Putative DNA mismatch repair protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

DNA mismatch repair protein MSH2, putative

Species:

Leishmania mexicana

UniProt:

E9B3L9_LEIMU

TriTrypDb:

LmxM.32.0410

Length:

939

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

Cellular components
Term	Name	Level	Count
GO:0005634	nucleus	5	12
GO:0032300	mismatch repair complex	2	12
GO:0032991	protein-containing complex	1	12
GO:0043226	organelle	2	12
GO:0043227	membrane-bounded organelle	3	12
GO:0043229	intracellular organelle	3	12
GO:0043231	intracellular membrane-bounded organelle	4	12
GO:0110165	cellular anatomical entity	1	12
GO:0005737	cytoplasm	2	1
GO:0032301	MutSalpha complex	3	1
GO:0140513	nuclear protein-containing complex	2	1

Expansion

Sequence features

E9B3L9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B3L9

Function

Biological processes
Term	Name	Level	Count
GO:0006139	nucleobase-containing compound metabolic process	3	12
GO:0006259	DNA metabolic process	4	12
GO:0006281	DNA repair	5	12
GO:0006298	mismatch repair	6	12
GO:0006725	cellular aromatic compound metabolic process	3	12
GO:0006807	nitrogen compound metabolic process	2	12
GO:0006950	response to stress	2	12
GO:0006974	DNA damage response	4	12
GO:0008152	metabolic process	1	12
GO:0009987	cellular process	1	12
GO:0033554	cellular response to stress	3	12
GO:0034641	cellular nitrogen compound metabolic process	3	12
GO:0043170	macromolecule metabolic process	3	12
GO:0044237	cellular metabolic process	2	12
GO:0044238	primary metabolic process	2	12
GO:0044260	obsolete cellular macromolecule metabolic process	3	12
GO:0046483	heterocycle metabolic process	3	12
GO:0050896	response to stimulus	1	12
GO:0051716	cellular response to stimulus	2	12
GO:0071704	organic substance metabolic process	2	12
GO:0090304	nucleic acid metabolic process	4	12
GO:1901360	organic cyclic compound metabolic process	3	12
GO:0006310	DNA recombination	5	1
GO:0006312	mitotic recombination	6	1

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	12
GO:0003676	nucleic acid binding	3	12
GO:0003677	DNA binding	4	12
GO:0003690	double-stranded DNA binding	5	12
GO:0003824	catalytic activity	1	12
GO:0005488	binding	1	12
GO:0005524	ATP binding	5	12
GO:0008094	ATP-dependent activity, acting on DNA	2	12
GO:0017076	purine nucleotide binding	4	12
GO:0030554	adenyl nucleotide binding	5	12
GO:0030983	mismatched DNA binding	6	12
GO:0032553	ribonucleotide binding	3	12
GO:0032555	purine ribonucleotide binding	4	12
GO:0032559	adenyl ribonucleotide binding	5	12
GO:0035639	purine ribonucleoside triphosphate binding	4	12
GO:0036094	small molecule binding	2	12
GO:0043167	ion binding	2	12
GO:0043168	anion binding	3	12
GO:0097159	organic cyclic compound binding	2	12
GO:0097367	carbohydrate derivative binding	2	12
GO:0140097	catalytic activity, acting on DNA	3	12
GO:0140299	small molecule sensor activity	1	12
GO:0140612	DNA damage sensor activity	2	12
GO:0140640	catalytic activity, acting on a nucleic acid	2	12
GO:0140657	ATP-dependent activity	1	12
GO:0140664	ATP-dependent DNA damage sensor activity	3	12
GO:1901265	nucleoside phosphate binding	3	12
GO:1901363	heterocyclic compound binding	2	12

