Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9B3B1_LEIMU

TriTrypDb:

LmxM.31.3280

Length:

815

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B3B1

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B3B1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	194	198	PF00656	0.478
CLV_NRD_NRD_1	208	210	PF00675	0.542
CLV_NRD_NRD_1	226	228	PF00675	0.498
CLV_NRD_NRD_1	425	427	PF00675	0.598
CLV_NRD_NRD_1	445	447	PF00675	0.523
CLV_NRD_NRD_1	481	483	PF00675	0.688
CLV_NRD_NRD_1	501	503	PF00675	0.583
CLV_NRD_NRD_1	546	548	PF00675	0.486
CLV_NRD_NRD_1	587	589	PF00675	0.596
CLV_NRD_NRD_1	662	664	PF00675	0.502
CLV_PCSK_FUR_1	423	427	PF00082	0.529
CLV_PCSK_FUR_1	544	548	PF00082	0.486
CLV_PCSK_KEX2_1	208	210	PF00082	0.542
CLV_PCSK_KEX2_1	226	228	PF00082	0.498
CLV_PCSK_KEX2_1	425	427	PF00082	0.670
CLV_PCSK_KEX2_1	481	483	PF00082	0.583
CLV_PCSK_KEX2_1	546	548	PF00082	0.486
CLV_PCSK_KEX2_1	587	589	PF00082	0.596
CLV_PCSK_KEX2_1	662	664	PF00082	0.508
CLV_PCSK_KEX2_1	776	778	PF00082	0.597
CLV_PCSK_KEX2_1	809	811	PF00082	0.808
CLV_PCSK_PC1ET2_1	776	778	PF00082	0.644
CLV_PCSK_PC1ET2_1	809	811	PF00082	0.687
CLV_PCSK_PC7_1	204	210	PF00082	0.530
CLV_PCSK_PC7_1	658	664	PF00082	0.504
CLV_PCSK_SKI1_1	161	165	PF00082	0.647
CLV_PCSK_SKI1_1	220	224	PF00082	0.681
CLV_PCSK_SKI1_1	227	231	PF00082	0.604
CLV_PCSK_SKI1_1	357	361	PF00082	0.633
CLV_PCSK_SKI1_1	400	404	PF00082	0.601
CLV_PCSK_SKI1_1	437	441	PF00082	0.553
CLV_PCSK_SKI1_1	620	624	PF00082	0.625
CLV_PCSK_SKI1_1	663	667	PF00082	0.573
DEG_COP1_1	166	173	PF00400	0.471
DEG_COP1_1	353	365	PF00400	0.668
DEG_SCF_FBW7_2	211	216	PF00400	0.524
DEG_SPOP_SBC_1	621	625	PF00917	0.706
DEG_SPOP_SBC_1	793	797	PF00917	0.658
DOC_CKS1_1	170	175	PF01111	0.474
DOC_CKS1_1	210	215	PF01111	0.662
DOC_CKS1_1	372	377	PF01111	0.674
DOC_CKS1_1	58	63	PF01111	0.640
DOC_MAPK_DCC_7	15	25	PF00069	0.454
DOC_MAPK_DCC_7	761	769	PF00069	0.608
DOC_MAPK_gen_1	544	553	PF00069	0.563
DOC_MAPK_MEF2A_6	331	340	PF00069	0.559
DOC_MAPK_MEF2A_6	544	553	PF00069	0.563
DOC_MAPK_MEF2A_6	761	769	PF00069	0.608
DOC_PP2B_LxvP_1	168	171	PF13499	0.569
DOC_PP2B_LxvP_1	369	372	PF13499	0.620
DOC_PP2B_LxvP_1	713	716	PF13499	0.473
