Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9B3F2_LEIMU

TriTrypDb:

LmxM.31.3740

Length:

155

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B3F2

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B3F2

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_PCSK_KEX2_1	128	130	PF00082	0.507
CLV_PCSK_PC1ET2_1	128	130	PF00082	0.493
CLV_PCSK_SKI1_1	14	18	PF00082	0.348
DEG_SPOP_SBC_1	149	153	PF00917	0.415
DOC_CKS1_1	79	84	PF01111	0.500
DOC_MAPK_gen_1	61	69	PF00069	0.426
DOC_PP2B_LxvP_1	67	70	PF13499	0.546
DOC_WW_Pin1_4	54	59	PF00397	0.464
DOC_WW_Pin1_4	75	80	PF00397	0.492
LIG_14-3-3_CanoR_1	110	118	PF00244	0.584
LIG_14-3-3_CanoR_1	137	142	PF00244	0.456
LIG_14-3-3_CanoR_1	14	19	PF00244	0.358
LIG_BIR_II_1	1	5	PF00653	0.498
LIG_BRCT_BRCA1_1	139	143	PF00533	0.461
LIG_CSL_BTD_1	79	82	PF09270	0.487
LIG_DLG_GKlike_1	137	145	PF00625	0.465
LIG_FHA_1	110	116	PF00498	0.458
LIG_Integrin_isoDGR_2	104	106	PF01839	0.534
LIG_LIR_Gen_1	2	11	PF02991	0.445
LIG_LIR_Gen_1	38	46	PF02991	0.527
LIG_LIR_Gen_1	96	107	PF02991	0.421
LIG_LIR_Nem_3	15	21	PF02991	0.340
LIG_LIR_Nem_3	2	7	PF02991	0.454
LIG_LIR_Nem_3	38	44	PF02991	0.560
LIG_LIR_Nem_3	55	59	PF02991	0.488
LIG_LIR_Nem_3	71	77	PF02991	0.394
LIG_LIR_Nem_3	96	102	PF02991	0.409
LIG_PTB_Apo_2	101	108	PF02174	0.499
LIG_SH2_CRK	21	25	PF00017	0.442
LIG_SH2_GRB2like	74	77	PF00017	0.607
LIG_SH2_STAT5	36	39	PF00017	0.538
LIG_SH2_STAT5	52	55	PF00017	0.411
LIG_SH2_STAT5	74	77	PF00017	0.519
LIG_SH2_STAT5	99	102	PF00017	0.540
LIG_SH3_3	76	82	PF00018	0.491
LIG_SH3_4	61	68	PF00018	0.562
LIG_SUMO_SIM_par_1	65	71	PF11976	0.416
LIG_TRAF2_1	120	123	PF00917	0.453
MOD_CDK_SPK_2	78	83	PF00069	0.518
MOD_CDK_SPxxK_3	54	61	PF00069	0.475
MOD_CK1_1	3	9	PF00069	0.423
MOD_CK1_1	78	84	PF00069	0.546
MOD_CK2_1	124	130	PF00069	0.459
MOD_GSK3_1	10	17	PF00069	0.391
MOD_GSK3_1	109	116	PF00069	0.511
MOD_GSK3_1	137	144	PF00069	0.567
MOD_GSK3_1	145	152	PF00069	0.628
MOD_GSK3_1	68	75	PF00069	0.344
MOD_LATS_1	12	18	PF00433	0.317
MOD_LATS_1	135	141	PF00433	0.320
MOD_N-GLC_1	75	80	PF02516	0.511
MOD_NEK2_1	10	15	PF00069	0.490
MOD_PKA_2	109	115	PF00069	0.479
MOD_PKA_2	149	155	PF00069	0.466
MOD_PKA_2	72	78	PF00069	0.378
MOD_Plk_4	113	119	PF00069	0.595
MOD_Plk_4	137	143	PF00069	0.460
MOD_ProDKin_1	54	60	PF00069	0.472
MOD_ProDKin_1	75	81	PF00069	0.493
TRG_DiLeu_BaLyEn_6	134	139	PF01217	0.449
TRG_ENDOCYTIC_2	21	24	PF00928	0.392
TRG_ENDOCYTIC_2	41	44	PF00928	0.507
TRG_ENDOCYTIC_2	99	102	PF00928	0.552
TRG_Pf-PMV_PEXEL_1	119	123	PF00026	0.510

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P3W3	Leptomonas seymouri	81%	100%
A0A1X0NRY2	Trypanosomatidae	69%	100%
A0A3Q8IGB2	Leishmania donovani	88%	100%
A0A3R7N368	Trypanosoma rangeli	60%	100%
A4HL11	Leishmania braziliensis	85%	100%
A4I8J2	Leishmania infantum	88%	100%
D0AAM6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	68%	100%
Q4Q4P8	Leishmania major	89%	100%
V5DME5	Trypanosoma cruzi	65%	100%