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	176	180	PF00656	0.356
CLV_C14_Caspase3-7	3	7	PF00656	0.500
CLV_C14_Caspase3-7	545	549	PF00656	0.410
CLV_MEL_PAP_1	725	731	PF00089	0.210
CLV_NRD_NRD_1	217	219	PF00675	0.431
CLV_NRD_NRD_1	295	297	PF00675	0.490
CLV_NRD_NRD_1	395	397	PF00675	0.254
CLV_NRD_NRD_1	400	402	PF00675	0.277
CLV_NRD_NRD_1	527	529	PF00675	0.210
CLV_NRD_NRD_1	565	567	PF00675	0.240
CLV_NRD_NRD_1	579	581	PF00675	0.221
CLV_NRD_NRD_1	89	91	PF00675	0.399
CLV_NRD_NRD_1	892	894	PF00675	0.573
CLV_PCSK_KEX2_1	217	219	PF00082	0.431
CLV_PCSK_KEX2_1	295	297	PF00082	0.490
CLV_PCSK_KEX2_1	386	388	PF00082	0.227
CLV_PCSK_KEX2_1	400	402	PF00082	0.257
CLV_PCSK_KEX2_1	565	567	PF00082	0.312
CLV_PCSK_KEX2_1	579	581	PF00082	0.312
CLV_PCSK_KEX2_1	89	91	PF00082	0.398
CLV_PCSK_KEX2_1	900	902	PF00082	0.448
CLV_PCSK_KEX2_1	919	921	PF00082	0.300
CLV_PCSK_PC1ET2_1	386	388	PF00082	0.312
CLV_PCSK_PC1ET2_1	579	581	PF00082	0.264
CLV_PCSK_PC1ET2_1	900	902	PF00082	0.448
CLV_PCSK_PC1ET2_1	919	921	PF00082	0.327
CLV_PCSK_PC7_1	396	402	PF00082	0.235
CLV_PCSK_SKI1_1	188	192	PF00082	0.349
CLV_PCSK_SKI1_1	377	381	PF00082	0.235
CLV_PCSK_SKI1_1	434	438	PF00082	0.314
CLV_PCSK_SKI1_1	510	514	PF00082	0.235
CLV_PCSK_SKI1_1	919	923	PF00082	0.465
CLV_Separin_Metazoa	253	257	PF03568	0.469
DEG_APCC_DBOX_1	656	664	PF00400	0.320
DEG_APCC_DBOX_1	931	939	PF00400	0.544
DOC_CYCLIN_RxL_1	159	170	PF00134	0.384
DOC_CYCLIN_RxL_1	396	408	PF00134	0.514
DOC_CYCLIN_RxL_1	914	924	PF00134	0.408
DOC_CYCLIN_yClb5_NLxxxL_5	182	191	PF00134	0.353
DOC_MAPK_gen_1	396	405	PF00069	0.410
DOC_MAPK_gen_1	535	543	PF00069	0.421
DOC_MAPK_gen_1	654	663	PF00069	0.380
DOC_MAPK_gen_1	790	797	PF00069	0.453
DOC_MAPK_gen_1	919	925	PF00069	0.349
DOC_MAPK_HePTP_8	651	663	PF00069	0.377
DOC_MAPK_MEF2A_6	222	229	PF00069	0.475
DOC_MAPK_MEF2A_6	363	371	PF00069	0.421
DOC_MAPK_MEF2A_6	654	663	PF00069	0.380
DOC_MAPK_MEF2A_6	697	705	PF00069	0.410
DOC_PP1_RVXF_1	160	167	PF00149	0.415
DOC_PP2B_LxvP_1	255	258	PF13499	0.323
DOC_USP7_MATH_1	102	106	PF00917	0.417
DOC_USP7_MATH_1	136	140	PF00917	0.426
DOC_USP7_MATH_1	878	882	PF00917	0.694
DOC_USP7_MATH_2	258	264	PF00917	0.364
