Mitochondrial RNA binding complex 1 subunit

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9B3H2_LEIMU

TriTrypDb:

LmxM.31.3940

Length:

555

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B3H2

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B3H2

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	340	344	PF00656	0.450
CLV_NRD_NRD_1	147	149	PF00675	0.516
CLV_NRD_NRD_1	417	419	PF00675	0.552
CLV_NRD_NRD_1	515	517	PF00675	0.366
CLV_NRD_NRD_1	99	101	PF00675	0.517
CLV_PCSK_KEX2_1	147	149	PF00082	0.484
CLV_PCSK_KEX2_1	515	517	PF00082	0.378
CLV_PCSK_KEX2_1	536	538	PF00082	0.444
CLV_PCSK_KEX2_1	87	89	PF00082	0.439
CLV_PCSK_KEX2_1	99	101	PF00082	0.424
CLV_PCSK_PC1ET2_1	536	538	PF00082	0.446
CLV_PCSK_PC1ET2_1	87	89	PF00082	0.371
CLV_PCSK_PC7_1	83	89	PF00082	0.270
CLV_PCSK_SKI1_1	117	121	PF00082	0.419
CLV_PCSK_SKI1_1	148	152	PF00082	0.505
CLV_PCSK_SKI1_1	161	165	PF00082	0.515
CLV_PCSK_SKI1_1	194	198	PF00082	0.535
CLV_PCSK_SKI1_1	418	422	PF00082	0.401
CLV_PCSK_SKI1_1	487	491	PF00082	0.474
CLV_PCSK_SKI1_1	528	532	PF00082	0.420
CLV_PCSK_SKI1_1	540	544	PF00082	0.257
CLV_PCSK_SKI1_1	83	87	PF00082	0.483
DEG_APCC_DBOX_1	147	155	PF00400	0.492
DEG_APCC_DBOX_1	160	168	PF00400	0.509
DEG_APCC_DBOX_1	527	535	PF00400	0.472
DEG_SCF_FBW7_1	74	80	PF00400	0.591
DOC_CDC14_PxL_1	448	456	PF14671	0.510
DOC_CKS1_1	74	79	PF01111	0.600
DOC_CYCLIN_RxL_1	362	371	PF00134	0.477
DOC_CYCLIN_yCln2_LP_2	303	309	PF00134	0.458
DOC_MAPK_DCC_7	172	180	PF00069	0.540
DOC_MAPK_gen_1	299	309	PF00069	0.550
DOC_MAPK_gen_1	536	547	PF00069	0.502
DOC_MAPK_MEF2A_6	540	549	PF00069	0.493
DOC_MAPK_RevD_3	404	419	PF00069	0.482
DOC_PP1_RVXF_1	416	423	PF00149	0.430
DOC_USP7_MATH_1	119	123	PF00917	0.536
DOC_USP7_MATH_1	206	210	PF00917	0.545
DOC_USP7_MATH_1	444	448	PF00917	0.497
DOC_USP7_MATH_1	77	81	PF00917	0.559
DOC_WW_Pin1_4	208	213	PF00397	0.465
DOC_WW_Pin1_4	302	307	PF00397	0.553
DOC_WW_Pin1_4	70	75	PF00397	0.608
DOC_WW_Pin1_4	8	13	PF00397	0.556
LIG_14-3-3_CanoR_1	19	24	PF00244	0.521
LIG_14-3-3_CanoR_1	198	204	PF00244	0.523
LIG_14-3-3_CanoR_1	424	429	PF00244	0.437
LIG_14-3-3_CanoR_1	474	479	PF00244	0.376
LIG_14-3-3_CanoR_1	516	522	PF00244	0.472
LIG_14-3-3_CanoR_1	540	549	PF00244	0.262
LIG_Actin_WH2_2	183	200	PF00022	0.508
LIG_Actin_WH2_2	471	489	PF00022	0.405
LIG_CaM_NSCaTE_8	228	235	PF13499	0.451
LIG_Clathr_ClatBox_1	352	356	PF01394	0.375
LIG_FHA_1	121	127	PF00498	0.559
LIG_FHA_1	348	354	PF00498	0.370
LIG_FHA_1	355	361	PF00498	0.347
LIG_FHA_1	389	395	PF00498	0.452
