Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9B3E7_LEIMU

TriTrypDb:

LmxM.31.3690

Length:

967

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 4
NetGPI	no	yes: 0, no: 4

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B3E7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B3E7

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	214	218	PF00656	0.619
CLV_C14_Caspase3-7	24	28	PF00656	0.545
CLV_NRD_NRD_1	135	137	PF00675	0.660
CLV_NRD_NRD_1	147	149	PF00675	0.546
CLV_NRD_NRD_1	247	249	PF00675	0.663
CLV_NRD_NRD_1	29	31	PF00675	0.688
CLV_NRD_NRD_1	381	383	PF00675	0.623
CLV_NRD_NRD_1	517	519	PF00675	0.626
CLV_NRD_NRD_1	547	549	PF00675	0.674
CLV_NRD_NRD_1	601	603	PF00675	0.659
CLV_NRD_NRD_1	646	648	PF00675	0.509
CLV_NRD_NRD_1	65	67	PF00675	0.653
CLV_NRD_NRD_1	658	660	PF00675	0.418
CLV_NRD_NRD_1	720	722	PF00675	0.698
CLV_NRD_NRD_1	822	824	PF00675	0.671
CLV_NRD_NRD_1	843	845	PF00675	0.671
CLV_NRD_NRD_1	92	94	PF00675	0.530
CLV_NRD_NRD_1	961	963	PF00675	0.477
CLV_PCSK_FUR_1	132	136	PF00082	0.663
CLV_PCSK_FUR_1	63	67	PF00082	0.657
CLV_PCSK_KEX2_1	132	134	PF00082	0.659
CLV_PCSK_KEX2_1	135	137	PF00082	0.636
CLV_PCSK_KEX2_1	147	149	PF00082	0.522
CLV_PCSK_KEX2_1	240	242	PF00082	0.649
CLV_PCSK_KEX2_1	247	249	PF00082	0.618
CLV_PCSK_KEX2_1	381	383	PF00082	0.623
CLV_PCSK_KEX2_1	549	551	PF00082	0.613
CLV_PCSK_KEX2_1	63	65	PF00082	0.660
CLV_PCSK_KEX2_1	646	648	PF00082	0.509
CLV_PCSK_KEX2_1	720	722	PF00082	0.691
CLV_PCSK_KEX2_1	733	735	PF00082	0.562
CLV_PCSK_KEX2_1	92	94	PF00082	0.530
CLV_PCSK_KEX2_1	961	963	PF00082	0.477
CLV_PCSK_PC1ET2_1	240	242	PF00082	0.649
CLV_PCSK_PC1ET2_1	549	551	PF00082	0.613
CLV_PCSK_PC1ET2_1	733	735	PF00082	0.675
CLV_PCSK_PC7_1	60	66	PF00082	0.657
CLV_PCSK_PC7_1	729	735	PF00082	0.674
CLV_PCSK_SKI1_1	486	490	PF00082	0.558
CLV_PCSK_SKI1_1	511	515	PF00082	0.546
CLV_PCSK_SKI1_1	550	554	PF00082	0.613
CLV_PCSK_SKI1_1	734	738	PF00082	0.688
CLV_Separin_Metazoa	649	653	PF03568	0.509
DEG_APCC_DBOX_1	665	673	PF00400	0.453
DEG_SPOP_SBC_1	411	415	PF00917	0.668
DEG_SPOP_SBC_1	703	707	PF00917	0.684
DOC_CKS1_1	286	291	PF01111	0.525
DOC_CKS1_1	451	456	PF01111	0.620
DOC_CYCLIN_RxL_1	932	942	PF00134	0.474
DOC_PP1_RVXF_1	484	490	PF00149	0.682
DOC_PP2B_LxvP_1	224	227	PF13499	0.545
DOC_PP2B_LxvP_1	539	542	PF13499	0.663