DOC_USP7_UBL2_3	890	894	PF12436	0.278
DOC_WW_Pin1_4	110	115	PF00397	0.364
LIG_14-3-3_CanoR_1	162	167	PF00244	0.313
LIG_14-3-3_CanoR_1	212	219	PF00244	0.448
LIG_14-3-3_CanoR_1	261	265	PF00244	0.367
LIG_14-3-3_CanoR_1	295	299	PF00244	0.374
LIG_14-3-3_CanoR_1	363	367	PF00244	0.410
LIG_14-3-3_CanoR_1	400	404	PF00244	0.486
LIG_14-3-3_CanoR_1	471	477	PF00244	0.470
LIG_14-3-3_CanoR_1	532	541	PF00244	0.506
LIG_14-3-3_CanoR_1	551	560	PF00244	0.331
LIG_14-3-3_CanoR_1	769	775	PF00244	0.410
LIG_14-3-3_CanoR_1	790	796	PF00244	0.512
LIG_14-3-3_CanoR_1	831	837	PF00244	0.421
LIG_14-3-3_CanoR_1	89	95	PF00244	0.344
LIG_14-3-3_CanoR_1	893	902	PF00244	0.500
LIG_Actin_WH2_2	391	408	PF00022	0.477
LIG_Actin_WH2_2	519	537	PF00022	0.512
LIG_Actin_WH2_2	75	91	PF00022	0.337
LIG_Actin_WH2_2	816	833	PF00022	0.421
LIG_APCC_ABBA_1	367	372	PF00400	0.512
LIG_BIR_II_1	1	5	PF00653	0.468
LIG_BIR_III_2	646	650	PF00653	0.419
LIG_BRCT_BRCA1_1	138	142	PF00533	0.361
LIG_CaM_IQ_9	232	248	PF13499	0.430
LIG_Clathr_ClatBox_1	124	128	PF01394	0.413
LIG_CtBP_PxDLS_1	686	692	PF00389	0.410
LIG_deltaCOP1_diTrp_1	869	873	PF00928	0.549
LIG_eIF4E_1	606	612	PF01652	0.413
LIG_FHA_1	168	174	PF00498	0.340
LIG_FHA_1	379	385	PF00498	0.485
LIG_FHA_1	51	57	PF00498	0.356
LIG_FHA_1	535	541	PF00498	0.555
LIG_FHA_1	600	606	PF00498	0.512
LIG_FHA_1	629	635	PF00498	0.648
LIG_FHA_1	677	683	PF00498	0.377
LIG_FHA_1	730	736	PF00498	0.410
LIG_FHA_1	739	745	PF00498	0.410
LIG_FHA_1	758	764	PF00498	0.410
LIG_FHA_2	116	122	PF00498	0.426
LIG_FHA_2	174	180	PF00498	0.349
LIG_FHA_2	204	210	PF00498	0.531
LIG_FHA_2	229	235	PF00498	0.371
LIG_FHA_2	363	369	PF00498	0.477
LIG_FHA_2	454	460	PF00498	0.461
LIG_FHA_2	473	479	PF00498	0.477
LIG_FHA_2	543	549	PF00498	0.447
LIG_GBD_Chelix_1	582	590	PF00786	0.264
LIG_LIR_Apic_2	427	431	PF02991	0.489
LIG_LIR_Apic_2	438	443	PF02991	0.381
LIG_LIR_Gen_1	300	310	PF02991	0.316
LIG_LIR_Gen_1	408	419	PF02991	0.479
LIG_LIR_Gen_1	798	808	PF02991	0.410
LIG_LIR_Gen_1	869	878	PF02991	0.573
LIG_LIR_Nem_3	165	169	PF02991	0.283
LIG_LIR_Nem_3	300	305	PF02991	0.333
LIG_LIR_Nem_3	328	334	PF02991	0.410
LIG_LIR_Nem_3	408	414	PF02991	0.479
LIG_LIR_Nem_3	495	501	PF02991	0.512
