DBP

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

DBP

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9B3D4_LEIMU

TriTrypDb:

LmxM.31.3500

Length:

301

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B3D4

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B3D4

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	18	22	PF00656	0.745
CLV_C14_Caspase3-7	224	228	PF00656	0.653
CLV_PCSK_KEX2_1	57	59	PF00082	0.390
CLV_PCSK_PC1ET2_1	57	59	PF00082	0.448
CLV_PCSK_SKI1_1	39	43	PF00082	0.547
CLV_PCSK_SKI1_1	46	50	PF00082	0.520
CLV_PCSK_SKI1_1	58	62	PF00082	0.369
DOC_CKS1_1	160	165	PF01111	0.619
DOC_MAPK_gen_1	258	266	PF00069	0.610
DOC_MAPK_MEF2A_6	258	266	PF00069	0.354
DOC_PP4_FxxP_1	145	148	PF00568	0.574
DOC_PP4_FxxP_1	288	291	PF00568	0.657
DOC_USP7_MATH_1	107	111	PF00917	0.638
DOC_USP7_MATH_1	133	137	PF00917	0.276
DOC_USP7_MATH_1	226	230	PF00917	0.653
DOC_USP7_UBL2_3	104	108	PF12436	0.338
DOC_USP7_UBL2_3	243	247	PF12436	0.646
DOC_USP7_UBL2_3	57	61	PF12436	0.585
DOC_WW_Pin1_4	159	164	PF00397	0.614
LIG_14-3-3_CanoR_1	149	155	PF00244	0.573
LIG_14-3-3_CanoR_1	39	49	PF00244	0.422
LIG_14-3-3_CanoR_1	80	86	PF00244	0.487
LIG_Actin_WH2_2	253	270	PF00022	0.308
LIG_eIF4E_1	113	119	PF01652	0.601
LIG_FHA_1	184	190	PF00498	0.510
LIG_FHA_1	231	237	PF00498	0.565
LIG_FHA_1	80	86	PF00498	0.456
LIG_FHA_1	88	94	PF00498	0.413
LIG_FHA_2	18	24	PF00498	0.584
LIG_FHA_2	250	256	PF00498	0.337
LIG_LIR_Apic_2	136	142	PF02991	0.422
LIG_LIR_Gen_1	153	161	PF02991	0.587
LIG_LIR_Gen_1	34	45	PF02991	0.631
LIG_LIR_Nem_3	153	157	PF02991	0.585
LIG_LIR_Nem_3	34	40	PF02991	0.560
LIG_LIR_Nem_3	59	65	PF02991	0.571
LIG_NRBOX	156	162	PF00104	0.595
LIG_PCNA_yPIPBox_3	114	128	PF02747	0.400
LIG_Pex14_2	49	53	PF04695	0.357
LIG_SH2_CRK	115	119	PF00017	0.596
LIG_SH2_CRK	139	143	PF00017	0.451
LIG_SH2_CRK	218	222	PF00017	0.603
LIG_SH2_PTP2	154	157	PF00017	0.534
LIG_SH2_STAP1	115	119	PF00017	0.515
LIG_SH2_STAT5	102	105	PF00017	0.589
LIG_SH2_STAT5	154	157	PF00017	0.588
LIG_SH2_STAT5	199	202	PF00017	0.660
LIG_TRAF2_1	15	18	PF00917	0.793
LIG_TYR_ITIM	152	157	PF00017	0.581
LIG_UBA3_1	262	268	PF00899	0.357
MOD_CK1_1	153	159	PF00069	0.562
MOD_CK1_1	71	77	PF00069	0.610
MOD_CK2_1	249	255	PF00069	0.601
MOD_CK2_1	289	295	PF00069	0.725
MOD_GlcNHglycan	49	52	PF01048	0.627
MOD_GlcNHglycan	8	12	PF01048	0.511
MOD_GSK3_1	226	233	PF00069	0.639
MOD_GSK3_1	3	10	PF00069	0.544
MOD_GSK3_1	47	54	PF00069	0.607
MOD_N-GLC_1	216	221	PF02516	0.356
MOD_NEK2_1	1	6	PF00069	0.523
MOD_NEK2_1	190	195	PF00069	0.405
MOD_NEK2_1	230	235	PF00069	0.553
MOD_NEK2_1	249	254	PF00069	0.361
MOD_NEK2_1	47	52	PF00069	0.609
MOD_NEK2_1	79	84	PF00069	0.582
MOD_NEK2_2	9	14	PF00069	0.502
MOD_PIKK_1	190	196	PF00454	0.523
MOD_PKA_1	207	213	PF00069	0.649
MOD_PKA_2	171	177	PF00069	0.753
MOD_PKA_2	79	85	PF00069	0.467
MOD_Plk_1	216	222	PF00069	0.354
MOD_Plk_2-3	17	23	PF00069	0.742
MOD_Plk_4	107	113	PF00069	0.572
MOD_Plk_4	150	156	PF00069	0.265
MOD_Plk_4	216	222	PF00069	0.610
MOD_Plk_4	275	281	PF00069	0.533
MOD_ProDKin_1	159	165	PF00069	0.615
MOD_SUMO_rev_2	100	110	PF00179	0.371
TRG_ENDOCYTIC_2	115	118	PF00928	0.601
TRG_ENDOCYTIC_2	154	157	PF00928	0.588
TRG_ENDOCYTIC_2	218	221	PF00928	0.605
TRG_ENDOCYTIC_2	62	65	PF00928	0.619
TRG_NES_CRM1_1	23	34	PF08389	0.405
TRG_Pf-PMV_PEXEL_1	14	18	PF00026	0.616

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3Q8IH56	Leishmania donovani	86%	100%
A4HKZ3	Leishmania braziliensis	71%	100%
A4I8H4	Leishmania infantum	86%	100%
E9AEG9	Leishmania major	83%	66%