DOC_PP4_FxxP_1	317	320	PF00568	0.660
DOC_USP7_MATH_1	127	131	PF00917	0.663
DOC_USP7_MATH_1	140	144	PF00917	0.542
DOC_USP7_MATH_1	175	179	PF00917	0.689
DOC_USP7_MATH_1	276	280	PF00917	0.621
DOC_USP7_MATH_1	297	301	PF00917	0.559
DOC_USP7_MATH_1	334	338	PF00917	0.684
DOC_USP7_MATH_1	347	351	PF00917	0.570
DOC_USP7_MATH_1	353	357	PF00917	0.522
DOC_USP7_MATH_1	359	363	PF00917	0.553
DOC_USP7_MATH_1	36	40	PF00917	0.598
DOC_USP7_MATH_1	383	387	PF00917	0.674
DOC_USP7_MATH_1	476	480	PF00917	0.677
DOC_USP7_MATH_1	481	485	PF00917	0.641
DOC_USP7_MATH_1	521	525	PF00917	0.672
DOC_USP7_MATH_1	703	707	PF00917	0.595
DOC_USP7_MATH_1	764	768	PF00917	0.627
DOC_USP7_MATH_1	773	777	PF00917	0.642
DOC_USP7_MATH_1	850	854	PF00917	0.611
DOC_USP7_MATH_1	902	906	PF00917	0.594
DOC_USP7_UBL2_3	466	470	PF12436	0.546
DOC_WW_Pin1_4	10	15	PF00397	0.635
DOC_WW_Pin1_4	159	164	PF00397	0.513
DOC_WW_Pin1_4	204	209	PF00397	0.672
DOC_WW_Pin1_4	285	290	PF00397	0.602
DOC_WW_Pin1_4	3	8	PF00397	0.707
DOC_WW_Pin1_4	302	307	PF00397	0.551
DOC_WW_Pin1_4	316	321	PF00397	0.645
DOC_WW_Pin1_4	32	37	PF00397	0.671
DOC_WW_Pin1_4	332	337	PF00397	0.555
DOC_WW_Pin1_4	357	362	PF00397	0.662
DOC_WW_Pin1_4	381	386	PF00397	0.679
DOC_WW_Pin1_4	412	417	PF00397	0.599
DOC_WW_Pin1_4	420	425	PF00397	0.646
DOC_WW_Pin1_4	429	434	PF00397	0.588
DOC_WW_Pin1_4	435	440	PF00397	0.551
DOC_WW_Pin1_4	450	455	PF00397	0.563
DOC_WW_Pin1_4	492	497	PF00397	0.674
DOC_WW_Pin1_4	704	709	PF00397	0.674
DOC_WW_Pin1_4	736	741	PF00397	0.762
DOC_WW_Pin1_4	790	795	PF00397	0.667
DOC_WW_Pin1_4	854	859	PF00397	0.591
DOC_WW_Pin1_4	874	879	PF00397	0.571
LIG_14-3-3_CanoR_1	147	155	PF00244	0.577
LIG_14-3-3_CanoR_1	203	208	PF00244	0.677
LIG_14-3-3_CanoR_1	247	252	PF00244	0.605
LIG_14-3-3_CanoR_1	30	36	PF00244	0.677
LIG_14-3-3_CanoR_1	401	410	PF00244	0.650
LIG_14-3-3_CanoR_1	511	516	PF00244	0.685
LIG_14-3-3_CanoR_1	53	62	PF00244	0.647
LIG_14-3-3_CanoR_1	548	553	PF00244	0.625
LIG_14-3-3_CanoR_1	575	582	PF00244	0.606
LIG_14-3-3_CanoR_1	593	599	PF00244	0.614
LIG_14-3-3_CanoR_1	600	610	PF00244	0.668
LIG_14-3-3_CanoR_1	638	642	PF00244	0.450
LIG_14-3-3_CanoR_1	704	708	PF00244	0.674
LIG_14-3-3_CanoR_1	720	728	PF00244	0.560
LIG_14-3-3_CanoR_1	753	762	PF00244	0.611
LIG_14-3-3_CanoR_1	780	786	PF00244	0.665
