Putative kinetoplast-associated protein p18-2

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

kinetoplast-associated protein p18-2, putative

Species:

Leishmania mexicana

UniProt:

E9B3F5_LEIMU

TriTrypDb:

LmxM.31.3770

Length:

132

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B3F5

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B3F5

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	3	5	PF00675	0.679
CLV_NRD_NRD_1	42	44	PF00675	0.453
CLV_NRD_NRD_1	54	56	PF00675	0.500
CLV_NRD_NRD_1	98	100	PF00675	0.599
CLV_PCSK_KEX2_1	3	5	PF00082	0.679
CLV_PCSK_KEX2_1	42	44	PF00082	0.420
CLV_PCSK_KEX2_1	54	56	PF00082	0.521
CLV_PCSK_KEX2_1	72	74	PF00082	0.537
CLV_PCSK_KEX2_1	76	78	PF00082	0.482
CLV_PCSK_KEX2_1	85	87	PF00082	0.384
CLV_PCSK_KEX2_1	98	100	PF00082	0.567
CLV_PCSK_PC1ET2_1	72	74	PF00082	0.582
CLV_PCSK_PC1ET2_1	76	78	PF00082	0.527
CLV_PCSK_PC1ET2_1	85	87	PF00082	0.384
CLV_PCSK_SKI1_1	125	129	PF00082	0.669
CLV_PCSK_SKI1_1	28	32	PF00082	0.590
CLV_PCSK_SKI1_1	54	58	PF00082	0.544
CLV_PCSK_SKI1_1	69	73	PF00082	0.314
CLV_Separin_Metazoa	7	11	PF03568	0.443
DEG_Nend_Nbox_1	1	3	PF02207	0.763
DOC_MAPK_gen_1	3	11	PF00069	0.572
DOC_USP7_MATH_1	47	51	PF00917	0.509
DOC_USP7_UBL2_3	113	117	PF12436	0.597
DOC_USP7_UBL2_3	121	125	PF12436	0.565
DOC_USP7_UBL2_3	128	132	PF12436	0.692
DOC_USP7_UBL2_3	72	76	PF12436	0.415
DOC_WW_Pin1_4	42	47	PF00397	0.633
DOC_WW_Pin1_4	9	14	PF00397	0.625
LIG_14-3-3_CanoR_1	3	11	PF00244	0.493
LIG_Actin_WH2_2	14	30	PF00022	0.493
LIG_CaM_IQ_9	15	30	PF13499	0.495
LIG_FHA_1	104	110	PF00498	0.562
LIG_FHA_1	22	28	PF00498	0.545
LIG_FHA_1	58	64	PF00498	0.479
LIG_LIR_Gen_1	12	21	PF02991	0.530
LIG_LIR_Nem_3	12	17	PF02991	0.473
LIG_SH2_CRK	41	45	PF00017	0.525
MOD_CDK_SPxxK_3	42	49	PF00069	0.633
MOD_CK1_1	100	106	PF00069	0.612
MOD_CK2_1	42	48	PF00069	0.637
MOD_Cter_Amidation	122	125	PF01082	0.630
MOD_GlcNHglycan	110	113	PF01048	0.718
MOD_GlcNHglycan	48	52	PF01048	0.497
MOD_GSK3_1	103	110	PF00069	0.596
MOD_GSK3_1	93	100	PF00069	0.535
MOD_N-GLC_2	32	34	PF02516	0.515
MOD_NEK2_1	97	102	PF00069	0.634
MOD_PIKK_1	2	8	PF00454	0.492
MOD_PKA_2	2	8	PF00069	0.667
MOD_PKA_2	97	103	PF00069	0.579
MOD_Plk_1	47	53	PF00069	0.537
MOD_Plk_1	57	63	PF00069	0.503
MOD_ProDKin_1	42	48	PF00069	0.634
MOD_ProDKin_1	9	15	PF00069	0.624
MOD_SUMO_for_1	71	74	PF00179	0.476
TRG_ENDOCYTIC_2	41	44	PF00928	0.623
TRG_ENDOCYTIC_2	67	70	PF00928	0.616
TRG_ER_diArg_1	2	4	PF00400	0.693
TRG_ER_diArg_1	41	43	PF00400	0.411
TRG_ER_diArg_1	53	55	PF00400	0.424
TRG_ER_diArg_1	97	99	PF00400	0.590
TRG_NES_CRM1_1	74	87	PF08389	0.442

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IIB3	Leptomonas seymouri	32%	100%
A0A1X0NSD7	Trypanosomatidae	31%	73%
A0A3Q8IGK7	Leishmania donovani	81%	100%
A0A3Q8ITR1	Leishmania donovani	39%	97%
A0A422P329	Trypanosoma rangeli	33%	69%
A4HL14	Leishmania braziliensis	61%	100%
A4HL15	Leishmania braziliensis	43%	100%
A4I8J5	Leishmania infantum	81%	100%
A4I8J6	Leishmania infantum	39%	97%
E9B3F6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	40%	100%
Q4Q4P4	Leishmania major	41%	100%
Q4Q4P5	Leishmania major	84%	100%
Q8IS98	Crithidia fasciculata	37%	99%
Q9TY83	Crithidia fasciculata	41%	100%
Q9TY84	Crithidia fasciculata	41%	100%