DOC_PP2B_PxIxI_1	333	339	PF00149	0.562
DOC_PP4_FxxP_1	18	21	PF00568	0.585
DOC_PP4_FxxP_1	648	651	PF00568	0.489
DOC_USP7_MATH_1	121	125	PF00917	0.408
DOC_USP7_MATH_1	129	133	PF00917	0.605
DOC_USP7_MATH_1	171	175	PF00917	0.681
DOC_USP7_MATH_1	196	200	PF00917	0.481
DOC_USP7_MATH_1	234	238	PF00917	0.623
DOC_USP7_MATH_1	350	354	PF00917	0.648
DOC_USP7_MATH_1	363	367	PF00917	0.774
DOC_USP7_MATH_1	450	454	PF00917	0.538
DOC_USP7_MATH_1	466	470	PF00917	0.677
DOC_USP7_MATH_1	52	56	PF00917	0.650
DOC_USP7_MATH_1	552	556	PF00917	0.599
DOC_USP7_MATH_1	559	563	PF00917	0.597
DOC_USP7_MATH_1	603	607	PF00917	0.627
DOC_USP7_MATH_1	630	634	PF00917	0.612
DOC_USP7_MATH_1	679	683	PF00917	0.614
DOC_USP7_MATH_1	691	695	PF00917	0.623
DOC_USP7_MATH_1	702	706	PF00917	0.564
DOC_USP7_MATH_1	792	796	PF00917	0.651
DOC_USP7_MATH_1	80	84	PF00917	0.544
DOC_USP7_MATH_2	247	253	PF00917	0.640
DOC_USP7_UBL2_3	772	776	PF12436	0.632
DOC_WW_Pin1_4	169	174	PF00397	0.474
DOC_WW_Pin1_4	209	214	PF00397	0.664
DOC_WW_Pin1_4	215	220	PF00397	0.588
DOC_WW_Pin1_4	228	233	PF00397	0.537
DOC_WW_Pin1_4	371	376	PF00397	0.636
DOC_WW_Pin1_4	407	412	PF00397	0.559
DOC_WW_Pin1_4	528	533	PF00397	0.631
DOC_WW_Pin1_4	54	59	PF00397	0.673
DOC_WW_Pin1_4	569	574	PF00397	0.730
DOC_WW_Pin1_4	592	597	PF00397	0.621
DOC_WW_Pin1_4	624	629	PF00397	0.609
DOC_WW_Pin1_4	686	691	PF00397	0.510
DOC_WW_Pin1_4	71	76	PF00397	0.513
DOC_WW_Pin1_4	735	740	PF00397	0.663
LIG_14-3-3_CanoR_1	126	133	PF00244	0.500
LIG_14-3-3_CanoR_1	143	152	PF00244	0.464
LIG_14-3-3_CanoR_1	201	207	PF00244	0.608
LIG_14-3-3_CanoR_1	220	225	PF00244	0.696
LIG_14-3-3_CanoR_1	226	232	PF00244	0.666
LIG_14-3-3_CanoR_1	264	269	PF00244	0.494
LIG_14-3-3_CanoR_1	620	630	PF00244	0.625
LIG_14-3-3_CanoR_1	757	765	PF00244	0.599
LIG_14-3-3_CanoR_1	810	814	PF00244	0.550
LIG_14-3-3_CanoR_1	84	89	PF00244	0.477
LIG_14-3-3_CterR_2	810	815	PF00244	0.562
LIG_Actin_WH2_2	173	191	PF00022	0.521
LIG_BIR_III_4	342	346	PF00653	0.476
LIG_BRCT_BRCA1_1	62	66	PF00533	0.700
LIG_CaM_NSCaTE_8	480	487	PF13499	0.641
LIG_FHA_1	110	116	PF00498	0.553
LIG_FHA_1	15	21	PF00498	0.663
LIG_FHA_1	170	176	PF00498	0.578
LIG_FHA_1	228	234	PF00498	0.537
LIG_FHA_1	333	339	PF00498	0.635