LIG_14-3-3_CanoR_1	809	814	PF00244	0.638
LIG_BIR_II_1	1	5	PF00653	0.652
LIG_BIR_III_2	309	313	PF00653	0.499
LIG_BRCT_BRCA1_1	785	789	PF00533	0.543
LIG_deltaCOP1_diTrp_1	80	85	PF00928	0.557
LIG_FHA_1	108	114	PF00498	0.664
LIG_FHA_1	160	166	PF00498	0.520
LIG_FHA_1	230	236	PF00498	0.659
LIG_FHA_1	50	56	PF00498	0.641
LIG_FHA_1	524	530	PF00498	0.645
LIG_FHA_1	628	634	PF00498	0.614
LIG_FHA_1	637	643	PF00498	0.473
LIG_FHA_1	826	832	PF00498	0.605
LIG_FHA_1	883	889	PF00498	0.668
LIG_FHA_1	901	907	PF00498	0.513
LIG_FHA_1	911	917	PF00498	0.576
LIG_FHA_2	241	247	PF00498	0.539
LIG_FHA_2	286	292	PF00498	0.524
LIG_FHA_2	526	532	PF00498	0.573
LIG_Integrin_RGD_1	104	106	PF01839	0.652
LIG_LIR_Apic_2	279	283	PF02991	0.509
LIG_LIR_Gen_1	816	826	PF02991	0.586
LIG_LIR_Gen_1	82	91	PF02991	0.530
LIG_LIR_Nem_3	816	822	PF02991	0.589
LIG_LIR_Nem_3	82	88	PF02991	0.536
LIG_MYND_1	500	504	PF01753	0.661
LIG_PCNA_yPIPBox_3	777	789	PF02747	0.607
LIG_PDZ_Class_2	962	967	PF00595	0.519
LIG_Pex14_1	81	85	PF04695	0.554
LIG_SH2_CRK	11	15	PF00017	0.626
LIG_SH2_NCK_1	213	217	PF00017	0.622
LIG_SH2_STAT5	964	967	PF00017	0.548
LIG_SH3_2	728	733	PF14604	0.595
LIG_SH3_3	270	276	PF00018	0.658
LIG_SH3_3	278	284	PF00018	0.581
LIG_SH3_3	436	442	PF00018	0.600
LIG_SH3_3	448	454	PF00018	0.594
LIG_SH3_3	526	532	PF00018	0.628
LIG_SH3_3	539	545	PF00018	0.604
LIG_SH3_3	616	622	PF00018	0.593
LIG_SH3_3	722	728	PF00018	0.686
LIG_SH3_4	466	473	PF00018	0.543
LIG_TRAF2_1	199	202	PF00917	0.687
LIG_TRAF2_1	243	246	PF00917	0.663
MOD_CDC14_SPxK_1	335	338	PF00782	0.685
MOD_CDC14_SPxK_1	35	38	PF00782	0.661
MOD_CDK_SPxK_1	32	38	PF00069	0.670
MOD_CDK_SPxK_1	332	338	PF00069	0.687
MOD_CDK_SPxK_1	422	428	PF00069	0.653
MOD_CDK_SPxK_1	450	456	PF00069	0.685
MOD_CDK_SPxxK_3	285	292	PF00069	0.525
MOD_CDK_SPxxK_3	316	323	PF00069	0.663
MOD_CDK_SPxxK_3	492	499	PF00069	0.672
MOD_CK1_1	123	129	PF00069	0.667
MOD_CK1_1	151	157	PF00069	0.566
MOD_CK1_1	2	8	PF00069	0.655
MOD_CK1_1	20	26	PF00069	0.674
MOD_CK1_1	207	213	PF00069	0.571
MOD_CK1_1	301	307	PF00069	0.671
MOD_CK1_1	32	38	PF00069	0.573
MOD_CK1_1	337	343	PF00069	0.614
MOD_CK1_1	360	366	PF00069	0.614
MOD_CK1_1	384	390	PF00069	0.656
MOD_CK1_1	391	397	PF00069	0.650
MOD_CK1_1	455	461	PF00069	0.680
MOD_CK1_1	524	530	PF00069	0.545
MOD_CK1_1	54	60	PF00069	0.646