LIG_LIR_Nem_3	519	523	PF02991	0.412
LIG_LIR_Nem_3	561	567	PF02991	0.435
LIG_LIR_Nem_3	588	592	PF02991	0.410
LIG_LIR_Nem_3	652	656	PF02991	0.446
LIG_LIR_Nem_3	771	777	PF02991	0.410
LIG_LIR_Nem_3	798	804	PF02991	0.512
LIG_LIR_Nem_3	844	848	PF02991	0.449
LIG_LIR_Nem_3	869	873	PF02991	0.549
LIG_NRBOX	186	192	PF00104	0.349
LIG_PCNA_yPIPBox_3	373	387	PF02747	0.512
LIG_PDZ_Class_3	934	939	PF00595	0.476
LIG_Pex14_1	40	44	PF04695	0.406
LIG_Pex14_2	777	781	PF04695	0.410
LIG_PTB_Apo_2	813	820	PF02174	0.410
LIG_SH2_CRK	428	432	PF00017	0.464
LIG_SH2_CRK	498	502	PF00017	0.430
LIG_SH2_CRK	520	524	PF00017	0.410
LIG_SH2_CRK	564	568	PF00017	0.435
LIG_SH2_PTP2	440	443	PF00017	0.418
LIG_SH2_SRC	589	592	PF00017	0.435
LIG_SH2_STAP1	169	173	PF00017	0.234
LIG_SH2_STAP1	898	902	PF00017	0.387
LIG_SH2_STAT3	834	837	PF00017	0.455
LIG_SH2_STAT5	106	109	PF00017	0.406
LIG_SH2_STAT5	169	172	PF00017	0.349
LIG_SH2_STAT5	293	296	PF00017	0.351
LIG_SH2_STAT5	36	39	PF00017	0.337
LIG_SH2_STAT5	428	431	PF00017	0.466
LIG_SH2_STAT5	440	443	PF00017	0.373
LIG_SH2_STAT5	49	52	PF00017	0.321
LIG_SH2_STAT5	522	525	PF00017	0.410
LIG_SH2_STAT5	589	592	PF00017	0.410
LIG_SH2_STAT5	606	609	PF00017	0.410
LIG_SH2_STAT5	834	837	PF00017	0.493
LIG_SH2_STAT5	848	851	PF00017	0.361
LIG_SH2_STAT5	934	937	PF00017	0.572
LIG_SH3_3	280	286	PF00018	0.513
LIG_SH3_3	368	374	PF00018	0.421
LIG_SUMO_SIM_anti_2	311	317	PF11976	0.335
LIG_SUMO_SIM_anti_2	631	636	PF11976	0.606
LIG_SUMO_SIM_anti_2	759	766	PF11976	0.410
LIG_SUMO_SIM_par_1	539	546	PF11976	0.435
LIG_SUMO_SIM_par_1	759	766	PF11976	0.452
LIG_TRAF2_1	886	889	PF00917	0.357
LIG_TRFH_1	834	838	PF08558	0.410
LIG_Vh1_VBS_1	746	764	PF01044	0.477
LIG_WRC_WIRS_1	650	655	PF05994	0.449
LIG_WRC_WIRS_1	739	744	PF05994	0.410
MOD_CK1_1	197	203	PF00069	0.403
MOD_CK1_1	228	234	PF00069	0.510
MOD_CK1_1	28	34	PF00069	0.425
MOD_CK1_1	329	335	PF00069	0.432
MOD_CK1_1	60	66	PF00069	0.570
MOD_CK1_1	751	757	PF00069	0.484
MOD_CK1_1	826	832	PF00069	0.430
MOD_CK2_1	115	121	PF00069	0.412
MOD_CK2_1	162	168	PF00069	0.312
MOD_CK2_1	228	234	PF00069	0.410
MOD_CK2_1	362	368	PF00069	0.421
MOD_CK2_1	453	459	PF00069	0.490