LIG_FHA_1	404	410	PF00498	0.705
LIG_FHA_1	459	465	PF00498	0.639
LIG_FHA_1	535	541	PF00498	0.736
LIG_FHA_1	595	601	PF00498	0.496
LIG_FHA_1	669	675	PF00498	0.450
LIG_FHA_1	77	83	PF00498	0.620
LIG_FHA_2	142	148	PF00498	0.501
LIG_FHA_2	427	433	PF00498	0.670
LIG_FHA_2	48	54	PF00498	0.685
LIG_LIR_Apic_2	17	21	PF02991	0.583
LIG_LIR_Gen_1	128	138	PF02991	0.425
LIG_LIR_Gen_1	13	23	PF02991	0.630
LIG_LIR_Gen_1	83	92	PF02991	0.448
LIG_LIR_Nem_3	128	133	PF02991	0.427
LIG_LIR_Nem_3	13	19	PF02991	0.630
LIG_LIR_Nem_3	83	88	PF02991	0.507
LIG_MAD2	620	628	PF02301	0.487
LIG_PDZ_Class_2	810	815	PF00595	0.542
LIG_Pex14_2	496	500	PF04695	0.475
LIG_REV1ctd_RIR_1	137	147	PF16727	0.540
LIG_SH2_CRK	16	20	PF00017	0.756
LIG_SH2_CRK	421	425	PF00017	0.579
LIG_SH2_PTP2	22	25	PF00017	0.459
LIG_SH2_SRC	752	755	PF00017	0.501
LIG_SH2_STAP1	16	20	PF00017	0.635
LIG_SH2_STAP1	752	756	PF00017	0.501
LIG_SH2_STAT5	16	19	PF00017	0.636
LIG_SH2_STAT5	22	25	PF00017	0.622
LIG_SH3_1	590	596	PF00018	0.602
LIG_SH3_3	167	173	PF00018	0.516
LIG_SH3_3	248	254	PF00018	0.619
LIG_SH3_3	267	273	PF00018	0.487
LIG_SH3_3	282	288	PF00018	0.741
LIG_SH3_3	299	305	PF00018	0.651
LIG_SH3_3	324	330	PF00018	0.692
LIG_SH3_3	369	375	PF00018	0.656
LIG_SH3_3	393	399	PF00018	0.562
LIG_SH3_3	409	415	PF00018	0.662
LIG_SH3_3	486	492	PF00018	0.633
LIG_SH3_3	519	525	PF00018	0.745
LIG_SH3_3	542	548	PF00018	0.614
LIG_SH3_3	55	61	PF00018	0.592
LIG_SH3_3	590	596	PF00018	0.602
LIG_SH3_3	72	78	PF00018	0.583
LIG_SH3_4	772	779	PF00018	0.637
LIG_SH3_CIN85_PxpxPR_1	411	416	PF14604	0.583
LIG_SUMO_SIM_anti_2	335	342	PF11976	0.622
LIG_SUMO_SIM_par_1	176	182	PF11976	0.519
LIG_SUMO_SIM_par_1	272	278	PF11976	0.666
LIG_SUMO_SIM_par_1	436	443	PF11976	0.529
LIG_SUMO_SIM_par_1	460	465	PF11976	0.504
LIG_SUMO_SIM_par_1	549	557	PF11976	0.559
LIG_TYR_ITIM	20	25	PF00017	0.454
LIG_WW_3	787	791	PF00397	0.516
MOD_CDK_SPK_2	215	220	PF00069	0.651
MOD_CDK_SPK_2	528	533	PF00069	0.590
MOD_CK1_1	218	224	PF00069	0.789
MOD_CK1_1	33	39	PF00069	0.616
MOD_CK1_1	361	367	PF00069	0.666
MOD_CK1_1	376	382	PF00069	0.513
MOD_CK1_1	388	394	PF00069	0.558
MOD_CK1_1	407	413	PF00069	0.565
MOD_CK1_1	465	471	PF00069	0.564
