Transmembrane protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9B3D9_LEIMU

TriTrypDb:

LmxM.31.3590

Length:

112

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 9
NetGPI	no	yes: 0, no: 9

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Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	9
GO:0110165	cellular anatomical entity	1	9

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Expansion

Sequence features

E9B3D9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B3D9

Putative motif mimicry

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Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	80	82	PF00675	0.417
CLV_PCSK_KEX2_1	79	81	PF00082	0.436
DOC_CYCLIN_yCln2_LP_2	55	61	PF00134	0.369
DOC_PP2B_LxvP_1	55	58	PF13499	0.333
DOC_USP7_MATH_1	51	55	PF00917	0.242
DOC_USP7_MATH_1	61	65	PF00917	0.453
LIG_14-3-3_CanoR_1	80	90	PF00244	0.732
LIG_Actin_WH2_2	62	77	PF00022	0.485
LIG_BRCT_BRCA1_1	62	66	PF00533	0.485
LIG_FHA_1	15	21	PF00498	0.697

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PBG0	Leptomonas seymouri	57%	92%
A0A1X0NRX6	Trypanosomatidae	37%	94%
A0A3R7LD90	Trypanosoma rangeli	36%	94%
A0A3S7X638	Leishmania donovani	88%	96%
A4I8H9	Leishmania infantum	89%	96%
E9AIV3	Leishmania braziliensis	85%	100%
Q4Q4R3	Leishmania major	80%	100%
V5DMF6	Trypanosoma cruzi	32%	94%

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