MOD_CK2_1	524	530	PF00069	0.427
MOD_CK2_1	533	539	PF00069	0.412
MOD_GlcNHglycan	136	139	PF01048	0.403
MOD_GlcNHglycan	196	199	PF01048	0.506
MOD_GlcNHglycan	306	309	PF01048	0.457
MOD_GlcNHglycan	60	63	PF01048	0.484
MOD_GlcNHglycan	643	646	PF01048	0.600
MOD_GlcNHglycan	65	68	PF01048	0.531
MOD_GlcNHglycan	748	751	PF01048	0.210
MOD_GlcNHglycan	811	814	PF01048	0.325
MOD_GlcNHglycan	824	828	PF01048	0.242
MOD_GlcNHglycan	881	884	PF01048	0.590
MOD_GlcNHglycan	895	898	PF01048	0.390
MOD_GSK3_1	169	176	PF00069	0.434
MOD_GSK3_1	193	200	PF00069	0.502
MOD_GSK3_1	294	301	PF00069	0.367
MOD_GSK3_1	322	329	PF00069	0.421
MOD_GSK3_1	426	433	PF00069	0.510
MOD_GSK3_1	458	465	PF00069	0.434
MOD_GSK3_1	539	546	PF00069	0.419
MOD_GSK3_1	57	64	PF00069	0.516
MOD_GSK3_1	637	644	PF00069	0.509
MOD_GSK3_1	691	698	PF00069	0.410
MOD_GSK3_1	791	798	PF00069	0.483
MOD_GSK3_1	826	833	PF00069	0.434
MOD_GSK3_1	98	105	PF00069	0.511
MOD_N-GLC_1	115	120	PF02516	0.398
MOD_N-GLC_1	157	162	PF02516	0.324
MOD_N-GLC_1	472	477	PF02516	0.249
MOD_N-GLC_2	335	337	PF02516	0.210
MOD_NEK2_1	120	125	PF00069	0.378
MOD_NEK2_1	134	139	PF00069	0.313
MOD_NEK2_1	157	162	PF00069	0.365
MOD_NEK2_1	173	178	PF00069	0.371
MOD_NEK2_1	294	299	PF00069	0.402
MOD_NEK2_1	405	410	PF00069	0.439
MOD_NEK2_1	487	492	PF00069	0.513
MOD_NEK2_1	524	529	PF00069	0.421
MOD_NEK2_1	582	587	PF00069	0.412
MOD_NEK2_1	673	678	PF00069	0.409
MOD_NEK2_1	682	687	PF00069	0.387
MOD_NEK2_1	746	751	PF00069	0.410
MOD_NEK2_1	795	800	PF00069	0.412
MOD_NEK2_1	830	835	PF00069	0.416
MOD_NEK2_2	649	654	PF00069	0.388
MOD_PIKK_1	405	411	PF00454	0.512
MOD_PIKK_1	487	493	PF00454	0.464
MOD_PIKK_1	674	680	PF00454	0.308
MOD_PIKK_1	754	760	PF00454	0.461
MOD_PIKK_1	802	808	PF00454	0.421
MOD_PK_1	90	96	PF00069	0.332
MOD_PKA_1	565	571	PF00069	0.464
MOD_PKA_1	57	63	PF00069	0.413
MOD_PKA_1	893	899	PF00069	0.564
MOD_PKA_2	211	217	PF00069	0.417
MOD_PKA_2	260	266	PF00069	0.372
MOD_PKA_2	28	34	PF00069	0.464
MOD_PKA_2	294	300	PF00069	0.371
MOD_PKA_2	322	328	PF00069	0.421
MOD_PKA_2	362	368	PF00069	0.410
MOD_PKA_2	399	405	PF00069	0.443
MOD_PKA_2	524	530	PF00069	0.415
MOD_PKA_2	534	540	PF00069	0.401
MOD_PKA_2	565	571	PF00069	0.512
