Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein

Species:

Leishmania mexicana

UniProt:

E9B3I9_LEIMU

TriTrypDb:

LmxM.32.0115

Length:

303

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B3I9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B3I9

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	207	211	PF00656	0.515
CLV_NRD_NRD_1	121	123	PF00675	0.737
CLV_NRD_NRD_1	171	173	PF00675	0.424
CLV_NRD_NRD_1	231	233	PF00675	0.640
CLV_NRD_NRD_1	262	264	PF00675	0.596
CLV_NRD_NRD_1	296	298	PF00675	0.506
CLV_NRD_NRD_1	299	301	PF00675	0.561
CLV_NRD_NRD_1	71	73	PF00675	0.511
CLV_NRD_NRD_1	97	99	PF00675	0.608
CLV_PCSK_FUR_1	297	301	PF00082	0.511
CLV_PCSK_KEX2_1	171	173	PF00082	0.428
CLV_PCSK_KEX2_1	188	190	PF00082	0.520
CLV_PCSK_KEX2_1	230	232	PF00082	0.541
CLV_PCSK_KEX2_1	262	264	PF00082	0.596
CLV_PCSK_KEX2_1	296	298	PF00082	0.506
CLV_PCSK_KEX2_1	299	301	PF00082	0.561
CLV_PCSK_KEX2_1	71	73	PF00082	0.511
CLV_PCSK_KEX2_1	97	99	PF00082	0.608
CLV_PCSK_PC1ET2_1	188	190	PF00082	0.408
CLV_PCSK_PC7_1	93	99	PF00082	0.507
CLV_PCSK_SKI1_1	285	289	PF00082	0.481
DEG_SPOP_SBC_1	100	104	PF00917	0.594
DOC_MAPK_gen_1	185	193	PF00069	0.432
DOC_MAPK_gen_1	48	56	PF00069	0.430
DOC_USP7_MATH_1	100	104	PF00917	0.664
DOC_USP7_MATH_1	173	177	PF00917	0.398
DOC_WW_Pin1_4	117	122	PF00397	0.666
DOC_WW_Pin1_4	127	132	PF00397	0.494
DOC_WW_Pin1_4	31	36	PF00397	0.647
LIG_14-3-3_CanoR_1	112	117	PF00244	0.539
LIG_14-3-3_CanoR_1	156	162	PF00244	0.448
LIG_14-3-3_CanoR_1	172	178	PF00244	0.447
LIG_14-3-3_CanoR_1	239	244	PF00244	0.522
LIG_14-3-3_CanoR_1	272	281	PF00244	0.446
LIG_CtBP_PxDLS_1	43	47	PF00389	0.443
LIG_FHA_1	252	258	PF00498	0.526
LIG_FHA_2	158	164	PF00498	0.435
LIG_FHA_2	205	211	PF00498	0.469
LIG_RPA_C_Fungi	167	179	PF08784	0.419
LIG_SH2_STAT3	159	162	PF00017	0.422
LIG_SH2_STAT5	159	162	PF00017	0.435
LIG_SH3_3	36	42	PF00018	0.609
LIG_SH3_3	44	50	PF00018	0.556
LIG_SH3_3	54	60	PF00018	0.475
LIG_SH3_3	61	67	PF00018	0.444
LIG_TRAF2_1	160	163	PF00917	0.420
LIG_TRAF2_1	291	294	PF00917	0.533
LIG_WW_2	64	67	PF00397	0.534
LIG_WW_3	130	134	PF00397	0.528
MOD_CDC14_SPxK_1	130	133	PF00782	0.529
MOD_CDK_SPK_2	117	122	PF00069	0.587
MOD_CDK_SPxK_1	117	123	PF00069	0.690
MOD_CDK_SPxK_1	127	133	PF00069	0.498
MOD_CK1_1	101	107	PF00069	0.580
MOD_CK1_1	237	243	PF00069	0.701
MOD_CK1_1	26	32	PF00069	0.686
MOD_CK1_1	265	271	PF00069	0.489
MOD_CK2_1	157	163	PF00069	0.406
MOD_CK2_1	272	278	PF00069	0.545
MOD_Cter_Amidation	297	300	PF01082	0.491
MOD_GlcNHglycan	239	242	PF01048	0.602
MOD_GlcNHglycan	243	246	PF01048	0.571
MOD_GlcNHglycan	25	28	PF01048	0.690
MOD_GlcNHglycan	251	254	PF01048	0.492
MOD_GlcNHglycan	264	267	PF01048	0.579
MOD_GlcNHglycan	278	281	PF01048	0.595
MOD_GSK3_1	100	107	PF00069	0.716
MOD_GSK3_1	16	23	PF00069	0.674
MOD_GSK3_1	235	242	PF00069	0.651
MOD_GSK3_1	249	256	PF00069	0.565
MOD_GSK3_1	272	279	PF00069	0.562
MOD_GSK3_1	29	36	PF00069	0.629
MOD_N-GLC_1	10	15	PF02516	0.560
MOD_NEK2_1	10	15	PF00069	0.588
MOD_NEK2_1	111	116	PF00069	0.569
MOD_NEK2_1	157	162	PF00069	0.423
MOD_NEK2_1	204	209	PF00069	0.566
MOD_NEK2_1	37	42	PF00069	0.623
MOD_NEK2_2	173	178	PF00069	0.400
MOD_PK_1	112	118	PF00069	0.490
MOD_PKA_1	262	268	PF00069	0.591
MOD_PKA_1	71	77	PF00069	0.507
MOD_PKA_2	111	117	PF00069	0.592
MOD_PKA_2	262	268	PF00069	0.591
MOD_PKA_2	276	282	PF00069	0.576
MOD_PKA_2	70	76	PF00069	0.536
MOD_Plk_1	10	16	PF00069	0.595
MOD_Plk_4	212	218	PF00069	0.503
MOD_ProDKin_1	117	123	PF00069	0.667
MOD_ProDKin_1	127	133	PF00069	0.498
MOD_ProDKin_1	31	37	PF00069	0.647
TRG_ENDOCYTIC_2	187	190	PF00928	0.499
TRG_ENDOCYTIC_2	243	246	PF00928	0.609
TRG_ER_diArg_1	125	128	PF00400	0.652
TRG_ER_diArg_1	170	172	PF00400	0.423
TRG_ER_diArg_1	230	232	PF00400	0.498
TRG_ER_diArg_1	295	297	PF00400	0.476
TRG_ER_diArg_1	70	72	PF00400	0.511
TRG_Pf-PMV_PEXEL_1	290	294	PF00026	0.572

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I5B4	Leptomonas seymouri	43%	100%
A0A3Q8ITS9	Leishmania donovani	84%	100%
A4HL48	Leishmania braziliensis	68%	100%
A4I8M7	Leishmania infantum	84%	100%