Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9B3E3_LEIMU

TriTrypDb:

LmxM.31.3630

Length:

312

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B3E3

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B3E3

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
DEG_Nend_UBRbox_2	1	3	PF02207	0.654
DEG_SCF_FBW7_1	123	128	PF00400	0.623
DOC_CYCLIN_yCln2_LP_2	300	306	PF00134	0.698
DOC_MAPK_gen_1	214	222	PF00069	0.501
DOC_PP2B_LxvP_1	103	106	PF13499	0.817
DOC_PP2B_LxvP_1	300	303	PF13499	0.675
DOC_USP7_MATH_1	115	119	PF00917	0.716
DOC_USP7_MATH_1	15	19	PF00917	0.667
DOC_USP7_MATH_1	167	171	PF00917	0.720
DOC_USP7_MATH_1	254	258	PF00917	0.628
DOC_USP7_MATH_1	286	290	PF00917	0.667
DOC_USP7_MATH_1	304	308	PF00917	0.503
DOC_USP7_MATH_1	61	65	PF00917	0.631
DOC_USP7_MATH_1	75	79	PF00917	0.734
DOC_USP7_MATH_1	8	12	PF00917	0.819
DOC_USP7_MATH_1	98	102	PF00917	0.762
DOC_WW_Pin1_4	121	126	PF00397	0.762
DOC_WW_Pin1_4	13	18	PF00397	0.719
DOC_WW_Pin1_4	53	58	PF00397	0.509
DOC_WW_Pin1_4	91	96	PF00397	0.547
LIG_14-3-3_CanoR_1	214	222	PF00244	0.501
LIG_14-3-3_CanoR_1	228	237	PF00244	0.604
LIG_14-3-3_CanoR_1	27	36	PF00244	0.656
LIG_Actin_WH2_2	251	267	PF00022	0.540
LIG_CaM_IQ_9	235	250	PF13499	0.525
LIG_CSL_BTD_1	207	210	PF09270	0.535
LIG_EH1_1	137	145	PF00400	0.601
LIG_FHA_1	126	132	PF00498	0.649
LIG_FHA_2	285	291	PF00498	0.645
LIG_GBD_Chelix_1	292	300	PF00786	0.652
LIG_LIR_Nem_3	205	211	PF02991	0.472
LIG_LIR_Nem_3	38	43	PF02991	0.618
LIG_Pex14_1	208	212	PF04695	0.523
LIG_SH2_CRK	212	216	PF00017	0.493
LIG_SH2_GRB2like	221	224	PF00017	0.542
LIG_SH2_NCK_1	36	40	PF00017	0.448
LIG_SH2_SRC	36	39	PF00017	0.667
LIG_SH2_STAP1	43	47	PF00017	0.713
LIG_SH2_STAT3	236	239	PF00017	0.511
LIG_SH2_STAT5	221	224	PF00017	0.612
LIG_SH2_STAT5	236	239	PF00017	0.412
LIG_SH2_STAT5	47	50	PF00017	0.532
LIG_SH3_3	204	210	PF00018	0.633
LIG_TRAF2_1	89	92	PF00917	0.792
MOD_CK1_1	101	107	PF00069	0.710
MOD_CK1_1	11	17	PF00069	0.837
MOD_CK1_1	231	237	PF00069	0.507
MOD_CK1_1	94	100	PF00069	0.712
MOD_CK2_1	60	66	PF00069	0.587
MOD_DYRK1A_RPxSP_1	13	17	PF00069	0.757
MOD_GlcNHglycan	100	103	PF01048	0.657
MOD_GlcNHglycan	117	120	PF01048	0.607
MOD_GlcNHglycan	13	16	PF01048	0.665
MOD_GlcNHglycan	2	5	PF01048	0.746
MOD_GlcNHglycan	230	233	PF01048	0.503
MOD_GlcNHglycan	273	278	PF01048	0.535
MOD_GlcNHglycan	296	299	PF01048	0.641
MOD_GlcNHglycan	71	74	PF01048	0.673
MOD_GlcNHglycan	77	81	PF01048	0.709
MOD_GlcNHglycan	8	11	PF01048	0.702
MOD_GlcNHglycan	96	99	PF01048	0.510
MOD_GSK3_1	11	18	PF00069	0.625
MOD_GSK3_1	117	124	PF00069	0.668
MOD_GSK3_1	125	132	PF00069	0.685
MOD_GSK3_1	210	217	PF00069	0.521
MOD_GSK3_1	224	231	PF00069	0.558
MOD_GSK3_1	273	280	PF00069	0.496
MOD_GSK3_1	94	101	PF00069	0.676
MOD_NEK2_1	215	220	PF00069	0.498
MOD_PIKK_1	189	195	PF00454	0.564
MOD_PIKK_1	304	310	PF00454	0.749
MOD_PIKK_1	8	14	PF00454	0.721
MOD_PKA_2	242	248	PF00069	0.529
MOD_PKA_2	28	34	PF00069	0.645
MOD_PKA_2	83	89	PF00069	0.765
MOD_Plk_1	98	104	PF00069	0.699
MOD_Plk_4	231	237	PF00069	0.607
MOD_ProDKin_1	121	127	PF00069	0.756
MOD_ProDKin_1	13	19	PF00069	0.719
MOD_ProDKin_1	53	59	PF00069	0.511
MOD_ProDKin_1	91	97	PF00069	0.545
MOD_SUMO_for_1	271	274	PF00179	0.377
MOD_SUMO_rev_2	171	180	PF00179	0.654
MOD_SUMO_rev_2	218	227	PF00179	0.605
TRG_DiLeu_BaEn_1	288	293	PF01217	0.481
TRG_ENDOCYTIC_2	212	215	PF00928	0.442
TRG_ER_diArg_1	26	29	PF00400	0.710
TRG_ER_diArg_1	267	270	PF00400	0.643

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IK58	Leptomonas seymouri	39%	70%
A0A3Q8IJP5	Leishmania donovani	87%	71%
A4HL02	Leishmania braziliensis	68%	100%
E9AHM4	Leishmania infantum	87%	84%
Q4Q4Q9	Leishmania major	84%	100%