MOD_PKA_2	768	774	PF00069	0.422
MOD_PKA_2	791	797	PF00069	0.508
MOD_PKA_2	830	836	PF00069	0.421
MOD_PKA_2	98	104	PF00069	0.442
MOD_Plk_1	120	126	PF00069	0.407
MOD_Plk_1	157	163	PF00069	0.311
MOD_Plk_1	203	209	PF00069	0.594
MOD_Plk_1	458	464	PF00069	0.427
MOD_Plk_1	472	478	PF00069	0.406
MOD_Plk_1	802	808	PF00069	0.421
MOD_Plk_2-3	260	266	PF00069	0.372
MOD_Plk_2-3	869	875	PF00069	0.512
MOD_Plk_4	102	108	PF00069	0.595
MOD_Plk_4	120	126	PF00069	0.404
MOD_Plk_4	136	142	PF00069	0.248
MOD_Plk_4	298	304	PF00069	0.341
MOD_Plk_4	326	332	PF00069	0.410
MOD_Plk_4	362	368	PF00069	0.410
MOD_Plk_4	40	46	PF00069	0.391
MOD_Plk_4	453	459	PF00069	0.484
MOD_Plk_4	585	591	PF00069	0.419
MOD_Plk_4	630	636	PF00069	0.647
MOD_Plk_4	691	697	PF00069	0.410
MOD_Plk_4	738	744	PF00069	0.410
MOD_Plk_4	748	754	PF00069	0.410
MOD_Plk_4	791	797	PF00069	0.477
MOD_Plk_4	855	861	PF00069	0.505
MOD_ProDKin_1	110	116	PF00069	0.363
MOD_SUMO_for_1	436	439	PF00179	0.512
MOD_SUMO_for_1	512	515	PF00179	0.410
MOD_SUMO_for_1	635	638	PF00179	0.679
MOD_SUMO_for_1	921	924	PF00179	0.499
MOD_SUMO_rev_2	594	599	PF00179	0.410
MOD_SUMO_rev_2	882	892	PF00179	0.351
TRG_DiLeu_BaEn_1	311	316	PF01217	0.512
TRG_DiLeu_BaEn_4	259	265	PF01217	0.436
TRG_DiLeu_BaLyEn_6	646	651	PF01217	0.426
TRG_ENDOCYTIC_2	302	305	PF00928	0.440
TRG_ENDOCYTIC_2	498	501	PF00928	0.512
TRG_ENDOCYTIC_2	520	523	PF00928	0.410
TRG_ENDOCYTIC_2	564	567	PF00928	0.435
TRG_ENDOCYTIC_2	589	592	PF00928	0.410
TRG_ENDOCYTIC_2	774	777	PF00928	0.410
TRG_ENDOCYTIC_2	801	804	PF00928	0.335
TRG_ER_diArg_1	216	218	PF00400	0.428
TRG_ER_diArg_1	294	296	PF00400	0.493
TRG_ER_diArg_1	564	566	PF00400	0.512
TRG_ER_diArg_1	789	792	PF00400	0.500
TRG_ER_diArg_1	88	90	PF00400	0.393
TRG_NES_CRM1_1	358	372	PF08389	0.421
TRG_NES_CRM1_1	733	748	PF08389	0.410
TRG_NLS_Bipartite_1	565	583	PF00514	0.512
TRG_NLS_MonoExtC_3	578	584	PF00514	0.477
TRG_NLS_MonoExtC_3	918	924	PF00514	0.322
TRG_Pf-PMV_PEXEL_1	217	221	PF00026	0.351
TRG_Pf-PMV_PEXEL_1	230	234	PF00026	0.390
TRG_Pf-PMV_PEXEL_1	455	459	PF00026	0.253
TRG_Pf-PMV_PEXEL_1	565	569	PF00026	0.304
TRG_Pf-PMV_PEXEL_1	580	584	PF00026	0.332
TRG_Pf-PMV_PEXEL_1	903	907	PF00026	0.524