MOD_CK1_1	574	580	PF00069	0.606
MOD_CK1_1	605	611	PF00069	0.499
MOD_CK1_1	723	729	PF00069	0.574
MOD_CK1_1	784	790	PF00069	0.659
MOD_CK1_1	836	842	PF00069	0.542
MOD_CK1_1	857	863	PF00069	0.593
MOD_CK1_1	882	888	PF00069	0.669
MOD_CK1_1	919	925	PF00069	0.601
MOD_CK2_1	118	124	PF00069	0.674
MOD_CK2_1	181	187	PF00069	0.695
MOD_CK2_1	240	246	PF00069	0.533
MOD_CK2_1	269	275	PF00069	0.526
MOD_CK2_1	285	291	PF00069	0.506
MOD_CK2_1	525	531	PF00069	0.580
MOD_CK2_1	789	795	PF00069	0.608
MOD_Cter_Amidation	145	148	PF01082	0.510
MOD_Cter_Amidation	28	31	PF01082	0.685
MOD_Cter_Amidation	718	721	PF01082	0.634
MOD_DYRK1A_RPxSP_1	704	708	PF00069	0.674
MOD_GlcNHglycan	124	128	PF01048	0.666
MOD_GlcNHglycan	142	145	PF01048	0.501
MOD_GlcNHglycan	159	162	PF01048	0.514
MOD_GlcNHglycan	176	180	PF01048	0.554
MOD_GlcNHglycan	183	186	PF01048	0.638
MOD_GlcNHglycan	196	199	PF01048	0.523
MOD_GlcNHglycan	214	217	PF01048	0.537
MOD_GlcNHglycan	232	235	PF01048	0.515
MOD_GlcNHglycan	254	257	PF01048	0.661
MOD_GlcNHglycan	349	352	PF01048	0.679
MOD_GlcNHglycan	387	390	PF01048	0.692
MOD_GlcNHglycan	393	396	PF01048	0.627
MOD_GlcNHglycan	457	460	PF01048	0.678
MOD_GlcNHglycan	478	481	PF01048	0.679
MOD_GlcNHglycan	558	561	PF01048	0.679
MOD_GlcNHglycan	576	579	PF01048	0.519
MOD_GlcNHglycan	589	592	PF01048	0.592
MOD_GlcNHglycan	623	626	PF01048	0.576
MOD_GlcNHglycan	682	685	PF01048	0.621
MOD_GlcNHglycan	69	73	PF01048	0.727
MOD_GlcNHglycan	699	702	PF01048	0.537
MOD_GlcNHglycan	722	725	PF01048	0.579
MOD_GlcNHglycan	744	747	PF01048	0.516
MOD_GlcNHglycan	831	834	PF01048	0.642
MOD_GlcNHglycan	839	842	PF01048	0.618
MOD_GlcNHglycan	846	849	PF01048	0.566
MOD_GlcNHglycan	874	877	PF01048	0.694
MOD_GlcNHglycan	881	884	PF01048	0.677
MOD_GlcNHglycan	889	892	PF01048	0.585
MOD_GlcNHglycan	918	921	PF01048	0.594
MOD_GSK3_1	105	112	PF00069	0.664
MOD_GSK3_1	114	121	PF00069	0.596
MOD_GSK3_1	122	129	PF00069	0.530
MOD_GSK3_1	151	158	PF00069	0.556
MOD_GSK3_1	165	172	PF00069	0.615
MOD_GSK3_1	17	24	PF00069	0.675
MOD_GSK3_1	203	210	PF00069	0.620
MOD_GSK3_1	293	300	PF00069	0.558
MOD_GSK3_1	301	308	PF00069	0.631
MOD_GSK3_1	32	39	PF00069	0.547
MOD_GSK3_1	337	344	PF00069	0.587
MOD_GSK3_1	353	360	PF00069	0.635
MOD_GSK3_1	362	369	PF00069	0.579
MOD_GSK3_1	381	388	PF00069	0.629
MOD_GSK3_1	429	436	PF00069	0.666
