Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9B3E0_LEIMU

TriTrypDb:

LmxM.31.3600

Length:

200

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B3E0

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B3E0

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	164	168	PF00656	0.487
CLV_NRD_NRD_1	59	61	PF00675	0.536
CLV_NRD_NRD_1	7	9	PF00675	0.592
CLV_PCSK_KEX2_1	59	61	PF00082	0.536
CLV_PCSK_KEX2_1	7	9	PF00082	0.592
CLV_PCSK_SKI1_1	170	174	PF00082	0.510
CLV_PCSK_SKI1_1	177	181	PF00082	0.458
CLV_PCSK_SKI1_1	196	200	PF00082	0.488
CLV_PCSK_SKI1_1	67	71	PF00082	0.503
CLV_Separin_Metazoa	106	110	PF03568	0.546
CLV_Separin_Metazoa	68	72	PF03568	0.511
DEG_APCC_DBOX_1	169	177	PF00400	0.562
DEG_APCC_DBOX_1	66	74	PF00400	0.516
DOC_MAPK_gen_1	32	41	PF00069	0.599
DOC_MAPK_MEF2A_6	71	78	PF00069	0.487
DOC_MAPK_NFAT4_5	71	79	PF00069	0.489
DOC_PP2B_LxvP_1	144	147	PF13499	0.591
DOC_USP7_MATH_1	152	156	PF00917	0.637
LIG_14-3-3_CanoR_1	7	15	PF00244	0.522
LIG_BIR_II_1	1	5	PF00653	0.604
LIG_FHA_1	141	147	PF00498	0.582
LIG_FHA_1	18	24	PF00498	0.451
LIG_FHA_1	32	38	PF00498	0.557
LIG_FHA_1	98	104	PF00498	0.521
LIG_FHA_2	162	168	PF00498	0.535
LIG_FHA_2	63	69	PF00498	0.501
LIG_LIR_Nem_3	63	69	PF02991	0.444
LIG_NRBOX	69	75	PF00104	0.523
LIG_PDZ_Class_2	195	200	PF00595	0.499
LIG_SH2_STAT5	22	25	PF00017	0.557
LIG_TRAF2_1	40	43	PF00917	0.458
MOD_CK1_1	168	174	PF00069	0.497
MOD_CK1_1	2	8	PF00069	0.637
MOD_CK1_1	9	15	PF00069	0.581
MOD_CK2_1	168	174	PF00069	0.657
MOD_CK2_1	62	68	PF00069	0.503
MOD_GlcNHglycan	10	14	PF01048	0.587
MOD_GlcNHglycan	100	103	PF01048	0.470
MOD_GlcNHglycan	154	157	PF01048	0.647
MOD_GlcNHglycan	170	173	PF01048	0.389
MOD_GlcNHglycan	84	87	PF01048	0.576
MOD_GSK3_1	157	164	PF00069	0.558
MOD_GSK3_1	190	197	PF00069	0.553
MOD_GSK3_1	2	9	PF00069	0.637
MOD_GSK3_1	80	87	PF00069	0.621
MOD_PIKK_1	116	122	PF00454	0.516
MOD_PK_1	125	131	PF00069	0.486
MOD_PKA_2	31	37	PF00069	0.451
MOD_PKA_2	6	12	PF00069	0.588
MOD_Plk_1	17	23	PF00069	0.399
MOD_Plk_1	187	193	PF00069	0.458
MOD_Plk_1	62	68	PF00069	0.331
MOD_Plk_4	125	131	PF00069	0.353
MOD_Plk_4	187	193	PF00069	0.458
MOD_SUMO_for_1	179	182	PF00179	0.447
MOD_SUMO_rev_2	174	181	PF00179	0.495
TRG_ENDOCYTIC_2	66	69	PF00928	0.364
TRG_ER_diArg_1	58	60	PF00400	0.499
TRG_ER_diArg_1	6	8	PF00400	0.737
TRG_NES_CRM1_1	68	82	PF08389	0.539

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1HVP8	Leptomonas seymouri	33%	97%
A0A3Q8ILP4	Leishmania donovani	88%	100%
A4HKZ9	Leishmania braziliensis	63%	100%
A4I8I0	Leishmania infantum	88%	100%
Q4Q4R2	Leishmania major	88%	100%