LIG_FHA_1	423	429	PF00498	0.286
LIG_FHA_1	486	492	PF00498	0.462
LIG_FHA_2	219	225	PF00498	0.447
LIG_FHA_2	242	248	PF00498	0.501
LIG_FHA_2	396	402	PF00498	0.403
LIG_FHA_2	42	48	PF00498	0.446
LIG_FHA_2	497	503	PF00498	0.508
LIG_HCF-1_HBM_1	371	374	PF13415	0.516
LIG_LIR_Gen_1	22	30	PF02991	0.410
LIG_LIR_Gen_1	253	263	PF02991	0.436
LIG_LIR_Gen_1	266	276	PF02991	0.462
LIG_LIR_Gen_1	308	318	PF02991	0.481
LIG_LIR_Gen_1	371	382	PF02991	0.476
LIG_LIR_Nem_3	22	26	PF02991	0.418
LIG_LIR_Nem_3	253	258	PF02991	0.432
LIG_LIR_Nem_3	266	271	PF02991	0.414
LIG_LIR_Nem_3	308	313	PF02991	0.448
LIG_LIR_Nem_3	371	376	PF02991	0.444
LIG_LIR_Nem_3	62	68	PF02991	0.443
LIG_LYPXL_yS_3	381	384	PF13949	0.388
LIG_MYND_1	551	555	PF01753	0.598
LIG_NRBOX	130	136	PF00104	0.538
LIG_NRBOX	505	511	PF00104	0.487
LIG_PCNA_PIPBox_1	367	376	PF02747	0.550
LIG_PCNA_yPIPBox_3	249	263	PF02747	0.460
LIG_PCNA_yPIPBox_3	365	374	PF02747	0.439
LIG_SH2_CRK	255	259	PF00017	0.418
LIG_SH2_CRK	65	69	PF00017	0.438
LIG_SH2_SRC	36	39	PF00017	0.397
LIG_SH2_STAP1	263	267	PF00017	0.489
LIG_SH2_STAP1	324	328	PF00017	0.464
LIG_SH2_STAP1	334	338	PF00017	0.503
LIG_SH2_STAT3	376	379	PF00017	0.544
LIG_SH2_STAT5	36	39	PF00017	0.585
LIG_SH2_STAT5	435	438	PF00017	0.504
LIG_SH2_STAT5	485	488	PF00017	0.411
LIG_SH2_STAT5	517	520	PF00017	0.528
LIG_SH3_2	74	79	PF14604	0.545
LIG_SH3_3	37	43	PF00018	0.489
LIG_SH3_3	389	395	PF00018	0.439
LIG_SH3_3	71	77	PF00018	0.526
LIG_SUMO_SIM_anti_2	350	357	PF11976	0.345
LIG_SUMO_SIM_anti_2	425	430	PF11976	0.277
LIG_SUMO_SIM_par_1	211	216	PF11976	0.414
LIG_SUMO_SIM_par_1	350	357	PF11976	0.345
LIG_TRAF2_1	221	224	PF00917	0.474
LIG_TYR_ITIM	63	68	PF00017	0.409
LIG_UBA3_1	218	227	PF00899	0.488
LIG_UBA3_1	359	366	PF00899	0.494
LIG_UBA3_1	506	511	PF00899	0.382
LIG_UBA3_1	530	536	PF00899	0.403
LIG_UBA3_1	63	69	PF00899	0.268
MOD_CDK_SPxK_1	73	79	PF00069	0.630
MOD_CK1_1	337	343	PF00069	0.535
MOD_CK1_1	73	79	PF00069	0.466
MOD_CK1_1	94	100	PF00069	0.513
MOD_CK2_1	218	224	PF00069	0.469
MOD_CK2_1	241	247	PF00069	0.479
MOD_CK2_1	395	401	PF00069	0.404
MOD_CK2_1	41	47	PF00069	0.469
MOD_CK2_1	496	502	PF00069	0.514
MOD_DYRK1A_RPxSP_1	8	12	PF00069	0.530
MOD_GlcNHglycan	107	110	PF01048	0.567
MOD_GlcNHglycan	194	197	PF01048	0.487
MOD_GlcNHglycan	215	218	PF01048	0.381
MOD_GlcNHglycan	241	244	PF01048	0.552
MOD_GlcNHglycan	343	346	PF01048	0.519
MOD_GlcNHglycan	59	62	PF01048	0.311
MOD_GSK3_1	15	22	PF00069	0.398
MOD_GSK3_1	150	157	PF00069	0.457
MOD_GSK3_1	218	225	PF00069	0.431