MOD_GSK3_1	49	56	PF00069	0.503
MOD_GSK3_1	521	528	PF00069	0.634
MOD_GSK3_1	544	551	PF00069	0.631
MOD_GSK3_1	556	563	PF00069	0.621
MOD_GSK3_1	601	608	PF00069	0.547
MOD_GSK3_1	617	624	PF00069	0.550
MOD_GSK3_1	636	643	PF00069	0.511
MOD_GSK3_1	704	711	PF00069	0.675
MOD_GSK3_1	719	726	PF00069	0.574
MOD_GSK3_1	736	743	PF00069	0.580
MOD_GSK3_1	753	760	PF00069	0.664
MOD_GSK3_1	780	787	PF00069	0.650
MOD_GSK3_1	809	816	PF00069	0.659
MOD_GSK3_1	825	832	PF00069	0.532
MOD_GSK3_1	833	840	PF00069	0.523
MOD_GSK3_1	850	857	PF00069	0.569
MOD_GSK3_1	870	877	PF00069	0.570
MOD_GSK3_1	882	889	PF00069	0.596
MOD_GSK3_1	912	919	PF00069	0.616
MOD_GSK3_1	924	931	PF00069	0.613
MOD_LATS_1	554	560	PF00433	0.679
MOD_N-GLC_1	293	298	PF02516	0.543
MOD_N-GLC_1	347	352	PF02516	0.677
MOD_N-GLC_1	680	685	PF02516	0.593
MOD_N-GLC_1	781	786	PF02516	0.676
MOD_N-GLC_1	854	859	PF02516	0.541
MOD_N-GLC_1	900	905	PF02516	0.590
MOD_NEK2_1	118	123	PF00069	0.519
MOD_NEK2_1	155	160	PF00069	0.576
MOD_NEK2_1	17	22	PF00069	0.537
MOD_NEK2_1	293	298	PF00069	0.543
MOD_NEK2_1	525	530	PF00069	0.683
MOD_NEK2_1	561	566	PF00069	0.620
MOD_NEK2_1	636	641	PF00069	0.655
MOD_NEK2_1	742	747	PF00069	0.524
MOD_NEK2_1	789	794	PF00069	0.751
MOD_NEK2_1	807	812	PF00069	0.519
MOD_NEK2_1	826	831	PF00069	0.665
MOD_NEK2_1	916	921	PF00069	0.612
MOD_NEK2_1	928	933	PF00069	0.570
MOD_NEK2_1	99	104	PF00069	0.622
MOD_NEK2_2	127	132	PF00069	0.663
MOD_NEK2_2	481	486	PF00069	0.545
MOD_PIKK_1	217	223	PF00454	0.606
MOD_PIKK_1	388	394	PF00454	0.684
MOD_PIKK_1	585	591	PF00454	0.534
MOD_PIKK_1	617	623	PF00454	0.671
MOD_PIKK_1	709	715	PF00454	0.681
MOD_PIKK_1	723	729	PF00454	0.573
MOD_PIKK_1	753	759	PF00454	0.715
MOD_PIKK_1	79	85	PF00454	0.565
MOD_PIKK_1	831	837	PF00454	0.815
MOD_PK_1	247	253	PF00069	0.620
MOD_PKA_1	240	246	PF00069	0.657
MOD_PKA_1	247	253	PF00069	0.626
MOD_PKA_1	30	36	PF00069	0.677
MOD_PKA_1	548	554	PF00069	0.676
MOD_PKA_1	602	608	PF00069	0.642
MOD_PKA_1	720	726	PF00069	0.689
MOD_PKA_1	844	850	PF00069	0.610
MOD_PKA_2	202	208	PF00069	0.677
MOD_PKA_2	230	236	PF00069	0.634
MOD_PKA_2	240	246	PF00069	0.551
MOD_PKA_2	247	253	PF00069	0.576
MOD_PKA_2	29	35	PF00069	0.622
MOD_PKA_2	337	343	PF00069	0.611
MOD_PKA_2	400	406	PF00069	0.681
MOD_PKA_2	476	482	PF00069	0.678
MOD_PKA_2	561	567	PF00069	0.621
