LeishMANIAdb
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Mpv17/PMP22 family protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Mpv17/PMP22 family protein
Gene product:
Mpv17 / PMP22 family, putative
Species:
Leishmania mexicana
UniProt:
E9B3K6_LEIMU
TriTrypDb:
LmxM.32.0270
Length:
355

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 8
NetGPI no yes: 0, no: 8
Cellular components
TermNameLevelCount
GO:0005737 cytoplasm 2 1
GO:0016020 membrane 2 9
GO:0110165 cellular anatomical entity 1 9
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Expansion

Sequence features

E9B3K6
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B3K6

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 107 111 PF00656 0.534
CLV_C14_Caspase3-7 191 195 PF00656 0.419
CLV_NRD_NRD_1 120 122 PF00675 0.280
CLV_NRD_NRD_1 197 199 PF00675 0.637
CLV_NRD_NRD_1 282 284 PF00675 0.545
CLV_PCSK_KEX2_1 120 122 PF00082 0.280
CLV_PCSK_KEX2_1 155 157 PF00082 0.602
CLV_PCSK_KEX2_1 196 198 PF00082 0.627
CLV_PCSK_KEX2_1 282 284 PF00082 0.590
CLV_PCSK_PC1ET2_1 155 157 PF00082 0.590
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N1PA32 Leptomonas seymouri 68% 100%
A0A0S4JM85 Bodo saltans 30% 100%
A0A3Q8IGN8 Leishmania donovani 93% 100%
A0A3S5IR52 Trypanosoma rangeli 31% 100%
A4HL63 Leishmania braziliensis 82% 100%
E9AHM7 Leishmania infantum 93% 100%
Q4Q4J3 Leishmania major 90% 100%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS