Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania mexicana

UniProt:

E9B3G3_LEIMU

TriTrypDb:

LmxM.31.3850

Length:

291

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B3G3

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B3G3

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	132	136	PF00656	0.572
CLV_C14_Caspase3-7	225	229	PF00656	0.591
CLV_NRD_NRD_1	120	122	PF00675	0.476
CLV_NRD_NRD_1	232	234	PF00675	0.508
CLV_NRD_NRD_1	34	36	PF00675	0.683
CLV_NRD_NRD_1	82	84	PF00675	0.679
CLV_PCSK_FUR_1	80	84	PF00082	0.678
CLV_PCSK_KEX2_1	232	234	PF00082	0.619
CLV_PCSK_KEX2_1	283	285	PF00082	0.779
CLV_PCSK_KEX2_1	34	36	PF00082	0.683
CLV_PCSK_KEX2_1	82	84	PF00082	0.679
CLV_PCSK_PC1ET2_1	283	285	PF00082	0.808
CLV_PCSK_SKI1_1	121	125	PF00082	0.665
CLV_PCSK_SKI1_1	83	87	PF00082	0.677
CLV_Separin_Metazoa	180	184	PF03568	0.582
DEG_Nend_UBRbox_1	1	4	PF02207	0.729
DOC_USP7_MATH_1	231	235	PF00917	0.689
DOC_USP7_MATH_1	38	42	PF00917	0.682
DOC_USP7_MATH_1	4	8	PF00917	0.676
DOC_USP7_MATH_1	9	13	PF00917	0.611
DOC_WW_Pin1_4	171	176	PF00397	0.467
DOC_WW_Pin1_4	268	273	PF00397	0.737
LIG_Actin_WH2_2	106	123	PF00022	0.451
LIG_Actin_WH2_2	153	170	PF00022	0.510
LIG_Actin_WH2_2	71	89	PF00022	0.676
LIG_BIR_III_2	135	139	PF00653	0.593
LIG_FHA_1	172	178	PF00498	0.431
LIG_FHA_1	190	196	PF00498	0.679
LIG_FHA_2	23	29	PF00498	0.713
LIG_LIR_Gen_1	249	255	PF02991	0.563
LIG_LIR_Gen_1	271	280	PF02991	0.710
LIG_LIR_Nem_3	249	253	PF02991	0.597
LIG_LIR_Nem_3	271	276	PF02991	0.662
LIG_Rb_LxCxE_1	234	252	PF01857	0.450
LIG_SH2_STAT5	208	211	PF00017	0.650
LIG_SH3_3	135	141	PF00018	0.794
LIG_TRAF2_1	129	132	PF00917	0.589
LIG_TRAF2_1	169	172	PF00917	0.688
LIG_WRC_WIRS_1	247	252	PF05994	0.589
MOD_CK1_1	249	255	PF00069	0.784
MOD_CK1_1	257	263	PF00069	0.689
MOD_CK1_1	53	59	PF00069	0.600
MOD_CK1_1	7	13	PF00069	0.497
MOD_CK2_1	126	132	PF00069	0.644
MOD_CK2_1	156	162	PF00069	0.702
MOD_CK2_1	53	59	PF00069	0.719
MOD_CK2_1	95	101	PF00069	0.382
MOD_GlcNHglycan	11	14	PF01048	0.645
MOD_GlcNHglycan	128	131	PF01048	0.648
MOD_GlcNHglycan	153	156	PF01048	0.521
MOD_GlcNHglycan	257	260	PF01048	0.810
MOD_GlcNHglycan	6	9	PF01048	0.713
MOD_GlcNHglycan	87	90	PF01048	0.680
MOD_GSK3_1	260	267	PF00069	0.815
MOD_GSK3_1	43	50	PF00069	0.773
MOD_N-GLC_1	265	270	PF02516	0.653
MOD_NEK2_1	126	131	PF00069	0.636
MOD_NEK2_1	85	90	PF00069	0.678
MOD_NEK2_1	95	100	PF00069	0.510
MOD_PIKK_1	189	195	PF00454	0.678
MOD_PIKK_1	257	263	PF00454	0.743
MOD_PIKK_1	43	49	PF00454	0.720
MOD_PIKK_1	95	101	PF00454	0.596
MOD_PKA_2	231	237	PF00069	0.697
MOD_Plk_4	204	210	PF00069	0.364
MOD_Plk_4	246	252	PF00069	0.657
MOD_ProDKin_1	171	177	PF00069	0.463
MOD_ProDKin_1	268	274	PF00069	0.736
MOD_SUMO_rev_2	162	170	PF00179	0.557
TRG_ER_diArg_1	102	105	PF00400	0.609
TRG_ER_diArg_1	182	185	PF00400	0.589
TRG_NES_CRM1_1	242	255	PF08389	0.693
TRG_Pf-PMV_PEXEL_1	121	125	PF00026	0.471
TRG_Pf-PMV_PEXEL_1	158	162	PF00026	0.720

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3Q8IEK8	Leishmania donovani	84%	100%
A4HL22	Leishmania braziliensis	58%	100%
A4I8K3	Leishmania infantum	85%	100%
Q4Q4N7	Leishmania major	82%	100%