MOD_CK1_1	531	537	PF00069	0.668
MOD_CK1_1	568	574	PF00069	0.494
MOD_CK1_1	57	63	PF00069	0.662
MOD_CK1_1	624	630	PF00069	0.619
MOD_CK1_1	705	711	PF00069	0.669
MOD_CK1_1	83	89	PF00069	0.434
MOD_CK2_1	141	147	PF00069	0.499
MOD_CK2_1	176	182	PF00069	0.538
MOD_CK2_1	352	358	PF00069	0.676
MOD_CK2_1	426	432	PF00069	0.663
MOD_CK2_1	47	53	PF00069	0.658
MOD_CK2_1	56	62	PF00069	0.570
MOD_CK2_1	748	754	PF00069	0.519
MOD_GlcNHglycan	103	106	PF01048	0.564
MOD_GlcNHglycan	127	130	PF01048	0.562
MOD_GlcNHglycan	153	156	PF01048	0.582
MOD_GlcNHglycan	236	239	PF01048	0.546
MOD_GlcNHglycan	25	28	PF01048	0.579
MOD_GlcNHglycan	354	357	PF01048	0.655
MOD_GlcNHglycan	366	369	PF01048	0.796
MOD_GlcNHglycan	376	379	PF01048	0.634
MOD_GlcNHglycan	406	409	PF01048	0.641
MOD_GlcNHglycan	463	467	PF01048	0.769
MOD_GlcNHglycan	50	53	PF01048	0.620
MOD_GlcNHglycan	616	619	PF01048	0.515
MOD_GlcNHglycan	624	627	PF01048	0.686
MOD_GlcNHglycan	632	635	PF01048	0.600
MOD_GlcNHglycan	637	640	PF01048	0.545
MOD_GlcNHglycan	679	682	PF01048	0.633
MOD_GlcNHglycan	693	696	PF01048	0.573
MOD_GlcNHglycan	758	761	PF01048	0.685
MOD_GlcNHglycan	790	793	PF01048	0.653
MOD_GSK3_1	121	128	PF00069	0.551
MOD_GSK3_1	260	267	PF00069	0.553
MOD_GSK3_1	348	355	PF00069	0.635
MOD_GSK3_1	35	42	PF00069	0.646
MOD_GSK3_1	357	364	PF00069	0.735
MOD_GSK3_1	374	381	PF00069	0.559
MOD_GSK3_1	403	410	PF00069	0.638
MOD_GSK3_1	44	51	PF00069	0.559
MOD_GSK3_1	448	455	PF00069	0.691
MOD_GSK3_1	458	465	PF00069	0.533
MOD_GSK3_1	52	59	PF00069	0.528
MOD_GSK3_1	554	561	PF00069	0.610
MOD_GSK3_1	565	572	PF00069	0.699
MOD_GSK3_1	603	610	PF00069	0.571
MOD_GSK3_1	62	69	PF00069	0.623
MOD_GSK3_1	620	627	PF00069	0.516
MOD_GSK3_1	630	637	PF00069	0.606
MOD_GSK3_1	668	675	PF00069	0.543
MOD_GSK3_1	677	684	PF00069	0.606
MOD_GSK3_1	718	725	PF00069	0.642
MOD_GSK3_1	735	742	PF00069	0.591
MOD_GSK3_1	74	81	PF00069	0.543
MOD_GSK3_1	788	795	PF00069	0.772
MOD_GSK3_1	84	91	PF00069	0.480
MOD_LATS_1	262	268	PF00433	0.495
MOD_LATS_1	798	804	PF00433	0.657
MOD_N-GLC_1	382	387	PF02516	0.625
MOD_N-GLC_1	403	408	PF02516	0.564
MOD_N-GLC_1	614	619	PF02516	0.503
MOD_N-GLC_1	635	640	PF02516	0.718
MOD_N-GLC_1	800	805	PF02516	0.724
MOD_N-GLC_2	605	607	PF02516	0.527
