STI1 domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9B3K0_LEIMU

TriTrypDb:

LmxM.32.0220

Length:

203

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 9
NetGPI	no	yes: 0, no: 9

Cellular components
Term	Name	Level	Count
GO:0005739	mitochondrion	5	1
GO:0020023	kinetoplast	2	1
GO:0043226	organelle	2	1
GO:0043227	membrane-bounded organelle	3	1
GO:0043229	intracellular organelle	3	1
GO:0043231	intracellular membrane-bounded organelle	4	1
GO:0110165	cellular anatomical entity	1	1

Expansion

Sequence features

E9B3K0

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B3K0

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	176	178	PF00675	0.472
CLV_NRD_NRD_1	18	20	PF00675	0.589
CLV_NRD_NRD_1	2	4	PF00675	0.583
CLV_NRD_NRD_1	7	9	PF00675	0.567
CLV_PCSK_KEX2_1	18	20	PF00082	0.589
CLV_PCSK_KEX2_1	2	4	PF00082	0.583
CLV_PCSK_KEX2_1	7	9	PF00082	0.567
CLV_PCSK_PC7_1	3	9	PF00082	0.591
CLV_PCSK_SKI1_1	125	129	PF00082	0.453
CLV_PCSK_SKI1_1	18	22	PF00082	0.610
DEG_Nend_UBRbox_1	1	4	PF02207	0.637
DOC_PP2B_LxvP_1	152	155	PF13499	0.615
DOC_USP7_MATH_1	103	107	PF00917	0.642
DOC_USP7_MATH_1	13	17	PF00917	0.498
DOC_WW_Pin1_4	40	45	PF00397	0.536
DOC_WW_Pin1_4	78	83	PF00397	0.515
LIG_14-3-3_CanoR_1	18	27	PF00244	0.596
LIG_FHA_1	133	139	PF00498	0.481
LIG_FHA_1	15	21	PF00498	0.493
LIG_FHA_1	189	195	PF00498	0.712
LIG_FHA_2	156	162	PF00498	0.601
LIG_LIR_Nem_3	24	30	PF02991	0.514
LIG_MYND_1	40	44	PF01753	0.486
LIG_Pex14_2	53	57	PF04695	0.487
LIG_PTB_Apo_2	51	58	PF02174	0.536
MOD_CDK_SPxxK_3	78	85	PF00069	0.538
MOD_CK1_1	87	93	PF00069	0.601
MOD_Cter_Amidation	119	122	PF01082	0.460
MOD_GlcNHglycan	60	63	PF01048	0.498
MOD_GlcNHglycan	93	96	PF01048	0.626
MOD_GSK3_1	28	35	PF00069	0.516
MOD_GSK3_1	87	94	PF00069	0.644
MOD_N-GLC_1	78	83	PF02516	0.585
MOD_NEK2_1	14	19	PF00069	0.614
MOD_NEK2_1	72	77	PF00069	0.530
MOD_NEK2_1	84	89	PF00069	0.537
MOD_NEK2_1	91	96	PF00069	0.616
MOD_PIKK_1	67	73	PF00454	0.617
MOD_PKA_2	84	90	PF00069	0.532
MOD_Plk_1	150	156	PF00069	0.675
MOD_Plk_4	87	93	PF00069	0.633
MOD_ProDKin_1	40	46	PF00069	0.538
MOD_ProDKin_1	78	84	PF00069	0.510
MOD_SUMO_rev_2	195	201	PF00179	0.616
TRG_DiLeu_BaLyEn_6	16	21	PF01217	0.540
TRG_ENDOCYTIC_2	130	133	PF00928	0.516
TRG_ENDOCYTIC_2	27	30	PF00928	0.558
TRG_ER_diArg_1	1	3	PF00400	0.617
TRG_ER_diArg_1	18	20	PF00400	0.582
TRG_ER_diArg_1	6	8	PF00400	0.585
TRG_Pf-PMV_PEXEL_1	18	23	PF00026	0.598

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I5B0	Leptomonas seymouri	70%	100%
A0A0S4KJX2	Bodo saltans	38%	100%
A0A1X0P0N3	Trypanosomatidae	46%	94%
A0A3S7X6E1	Leishmania donovani	91%	100%
A0A422NG89	Trypanosoma rangeli	51%	94%
A4I8N9	Leishmania infantum	91%	79%
D0A4L5	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	52%	95%
Q4Q4K1	Leishmania major	95%	100%