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I6N3	Leptomonas seymouri	81%	99%
A0A0S4J224	Bodo saltans	50%	100%
A0A1X0P1A3	Trypanosomatidae	59%	98%
A0A3Q8IGP6	Leishmania donovani	96%	100%
A0A3R7KEP9	Trypanosoma rangeli	59%	98%
A1B095	Paracoccus denitrificans (strain Pd 1222)	28%	100%
A3CR17	Streptococcus sanguinis (strain SK36)	28%	100%
A4HL76	Leishmania braziliensis	89%	100%
A4I8Q5	Leishmania infantum	96%	100%
A4JFW7	Burkholderia vietnamiensis (strain G4 / LMG 22486)	28%	100%
A8FDH3	Bacillus pumilus (strain SAFR-032)	31%	100%
B0TK13	Shewanella halifaxensis (strain HAW-EB4)	29%	100%
B0VAU7	Acinetobacter baumannii (strain AYE)	29%	100%
B0VUC9	Acinetobacter baumannii (strain SDF)	30%	100%
B1KSA3	Clostridium botulinum (strain Loch Maree / Type A3)	28%	100%
B2HX50	Acinetobacter baumannii (strain ACICU)	29%	100%
B3EEE1	Chlorobium limicola (strain DSM 245 / NBRC 103803 / 6330)	31%	100%
B7GW85	Acinetobacter baumannii (strain AB307-0294)	29%	100%
B7IBV9	Acinetobacter baumannii (strain AB0057)	29%	100%
B8CJQ5	Shewanella piezotolerans (strain WP3 / JCM 13877)	31%	100%
B9K800	Thermotoga neapolitana (strain ATCC 49049 / DSM 4359 / NBRC 107923 / NS-E)	27%	100%
C0QFS1	Desulforapulum autotrophicum (strain ATCC 43914 / DSM 3382 / VKM B-1955 / HRM2)	29%	100%
D0A4P2	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	57%	99%
O13396	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	31%	100%
O24617	Arabidopsis thaliana	32%	100%
O74502	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	27%	75%
O74773	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	32%	96%
P25847	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	29%	97%
P43246	Homo sapiens	33%	100%
P43247	Mus musculus	33%	100%
P43248	Drosophila melanogaster	32%	100%
P54275	Rattus norvegicus	33%	100%
P61672	Treponema denticola (strain ATCC 35405 / DSM 14222 / CIP 103919 / JCM 8153 / KCTC 15104)	30%	100%
Q03R33	Levilactobacillus brevis (strain ATCC 367 / BCRC 12310 / CIP 105137 / JCM 1170 / LMG 11437 / NCIMB 947 / NCTC 947)	30%	100%
Q07V29	Rhodopseudomonas palustris (strain BisA53)	31%	100%
Q10YG4	Trichodesmium erythraeum (strain IMS101)	27%	100%
Q1MRT4	Lawsonia intracellularis (strain PHE/MN1-00)	29%	100%
Q1WT15	Ligilactobacillus salivarius (strain UCC118)	30%	100%
Q24X61	Desulfitobacterium hafniense (strain Y51)	31%	100%
Q2JT35	Synechococcus sp. (strain JA-3-3Ab)	31%	100%
Q3M892	Trichormus variabilis (strain ATCC 29413 / PCC 7937)	28%	100%
Q3MHE4	Bos taurus	33%	100%
Q4Q4J6	Leishmania major	96%	100%
Q553L4	Dictyostelium discoideum	32%	100%
Q5LWH0	Ruegeria pomeroyi (strain ATCC 700808 / DSM 15171 / DSS-3)	28%	100%
Q5NYP9	Aromatoleum aromaticum (strain EbN1)	31%	100%
Q5XXB5	Chlorocebus aethiops	33%	100%
Q60BA1	Methylococcus capsulatus (strain ATCC 33009 / NCIMB 11132 / Bath)	30%	100%
Q65JE2	Bacillus licheniformis (strain ATCC 14580 / DSM 13 / JCM 2505 / CCUG 7422 / NBRC 12200 / NCIMB 9375 / NCTC 10341 / NRRL NRS-1264 / Gibson 46)	31%	100%
Q6G542	Bartonella henselae (strain ATCC 49882 / DSM 28221 / Houston 1)	28%	100%
Q7V9M5	Prochlorococcus marinus (strain SARG / CCMP1375 / SS120)	29%	100%
Q8RFK2	Fusobacterium nucleatum subsp. nucleatum (strain ATCC 25586 / DSM 15643 / BCRC 10681 / CIP 101130 / JCM 8532 / KCTC 2640 / LMG 13131 / VPI 4355)	28%	100%
Q9XGC9	Zea mays	31%	100%
V5BB82	Trypanosoma cruzi	59%	98%
V5BK71	Trypanosoma cruzi	28%	100%