Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9B3N2_LEIMU

TriTrypDb:

LmxM.32.0535

Length:

201

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 9
NetGPI	no	yes: 0, no: 9

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B3N2

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B3N2

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	114	118	PF00656	0.467
CLV_C14_Caspase3-7	16	20	PF00656	0.515
CLV_NRD_NRD_1	136	138	PF00675	0.612
CLV_PCSK_KEX2_1	136	138	PF00082	0.612
CLV_PCSK_SKI1_1	2	6	PF00082	0.536
CLV_PCSK_SKI1_1	77	81	PF00082	0.500
CLV_Separin_Metazoa	52	56	PF03568	0.487
DEG_Nend_UBRbox_1	1	4	PF02207	0.631
DOC_ANK_TNKS_1	172	179	PF00023	0.482
DOC_PP2B_LxvP_1	46	49	PF13499	0.531
DOC_PP4_FxxP_1	106	109	PF00568	0.622
DOC_PP4_FxxP_1	148	151	PF00568	0.545
DOC_WW_Pin1_4	61	66	PF00397	0.524
LIG_14-3-3_CanoR_1	127	131	PF00244	0.436
LIG_14-3-3_CanoR_1	187	191	PF00244	0.588
LIG_14-3-3_CanoR_1	24	32	PF00244	0.553
LIG_14-3-3_CanoR_1	39	47	PF00244	0.222
LIG_14-3-3_CanoR_1	77	85	PF00244	0.435
LIG_14-3-3_CanoR_1	99	103	PF00244	0.460
LIG_Actin_WH2_2	25	41	PF00022	0.548
LIG_BRCT_BRCA1_1	144	148	PF00533	0.575
LIG_EH1_1	127	135	PF00400	0.617
LIG_EH1_1	69	77	PF00400	0.477
LIG_eIF4E_1	128	134	PF01652	0.612
LIG_FHA_1	103	109	PF00498	0.556
LIG_FHA_1	145	151	PF00498	0.568
LIG_FHA_2	109	115	PF00498	0.604
LIG_FHA_2	24	30	PF00498	0.635
LIG_GBD_Chelix_1	156	164	PF00786	0.517
LIG_LIR_Apic_2	105	109	PF02991	0.625
LIG_LIR_Apic_2	145	151	PF02991	0.568
LIG_LIR_Gen_1	167	177	PF02991	0.494
LIG_LIR_Nem_3	167	172	PF02991	0.506
LIG_PCNA_yPIPBox_3	77	89	PF02747	0.525
LIG_SH2_NCK_1	128	132	PF00017	0.630
LIG_SH2_SRC	45	48	PF00017	0.460
LIG_SH2_STAP1	102	106	PF00017	0.370
LIG_SH2_STAT5	128	131	PF00017	0.632
LIG_SH2_STAT5	45	48	PF00017	0.417
LIG_SH2_STAT5	88	91	PF00017	0.497
LIG_SH3_3	171	177	PF00018	0.362
LIG_SH3_3	41	47	PF00018	0.476
LIG_SUMO_SIM_anti_2	50	55	PF11976	0.473
MOD_GlcNHglycan	139	143	PF01048	0.682
MOD_GSK3_1	138	145	PF00069	0.628
MOD_GSK3_1	151	158	PF00069	0.424
MOD_GSK3_1	176	183	PF00069	0.548
MOD_GSK3_1	23	30	PF00069	0.550
MOD_GSK3_1	34	41	PF00069	0.349
MOD_GSK3_1	61	68	PF00069	0.505
MOD_GSK3_1	98	105	PF00069	0.482
MOD_N-GLC_1	34	39	PF02516	0.270
MOD_NEK2_1	13	18	PF00069	0.505
MOD_NEK2_1	144	149	PF00069	0.597
MOD_NEK2_1	38	43	PF00069	0.418
MOD_NEK2_2	65	70	PF00069	0.554
MOD_PIKK_1	155	161	PF00454	0.511
MOD_PKA_2	126	132	PF00069	0.433
MOD_PKA_2	186	192	PF00069	0.584
MOD_PKA_2	23	29	PF00069	0.554
MOD_PKA_2	38	44	PF00069	0.225
MOD_PKA_2	8	14	PF00069	0.551
MOD_PKA_2	98	104	PF00069	0.383
MOD_Plk_1	28	34	PF00069	0.592
MOD_Plk_4	129	135	PF00069	0.598
MOD_Plk_4	144	150	PF00069	0.583
MOD_Plk_4	176	182	PF00069	0.412
MOD_Plk_4	186	192	PF00069	0.453
MOD_Plk_4	8	14	PF00069	0.582
MOD_ProDKin_1	61	67	PF00069	0.519
TRG_ER_diArg_1	135	137	PF00400	0.566
TRG_NES_CRM1_1	155	167	PF08389	0.424

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1ILI4	Leptomonas seymouri	49%	89%
A0A1X0P1T8	Trypanosomatidae	26%	77%
A0A3S5IQJ3	Trypanosoma rangeli	27%	84%
A0A3S7X6D3	Leishmania donovani	93%	100%
A4HL90	Leishmania braziliensis	85%	100%
E9AHN2	Leishmania infantum	92%	100%
Q4Q4F5	Leishmania major	91%	100%
V5AM33	Trypanosoma cruzi	29%	82%