MOD_PKA_2	574	580	PF00069	0.541
MOD_PKA_2	601	607	PF00069	0.653
MOD_PKA_2	608	614	PF00069	0.724
MOD_PKA_2	637	643	PF00069	0.530
MOD_PKA_2	703	709	PF00069	0.676
MOD_PKA_2	719	725	PF00069	0.565
MOD_PKA_2	765	771	PF00069	0.669
MOD_PKA_2	808	814	PF00069	0.525
MOD_PKB_1	600	608	PF00069	0.646
MOD_Plk_1	114	120	PF00069	0.668
MOD_Plk_1	123	129	PF00069	0.594
MOD_Plk_1	155	161	PF00069	0.641
MOD_Plk_1	269	275	PF00069	0.588
MOD_Plk_1	490	496	PF00069	0.537
MOD_Plk_1	662	668	PF00069	0.421
MOD_Plk_1	781	787	PF00069	0.827
MOD_Plk_1	826	832	PF00069	0.667
MOD_Plk_2-3	109	115	PF00069	0.667
MOD_Plk_2-3	44	50	PF00069	0.645
MOD_Plk_4	247	253	PF00069	0.545
MOD_Plk_4	276	282	PF00069	0.622
MOD_Plk_4	394	400	PF00069	0.682
MOD_Plk_4	44	50	PF00069	0.693
MOD_Plk_4	602	608	PF00069	0.797
MOD_Plk_4	637	643	PF00069	0.530
MOD_Plk_4	784	790	PF00069	0.831
MOD_ProDKin_1	10	16	PF00069	0.634
MOD_ProDKin_1	159	165	PF00069	0.517
MOD_ProDKin_1	204	210	PF00069	0.675
MOD_ProDKin_1	285	291	PF00069	0.601
MOD_ProDKin_1	3	9	PF00069	0.708
MOD_ProDKin_1	302	308	PF00069	0.549
MOD_ProDKin_1	316	322	PF00069	0.645
MOD_ProDKin_1	32	38	PF00069	0.670
MOD_ProDKin_1	332	338	PF00069	0.557
MOD_ProDKin_1	357	363	PF00069	0.662
MOD_ProDKin_1	381	387	PF00069	0.678
MOD_ProDKin_1	412	418	PF00069	0.593
MOD_ProDKin_1	420	426	PF00069	0.640
MOD_ProDKin_1	429	435	PF00069	0.588
MOD_ProDKin_1	450	456	PF00069	0.685
MOD_ProDKin_1	492	498	PF00069	0.670
MOD_ProDKin_1	704	710	PF00069	0.675
MOD_ProDKin_1	736	742	PF00069	0.762
MOD_ProDKin_1	790	796	PF00069	0.667
MOD_ProDKin_1	854	860	PF00069	0.590
MOD_ProDKin_1	874	880	PF00069	0.565
MOD_SUMO_for_1	505	508	PF00179	0.558
MOD_SUMO_rev_2	287	293	PF00179	0.524
MOD_SUMO_rev_2	484	494	PF00179	0.667
MOD_SUMO_rev_2	653	662	PF00179	0.448
TRG_DiLeu_BaEn_1	94	99	PF01217	0.556
TRG_ENDOCYTIC_2	945	948	PF00928	0.483
TRG_ER_diArg_1	131	134	PF00400	0.662
TRG_ER_diArg_1	147	149	PF00400	0.513
TRG_ER_diArg_1	599	602	PF00400	0.661
TRG_ER_diArg_1	62	65	PF00400	0.659
TRG_ER_diArg_1	645	647	PF00400	0.512
TRG_ER_diArg_1	666	669	PF00400	0.524
TRG_ER_diArg_1	91	93	PF00400	0.532
TRG_NLS_MonoExtN_4	545	552	PF00514	0.607

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3Q8IH67	Leishmania donovani	82%	100%
A4I8I7	Leishmania infantum	82%	100%
Q4Q4Q3	Leishmania major	78%	100%