MOD_NEK2_1	30	35	PF00069	0.628
MOD_NEK2_1	390	395	PF00069	0.653
MOD_NEK2_1	403	408	PF00069	0.651
MOD_NEK2_1	462	467	PF00069	0.499
MOD_NEK2_1	484	489	PF00069	0.695
MOD_NEK2_1	583	588	PF00069	0.580
MOD_NEK2_1	609	614	PF00069	0.589
MOD_NEK2_1	622	627	PF00069	0.521
MOD_NEK2_1	66	71	PF00069	0.636
MOD_NEK2_1	756	761	PF00069	0.619
MOD_NEK2_2	121	126	PF00069	0.521
MOD_OFUCOSY	602	607	PF10250	0.537
MOD_OFUCOSY	703	709	PF10250	0.466
MOD_PIKK_1	33	39	PF00454	0.574
MOD_PIKK_1	581	587	PF00454	0.588
MOD_PIKK_1	609	615	PF00454	0.641
MOD_PK_1	264	270	PF00069	0.623
MOD_PK_1	84	90	PF00069	0.516
MOD_PKA_1	809	815	PF00069	0.626
MOD_PKA_2	125	131	PF00069	0.492
MOD_PKA_2	156	162	PF00069	0.523
MOD_PKA_2	756	762	PF00069	0.581
MOD_PKA_2	809	815	PF00069	0.641
MOD_PKA_2	83	89	PF00069	0.501
MOD_Plk_1	357	363	PF00069	0.630
MOD_Plk_1	385	391	PF00069	0.491
MOD_Plk_2-3	62	68	PF00069	0.602
MOD_Plk_4	14	20	PF00069	0.632
MOD_Plk_4	148	154	PF00069	0.590
MOD_Plk_4	220	226	PF00069	0.560
MOD_Plk_4	398	404	PF00069	0.592
MOD_Plk_4	496	502	PF00069	0.585
MOD_ProDKin_1	169	175	PF00069	0.473
MOD_ProDKin_1	209	215	PF00069	0.663
MOD_ProDKin_1	228	234	PF00069	0.636
MOD_ProDKin_1	371	377	PF00069	0.637
MOD_ProDKin_1	407	413	PF00069	0.559
MOD_ProDKin_1	528	534	PF00069	0.629
MOD_ProDKin_1	54	60	PF00069	0.674
MOD_ProDKin_1	569	575	PF00069	0.732
MOD_ProDKin_1	592	598	PF00069	0.621
MOD_ProDKin_1	624	630	PF00069	0.607
MOD_ProDKin_1	686	692	PF00069	0.513
MOD_ProDKin_1	71	77	PF00069	0.512
MOD_ProDKin_1	735	741	PF00069	0.665
MOD_SUMO_rev_2	104	112	PF00179	0.504
TRG_DiLeu_BaEn_1	661	666	PF01217	0.522
TRG_DiLeu_BaLyEn_6	648	653	PF01217	0.482
TRG_ENDOCYTIC_2	16	19	PF00928	0.691
TRG_ENDOCYTIC_2	22	25	PF00928	0.550
TRG_ER_diArg_1	225	227	PF00400	0.521
TRG_ER_diArg_1	423	426	PF00400	0.622
TRG_ER_diArg_1	480	482	PF00400	0.640
TRG_ER_diArg_1	543	546	PF00400	0.492
TRG_ER_diArg_1	587	590	PF00400	0.599
TRG_Pf-PMV_PEXEL_1	672	677	PF00026	0.509

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PC13	Leptomonas seymouri	36%	97%
A0A3S7X647	Leishmania donovani	79%	98%
A4HKX3	Leishmania braziliensis	46%	100%
A4I8F3	Leishmania infantum	79%	98%
Q4Q4U4	Leishmania major	77%	100%