MOD_GSK3_1	318	325	PF00069	0.441
MOD_GSK3_1	337	344	PF00069	0.201
MOD_GSK3_1	420	427	PF00069	0.401
MOD_GSK3_1	474	481	PF00069	0.445
MOD_GSK3_1	485	492	PF00069	0.425
MOD_GSK3_1	536	543	PF00069	0.437
MOD_GSK3_1	55	62	PF00069	0.439
MOD_GSK3_1	73	80	PF00069	0.543
MOD_N-GLC_1	250	255	PF02516	0.558
MOD_NEK2_1	120	125	PF00069	0.552
MOD_NEK2_1	140	145	PF00069	0.230
MOD_NEK2_1	15	20	PF00069	0.422
MOD_NEK2_1	197	202	PF00069	0.480
MOD_NEK2_1	213	218	PF00069	0.223
MOD_NEK2_1	222	227	PF00069	0.466
MOD_NEK2_1	241	246	PF00069	0.247
MOD_NEK2_1	318	323	PF00069	0.442
MOD_NEK2_1	341	346	PF00069	0.400
MOD_NEK2_1	420	425	PF00069	0.359
MOD_NEK2_1	495	500	PF00069	0.578
MOD_NEK2_2	319	324	PF00069	0.440
MOD_NEK2_2	517	522	PF00069	0.528
MOD_PIKK_1	540	546	PF00454	0.247
MOD_PIKK_1	55	61	PF00454	0.443
MOD_PK_1	474	480	PF00069	0.479
MOD_PKA_1	536	542	PF00069	0.405
MOD_PKA_2	197	203	PF00069	0.545
MOD_PKA_2	293	299	PF00069	0.663
MOD_PKA_2	536	542	PF00069	0.405
MOD_Plk_1	141	147	PF00069	0.520
MOD_Plk_1	250	256	PF00069	0.554
MOD_Plk_1	77	83	PF00069	0.560
MOD_Plk_4	130	136	PF00069	0.500
MOD_Plk_4	250	256	PF00069	0.525
MOD_Plk_4	312	318	PF00069	0.481
MOD_Plk_4	319	325	PF00069	0.414
MOD_Plk_4	337	343	PF00069	0.341
MOD_Plk_4	388	394	PF00069	0.483
MOD_Plk_4	424	430	PF00069	0.387
MOD_Plk_4	59	65	PF00069	0.335
MOD_Plk_4	77	83	PF00069	0.456
MOD_ProDKin_1	208	214	PF00069	0.459
MOD_ProDKin_1	302	308	PF00069	0.554
MOD_ProDKin_1	70	76	PF00069	0.606
MOD_ProDKin_1	8	14	PF00069	0.556
TRG_DiLeu_BaLyEn_6	136	141	PF01217	0.460
TRG_DiLeu_BaLyEn_6	209	214	PF01217	0.530
TRG_DiLeu_BaLyEn_6	525	530	PF01217	0.472
TRG_ENDOCYTIC_2	255	258	PF00928	0.414
TRG_ENDOCYTIC_2	268	271	PF00928	0.378
TRG_ENDOCYTIC_2	374	377	PF00928	0.400
TRG_ENDOCYTIC_2	381	384	PF00928	0.375
TRG_ENDOCYTIC_2	456	459	PF00928	0.409
TRG_ENDOCYTIC_2	65	68	PF00928	0.409
TRG_ER_diArg_1	147	149	PF00400	0.521
TRG_ER_diArg_1	283	286	PF00400	0.607
TRG_ER_diArg_1	514	516	PF00400	0.364
TRG_ER_diArg_1	98	100	PF00400	0.567
TRG_Pf-PMV_PEXEL_1	100	104	PF00026	0.554
TRG_Pf-PMV_PEXEL_1	287	291	PF00026	0.674

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1II47	Leptomonas seymouri	58%	100%
A0A0S4JG92	Bodo saltans	23%	76%
A0A1X0NRZ6	Trypanosomatidae	39%	99%
A0A3Q8IGL6	Leishmania donovani	92%	100%
A0A422NHU1	Trypanosoma rangeli	41%	98%
A4HL31	Leishmania braziliensis	80%	100%
A4I8L2	Leishmania infantum	91%	100%
D0AAK3	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	38%	92%
Q4Q4M8	Leishmania major	92%	100%
V5BI03	Trypanosoma cruzi	41%	98%