	0.622
DEG_SCF_FBW7_2	258	265	PF00400	0.620
DEG_SPOP_SBC_1	84	88	PF00917	0.489
DOC_MAPK_gen_1	307	314	PF00069	0.511
DOC_MAPK_MEF2A_6	136	144	PF00069	0.492
DOC_PP2B_LxvP_1	272	275	PF13499	0.738
DOC_PP2B_LxvP_1	298	301	PF13499	0.758
DOC_USP7_MATH_1	16	20	PF00917	0.622
DOC_USP7_MATH_1	209	213	PF00917	0.653
DOC_USP7_MATH_1	31	35	PF00917	0.606
DOC_USP7_MATH_1	74	78	PF00917	0.767
DOC_USP7_MATH_1	85	89	PF00917	0.609
DOC_USP7_UBL2_3	111	115	PF12436	0.622
DOC_USP7_UBL2_3	309	313	PF12436	0.577
DOC_WW_Pin1_4	207	212	PF00397	0.697
DOC_WW_Pin1_4	258	263	PF00397	0.747
DOC_WW_Pin1_4	291	296	PF00397	0.642
LIG_14-3-3_CanoR_1	215	222	PF00244	0.463
LIG_14-3-3_CanoR_1	363	369	PF00244	0.492
LIG_BIR_III_2	208	212	PF00653	0.615
LIG_BIR_III_4	249	253	PF00653	0.610
LIG_FHA_1	242	248	PF00498	0.572
LIG_FHA_1	259	265	PF00498	0.713
LIG_FHA_1	267	273	PF00498	0.554
LIG_FHA_1	309	315	PF00498	0.532
LIG_FHA_2	215	221	PF00498	0.510
LIG_FHA_2	274	280	PF00498	0.596
LIG_FHA_2	318	324	PF00498	0.502
LIG_FHA_2	85	91	PF00498	0.655
LIG_LIR_Gen_1	220	230	PF02991	0.571
LIG_LIR_LC3C_4	297	300	PF02991	0.520
LIG_LIR_Nem_3	145	151	PF02991	0.633
LIG_LIR_Nem_3	220	225	PF02991	0.564
LIG_SH2_CRK	148	152	PF00017	0.586
LIG_SH2_STAP1	222	226	PF00017	0.540
LIG_SH2_STAP1	29	33	PF00017	0.632
LIG_SH2_STAT3	14	17	PF00017	0.690
LIG_SH2_STAT3	192	195	PF00017	0.546
LIG_SH2_STAT5	192	195	PF00017	0.546
LIG_SH3_3	3	9	PF00018	0.584
LIG_TRAF2_1	123	126	PF00917	0.662
LIG_UBA3_1	113	122	PF00899	0.483
LIG_UBA3_1	335	343	PF00899	0.373
LIG_WRC_WIRS_1	69	74	PF05994	0.488
MOD_CK1_1	127	133	PF00069	0.524
MOD_CK1_1	19	25	PF00069	0.599
MOD_CK1_1	214	220	PF00069	0.560
MOD_CK1_1	251	257	PF00069	0.571
MOD_CK1_1	83	89	PF00069	0.575
MOD_CK2_1	195	201	PF00069	0.487
MOD_CK2_1	273	279	PF00069	0.599
MOD_CK2_1	31	37	PF00069	0.534
MOD_GlcNHglycan	10	13	PF01048	0.671
MOD_GlcNHglycan	124	129	PF01048	0.612
MOD_GlcNHglycan	211	214	PF01048	0.627
MOD_GlcNHglycan	22	25	PF01048	0.570
MOD_GlcNHglycan	236	239	PF01048	0.704
MOD_GlcNHglycan	249	253	PF01048	0.571
MOD_GlcNHglycan	326	329	PF01048	0.496
MOD_GlcNHglycan	33	36	PF01048	0.641
MOD_GlcNHglycan	368	371	PF01048	0.453
MOD_GlcNHglycan	64	67	PF01048	0.601
MOD_GlcNHglycan	72	75	PF01048	0.788
MOD_GlcNHglycan	77	80	PF01048	0.612
MOD_GlcNHglycan	82	85	PF01048	0.556
MOD_GlcNHglycan	87	90	PF01048	0.496
MOD_GSK3_1	16	23	PF00069	0.596
MOD_GSK3_1	203	210	PF00069	0.661
MOD_GSK3_1	211	218	PF00069	0.703
MOD_GSK3_1	260	267	PF00069	0.712
MOD_GSK3_1	290	297	PF00069	0.574
MOD_GSK3_1	364	371	PF00069	0.502
MOD_GSK3_1	70	77	PF00069	0.602
MOD_GSK3_1	80	87	PF00069	0.637
MOD_N-GLC_1	234	239	PF02516	0.739
MOD_NEK2_1	243	248	PF00069	0.683
MOD_NEK2_1	368	373	PF00069	0.544
MOD_NEK2_1	94	99	PF00069	0.519
MOD_PIKK_1	127	133	PF00454	0.524
MOD_PKA_2	214	220	PF00069	0.475
MOD_Plk_1	109	115	PF00069	0.553
MOD_Plk_2-3	180	186	PF00069	0.570
MOD_Plk_4	109	115	PF00069	0.566
MOD_Plk_4	294	300	PF00069	0.617
MOD_Plk_4	349	355	PF00069	0.629
MOD_ProDKin_1	207	213	PF00069	0.696
MOD_ProDKin_1	258	264	PF00069	0.745
MOD_ProDKin_1	291	297	PF00069	0.643
TRG_DiLeu_BaEn_2	138	144	PF01217	0.492
TRG_DiLeu_BaLyEn_6	226	231	PF01217	0.683
TRG_ENDOCYTIC_2	148	151	PF00928	0.476
TRG_ENDOCYTIC_2	222	225	PF00928	0.541
TRG_ER_diArg_1	39	41	PF00400	0.513
TRG_ER_diArg_1	49	51	PF00400	0.537

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I0S4	Leptomonas seymouri	40%	93%
A0A3S7X6J7	Leishmania donovani	80%	100%
A4HLB6	Leishmania braziliensis	65%	100%
A4I8U2	Leishmania infantum	80%	100%
Q4Q4C9	Leishmania major	78%	100%